Wednesday, May 21, 2025 The ASCO 2025 Annual Meeting, is fast approaching and will be held from May 30 to June 3 in Chicago, Illinois -- This year the theme is of "Driving Knowledge to Action: Building a Better Future". This meeting will feature many CCTG trials and research so please see the list below to ensure you do not miss the oral presentations or poster presentations, showcasing the latest in CCTG research and clinical trial results. BREASTCCTG IND.241IND.241: A Canadian Cancer Trials Group liquid-biopsy informed platform trial to evaluate treatment in CDK4/6-inhibitor resistant ER+/HER2- metastatic breast.Abstract #: TPS1121Session Type: Poster SessionSession Title: Breast Cancer – MetastaticTrack: Breast CancerSubtrack: HER-2-PositiveCitation: Authors: David Cescon, Moira Rushton, Nathalie LeVasseur, Michelle Nadler, Daniel Rayson, Brooke Wilson, Sara Taylor, Rossanna Pezo, Arif Ali Awan, Vikaash Kumar, Jen Melvin, John Hilton, Stephen Chia, Philippe Bedard, Spencer Finn, Wei Tu, Courtney Coschi, Philippe Jamme, Elia Aguado-Fraile, Lesley SeymourAbstract link: https://meetings.asco.org/abstracts-presentations/252192 CCTG MA.37/ ABCSG-42/AFT-05/BIG-14-13/PrE0109 Treatment-related neutropenia as a predictor of response to adjuvant palbociclib in the PALLAS trial (ABCSG-42/AFT-05/BIG-14-13/PrE0109).Abstract #: 526Session Type: Poster SessionSession Title: Breast Cancer—Local/Regional/AdjuvantTrack: Breast CancerSubtrack: Adjuvant TherapyCitation: Authors: Kristina Fanucci, Amylou Dueck, Erica Mayer, Miguel Martin, Tufia Haddad, Nicholas Zdenkowski, Guenther Steger, Yelena Novik, Jennifer Suga, Julie Lemieux, Tiffany Traina, Sibylle Loibl, Meritxell Bellet, Antonio Wolff, Jana Machacek-Link, Eric Gauthier, Sara Scovil, Dominik Hlauschek, Michael Gnant, Angela DeMicheleAbstract link: https://meetings.asco.org/abstracts-presentations/244429CCTG MA.40 A double-blind placebo controlled randomized phase III trial of fulvestrant and ipatasertib as treatment for advanced HER-2 negative and estrogen receptor positive (ER+) breast cancer following progression on first line CDK 4/6 inhibitor and aromatase inhibitor: The CCTG/BCT MA.40/FINER study (NCT04650581).Abstract #: LBA1005Session Type: Oral Abstract SessionSession Title: Breast Cancer—MetastaticTrack: Breast CancerSubtrack: Hormone Receptor-PositiveCitation: Authors: Stephen Chia, Andrew Redfern, Jean-Pierre Ayoub, Haji Chalchal, Daniel Rayson, Moira Rushton, Christine Desbiens, Dhanusha Sabanathan, Jacques Raphael, Angela Chan, Jessica Singh, Christine Simmons, Nicholas Zdenkowski, Sheridan Wilson, Danielle Rodin, David Cescon, Frauke Schimmoller, Lisa Gallinaro, Bingshu Chen, Wendy ParulekarAbstract link: https://meetings.asco.org/abstracts-presentations/244383 CCTG MAC.13/BIG 2-06/NCCTG N063DLong-term outcomes of patients with HER2-positive invasive lobular carcinoma in the ALTTO trial (BIG 2-06/NCCTG N063D [Alliance])Abstract #: 542Session Type: Poster SessionSession Title: Breast Cancer – Local/Regional/AdjuvantTrack: Breast CancerSubtrack: Adjuvant TherapyCitation: Authors: Guilherme Nader Marta, Lieveke Ameye, Giuseppe Viale, Diogo Martins-Branco, Marianne Paesmans, Philippe Aftimos, Christine Desmedt, Anup Choudhury, Antonio Wolff, Ian Krop, Martine Piccart-Gebhart, Evandro de AzambujaAbstract link: https://meetings.asco.org/abstracts-presentations/244439CCTG MAC.20/Alliance A011401Association of lifestyle factors and pathological characteristics in patients with early breast cancer and overweight/obesity: Results from the Breast