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Group newsletter: CCTG Connection

Archived Bulletins

December 11, 2019

About 32 percent of older, sicker patients enrolled on a leukemia clinical trial experienced serious side effects from a treatment that combined a chemotherapy and an immunotherapy drug, leading investigators to pause the trial and the U.S. Food and Drug Administration to eventually pull the combination from the current study. The study was presented by Dr. Annette Hay at the 61st American Society of Hematology (ASH) Annual Meeting the world’s largest conference devoted to blood diseases and blood cancers like lymphoma, the findings serve as both triumph and warning.

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Published: December 11, 2019
Category: News

Next year is almost here and in 2020 CCTG will be marking our 40th anniversary! We would like to recognize this milestone and the hard work of our clinical trials network across Canada at an anniversary celebration during the 2020 CCTG Spring Meeting.

Save the Date - evening of May 1, 2020

  • CCTG 40th Anniversary Celebration
  • Friday May 1, 2020 at the Spring Meeting

Event details to follow in the New Year - make sure to save the date and celebrate 40 years of clinical trial excellence.

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Published: December 11, 2019
Category: Publications
Publication - CL3

A Genetic, Risk-Stratified Randomized Phase II Study of Four Fludarabine/Antibody Combinations For Patients with Symptomatic Previously Untreated Chronic Lymphocytic Leukemia. This randomized phase II trial studies how well fludarabine (fludarabine phosphate) and rituximab with or without lenalidomide or cyclophosphamide work in treating patients with symptomatic chronic lymphocytic leukemia.

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November 27, 2019

Published: November 27, 2019
Category: Trials
Trial Closure: IND208, IND221, IND229, ES2

The following CCTG trials have been permanently closed.

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Published: November 27, 2019
Category: Group updates

We are coming up to a big holiday for American families. Please expect closure of U.S. Operations offices and laboratories on Thursday, November 28nd for the U.S. Thanksgiving. If you are planning to ship specimens to the U.S., please plan accordingly. Also remember that many of our U.S. collegues take additional holidays for an extra long weekend.

Happy Thanksgiviing to our U.S friends!

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Published: November 27, 2019
Category: News
 Dr. Kuruvilla and Dr. Crump about CCTG LY17

CCTG LY17 is a A Multi-stage Randomized Phase II Study of Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma. The trial is looking to determine the overall response rate (complete and partial response) to novel combination therapy in patients with relapsed and refractory aggressive B cell lymphoma. Dr. Kuruvilla and Dr. Crump stress the importance of this trial, collaboration within CCTG, and the overall benefit of cancer clinical trials. (NCT02436707)

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Published: November 27, 2019
Category: News
Congratulations to Dr. Sarit Assouline

CCTG is pleased to announce that the fall recipient of the Frances A. Shepherd Award is Dr. Assouline Division of Hematology McGill University, Jewish General Hospital Montreal, Quebec and the CCTG Hematologic Disease Site Chair

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Published: November 27, 2019
Category: Publications
Publication - IND229 and IND222

IND229 Publication: A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2 - Positive Metastatic Breast Cancer

IND222 Publication: A phase I study of vistusertib (dual mTORC1/2 inhibitor) in patients with previously treated glioblastoma multiforme: A CCTG study.

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