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Proc.Am.Soc.Clin.Oncol. 20, 132a, 2001.Albain K, Green S, Ravdin P, Cobau C, Levine E, Ingle J, Pritchard K, Schneider D, Abeloff M, Norton L, Norton L, Lew D, Martino S, Osborne C. Overall survival after cyclophosphamide, adriamycin, 5-FU, and tamoxifen is superior to T alone in postmenopausal, receptor(+), node(+) breast cancer: new findings from phase III Southwest Oncology Group Intergroup Trial S8814 (INT-0100). Proc.Am.Soc.Clin.Oncol. 20(part 1), 24a, 2001.Barrett E, Verweij J, Gelmon K, Hirte H, Eisenhauer E, Rothenberg M, Demetri G, Seiden M, Hammond A, Rowinsky E, Hao D, Roberts L, Ptaszynski M. Phase I evaluation of NX211, a liposomal lurtotecan (topoisomerase I inhibitor), administered by four schedules: activity in patients with advanced epithelial ovarian cancer. International Conference on Ovarian Cancer, 2001.Batist G, Siu L, MacLean M, Cammisana J, McIntosh L, Schwartz B, Seymour L. NCIC CTG IND.134: A phase I study of a novel glycoconjugated camptothecin (BAY 38-3441) given as a short infusion daily for five days every 3 weeks. Proc Am Assoc Cancer Res 42, 538, 2001.Bezjak A, Shepherd FA, Seymour L, Sadura A, Tu D, Pater J, Giaccone G, Debruyne C, Ahmedzai S. Usefulness of quality of life information in a trial of a matrix metalloproteinase inhibitor marimastat. Quality of Life Research 10(3), 270, 2001.Bezjak A, Heath C, Adam J, Payne D, Tsuji D, Dixon P, Palmer M, Pater J. How to interpret survival data from palliative studies in non-small cell lung cancer. Proc.Am.Soc.Clin.Oncol. 20, 260b, 2001.Bezjak A, Dixon P, Brundage M, Tu D, Pater J, Palmer M, Leong C, Mulroy L, Wright J, Grafton C, Blood P, Lochrin C. Randomized study of single versus fractionated radiotherapy in the palliation of non-small cell lung cancer: NCIC CTG SC.15. International Journal of Radiation Oncology, Biology, Physics 51[3], 20, 2001.Bezjak A, Brundage M, Dixon PF, Palmer M, Pater J, Tu D, Grafton C,Blood P, Leong C, Mulroy LA, Wright J. Is more better? Quality of life results of a Canadian palliative radiotherapy trial in patients with unresectable lung cancer (NCIC CTG SC.15). Quality of Life Research 10(3), 211, 2001.Brundage M, Leis A, Bezjak A, Feldman-Stewart D, Degner L, Velji K, Zetes-Zanatta L, Tu D, Ritvo P, Pater J. Cancer patients' preferences for communicating quality of life information: a qualitative study. International Society for Quality of Life Research, 2001.Brundage M, Bezjak A, Degner L, Feldman-Stewart D, Leis A, Pater J, Ritvo P, Tu D, Velji K. Cancer patients' preferences for communicating quality of life information: results of focus group discussions. Presented: Canadian Association Radiation Oncology, 2001.Connors J, Klimo P, Adams G, Burns B, Cooper I, Meyer R, O'Reilly S, Pater J, Quirt I, Sadura A, Shustik C, Skillings J, Sutcliffe S, Verma S, Yoshida S, Zee B. Comparison of hybrid MOPP/ABV vs alternating MOPP/ABVD chemotherapy for advanced Hodgkin's lymphoma: long-term outcomes, late toxicity and implications of complete vs incomplete response. International Syposium on Hodgkin's Lymphoma, 2001.Connors J, Kouroukis T, Belch A, Crump M, Imrie K, Klasa R, Lohmann R, Powers J, Eisenhauer E. Flavopiridol for mantle cell lymphoma: moderate activity and frequent disease stabilization. Blood (ASH Annual Meeting Abstracts), 2001.Crump M, Tu D, Shepherd L, Levine E, Bramwell V, Pritchard K. Risk of acute leukemia following adjuvant epirubicin-based adjuvant chemotherapy for breast cancer. San Antonio Breast Cancer Symposium, 2001.Crump M, Gluck S, Stewart D, Levine M, Pritchard K, Kirkbride P, Dancey J, O'Reilly S, Shore T, Couban S, Girouard C, Abu-Zahra H, Tu D, Marlin S, Shepherd L. A randomized trial of high-dose chemotherapy with autologous peripheral blood stem cell support compared to standard therapy in women with metastatic breast cancer: a NCIC Clinical Trials Group study. Proc.Am.Soc.Clin.Oncol. 