Cancer Weight Loss (BWEL) trial.Abstract #: 561Session Type: Poster SessionSession Title: Breast Cancer – Local/Regional/AdjuvantTrack: Breast CancerSubtrack: Biologic CorrelatesCitation: Authors: Caterina Sposetti, Karla Ballman, Linda McCall, Pamela Goodwin, Anna Weiss, Cynthia Thomson, Olwen Hahn, Dawn Hershman, Electra Paskett, Lori Minasian, Linda Nebeling, Erica Mayer, Judith Hopkins, Vanessa Bernstein, Vered Stearns, Julia White, Eric Winer, Ann Partridge, Lisa Carey, Jennifer LigibelAbstract link: https://meetings.asco.org/abstracts-presentations/245927 CCTG MAC.20/Alliance A011401 Intervention adherence, engagement and tool utilization in the breast cancer weight loss (BWEL) trial by race and ethnicity (Alliance A011401).Abstract #: 1586Session Type: Poster SessionSession Title: Care Delivery/Models of CareTrack: Care Delivery and Quality CareSubtrack: Disparities in CareCitation: Authors: Ashley Odai-Afotey, Linda McCall, Karla Ballman, Chao Cao, Pamela Goodwin, Vanessa Bernstein, Linda Delahanty, Dawn Hershman, Judith Hopkins, Erica Mayer, Electra Paskett, Patricia Spears, Vered Stearns, Anna Weiss, Julia White, Thomas Wadden, Eric Winer, Lisa Carey, Ann Partridge, Jennifer LigibelAbstract link: https://meetings.asco.org/abstracts-presentations/245405 CCTG MAC.28/NRG BR007 NRG-BR007: A phase III trial evaluating de-escalation of breast radiation (DEBRA) following breast-conserving surgery of stage 1, HR+, HER2-, RS ≤18 breast cancer.Abstract #: TPS625Session Type: Poster SessionSession Title: Breast Cancer—Local/Regional/AdjuvantTrack: Breast CancerSubtrack: Local-Regional TherapyCitation: Authors: Julia White, Reena Cecchini, Eleanor Harris, Eleftherios Mamounas, Jose Bazan, Daniel Stover, Patricia Ganz, Reshma Jagsi, Stewart Anderson, Carmen Bergom, Valérie Théberge, Mahmoud El-Tamer, Richard Zellars, Dean Shumway, Guang-Pei Chen, Thomas Julian, Norman WolmarkAbstract link: https://meetings.asco.org/abstracts-presentations/252167CCTG MAC.30/NRG BR009 A phase III trial evaluating addition of adjuvant chemotherapy to ovarian function suppression + endocrine therapy in premenopausal women with pN0-1, HR+/HER2- breast cancer (BC) and oncotype recurrence score (RS) ≤25 (OFSET): NRG-BR009.Abstract #: TPS615Session Type: Poster SessionSession Title: Breast Cancer—Local/Regional/AdjuvantTrack: Breast CancerSubtrack: Adjuvant TherapyCitation: Authors: Eleftherios Mamounas, Gong Tang, Shannon Puhalla, Sandra Swain, Patricia Ganz, Norah Henry, Reena Cecchini, Sonya Reid, Priya Rastogi, Charles Geyer Jr., Julia White, Amy Clark, Tufia Haddad, Gregory Vidal, Norman WolmarkAbstract link: https://meetings.asco.org/abstracts-presentations/252168GASTROINTESTINALCCTG CO.21A randomized phase III trial of the impact of a structured exercise program on disease-free survival (DFS) in stage 3 or high-risk stage 2 colon cancer: Canadian Cancer Trials Group (CCTG) CO.21 (CHALLENGE).Abstract #: LBA3510Session Type: Clinical Science SymposiumSession Title: Adjunctive Therapies in Colon Cancer: As Good as a Drug?Track: Gastrointestinal Cancer—Colorectal and AnalSubtrack: Colorectal Cancer–Local-Regional DiseaseCitation: Authors: Christopher Booth, Janette Vardy, Christopher O'Callaghan, Sharlene Gill, Christine Friedenreich, Rebecca Wong, Haryana Dhillon, Victoria Coyle, Neil Chua, Derek Jonker, Philip Beale, Kamal Haider, Patricia Tang, Tony Bonaventura, Ralph Wong, Howard Lim, Matthew Burge, Patti O'Brien, Dongsheng Tu, Kerry CourneyaAbstract link: https://meetings.asco.org/abstracts-presentations/244420 