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CCTG Connection



Published:
Category: Publications
Publication: CO28 correlative A follow up correlative study from the CCTG CO28 trial
 
The Canadian Cancer Trials Group (CCTG) CO.28 trial demonstrated that neoadjuvant chemotherapy followed by transanal excision was an effective treatment approach for patients with cT1–3, node-negative (N0) rectal cancer.
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Published:
Category: Publications
Publication: CXC2 Primary

CXC2 is a Randomized Phase III Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer

Incorporation of triapine (T) to cisplatin chemoradiation (CRT) for locally advanced cervical and vaginal cancer: Results from NRG-GY006

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Published:
Category: Publications
CCTG at International Myeloma Society Meeting September 23-26

It was great to see such a strong Canadian research presence at the International Myeloma Society (IMS) Annual Meeting, held September 23–26, 2026, in Glasgow, Scotland.

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Published:
Category: Publications
ASTRO's 68th Annual Meeting — the leading global conference in radiation oncology
American Society for Therapeutic Radiology and Oncology (ASTRO) 68th Annual Meeting was held September 26-30 included here are some of the scientific presented trial outcomes that CCTG participated in. Read More



Published:
Category: Group updates
Health Canada publishes GUI-0100 version 4

 

On August 14, 2026 Health Canada released an updated guidance that replaces Guidance Document: Part C, Division 5 of the Food and Drug Regulations "Drugs for Clinical Trials Involving Human Subjects" (GUI-0100), version 3

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Published:
Category: Group updates
Seeking Patient Representative for the Breast Disease Site Committee
The Canadian Cancer Trials Group (CCTG) is currently seeking applications for a Patient Representative for the Breast Disease Site Committee. CCTG is an inclusive organization dedicated to building a diverse national network, so we are strongly considering applications for patient representation from Quebec, New Brunswick, Nova Scotia, PEI or Newfoundland and Labrador for this position. Read More

Published:
Category: Publications
Publication: non-small cell lung cancer review
Association of tumor mutational burden and tumor-infiltrating lymphocytes with second primary cancer after complete resection of non-small cell lung cancer
 
The risk of developing second primary cancers (SPC) after complete surgical resection of non-small cell lung cancer (NSCLC) has been estimated at 1-2% per patient-year.
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Published:
Category: Publications
Publication: VU2 review
 Vulvar Squamous Cell Carcinoma: Scientific Progress and Impacts to Pathology Practice
 
Despite vulvar cancer’s rarity, meaningful advances have been made to improve the clinical care of affected patients—particularly with respect to vulvar squamous cell carcinoma (VSCC). These advances are reflected in changes to tumor classification, surgical strategies, early detection of precursors, and targeted therapeutic exploration.
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