20, 21a, 2001.Dent S, Arnold A, Stewart D, Gertler S, Ayoub J, Batist G, Goss G, Neville A, Soulieres D, Jolivet J, McIntosh L, Seymour L. NCIC CTG IND 120: phase II study of Troxacitabine (BCH-4556) in patients with advanced non-small cell lung cancer. Proc.Am.Soc.Clin.Oncol. 20, 259b, 2001.Dixon P, Bezjak A, Brundage M, Tu D, Palmer M, Pater J, Lochrin C, Leong C, Mulroy L, Wright J, Blood P, Grafton C. NCIC CTG phase III trial of single versus 5 fraction radiotherapy in the palliation of non-small cell lung cancer. Canadian Association Radiation Oncology, 2001.Donehower RC, Stewart D, Eisenhauer E, Wainman N, Moore M, Bonfils C, Reid G. A phase I and pharmacokinetic study of MG98, a human DNA methyltransferase mRNA inhibitor, given as a 2-hour twice weekly infusion 3 out of every 4 weeks. Clinical Cancer Research 7(Suppl), 3680s, 2001.Douillard J, Petersen V, Shepherd F, Paz-Ares L, Arnold A, Tonato M, Ottaway J, Davis M, Van Vreckem A, Humphrey J, Seymour L. Randomised phase II study of BMS-275291 versus placebo in patients with stage IIIb or IV non small cell lung cancer receiving paclitaxel + carboplatin: NCIC Clinical Trials Group BR.18. Eur.J.Can. 37(suppl 6), S19, 2001.Eisenhauer E, Verweij J, Rothenberg M, Demetri G, de Vries E, Gelmon K, Hirte H, Loos W, Seiden M, Sparreboom A, Cameron T, Hamilton M, Ptaszynski M, Onetto N. Phase I evaluation of liposomal topoisomerase I inhibitor, NX211, administered by three schedules to patients with advanced solid tumors. Proc.Am.Soc.Clin.Oncol. 20, 103a, 2001.Gelmon K, Belanger K, Britten C, Soulieres D, Janke S, Dionne J, Powers J, Seymour L, McNally J. A phase I study of T900607 given once every three weeks to patients with advanced refractory cancer. A NCIC Clinical Trials Group Study (NCIC CTG-IND.130). Eur.J.Can. 37(suppl 6), S30, 2001.Gelmon K, Rothenberg M, Verweij J, Hirte H, Demetri G, Sparreboom A, Eisenhauer E, de Vries E, Warren S, Hamilton M, Ptaszynski M, Onetto N. NX 211, a liposomal camptothecin: phase I and pharmacokinetic results. Cancer Investigation 19(Suppl 1), 61-63, 2001.Gelmon K, Stewart D, Ayers D, Fry D, Douglas L, McIntosh L, Seymour L. A phase I study of ZD0473 and docetaxel given once every three weeks in patients with advanced refractory cancer. A NCIC Clinical Trials Group study (NCIC CTG-IND.131). Eur.J.Can. 37(Suppl 6), S72, 2001.Gluck S, Crump M, Stewart D, Levine M, Pritchard K, Kirkbride P, Dancey J, O'Reilly S, Shore T, Couban S, Girouard C, Abuzara H, Tu D, Marlin S, Shepherd L. A randomized trial of high-dose chemotherapy with autologous peripheral blood stem cell support compared to standard chemo therapy in women with metastatic breast cancer: a NCIC Clinical Trials Group study. Eur.J.Can. 37(6), S285, 2001.Goss G, Hirte H, Batist G, Miller W, Stewart D, Matthews S, Seymour L. NCIC CTG IND.122: a phase I/II pharmacokinetics and pharmacodynamic study of ZD1839 (Iressa'TM'). Final phase I results and preliminary phase II results of ZD1839 (750 mg/day) in patients with colorectal cancer. Eur.J.Can. 37(suppl 6), S289, 2001.Goss G, Hirte H, Lorimer I, Miller W, Stewart DJ, Batist G, Matthews S, Douglas L, Seymour L. Final results of the dose escalation phase of a phase I pharmacokinetics, pharmacodynamic and biological activity study of ZD1839: NCIC CTG IND 122. Proc.Am.Soc.Clin.Oncol. 