CCTG CO.29/AGITG CTDNA-08ctDNA-guided adjuvant chemotherapy escalation in stage III colon cancer: Primary analysis of the ctDNA-positive cohort from the randomized AGITG dynamic-III trial (intergroup study of AGITG and CCTG).Abstract #: 3503Session Type: Oral Abstract SessionSession Title: Gastrointestinal Cancer—Colorectal and AnalTrack: Gastrointestinal Cancer— Colorectal and Anal Subtrack: Colorectal Cancer–Local-Regional DiseaseCitation: Authors: Jeanne Tie, Yuxuan Wang, Jonathan Loree, Joshua Cohen, David Espinosa, Rachel Wong, Timothy Price, Niall Tebbutt, Margaret Lee, Matthew Burge, Samuel Harris, Belinda Lee, James Lynam, Christopher O'Callaghan, Daniel Breadner, Chetan Bettegowda, Nickolas Papadopoulos, Kenneth Kinzler, Bert Vogelstein, Peter GibbsAbstract link: https://meetings.asco.org/abstracts-presentations/244719 CCTG CRC.5//CALGB/SWOG 80405Long non-coding RNA (lncRNA) SNHG11 as a prognostic and predictive biomarker in metastatic colorectal cancer (mCRC): Insights from CALGB (Alliance)/SWOG 80405.Abstract #: 3128Session Type: PosterSession Title: Developmental Therapeutics—Molecularly Targeted Agents and Tumor BiologyTrack: Developmental Therapeutics—Molecularly Targeted Agents and Tumor BiologySubtrack: Tissue-Based BiomarkersCitation: Authors: Michela Bartolini, Francesca Battaglin, Joshua Millstein, Fang-Shu Ou, Shivani Soni, Pooja Mittal, Sandra Algaze, Karam Ashouri, Lesly Torres-Gonzalez, Unnati Shah, Priya Jayachandran, Wu Zhang, Alan Venook, Federico Innocenti, Alberto Puccini, Heinz-Josef LenzAbstract link: https://meetings.asco.org/abstracts-presentations/244175 CCTG CRC.5/CALGB/SWOG 80405Small nucleolar RNAs (snoRNAs) expression and effects on patient (pt) outcomes in metastatic colorectal cancer (mCRC): Data from CALGB (Alliance)/SWOG 80405.Abstract #: 3145Session Type: PosterSession Title: Developmental Therapeutics—Molecularly Targeted Agents and Tumor BiologyTrack: Developmental Therapeutics—Molecularly Targeted Agents and Tumor BiologySubtrack: Tissue-Based BiomarkersCitation: Authors: Francesca Battaglin, Joshua Millstein, Michela Bartolini, Karam Ashouri, Shivani Soni, Sandra Algaze, Pooja Mittal, Lesly Torres-Gonzalez, Priya Jayachandran, Unnati Shah, Wu Zhang, Federico Innocenti, Fang-Shu Ou, Alan Venook, Heinz-Josef LenzAbstract link: https://meetings.asco.org/abstracts-presentations/244176 CCTG CRC.6/CALGB/SWOG 80702Association between empirical dietary inflammatory pattern (EDIP) and survival in patients with stage III colon cancer: Findings from CALGB/SWOG 80702 (Alliance).Abstract #: LBA3509Session Type: Clinical Science SymposiumSession Title: Adjunctive Therapies in Colon Cancer: As Good as a Drug?Track: Gastrointestinal Cancer—Colorectal and AnalSubtrack: Epidemiology/OutcomesCitation: Authors: Sara Char, Qian Shi, Tyler Zemla, Chao Ma, En Cheng, Priya Kumthekar, Katherine Guthrie, Felix Couture, J. Kuebler, Pankaj Kumar, Benjamin Tan, Smitha Krishnamurthi, Brian Wolpin, Francois Geoffroy, Fred Tabung, Anthony Shields, Eileen O'Reilly, Jeffrey Meyerhardt, Chen Yuan, Kimmie NgAbstract link: https://meetings.asco.org/abstracts-presentations/244419 CCTG CRC.6/CALGB/SWOG 80702Sex differences in chemotherapy completion and adverse events among patients with colon cancer (CALGB/SWOG 80702) (Alliance).Abstract #: 3624Session Type: Poster SessionSession Title: Gastrointestinal Cancer—Colorectal and AnalTrack: Gastrointestinal Cancer—Colorectal and AnalSubtrack: Epidemiology/OutcomesCitation: Authors: En Cheng, Qian Shi, Anthony Shields, Chaoyuan Kuang, Ardaman