A Phase III International Randomized Trial of Single Versus Multiple Fractions for Re-Irradiation of Painful Bone Metastases
Complexity Level: 2
Eligibility: Patients with painful bone metastases after previous palliative radiotherapy had been given to the diseased bone.
Objectives: To assess the factors that influence response to re-irradiation and to determine the incidence of severe radiation side effects.
NCT Registration ID (from clinicaltrials.gov): NCT00080912
Participation: Not Limited.
NCI US Affiliation: No
Clinical Trials Application (Canada): No
Coordination: NCIC CTG Led Trial
Status: Permanently Closed
Activation Date: January 07, 2004 Closing Date: May 24, 2012
Chair: (Australia) Dr. Daniel Roos, Royal Adelaide Hospital, (8) 8222-4000, (France) Dr. Jean-Leon Lagrange, Assistance Publique Hopitaux de Paris (APHP), (14) 981-4524, (USA) Dr. William Hartsell, Advocate Good Samaritan Cancer Center, (630) 275-2300, (The Netherlands) Dr. Yvette van der Linden, Radiotherapeutic Institution Friesland, (58) 286-6667, (UK) Dr. Peter Hoskin, Univ. College of London Clinical Trials Unit, (1923) 844533, (Canada) Dr. Jackson Wu, Tom Baker Cancer Centre, (403) 521-3095, (Canada) Dr. Edward L.W. Chow, Odette Cancer Centre, (416) 480-4998