20, 85a, 2001.Hirte HW, Vergote IB, Jeffrey JR, Grimshaw RN, Stuart GC, Mendiola C, Vorobiof DA, Carey MS, Coppieters S, Schwartz B, Tu D, Sadura A, Seymour L. An international multicentre phase III study of BAY 12-9566 versus placebo in patients with advanced ovarian cancer responsive to primary surgery/paclitaxel + platinum containing chemotherapy. South African Society of Medical Oncology & South African Society of Radiation Oncology Congress, 2001.Hirte H, Vergote I, Jeffrey J, Grimshaw R, Stuart G, Mendiola C, Vorobiof D, Carey M, Coppieters S, Schwartz B, Tu,D, Sadura A, Seymour L. An international multicentre phase III study of BAY 12-9566 versus placebo in patients with advanced ovarian cancer responsive to primary surgery/paclitaxel + platinum containing chemotherapy. Proc.Am.Soc.Clin.Oncol. 20, 211a, 2001.Hirte H, Miller W, Major P, Goss G, Stewart D, Batist G, Douglas L, Matthews S, Lorimer I, Seymour L. Initial results of part 2 of a phase I/II pharmacokinetics pharmacodynamic, and biological activity study of ZD1839 (Iressa 'TM'): NCIC CTG IND.122. Clinical Cancer Research 7(suppl), 3761s, 2001.Lorimer I, Parolin D, Robinson S, Goss G, Hirte H, Miller W, Stewart D, Batist G, Douglas L, Matthews S, Seymour L. NCIC CTG IND.122: Immunohistochemical analysis of tumor biopsy specimens from patients undergoing treatment with ZD1839. Clinical Cancer Research 7(suppl), 3708s, 2001.Madarnas Y, Fine S, Sawka C, Shepherd L, Tannock I, Tu D, Levine M.Body size, received dose-intensity and myelotoxicity of adjuvant chemotherapy in relation to outcome of premenopausal women with N1 breast cancer: results from a NCIC Clinical Trials Group randomized controlled trial. North American Association for the Study of Obesity 9, 151S, 2001.Madarnas Y, Fine S, Sawka C, Shepherd L, Tannock I, Tu D, Levine M. Body size, received dose-intensity and myelotoxicity of adjuvant chemotherapy in relation to outcome of premenopausal women with N1 breast cancer: results from a NCIC Clinical Trials Group randomized controlled trial. Breast Cancer Research and Treatment 69, 319, 2001.Maroun J, Jonker D, Seymour L, Goel R, Kocha W, Fisher B. Phase I study of triple drug combination of CPT-11, oxaliplatin and tomudex in previously untreated metastatic colorectal cancer: NCIC Clinical Trials Group, IND.135. Eur.J.Can. 37(suppl 6), S295, 2001.Maroun J, Goel R, Stewart DJ, Tomiak E, Belanger K, Soulieres D, Charpentier D, Seymour L, Matthews S, Jimeno J, Guzman C. Phase I study of aplidine in a 5 day bolus q 3 weeks in patients with solid tumors and lymphomas. Proc.Am.Soc.Clin.Oncol. 20, 83b, 2001.Moore M, Chi K, Ernst S, Belanger K, Tannock I, Bjarnason G, Stewart D, Goel R, Ruether JD, Jolivet J, McIntosh L, Seymour L. A phase II study of troxacitabine in patients with advanced and/or metastatic renal cell carcinoma. NCIC CTG IND.119. Proc.Am.Soc.Clin.Oncol. 20, 193a, 2001.O'Connell M, Skillings J, Windschitl H, Shepherd L, Sargent D, Krook J, Tria Tirona M, Morton R, Rowland K, Rubin J, Kugler J. Phase III trial of high dose levamisole + 5-fluorouracil + leucovorin as adjuvant treatment for high risk colon cancer: an NCCTG/NCIC study. Proc.Am.Soc.Clin.Oncol. 