Wednesday, November 05, 2025 MAC20 secondary analysis publication. Obesity is associated with a higher risk of recurrence, mortality, comorbidities, treatment-related adverse effects, and poor quality of life in patients with breast cancer. Scalable interventions are needed to promote weight loss in this population. Can a remotely delivered weight loss intervention (WLI) reduce weight in a diverse population of women with breast cancer and a body mass index of 27 or higher? Ligibel JA, Ballman KV, McCall L, Goodwin PJ, Alfano CM, Bernstein V, Crane TE, Delahanty LM, Frank E, Hahn O, Hershman DL, Hopkins JO, Irwin M, Mayer EL, Minasian L, Nebeling L, Neuhouser ML, Paskett ED, Spears PA, Stearns V, Thomson CA, Weiss A, White J, Wadden TA, Winer EP, Hudis C, Partridge AH, Carey LA. Impact of a Weight Loss Intervention on 1-Year Weight Change in Women With Stage II/III Breast Cancer: Secondary Analysis of the Breast Cancer Weight Loss (BWEL) Trial. JAMA Oncology 11: 1194-1203. 2025. https://doi.org/10.1001/jamaoncol.2025.2738
