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Breast Clinical Trials

A breast cancer clinical trial - MAC27
Trial Code: MAC27 | NCT04457596
Disease Site: Breast Clinical Trials

What is the purpose of this study?

The purpose of this study is to find out if the combination of a new drug and a commonly used drug is better than the commonly used drug alone at preventing this type of breast cancer from returning.

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A breast cancer clinical trial - MAC28
Trial Code: MAC.28 ǀ NCT04852887
Disease Site: Breast Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the usual treatment of breast radiation and hormonal drugs after lumpectomy to using hormonal drugs alone for 50 to 70 year old people with low risk breast cancer. The removal of breast radiation from the usual treatment may have no effect on whether your cancer returns, and it could also reduce side effects.

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A breast cancer clinical study - MAC26
Trial Code: MAC.26 ǀ NCT03598257
Disease Site: Breast Clinical Trials

What is the purpose of this study?

The purpose of this study is to find out if a new drug helps prevent your inflammatory breast cancer from returning when given with radiotherapy.

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Gastro-Intestinal Clinical Trials

A pancreatic cyst clinical trial - PAC4
Trial Code: PAC.4 ǀ NCT04239573
Disease Site: Gastro-Intestinal Clinical Trials

What is the purpose of this study?

The purpose of this study is to determine which approach, less frequent or more frequent monitoring, will lead to better outcomes for patients with pancreatic cysts.

Why is this study important?

Currently, the effectiveness of any pancreatic cyst monitoring strategy is unknown. Patients and physicians are eager to learn which strategy is better for this very common condition.

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A gastroesophageal clinical trial - GA4
Trial Code: GA.4 ǀ NCT06043427
Disease Site: Gastro-Intestinal Clinical Trials

What is the purpose of this study?

The purpose of this study is to find out what effects adding a new drug to the standard treatment has on you and your gastroesophageal cancer compared to the standard treatment given alone.

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A colon cancer study - CRC10
Trial Code: CRC.10 ǀ NCT 05174169
Disease Site: Gastro-Intestinal Clinical Trials

What is the purpose of this study?

The purpose of this study is to test if we can determine what kind of chemotherapy to offer patients based on whether or not circulating tumour DNA (ctDNA) is found in a blood test taken after surgery for colon cancer.

Why is this study important?

Using ctDNA testing to determine what kind of chemotherapy to use is a new approach. This approach seems promising, but it is not clear if it can offer better results than standard treatment.

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A neuroendocrine cancer clinical trial - NE1
Trial Code: CCTG NE.1 (NET RETREAT) ǀ NCT05773274
Disease Site: Gastro-Intestinal Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare a retreatment with Peptide Receptor Radionuclide Therapy (PRRT) to the standard treatment for your neuroendocrine cancer.

Why is this study important?

The drug being studied is a new type of drug approved for the treatment of neuroendocrine tumours (NETs). The new drug has been shown to shrink tumours in many people and seems promising, but it is not clear if receiving this drug again can offer better results than standard treatment.

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Genito-Urinary Clinical Trials

A prostate cancer clinical trial - PR24
Trial Code: PR.24 ǀ NCT06235697
Disease Site: Genito-Urinary Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the effects on you and your prostate cancer of getting a higher dose of radiation therapy given over a shorter period of time compared to the current way radiation therapy is used to treat prostate cancer.

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A metastatic urothelial cancer clinical trial - BLC5
Trial Code: BLC5 ǀ NCT05092958
Disease Site: Genito-Urinary Clinical Trials

What is the purpose of this study?

The purpose of this study is to see if adding a new drug to other drugs which are commonly used to treat metastatic urothelial cancer is better than the commonly used drugs alone.

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Gynecology Clinical Trials

A gynecological cancer clinical trial - EN10
Trial Code: EN10 | NCT05640999
Disease Site: Gynecology Clinical Trials

What is the purpose of this study?