20, 132a, 2001.Parulekar W, Trudeau M, Shepherd L, Ottaway J, Day A, Franssen E, Bramwell V, Levine M, Pritchard K. Incidence and prognostic impact of amenorrhea during adjuvant therapy in high risk premenopausal breast cancer patients: analysis of a NCIC Clinical Trials Group phase III study. Proc.Am.Soc.Clin.Oncol. 20, 25a, 2001.Peters WP, Rosner G, Vredenburgh J, Shpall E, Crump M, Marks L, Cirrincione C, Hurd D, Norton L. Updated results of a prospective, randomized comparison of two doses of combination alkyating agents as consolidation after CAF in high-risk primary breast cancer involving ten or more axillary lymph nodes: CALGB 9082/SWOG 9114/NCIC MA-13. Proc.Am.Soc.Clin.Oncol. 20, 21a, 2001.Raymond E, Paz-Ares L, Izquierdo M, Belanger K, Maroun J, Bowman A, Anthoney A, Jodrell D, Armand J-P, Cortes-Funes H, Germa-Lluch J, Twelves C, Celli N, Guzman C, Jimeno J. Phase I trials with aplidine, a new marine derived anticancer compound. Eur.J.Can. 37(Suppl 6), S32, 2001.Reyno L, Seymour L, Tu D, Pearce L, Dent S, Gelmon K, Walley B, Pritchard K, Pluzanska A, Gorbunova V, Garin A, Jassem J, Pienkowski T, Lebwohl D. Phase III study of DPPE (BMS217380-01) combined with doxorubicin versus doxorubicin alone in metastatic/recurrent breast cancer: a NCIC Clinical Trials Group study. Proc.Am.Soc.Clin.Oncol. 20, 30a, 2001.Seymour L, Siu L, Batist G, Cammisana J, MacLean M, McIntosh L, Petrenciuc O. A phase I study of BAY 38-3441 given as a short infusion daily for five days every 3 weeks. A NCIC Clinical Trials Group Study. Eur.J.Can. 37(suppl 6), S73, 2001.Shepherd F, Giaccone G, Debruyne C, Hirsh V, Smylie M, Rubin S, Martins H, Lamont A, Krzakowski M, Zee B, Sadura A, Seymour L. Randomized double-blind placebo-controlled trial of marimastat in patients with small cell lung cancer following response to first-line chemotherapy: an NCIC CTG and EORTC study. Proc.Am.Soc.Clin.Oncol. 20, 4a, 2001.Shepherd L. The role of neu/erb B-2 as a predictive factor for differential response to adjuvant chemotherapy and tamoxifen: The NCIC Clinical Trials Group experience in retrospective paraffin embedded tissue collection. Reasons for Hope Scientific Conference, 2001.Shepherd L, Parulekar W, Day A, Ottaway J, Bramwell V, Levine M, Pritchard K. Weight gain during adjuvant therapy in high risk pre/perimenopausal breast cancer patients: analysis of a NCIC Clinical Trials Group phase III study. Proc.Am.Soc.Clin.Oncol. 20, 36a, 2001.Shustik C, Belch A, Meyer R, Robinson S, Rubin S, Barr R, Kovacs M, Wilson J, Shepherd L, Djurfeldt M, Zee B. Melphalan-dexamethasone is not superior to melphalan-prednisone as induction therapy in multiple myeloma. Proc.Am.Soc.Clin.Oncol. 20, 298a, 2001.Sidhu K, Fyles A, Eisenhauer E, Shelley W, Stanimir G, Wallwiener D, Ghatage P, Elit L, Bastert G, Powers J, Pouliot J, Oza A. Phase II study of the aromatase inhibitor letrozole in endometrial carcinoma - NCIC CTG IND 126. Proc.Am.Soc.Clin.Oncol. 