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CCTG Connection



Published:
Category: Publications
Publication: substudy MA32
Exploration of body mass index and circulating metabolic factors as predictors of metformin benefit in the Canadian Cancer Trials Group MA.32 Read More

Published:
Category: Trials
CO.21 IMPACT:
The Canadian Cancer Society recently announced a $525,000 Challenge Grant award for a CO.21 implementation study. The Challenge Grants program supports cancer research projects that are focused on solving a cancer related problem.challenge gran 42 new research projects. The landmark CCTG CO.21 clinical trial demonstrated that a lifestyle intervention reduced the risk of disease recurrence by 28% and improved survival by 37%. This groundbreaking trial revolutionized how exercise interventions are viewed as a necessary treatment option. Read More

Published:
Category: Trials
EN12 RAINBO-ORANGE successful CIHR Project Grant funding
The EN12 RAINBO-ORANGE clinical trial was awarded $1,575,898 through the CIHR Project Grant to investigate if surgery followed by radiotherapy and a type of oral endocrine therapy called progestins will lead to similar cancer control as surgery followed by radiotherapy and chemotherapy in patients with NSMP, estrogen receptor-positive endometrial cancer (EC). Read More

Published:
Category: Trials
Dr. Michael Ong the PR26 TRIPLE-SWITCH study chair

In this video interview by UroToday, Dr. Michael Ong the PR26 TRIPLE-SWITCH study chair, describes the trial design, a phase 3 study randomizing patients with metastatic hormone-sensitive prostate cancer and PSA of 0.2 or above at six to twelve months of ADT plus any ARPI to either continue doublet therapy or add six cycles of docetaxel. The primary endpoint is overall survival; sample size is 830 patients.

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Published:
Category: Group updates
New Investigator Clinical Trials Course Celebrates it's 10th Anniversary!

August 19-21, 2026 at the Donald Gordon Hotel & Conference Centre in Kingston, Ontario

The New Investigator Clinical Trials Course (NICTC) is fast approaching! CCTG is welcoming nearly 60 young investigators from across Canada to a 2.5 day educational program. Now celebrating its 10th Anniversary this long-standing event has been training Canadian clinical investigators in the conduct of cancer clinical trials and provides a comprehensive introduction to the principles and practice of clinical trials within the Canadian research environment.

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Published:
Category: Group updates
Dr. Michael Munger
On behalf of the CCTG Gastrointestinal Committee please help us congratulate Dr. Michael Munger who recently enrolled his first patient to a GI study. 
 
Dr. Michael Munger is a Hematologist and Medical Oncologist at CHU de Québec–Université Laval. He completed his residency training in Hematology and Medical Oncology at Université Laval, followed by a fellowship in hematologic cytogenetics at Avicenne Hospital and Saint-Antoine Hospital in Paris, France. He serves as Medical Director of the Cytogenetics Laboratory at CHU de Québec.
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Published:
Category: Publications
Publication: CX5 exploritory analysis

Correlation of pelvic magnetic resonance imaging with diagnostic loop electrosurgical excision procedure/cone biopsy and hysterectomy pathology: an exploratory analysis of the CX.5/SHAPE trial

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Published:
Category: Publications
Publication: PA6 secondary analysis
Impact of Tumor Genomic Profile on Adjuvant Chemotherapy Efficacy in Resected Pancreatic Adenocarcinoma: Results From the PRODIGE-24/CCTG PA6 Study
 
Modified fluorouracil, leucovorin, irinotecan, and oxaliplatin (mFOLFIRINOX/mFFX) is the standard adjuvant chemotherapy for resected pancreatic ductal adenocarcinoma (PDAC), offering survival benefits over gemcitabine (GEM). However, the contribution of molecular biomarkers to treatment selection remains unclear.
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