The purpose of this study is to identify people who may not require treatment after surgery or may require less treatment after surgery because their cancer is at such a low risk of coming back based on the specific tumour features found by the laboratory testing and the extent of tumour spread. Receiving no treatment or less treatment can result in no or fewer side effects (fatigue, hair loss, bowel and bladder irritation).

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An endometrial cancer study - EN11
Trial Code: CCTG EN.11 ǀ NCT05255653
Disease Site: Gynecology Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the effects on you and your endometrial cancer of a new drug in combination with radiation therapy compared to the current standard treatment of radiation therapy alone.

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Head and Neck Clinical Trials

A head and neck cancer clinical trial - HN11
Trial Code: HN11 ǀ NCT05451004
Disease Site: Head and Neck Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the effects on you and your oropharyngeal cancer of radiotherapy to your neck guided by lymph node mapping (lymphatic mapping) using a special X-ray called Single Photon Emission Computed Tomography (SPECT-CT) compared to the current standard treatment where radiotherapy is given to both sides of the neck.

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Hematologic Clinical Trials

A multiple myeloma clinical trial - MY13
Trial Code: MY.13 ǀ NCT06182774
Disease Site: Hematologic Clinical Trials

What is the purpose of this study?

One of the treatments for multiple myeloma is with three medicines, all continued indefinitely until they stop working, or side effects happen. Two are tablets, and the third is an injection. In this study, we are testing if the injection can be stopped after around 18 months of treatment with no change to how your multiple myeloma is being controlled.

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A hematology clinical trial - HD12
Trial Code: HD12 │ NCT04685616
Disease Site: Hematologic Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the usual treatment for your Hodgkin lymphoma, which is a standard combination of four drugs, versus the standard combination with one drug of the combination replaced with a new drug that we hope will be more effective and cause you fewer side effects.

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A hematology clinical trial - CLC3
Trial Code: CLC3 ǀ NCT04269902
Disease Site: Hematologic Clinical Trials

What is the purpose of this study?

The purpose of this trial is to find out if people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) will live longer and have a better quality of life if they start treatment earlier. Some people do not have major symptoms when they are diagnosed with CLL or SLL. Treatment is often started when they show symptoms such as fever, anemia, or night sweats. Studies have shown that early treatment using older chemotherapy drugs doesn’t improve outcomes compared to later treatment.

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Lung Clinical Trials

A small cell lung cancer clinical trial - BRC8
Trial Code: BRC.8 ǀ NCT04155034
Disease Site: Lung Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the use of magnetic resonance imaging (MRI) surveillance combined with prophylactic cranial irradiation (PCI) to MRI surveillance alone in treating your lung cancer that can sometimes spread to the brain.

Why is this study important?

MRI scans are used to monitor the possible spread of the cancer with an MRI machine over time. PCI is radiation therapy that is delivered to the brain in hopes of preventing spread of cancer into the brain.

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Melanoma Clinical Trials

A melanoma clinical trial - MEC6
Trial Code: MEC6 | NCT05111574
Disease Site: Melanoma Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the effects on you and your mucosal melanoma of a new drug with the usual treatment compared to a placebo with the usual treatment.

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Sarcoma Clinical Trials

A sarcoma study - SR7
Trial Code: SR.7 | NCT04031677
Disease Site: Sarcoma Clinical Trials

What is the purpose of this study?

The purpose of this study is to compare the effects of receiving chemotherapy before surgery on you and your sarcoma compared to surgery alone.

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Symptom Control Clinical Trials

A supportive care clinical trial - SC28
Trial Code: SC.28 ǀ NCT05470010
Disease Site: Symptom Control Clinical Trials

What is the purpose of this study?

The purpose of this study is to test if a mindfulness program (Mindfulness Based Cancer Survivorship (MBCS) Journey) delivered through a mobile smartphone application (Am Mindfulness) can reduce ongoing psychosocial symptoms such as stress, anxiety, depression, fatigue, and fear of cancer recurrence or progression that are often experienced by survivors.

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