20, 192b, 2001.Stewart D, Gelmon K, Ayers D, Fry D, Douglas L, McIntosh L, Seymour L. A phase I study of ZD0473 and docetaxel given once every three weeks in patients with advanced refractory cancer. A NCIC Clinical Trials Group study (NCIC CTG-IND.131). Clinical Cancer Research 7(suppl), 3751s, 2001.Tu D, Liu Y. Statistical procedures for the equivalence of two survival rates based on the censored data. Proceedings of the International Statistical Institute 3, 221-222, 2001.Tu D, Zee B, Lam D. Treatment comparisons in stratified clinical trials with survival endpoints. Controlled Clin.Trials 22(2S), 96S, 2001.Vandenberg T, Gelmon K, Panasci L, Crump M, Norris B, Tomiak A, Shenkier T, Lee C, Martin L, Matthews S, Seymour L, Douglas L. A phase II trial of ZD0473 in patients with metastatic breast cancer a NCIC Clinical Trials Group Study (NCIC CTG-IND 129). Proc.Am.Soc.Clin.Oncol. 20, 58b, 2001.Vandenberg T, Gelmon K, Panasci L, Crump M, Norris B, Tomiak A, Shenkier T, Douglas L, Matthews S, Seymour L. A phase II trial of ZD0473 in patients with metastatic breast cancer. A NCIC Clinical Trials Group study (NCIC CTG-IND.129). Eur.J.Can. 37(suppl 6), S194, 2001.Winquist E, Moore M, Chi K, Ernst S, Hirte H, Iscoe N, Venner P, Huan S, Powers J, Seymour L, Boucher T. NCIC CTG IND.128. A phase II study of a farnesyl transferase inhibitor (SCH 66336) in patients with unresectable or metastatic transitional cell carcinoma of the urothelial tract failing prior chemotherapy. Proc.Am.Soc.Clin.Oncol. 20, 197a, 2001.Yee K, Pater J, Pho L, Zee B. Enrollment of elderly patients in cancer treatment trials in Canada. Proc.Am.Soc.Clin.Oncol. 20, 392a, 2001. 2000Bakal J, Tu D. Nonparametric regression analyses to identify prognostic factors for women with early breast cancer. Statistical Society of Canada, 2000.Dixon P, Brundage M, Palmer M, Zee B, Pater J, Leong C, Mulroy L, Wright J, Grafton C, Blood P, Lochrin C. Characteristics of lung cancer patients entered on a Canadian palliative radiotherapy study (NCIC Clinical Trials Group SC.15 study). Lung Cancer 29 (Suppl 1), 171, 2000.Brundage M, Zee B, Palmer M, Bezjak A, Dixon P, Pater J. The use of a patient symptom diary to assess palliation in lung cancer patients: agreement with physician assessment and EORTC QLQ scores. Quality of Life Research 9(3), 274, 2000.Butler L, Bezjak A, Carey M, Bacon M, Zee B, Stewart D, Brundage M. Determining the relationship between toxicity and quality of life using OV10, an international ovarian cancer chemotherapy trial. Quality of Life Research 9(3), 287, 2000.Davis A, Moore M, Gelmon K, Siu L, Brittain M, Beaulieu N, Bonfils C, Firby P, Klamut H, Eisenhauer E. Phase 1 and pharmacodynamic study of human DNA methyltransferase (MeTase) antisense oligodeoxynucleotide (ODN), MG98, administrered as 21-day infusion q4 weekly. Clinical Cancer Research 6(Suppl), 4517, 2000.Eisenhauer E, Gelmon K, Hirte H, Fisher B, Walsh W, Ptaszynski M, Onetto N, Zee B. Predictors of inter-patient toxicity in a phase I trial of NX211 given in a daily x 3 intravenous infusion schedule every 3 weeks. Clinical Cancer Research 6(Suppl), 4514, 2000.El-Sayed S, Nabid A, MacKenzie R, Gelinas M, Hay J, Shelley W, Berthelet E, Lau H, Duncan G, Epstein J, James K, Tu D, Burns P, Ottaway J. Prophylaxis of radiation associated mucositis in patients with head and neck cancer: results of a double blind phase III trial evaluating the clinical efficacy of an antimicrobial lozenge and utilizing the newly validated mucositis scoring system. Int.J.Rad.Oncol.Biol.Phys. 48, 321, 2000.Gelmon K, Eisenhauer E, Reyno L, Hirte H, Britten C, Lee U, Fisher B, Ayers D, D'Aloisio S, Stafford S, Hamilton M, Ptaszynski M, Onetto N. Phase I study of NX211 (liposomal lurtotecan) given as an intravenous infusion on days 1, 2, & 3 every 3 weeks in patients with solid tumours -- an NCIC Clinical Trials Group study. Proc Am Assoc Cancer Res, 2000.Goel R, Chouinard E, Stewart D, Huan S, Hirte H, Stafford S, Walsh W, Waterfield B, Roach J, Schwartz B, Matthews S, Seymour L. Phase I/pharmacokinetic study of the metalloproteinase and angiogenesis inhibitor Bayer 12-9566 in conjunction with 5-fluorouracil/folinic acid. Proc.Am.Soc.Clin.Oncol. 