Shergill, Chao Ma, Katherine Guthrie, Felix Couture, J. Kuebler, Pankaj Kumar, Benjamin Tan, Smitha Krishnamurthi, Kimmie Ng, Eileen O'Reilly, Justin Brown, Philip Philip, Jeffrey MeyerhardtAbstract link: https://meetings.asco.org/abstracts-presentations/244843 CCTG CRC.10/NRG GI008Colon adjuvant chemotherapy based on evaluation of residual disease (CIRCULATE-NORTH AMERICA): NRG-GI008.Abstract #: TPS3644Session Type: Poster SessionSession Title: Gastrointestinal Cancer—Colorectal and AnalTrack: Gastrointestinal Cancer—Colorectal and AnalSubtrack: Colorectal Cancer–Local-Regional DiseaseCitation: Authors: Arvind Dasari, Guan Yu, Scott Kopetz, Shannon Puhalla, Peter Lucas, Ibrahim Halil Sahin, Dustin Deming, Philip Philip, Theodore Hong, Yesenia Rojas-Khalil, Jonathan Loree, Norman Wolmark, Greg Yothers, Thomas George, Christopher LieuAbstract link: https://meetings.asco.org/abstracts-presentations/252298 CCTG NE.2/AGITG AG0219NETAustralasian Gastro-Intestinal Trials Group (AGITG) STOPNET: A randomized study of cessation of somatostatin analogues (SSA) after peptide receptor radionuclide therapy (PRRT) in mid, hind-gut, and pancreatic neuroendocrine tumours.Abstract #: TPS4224Session Type: Poster SessionSession Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and HepatobiliaryTrack: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and HepatobiliarySubtrack: Neuroendocrine/CarcinoidCitation: Authors: Matthew Burge, David Wyld, David Pattison, Sandra Bahamad, Sarah Hayes, Julia Kuszewski, Lorraine Chantrill, Timothy Price, Hui-Li Wong, David Chan, Piyush Grover, Michael Michael, Derrick Siu, Christine Bishop, Daniel Barker, Rachel Goodwin, Christopher O'Callaghan, Jonathan Loree, W MakAbstract link: https://meetings.asco.org/abstracts-presentations/252346 CCTG PA.7Concurrent mutations in DNA damage repair genes BRCA1, POLE, ATM and FANCA to predict overall and progression-free survival for patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC) treated with chemotherapy in combination with dual checkpoint inhibition in the CCTG randomized PA.7 trial.Abstract #: 4178Session Type: Poster SessionSession Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and HepatobiliaryTrack: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and HepatobiliarySubtrack: Pancreatic Cancer - Advanced/Metastatic DiseaseCitation: Authors: Daniel Renouf, James Topham, Jonathan Loree, Dongsheng Tu, David Schaeffer, Jennifer Knox, Petr Kavan, Derek Jonker, Stephen Welch, Felix Couture, Frederic Lemay, Mustapha Tehfe, Mohammed Harb, Nathalie Aucoin, Yoo-Joung Ko, Patricia Tang, Pan Du, Shidong Jia, Sharlene Gill, Christopher O'CallaghanAbstract link: https://meetings.asco.org/abstracts-presentations/249858 GENITOURINARY CCTG IND.234CSubstudy C of the Canadian cancer trials group (CCTG) IND.234: PC_BETS (Prostate Cancer Biomarker Enrichment and Treatment Selection)—A phase II study of darolutamide (DARO) selected by androgen-receptor (AR) circulating tumor DNA (ctDNA) in patients (PTS) with metastatic castration-resistant prostate cancer (mCRPC) after prior AR pathway inhibitors (ARPIs).Abstract #: 5056Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer– Advanced/Castrate-ResistantCitation: Authors: Michael Ong, Kim Chi, Sebastien Hotte, Eric Winquist, Fred Saad, Cristiano Ferrario, Robyn Macfarlane, Michael Kolinsky, Aaron Hansen, Muhammad Salim, Christian Kollmannsberger, Aly-Khan Lalani, Lesley Seymour, Som Mukherjee, Edmond Kwan, Max Sherry, Dongsheng Tu, Mariam Jafri, Alexander Wyatt, Wei TuAbstract