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CCTG Connection



Published:
Category: Trials
Closed to accrual: IND.238 sub-study A

IND.238 sub-study A is a phase II study of Durvalumab in patients who discontinued prior checkpoint therapy due to immune related toxicity has closed to accrual. Treatment and follow up for sub-study A patients will continue as per protocol. 

The purpose of this study is to find out what effects being treated with durvalumab has on cancer. The researchers doing this study also want to evaluate if prednisone (a type of steroid), when given together with durvalumab, can reduce any side effects.

 

 
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Published:
Category: Trials
Trial closure: MAC25

MAC25 (NRG-BR004): A Randomized, Double-Blind, Phase III Trial of Taxane/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer trial has closed.

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Published:
Category: Group updates
American Association for Cancer Research Scientist-Survivor Program

Call for Applications: American Association for Cancer Research Scientist↔Survivor Program® 

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Published:
Category: Group updates
IT update New login screen for users

CCTG is upgrading the login platform to Auth0 by Okta for a more secure and seamless login experience. The new login screen is designed to be simple and user-friendly, allowing users to log in using existing credentials. This change ensures faster, more reliable access to your account with fewer sign ins, while keeping your data safe.

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Published:
Category: Publications
Publications: General Review
Hematology Cohort study - Outcomes following exposure to drug interactions with ibrutinib in patients with chronic lymphocytic leukaemia and MA20 Sub study - Prognostic and predictive capacity of tumor infiltrating lymphocytes in the MA.20 regional node radiotherapy trial Read More

Published:
Category: Publications
Publication: Primary ICC1COVID-19 in Cancer Patients Study
ICC1 primary publication: Risk Factors for COVID-19–Related Hospitalization and Death in Patients With Cancer. The National Cancer Institute COVID-19 in Cancer Patients Study (NCCAPS) Read More

Published:
Category: Publications
Publication: Primary NEC3

NEC3 (Alliance A021202) was a randomized phase II trial of pazopanib versus placebo in patients with advanced extrapancreatic neuroendocrine tumors

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Published:
Category: Publications
Publication: Statistical
Joint Analysis of Longitudinal Proportional Measurements and Survival Times Based on Generalized Mean-Variance Mixed Model and Cox Proportional Hazards Model
 
In cancer clinical trials and other types of medical studies, longitudinal data are often observed in conjunction with survival data.
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