19, 232a, 2000.Goss G, Lorimer I, Miller W, Hirte H, Stewart D, Batist G, Matthews S, Averbuch S, Seymour L. A phase I, dose escalation, pharmacokinetics and pharmacodynamic study of ZD1839: NCIC CTG IND.122. Clinical Cancer Research 6(Suppl), 4543, 2000.Goss G, Hirte H, Batist G, Stewart D, Miller W, Lorimer I, Abugaber A, Matthews S, Seymour L. NCIC CTG IND.122: A two-part phase I pharmacokinetic and pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839. Proc.Am.Soc.Clin.Oncol. 19, 225a, 2000.Hamilton M, Sparreboom A, Loos W, Verweij J, Demetri G, Gelmon K, Eisenhauer E, Warren S, Ptaszynski M. Pharmacokinetics of NX 211 (liposomal lurtotecan) in phase I patients with solid tumours. Clinical Cancer Research 6(Suppl), 4513, 2000.Hirte H, Vergote I, Jeffrey J, Grimshaw R, Stuart G, Mendiola C, Vorobiof D, Carey M, Coppieters S, Tu D, Sadura A, Seymour L. An international multicentre phase III study of BAY 12-9566 versus placebo in patients with advanced ovarian cancer responsive to primary surgery/ paclitaxel + platinum containing chemotherapy. Ann.Oncol. 11, 714, 2000.Kraut M, Rusch V, Crowley J, Gandara D. Induction chemoradiation plus surgical resection is feasible and highly effective treatment for pancoast tumors: initial results of SWOG 9416 (intergroup 0160) trial. Proc.Am.Soc.Clin.Oncol. 19, 487a, 2000.Marlin S, Fourt M, Koski T, Sinnott C, Degendorfer P, Green D. The assessment of educational needs and design of educational programs for ethics and regulatory aspects of NCIC Clinical Trials Group (NCIC CTG) Trials. Controlled Clin.Trials 21(2S), 131s, 2000.Maroun J, Belanger K, Seymour L, Soulieres D, Charpentier D, Goel R, Stewart D, Tomiak E, Jimeno J, Matthews S. Phase I study of aplidine in a 1 hour daily infusion x 5 q 3 weeks in patients with solid tumors and low and intermediate grade Non Hodgkin's Lymphomas. A NCIC Clinical Trials Group study. Ann.Oncol. 11(Suppl 4), 2000.Maroun J, Belanger K, Seymour L, Soulieres D, Charpentier D, Goel R, Stewart D, Tomiak E, Jimeno J, Matthews S. Phase I study of aplidine in a 5 day bolus q 3 weeks in patients with solid tumors and lymphomas. Clinical Cancer Research 6(Suppl), 4509, 2000.Moore M, Siu L, Oza A, MacLean M, Fisher B, Jordan C, Slapak C, Seymour L. A phase I study of vinorelbine plus multidrug resistance inhibitor LY 335979 in patients with advanced solid tumors. Clinical Cancer Research 6(Suppl), 4504, 2000.Moore M, Hamm J, Eisenberg P, Dagenais M, Hagan K, Fields A, Greenberg B, Schwartz B, Ottaway J, Zee B, Seymour L. A comparison between gemcitabine and the matrix metalloproteinase inhibitor BAY12-9566 in patients with advanced pancreatic cancer. Proc.Am.Soc.Clin.Oncol. 