CCTG has opened the anticipated international brain cancer study CCTG CE9 (LUMOS2) - joining forces with the Australian Cooperative Trials Group for Neuro-Oncology (COGNO) to make enrollment accessible to Canadian patients.
Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma: The BATTMAN Trial
STRIDE (durvalumab + tremelimumab) with Lenvatinib vs STRIDE Alone in Patients with Unresectable Hepatocellular Carcinoma (SLIDE-HCC)
The CCTG ES3 NEEDS international esophageal cancer clinical trial is now opened in Canada. The study is investigating whether delaying surgery for patients with squamous cell carcinoma of the esophagus is as good as the current treatment.
Venetoclax and HMA-based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-mutated AML: A myeloMATCH Treatment Trial
Phase 2 Trial of ASTX727 and Venetoclax Compared with ASTX727, Venetoclax, and Enasidenib for Newly Diagnosed Older Adults with IDH2 Mutant AML - A myeloMATCH Substudy
Eradicating MRD in Patients with AML prior to Stem Cell Transplant (ERASE)
LUNA-2: LND101 in Unresectable Non-Small Cell Lung Cancer: A Randomized Phase II Trial
VIGOR: Vorasidenib as Maintenance Treatment after First-line Chemoradiotherapy in IDH-mutant Grade 2 or 3 Astrocytoma
RAINBO-ORANGE: Treatment of Endometrial Cancer Based On Molecular Features
If you are attending the CCTG Spring Meeting #CCTG2025 don't forget to drop by the open workshop and education session on engaging patient representatives in CCTG clinical trials. This accredited workshop takes place on Friday April 25, 10:30-12pm in the Seymour room at the Chelsea Hotel.
The Marathon of Hope Cancer Centres Network has reached a significant milestone with the publication of its first landmark paper in a major scientific journal. Published in the prestigious journal Cancer Cell, the paper highlights the Network’s history, objectives and key accomplishments to date, underscoring how this unprecedented national collaboration is working to transform precision oncology in Canada.
A phase II study of neoadjuvant opnurasib KRAS G12C inhibitor in patients with surgically resectable non-small cell lung cancer: A substudy of the IND.242 platform master protocol
The CCTG Patient Representative Committee (PRC) sends a heartfelt thank you to two key members who will be leaving us this month, Marie-Térèse Little and Carol Gordon. Their contributions have been transformative, and we are fortunate to have had their unwavering engagement and insight over the years. Their dedication will continue to inspire and elevate the work of the committee to improve cancer research for patients everywhere.
The CCTG Annual Spring Meeting is only 5 weeks away! If you have not registered or requested an Invitation, please do so now! Here are some things for you to keep in mind:
Meeting Information
All meeting information is available on the Spring Meeting Web Page and includes:
