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CCTG Connection



Published:
Category: Publications
Publication: EN10 EN11  Barriers to Implementation

Endometrial Carcinoma Molecular Classification and Barriers to Implementation, Possible Solutions, and the Implications for Ongoing Clinical Trials. 

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Published:
Category: Publications
Publication: IND227 updated analysis
Abstract IND.227 oral presentation at the World Conference on Lung Cancer in Barcelona, Spain, on 8 September, 2025. Subsequently published in the Journal of Thoracic Oncology.
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Published:
Category: Publications
Publication: MA38 primary
MA38 primary publication Continuous versus Standard Palbociclib Treatment and Molecular Profiling of Solid Tissues and Liquid Biopsies in the CCTG MA.38 Trial in Advanced Breast Cancer.
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Published:
Category: Publications
QoL Substudy GA2
The INTEGRATE trials evaluated regorafenib in advanced gastric and esophagogastric junction cancer (AGOC), a poor prognosis population. In INTEGRATE 1 (I1, phase 2), regorafenib improved progression-free survival (PFS) without a clear excess decline in health-related quality of life (HRQoL). INTEGRATE 2a (I2a, phase 3) demonstrated an overall survival (OS) benefit, alone and in a pre-specified pooled analysis with I1.
 
Martin AJ, Soon YY, Sjoquist KM, Pavlakis N, Goldstein D, Shitara K, Simes JR.
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Published:
Category: Publications
Publication: Secondary analysis IND223, IND232 and IND234
Secondary analysis publication using data from IND223, IND232 and IND234.
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Published:
Category: Publications
Publication: Pooled Analysis BR34, CO26, IND226 and PA7

Effects of serotonergic drugs on immune checkpoint inhibitor response: a pooled analysis of individual patient data from four Canadian Cancer Trials Group (CCTG) trials BR34, CO26, I226 and PA7

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Published:
Category: Publications
Publication: PR19 analysis of initial arms

A randomized Phase II trial of High Dose-Rate (HDR) and Low Dose-Rate (LDR) brachytherapy as monotherapy in localized prostate cancer: analysis of initial arms of Canadian cancer trials group PR19

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Published:
Category: Publications
Publication: BLC4 secondary analysis
CCTG BLC4 (SWOG S1605) Urine Tumor DNA to Stratify the Risk of Recurrence
 
This study demonstrates that urine tumor DNA profiling can be used to stratify the risk of recurrence in patients after treatment with atezolizumab for bacillus Calmette-Guérin–unresponsive non–muscle-invasi
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