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CCTG Connection



Published:
Category: Publications
Dr Janet Dancey, Director CCTG
A generalized single-index linear threshold model for identifying treatment-sensitive subsets based on multiple covariates and longitudinal measurements| AND | Unified estimation for Cox regression model with nonmonotone missing at random covariates. Read More

Published:
Category: Publications
Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial.
Manji A, Samson Y, Deyell RJ, Johnston DL, Lewis VA, Zorzi AP, Berman JN, Brodeur-Robb K, Morrison E, Kee L, Kumar S, Baruchel S, Whitlock JA, Morgenstern DA. Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial.
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Published:
Category: Trials
CCTG BLC5, a bladder cancer clinical trial is now open in Canada

CCTG BLC5 MAIN-CAV: Phase III Randomized Clinical Trial

The CCTG BLC5 MAIN-CAV international trial is now open in Canada testing the addition of a targeted anti-cancer drug to the usual immunotherapy treatment, in patients with metastatic urothelial cancer (mUC).This trial will test whether the addition of the anti-cancer drug, to the maintenance immunotherapy will or will not improve the patient’s overall survival.

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Published:
Category: Group updates
CCTG Patient Representatives are in high demand. Recently some of our committee members have had the opportunity to share their experiences and expertise at stakeholder events both nationally and internationally. Read More

Published:
Category: Group updates
CCTG is seeking a Senior Investigator

CCTG seeking an outstanding and visionary cancer trialist for the position of Senior Investigator (SI). Expertise in cancer clinical trial methods and conduct is required.

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Published:
Category: Trials
CCTG HN11 SELECT trial is now open

The CCTG HN11 SELECT study has now opened to accrual across Canada and sites in the US. The trial is a randomized, controlled, phase III clinical trial for patients with lateralized oropharyngeal carcinoma (OPC) and will compare the effectiveness of standard radiotherapy to personalized radiotherapy guided by the lymphatic mapping technique using SPECT-CT.

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Published:
Category: Trials
Closed to Accrual: CEC27
The CEC7 Study a Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared with Fractionated SRS (FSRS) for Resected Metastatic Brain Disease has closed to further accrual after meeting its accrual target.
 
This phase III trial studies how well single fraction stereotactic radiosurgery works compared with fractionated stereotactic radiosurgery in treating patients with cancer that has spread to the brain from other parts of the body and has been removed by surgery.
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Published:
Category: Group updates
Canadian Thanksgiving Monday October 10

A reminder that this weekend is Canadian Thanksgiving and the CCTG Central Offices will be closed on Monday, October 10th. All of the online applications will still be available and regular office hours resume on Tuesday October 11th at 8:30am. Happy Turkey Day!

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