19, 240a, 2000.Ottaway J, Fischer P, Seymour L, Correa R, Day A. Data collection using remote data entry in the cooperative group setting: NCIC CTG experience. Controlled Clin.Trials 21(2S), 114s, 2000.Oza A, Eisenhauer E, Swenerton K, Elit L, Ghatage P, Carey M, Faught W, McIntosh L, Dorr A, Holmlund J. Phase II study of c-raf kinase antisense oligonucleotide ISIS 5132 in patients with recurrent ovarian cancer (NCIC IND.116). Clinical Cancer Research 6(Suppl), 4572, 2000.Palmer M, Broekhoven M, Garrah A, Tu D. CTASSIST: A computer program for patient randomization and tracking of drug distribution. Controlled Clin.Trials 21(2S), 110s, 2000.Palmer M, Zee B, Bezjak A, Pater J. The timing of baseline quality of life in clinical trials. Quality of Life Research 9(3), 337, 2000.Paul N, Roche K. Screening patients for clinical trials: factors affecting the ratio of time spent to accrual. Controlled Clin.Trials 21(2S), 95s, 2000.Pearcey R, Brundage M, Drouin P, Jeffrey J, Johnston D, Lukka H, MacLean G, Souhami RL, Stuart G, Tu D. A clinical trial comparing concurrent cisplatin and radiation therapy versus radiation alone for locally advanced squamous cell carcinoma of the cervix carried out by the NCIC Clinical Trials Group. Proc.Am.Soc.Clin.Oncol. 19, 378a, 2000.Roche K, Paul N, Whitehead M, Walker H, Pater J, Zee B. Predicting trial complexity and time consumption: further results of the workload measurement study of the NCIC Clinical Trials Group. Proc.Am.Soc.Clin.Oncol. 19, 449a, 2000.Rothenberg M, Gelmon K, Eisenhauer E, Hirte H, Vermeulen W, Naujoks R, Hamilton M, Warren S, Onetto N, Demetri G. Phase I evaluation of liposomal topoisomerase I inhibitor, NX 211, given on days 1, 2, 3 or days 1, 8 every 3 weeks to patients with advanced solid tumors. Proc.Am.Soc.Clin.Oncol. 19, 198a, 2000.Sargent D, Goldberg RM, Macdonald J, Labianca R, Haller D, Shepherd L, Seitz J, Francini G. Adjuvant chemotherapy for colon cancer is beneficial without significantly increased toxicity in elderly patients: results from a 3351 patient meta-analysis. Proc.Am.Soc.Clin.Oncol. 19, 241a, 2000.Seymour L, Hirte H, Stafford S, Goss G, Miller W, Belfer H, Batist G, Hanna P, Matthews S, Averbuch S. NCIC CTG IND.122: A multicentre phase I dose-escalation study of ZD1839 with pharmacodynamic endpoints -- feasibility of serial tumour sampling. Ann.Oncol. 11(Suppl 4), 2000.Shepherd FA, Arnold A, Neville A, Cormier Y, Davis M, Wierzbicki R, Dancey J, Rusthoven J, Fisher B, Eisenhauer E. Phase II study of MTA (Alimata) and cisplatin in patients with advanced non-small cell lung cancer. Proc.Am.Soc.Clin.Oncol. 19, 507a, 2000.Siu L, Gelmon K, Moore M, Britten C, D'Aloisio S, MacLean M, Wainman N, Ayers D, Firby P, Besterman J, Reid G, Eisenhauer E. 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Congress of Cytokines and Growth Factors in Cancer, 1993.Brundage M, Pater J, Zee B. Assessing the reliability of two treatment toxicity scales: reason for concern. Proc.Am.Soc.Clin.Oncol. 12, 184, 1993.Cairncross G, Macdonald D, Ludwin S, Lee D, Cascino T, Buckner J, Dropcho E, Fulton D, Stewart D, Schold C, Wainman N, Eisenhauer E. Phase II study of chemotherapy for anaplastic oligodendroglioma (preliminary report). Proc.Am.Soc.Clin.Oncol. 12, 175, 1993.Cormier Y, Eisenhauer E, Gregg R, Ayoub J, Goss G, Stewart D, Muldal A, Tarasoff P. Gemcitabine: an active new agent in patients with previously untreated small cell lung cancer. Proc.Am.Soc.Clin.Oncol. 