link: https://meetings.asco.org/abstracts-presentations/246341 CCTG IND.234FSubstudy F of the Canadian Cancer Trials Group (CCTG) IND.234: PC_BETS (Prostate Cancer Biomarker Enrichment and Treatment Selection)—A biomarker-selected phase II study of durvalumab and tremelilumab (DT) in patients (pts) with previously treated metastatic castration-resistant prostate cancer (mCRPC) resistant to AR pathway inhibitors (ARPI).Abstract #: 5057Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer– Advanced/Castrate-ResistantCitation: Authors: Sebastien Hotte, Daniel Khalaf, D. S. Ernst, Cristiano Ferrario, Michael Ong, Michael Kolinsky, Muhammad Salim, Lucia Nappi, Som Mukherjee, Eric Winquist, April Rose, Kim Chi, Kylea Potvin, Lesley Seymour, Edmond Kwan, Martin Smoragiewicz, Hamid Ghaedi, Wei Tu, Mariam Jafri, Alexander WyattAbstract link: https://meetings.asco.org/abstracts-presentations/246342 CCTG IND.234GSubstudy G of the Canadian cancer trials group (CCTG) IND.234: PC_BETS (V)—A circulating tumor DNA (ctDNA)–directed phase II study of carboplatin in patients (Pts) with previously treated metastatic castration-resistant prostate cancer (mCRPC).Abstract #: 5058Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer– Advanced/Castrate-ResistantCitation: Authors: April Rose, Sebastien Hotte, Eric Winquist, Robyn Macfarlane, Kim Chi, Michael Kolinsky, Muhammad Salim, Di Maria Jiang, Michael Ong, Cristiano Ferrario, Aly-Khan Lalani, D. S. Ernst, Parvaneh Fallah, Matti Annala, Edmond Kwan, Francisco Vera Badillo, Lesley Seymour, Wei Tu, Alexander Wyatt, Mariam JafriAbstract link: https://meetings.asco.org/abstracts-presentations/246343 CCTG IND.234/223Canadian Cancer Trials Group (CCTG) IND.234/223: PC_BETS (Prostate Cancer Biomarker Enrichment and Treatment Selection)–A molecularly selected cooperative group platform study.Abstract #: 5066Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer– Advanced/Castrate-ResistantCitation: Authors: Alexander Wyatt, Kim Chi, Sebastien Hotte, Cristiano Ferrario, Eric Winquist, Michael Ong, Michael Kolinsky, Robyn Macfarlane, Fred Saad, Aaron Hansen, Aly-Khan Lalani, Daniel Khalaf, April Rose, D. S. Ernst, Christina Canil, James Hutchenreuther, Lesley Seymour, Wei Tu, Mariam Jafri, Hamid GhaediAbstract link: https://meetings.asco.org/abstracts-presentations/246359 CCTG PR.24Androgen suppression combined with elective nodal irradiation and dose escalated prostate treatment: A non-inferiority, phase III randomized controlled trial of stereotactic body radiation therapy versus brachytherapy boost in patients with unfavourable risk localized prostate cancer (ASCENDE-SBRT; CCTG PR24; NCT06235697)Abstract #: TPS5132Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer–Local-Regional DiseaseCitation: Authors: Andrew Loblaw, Rachel Glicksman, Joelle Helou, Winkle Kwan, Gerard Morton, Tamim Niazi, Melanie Davidson, M. N. Reaume, Alexander Wyatt, Constance Laroche-Lefebvre, Keyue Ding, Wendy ParulekarAbstract link: https://meetings.asco.org/abstracts-presentations/253058 CCTG PR.25A randomized phase III trial investigating platinum and taxane chemotherapy in metastatic castration resistant prostate cancer (mCRPC) patients with alterations in DNA damage response (DDR) genes (OPTION-DDR) CCTG-PR-25 NCT06439225.Abstract #: TPS5122Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer– Advanced/Castrate-ResistantCitation: Authors: Michael Kolinsky, Kim Chi, Sebastien Hotte, Michael Brundage, Michael Ong, David Boren, M. N. Reaume, Alexander Wyatt, Wendy Parulekar, Keyue Ding, Mariam JafriAbstract link: https://meetings.asco.org/abstracts-presentations/252393 CCTG PR.26TRIPLE-SWITCH (SWOG/CCTG-PR26): A randomized phase III clinical trial for the addition of docetaxel to androgen receptor pathway inhibitors in patients with metastatic castration sensitive prostate cancer (mCSPC) and suboptimal PSA response (NCT06592924).Abstract #: TPS5129Session Type: Poster SessionSession Title: Genitourinary Cancer—Prostate, Testicular, and PenileTrack: Genitourinary Cancer—Prostate, Testicular, and PenileSubtrack: Prostate Cancer– Advanced/Hormone-SensitiveCitation: Authors: Michael Ong, Alexandra Sokolova, Sebastien Hotte, Tanya Dorff, Kim Chi, Alexander Wyatt, Amir Goldkorn, Michael Kolinsky, Michael Brundage, Akunne Ndika, Seth Lerner, Wendy Parulekar, Keyue Ding, Mariam JafriAbstract link: https://meetings.asco.org/abstracts-presentations/252386 GYNECOLOGIC CANCERCCTG VU.2Stratification of vulvar squamous cell carcinoma (VSCC) by HPV and P53 status to guide excision: CCTG VU.2 STRIVE study (NCT06358469).Abstract #: TPS5637Session Type: Poster SessionSession Title: Gynecologic CancerTrack: Gynecologic CancerSubtrack: Other Gynecologic CancerCitation: Authors: Amy Jamieson, Jessica McAlpine, Lien Hoang, Mark Carey, Mary Kinloch, Eric Leung, Vanessa Samouëlian, Stephen Welch, Iwa Kong, Janice S. Kwon, Heather Tomalty, Dongsheng Tu, Wendy ParulekarAbstract link: https://meetings.asco.org/abstracts-presentations/253003 HEAD AND NECK CANCERCCTG HN.13A phase III randomized controlled trial comparing palliative stereotactic body radiotherapy vs. palliative standard radiotherapy in patients with advanced head and neck cancer (NCT06641791).Abstract #: TPS6118Session Type: Poster SessionSession Title: Head and Neck CancerTrack: Head and Neck CancerSubtrack: Local-Regional DiseaseCitation: Authors: Ian Poon, Irene Karam, Houda Bahig, Brock Debenham, Adam Mutsaers, Murali Rajaraman, Chiaojung Jillian Tsai, Lee Chin, Madette Galapin, Scott Bratman, Jolie Ringash, Ambika Parmar, Koren Smith, Sarah Radcliffe, Wei Tu, Wendy ParulekarAbstract link: https://meetings.asco.org/abstracts-presentations/252904 SUPPORTIVE CARECCTG SC.29A randomized phase III study comparing stereotactic body radiotherapy (SBRT) versus conventional palliative radiotherapy (CRT) for participants with painful non-spine bone metastases (NCT06391242).Abstract #: TPS12141Session Type: Poster SessionSession Title: Symptom Science and Palliative CareTrack: Symptom Science and Palliative CareSubtrack: Palliative Care and Symptom ManagementCitation: Authors: Arjun Sahgal, Tim Nguyen, Laura Masucci, Kristopher Dennis, Emma Dunne, Anand Swaminath, Isabelle Thibault, Chiaojung Jillian Tsai, Pejman Maralani, Michael Brundage, Marc Kerba, Joel Lefebvre, Wei Tu, Wendy ParulekarAbstract link: https://meetings.asco.org/abstracts-presentations/252931 LUNG/THORACIC ONCOLOGYCCTG BR.36A biomarker-directed, multi-center phase II/III study of ctDNA molecular response adaptive immuno-chemotherapy in patients with non-small cell lung cancer (BR.36).Abstract #: TPS8669Session Type: Poster SessionSession Title: Lung Cancer – Non-Small Cell MetastaticTrack: Lung CancerSubtrack: ImmunotherapiesCitation: Authors: Valsamo Anagnostou, Sara Moore, Penelope Bradbury, Cheryl Ho, Rosalyn Juergens, Adrian Sacher, Sofia Genta, Lacey Pitre, Michela Febbraro, Julie Brahmer, Egor Avrutin, Pierre-Olivier Gaudreau, Mark Sausen, Samik Upadhaya, Alicia Zhou, Keyue Ding, Janet DanceyAbstract link: https://meetings.asco.org/abstracts-presentations/252564