CCTG has opened the anticipated international brain cancer study CCTG CE9 (LUMOS2) - joining forces with the Australian Cooperative Trials Group for Neuro-Oncology (COGNO) to make enrollment accessible to Canadian patients.
Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma: The BATTMAN Trial
The CCTG ES3 NEEDS international esophageal cancer clinical trial is now opened in Canada. The study is investigating whether delaying surgery for patients with squamous cell carcinoma of the esophagus is as good as the current treatment.
Venetoclax and HMA-based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-mutated AML: A myeloMATCH Treatment Trial
Phase 2 Trial of ASTX727 and Venetoclax Compared with ASTX727, Venetoclax, and Enasidenib for Newly Diagnosed Older Adults with IDH2 Mutant AML - A myeloMATCH Substudy
Eradicating MRD in Patients with AML prior to Stem Cell Transplant (ERASE)
LUNA-2: LND101 in Unresectable Non-Small Cell Lung Cancer: A Randomized Phase II Trial
VIGOR: Vorasidenib as Maintenance Treatment after First-line Chemoradiotherapy in IDH-mutant Grade 2 or 3 Astrocytoma
RAINBO-ORANGE: Treatment of Endometrial Cancer Based On Molecular Features
CCTG is pleased to announce that the 2026 Annual Spring Meeting of Participants will be held April 24-26, 2026, at the Chelsea Hotel in Toronto.
The Canadian Cancer Trials Group (CCTG) is currently seeking applications for a Patient Representative for the Gastro-Intestinal Disease Site Committee. CCTG is an inclusive organization dedicated to building a diverse network. This is a volunteer role for membership on the Gastro-Intestinal Disease Site Committee, the Gastro-Intestinal Disease Site Executive Committee, and the CCTG Patient Representative Committee.
The CCTG Annual Spring Meeting of Participants is fast approaching! We are excited to share important updates and additional information.
This pivotal study is a move away from current ‘one size fits all’ treatment approaches through the testing of a vulvar cancer patients’ tissue to determine the best treatment options. Researchers want to evaluate if the molecular features in tissues removed in the first surgery can direct the need for additional surgery versus a close follow-up for patients with vulvar squamous cell cancer.
CCTG is heartbroken to share the news that, following a long and courageous battle, Suzanne Wood the GI patient representative has passed away. She died at hospital in Toronto with family by her side at the age of 48 on February 9, 2025.
The Canadian Cancer Trials Group (CCTG) has been awarded $742,052 for the PAC5 clinical trial in the CIHR Fall 2024 Project Grant competition. This phase III trial will test lanreotide for the prevention of one of the most severe complications of pancreatic surgery, postoperative pancreatic fistula (POPF).
“The PAC5 clinical trial has the potential to change the standard of care for postoperative pancreatic fistula prophylaxis, significantly benefiting patients and reducing healthcare system costs,” says CCTG Senior Investigator, Chris O’Callaghan.
