Wednesday, September 10, 2025 CX5 surgical approach analysisSHAPE demonstrated that simple hysterectomy was not inferior to radical hysterectomy in patients with low-risk cervical cancer. To further understand the role of preoperative LEEP/conization, clear LEEP/conization margins and surgical approach, analyses were performed regarding patterns of recurrence and death. Mahner S, Trillsch F, Kwon JS, Ferguson SE, Bessette P, Sebastianelli A, Golfier F, Gauthier T, De Kroon C, van Driel W, Tidy J, Williamson K, Goffin F, Polterauer S, Eyjólfsdóttir B, Lee JY, Maguire P, Schmalfeldt B, Shepherd LE, Tu D, Plante M. Surgical approach, preoperative LEEP/conization and patterns of recurrence and death in low-risk cervical cancer – exploratory analysis from the CCTG CX.5/SHAPE trial (ONLINE). International Journal of Surgery 2025.https://journals.lww.com/international-journal-of-surgery/fulltext/9900/surgical_approach,_preoperative_leep_conization.2841.aspx CO26 cost utility analysisTo determine the cost-effectiveness of combined durvalumab and tremelimumab in patients with metastatic colorectal cancer in the intention-to-treat (ITT) and biomarker-enriched populations using direct CCTG CO.26 phase-2 trial data. Ahluwalia M, Parmar A, Loree JM, O’Callaghan CJ, Tu D, Chan KKW, Jonker DJ, Mittmann N, Cheung MC, Feilotter H, Monzon JG, Ng DM, Elfiki TA, Lemay F, Hubay S, Lenehan JG. Cost-Utility Analysis of Durvalumab and Tremelimumab Versus Best Supportive Care in Refractory Metastatic Colorectal Cancer. Value in Health 28: 1001-1008. 2025.https://doi.org/10.1016/j.jval.2025.04.2159
