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Clinical Trials

The Canadian Cancer Trials Group (CCTG) supports national and international multicentre phase I-III cancer clinical research trials aimed at improving the survival and quality of life of cancer patients across all cancer types. The scientific agenda for the group is developed by clinical researchers across Canada and beyond, includes trials of new cancer agents, novel radiation and surgical techniques, as well as interventions to improve patient quality of life.

If you are a CCTG member and need to access the full trials pages please click here.

The links below will take you to pages that list all the current CCTG trials with a brief description. If you are interested in volunteering for a trial we suggest that you discuss the opportunity with your care team.

If you are a patient or caregiver and are looking for other information about clinical trials a complete listing of clinical trials being conducted in Canada, including the locations where they are being conducted, can be found here: Canadian Cancer Trials.  And if you are interested in learning about participating in a clinical trial more information can be found here: www.itstartswithme.ca

 

How can I participate in a clinical trial

 

How can I participate in a clinical trial

New SC32S survey study opens across Canada

New SC32S survey study opens across Canada

A new survey study SC32S, collecting sociodemographic data from clinical trial participants, has now opened across Canada. This study will help researchers understand the feasibility of using a survey to gather information about trial participants’ backgrounds and everyday lives.

“We still do not have a clear picture of who is participating in Canadian cancer clinical trials, and who may be missing,” says study co-chair Dr. Leah Lambert, Executive Director and Senior Scientist of the Nursing and Allied Health Research and Knowledge Translation at BC Cancer. “SC32S will help us understand whether we can collect these data in a way that feels appropriate and acceptable to patients, and whether our trials reflect the communities we aim to serve.”

The information collected in the survey is referred to as sociodemographic data—a combination of social and demographic information. The survey will ask CCTG trial participants about different parts of everyday life that can affect patient health.

Canadian research does not routinely collect information about the backgrounds of trial participants. Collecting this information will help researchers better understand who takes part in clinical trials and whether certain groups face barriers to participation. Learning more about the backgrounds of participants will also help ensure clinical cancer research is equitable and reflects the diversity of Canadians.

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Now open, the SC30 study investigating the role of immunoglobulin and antibiotics on infections in patients with blood cancers

Now open, the SC30 study investigating the role of immunoglobulin and antibiotics on infections in patients with blood cancers

The new SC30 RATIONAL-PT international study is now open in Canada and will compare different approaches to preventing infections in people with blood cancers with low antibody levels. People with blood cancers often develop low levels of antibodies that can lead to an increased chance of developing an infection.

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DYNAMIC-III (CO.29) clinical trial were presented during the Presidential Symposium of the European Society for Medical Oncology Congress in Berlin

Trial results show that a blood test can guide treatment decisions in advanced colon cancer

Results from the primary analysis of the ctDNA-negative cohort from the international DYNAMIC-III (CO.29) clinical trial were presented during the Presidential Symposium of the European Society for Medical Oncology Congress in Berlin

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Dr. Lesley Seymour appointed 2025 CAHS Fellow

Dr. Lesley Seymour appointed 2025 CAHS Fellow

Congratulations to Dr. Lesley Seymour, CCTG’s IND Program Director and Deputy Director, on being named a Fellow in the Canadian Academy of Health Sciences (CAHS). Election to the Academy is one of the highest honours in the Canadian health sciences community, recognizing individuals for their exceptional contributions to advancing health research, policy, and care.

"I am honoured to be appointed as a CAHS Fellow and delighted that the contributions of Canadian Cancer Trials Group faculty and investigators have been recognized," says Dr. Seymour.

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