Wednesday, September 10, 2025 Quality of Life publication: Financial difficulty among patients with cancer participating in clinical trialsThe incidence and worsening of financial difficulty (FD) among patients with cancer participating in clinical trials, and their relationship with mortality, quality of life (QOL), and toxicity outcomes have been understudied. The objective of this study was to understand the incidence of FD among Canadian patients participating in systemic therapy trials at baseline and after trial participation, and to assess the relationship of FD with clinical outcomes. Gyawali B, Chen N, Tu D, Pater J. Financial difficulty among patients with cancer participating in clinical trials and its association with patient survival and quality of life (ONLINE). JNCI: Journal of the National Cancer Institute 2025.https://doi.org/10.1093/jnci/djaf221 CRAFT evaluation publicationIn 2021-23, the Canadian Remote Access Framework for Clinical Trials (CRAFT) was implemented as a proof of concept (PoC) pilot to reduce these inequities by bringing trial opportunities to patients living outside metropolitan areas. CRAFT involves a “primary” site that delegates specific trial responsibilities to regional “satellite” centres to form a “trial cluster.” The study's objective was to evaluate the CRAFT pilot implemented in three Canadian provinces: British Columbia, Ontario, and Newfoundland. Bentley C, McTaggart-Cowan H, Kato D, Sundquist S, Dancey JE, Peacock S. Evaluation of the Canadian Remote Access Framework for Clinical Trials (CRAFT) Pilot: a Qualitative Study. Health Policy and Technology 14: 101031. 2025.https://www.sciencedirect.com/science/article/pii/S2211883725000590
