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Clinical Trials

The Canadian Cancer Trials Group (CCTG) supports national and international multicentre phase I-III cancer clinical research trials aimed at improving the survival and quality of life of cancer patients across all cancer types. The scientific agenda for the group is developed by clinical researchers across Canada and beyond, includes trials of new cancer agents, novel radiation and surgical techniques, as well as interventions to improve patient quality of life.

If you are a CCTG member and need to access the full trials pages please click here.

The links below will take you to pages that list all the current CCTG trials with a brief description. If you are interested in volunteering for a trial we suggest that you discuss the opportunity with your care team.

If you are a patient or caregiver and are looking for other information about clinical trials a complete listing of clinical trials being conducted in Canada, including the locations where they are being conducted, can be found here: Canadian Cancer Trials.  And if you are interested in learning about participating in a clinical trial more information can be found here: www.itstartswithme.ca

 

How can I participate in a clinical trial

 

How can I participate in a clinical trial

DYNAMIC-III (CO.29) clinical trial were presented during the Presidential Symposium of the European Society for Medical Oncology Congress in Berlin

Trial results show that a blood test can guide treatment decisions in advanced colon cancer

Results from the primary analysis of the ctDNA-negative cohort from the international DYNAMIC-III (CO.29) clinical trial were presented during the Presidential Symposium of the European Society for Medical Oncology Congress in Berlin

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Dr. Lesley Seymour appointed 2025 CAHS Fellow

Dr. Lesley Seymour appointed 2025 CAHS Fellow

Congratulations to Dr. Lesley Seymour, CCTG’s IND Program Director and Deputy Director, on being named a Fellow in the Canadian Academy of Health Sciences (CAHS). Election to the Academy is one of the highest honours in the Canadian health sciences community, recognizing individuals for their exceptional contributions to advancing health research, policy, and care.

"I am honoured to be appointed as a CAHS Fellow and delighted that the contributions of Canadian Cancer Trials Group faculty and investigators have been recognized," says Dr. Seymour.

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CCTG SR.8 HARMONY sarcoma trial awarded CIHR funding

CCTG SR8 HARMONY sarcoma trial awarded CIHR funding

The CCTG SR.8 (HARMONY) clinical trial has been awarded almost 1.5 million through the CIHR spring Project Grant Program. A phase III study that addresses a significant unmet need in the treatment of high-risk soft-tissue sarcoma (STS).

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The BR38 trial testing targeted radiotherapy added to immunotherapy to improve outcomes for lung cancer patients.

The BR38 trial is testing targeted radiotherapy added to immunotherapy to improve outcomes for lung cancer patients

The recently opened BR38 clinical trial is exploring whether adding stereotactic body radiotherapy (SBRT) to the current treatment of immunotherapy (with or without chemotherapy) can improve outcomes for patients with metastatic non-small cell lung cancer (NSCLC) and limited disease progression (oligoprogression).

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