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CCTG Connection



Published:
Category: News
Three trials funded GU ASCENDE, IND241 SURELY, EN11 RAINBO-GREEN
Three CCTG trials were recently awarded nearly $7.5M from the Canadian Institutes of Health Research (CIHR) 2022 Spring Project Grant competition. Read More

Published:
Category: Publications
General Review Publications for iRECIST and atypical patterns of response to immuno-oncology drugs, Complementary Medicine Use Amongst Patients with Metastatic Cancer Enrolled in Phase III Clinical Trials, Validating Restricted Mean Survival Time Estimates from Reconstructed Kaplan-Meier Data Against Original Trial Individual Patient Data, and Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response Read More

Published:
Category: Trials
Trial Activation: MEC6
MEC6 A Randomized Phase II Trial of Adjuvant Nivolumab with or without Cabozantinib in Patients with Resected Muscosal Melanoma has been centrally activated.
 
This phase II trial tests whether nivolumab in combination with cabozantinib works in patients with mucosal melanoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
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Published:
Category: Trials

CCTG MAC19 A Randomized Phase III Trial Evaluating the Role of Axillary Lymph Node Dissection in Breast Cancer Patients (cT1 -3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy has closed to further accrual, as the accrual target has been met.

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Published:
Category: News
Matching ExCELLirate Canada funding from The Ontario Research Fund

It was recently announced that ExCELLirate Canada has successfully been granted a Research Infrastructure award of $4,159,049 by the Ontario Research Fund for the Innovation Fund Project Grant "ExCELLirate Canada: Expanding CELL-based Immunotherapy Research Acceleration for Translation and Evaluation".

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Published:
Category: News
Solving Cancer Together Strategic Plan 2022-2027

Following a comprehensive, year-long consultation with the CCTG network, leadership, partners, patient representatives, and staff the new strategic direction for CCTG is unveiled.

“Together, we set down and shared our scientific priorities and supporting activities, captured feedback from our members, patients, and stakeholders and used it to ensure we address the opportunities ahead to conduct trials that will meaningfully improve outcomes for patients with cancer,” said CCTG Director, Dr. Janet Dancey.

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Published:
Category: News
Expansion of the Tissue Bank facilities
The recently launched Centre for Health Innovation, aims to connect researchers from across multiple disciplines to tackle the most pressing human health challenges. A critical part of the centre will be a new home for the CCTG Tumour Tissue Data Repository and includes a large-scale expansion of its histopathology and biobanking resources. Read More

Published:
Category: Office of the Director
Everyone has been touched by cancer either through their own journey or supporting a loved one. Despite better treatments and outcomes, the physical, emotional, and economic burden on patients, their families, and caregivers is likely to increase due to an aging population. In addition, the environment in which trials are conducted is becoming more complex. New therapies, biomarkers, and patient reported outcomes are changing the design, the type of data and the requirements for trial conduct and oversight. Read More