Wednesday, September 23, 2026 Vulvar Squamous Cell Carcinoma: Scientific Progress and Impacts to Pathology Practice Despite vulvar cancer’s rarity, meaningful advances have been made to improve the clinical care of affected patients—particularly with respect to vulvar squamous cell carcinoma (VSCC). These advances are reflected in changes to tumor classification, surgical strategies, early detection of precursors, and targeted therapeutic exploration. Refinements in histopathologic and molecular classification have enhanced diagnostic precision, enabling more accurate prognostication and facilitating personalized therapeutic decision-making, particularly tailored surgical strategies that can be explored through clinical trials—to improve patient outcomes while reducing patient morbidity. Hoang L, Alsolami S, Gilks B, McAlpine JN, Jamieson A. Vulvar Squamous Cell Carcinoma: Scientific Progress and Impacts to Pathology Practice. International Journal of Gynecological Pathology 45: 383-394. 2026.https://www.ovid.com/jnls/intjgynpathology/fulltext/10.1097/pgp.0000000000001188~vulvar-squamous-cell-carcinoma-scientific-progress-and