12, 330, 1993.Eisenhauer E, Ten Bokkel-Huinink W, Swenerton K, Mangioni C, van der Burg M, Kerr I, Gianni L, Buser K, Vermorken J, Onetto N, Winograd B, Canetta R. Toxicity of Taxol: a European-Canadian trial of high vs low dose and short vs long infusion in ovarian cancer. Clinical Oncology Society of Australia, 1993.Grever M, Kopecky K, Head D, Foucar K, Cassileth P, Golomb H, Habermann T, Rai K, Eisenhauer E, Appelbaum F, Cheson B. A randomized comparison of deoxycoformycin versus alpha-2a interferon in previously untreated patients with hairy cell leukemia: an updated report on the NCI-sponsored intergroup study (SWOG, ECOG, CALGB, NCIC CTG). Blood (ASH Annual Meeting Abstracts), 1993.Latreille J, Stewart D, Laberge F, Hoskins P, Rusthoven J, McMurtrie E, Warr D, Yelle L, Walde D, Shepherd F, Dhaliwal H, Findlay B, Mee D, Pater J, Zee B, Johnston D. Dexamethasone improves the efficacy of granisetron in the first 24 hours following high dose cisplatin chemotherapy. Proc.Am.Soc.Clin.Oncol. 12, 133, 1993.Latreille J, Stewart D, Laberge F, Hoskins P, Rusthoven J, McMurtrie E, Warr D, Yelle L, Walde D, Shepherd F, Dhaliwal H, Findlay B, Mee D, Pater J, Zee B, Johnston D. Dexamethasone improves the efficacy of granisetron in the first 24 hours following high dose cisplatin chemotherapy. Eur.J.Can. 29A(Suppl.6), S208, 1993.Macdonald D, Cairncross G, Eisenhauer E. NCIC CTG phase II study of topotecan for malignant glioma. International Conference of Brain Tumour Research and Therapy, 1993.Macdonald D, Cairncross G, Ludwin S, Lee D, Cascino T, Buckner J, Dropcho E, Fulton D, Stewart D, Schold C, Wainman N, Eisenhauer E. NCIC CTG phase II study of chemotherapy for anaplastic oligodendroglioma. International Conference of Brain Tumour Research and Therapy, 1993.Muldal A, Pho L, Eisenhauer E. Establishment of an adverse event reporting database: the NCIC Clinical Trials Group experience. Controlled Clin.Trials 14(5), 428, 1993.Myles J. Design issues of a pilot study to determine equivalent toxicity with G-CSF support. Clinical Trials in Oncology, 1993.Osoba D, Zee B, Pater J, Quirt I. Lessons learned from measuring health-related quality of life in an adjuvant trial of gamma interferon versus levamisole in patients with resected malignant melanoma. Proc.Am.Soc.Clin.Oncol. 12, 434, 1993.Osoba D. for the Quality of Life Committee. Measuring health-related quality of life in clinical trials: the NCIC Clinical Trials Group experience. Clinical Trials in Oncology, 1993.Paul N. The success of clinical trials depends on good communication. Joint meeting of EORTC SGDM and BODMA, 1993.Swenerton K, Eisenhauer E, Ten Bokkel-Huinink W, Myles J, Mangioni C, van der Burg M, Kerr I, Gianni L, Vermorken J, Buser K, Sadura A, Bacon M, Santabarbara P, Onetto N, Canetta R. Taxol in relapsed ovarian cancer: high vs low dose and short vs long infusion: a European-Canadian study coordinated by the NCI Canada Clinical Trials Group. Proc.Am.Soc.Clin.Oncol. 12, 256, 1993.Tallman M, Andersen J, Appelbaum F, Schiffer C, Woods W, Feusner J, Ogden A, Weinstein H, Shepherd L, Wiernik P, Rowe J. Phase III randomized study of all-trans retinoic acid versus ctyosine arabinoside and daunorubicin as induction therapy for patients with previously untreated acute promyelocytic leukemia: preliminary toxicity results. APL International Meeting, 1993.Trudeau M, Eisenhauer E, Lofters W, Norris B, Muldal A, Letendre F, Vandenberg T, Verma S. Phase II study of taxotere as first line chemotherapy for metastatic breast cancer. Proc.Am.Soc.Clin.Oncol. 12, 64, 1993.van der Burg M, Myles J, Hoskins P, Ten Bokkel-Huinink W, Eisenhauer E. CA-125 is an unreliable marker for monitoring response to taxol therapy in patients with relapsed ovarian cancer. Eur.J.Can. 29A(Suppl.6), S133, 1993.Zaniboni A, Erlichman C, Seitz J, Shepherd L, Milan C, Labianca R, Torri V, Pignon J, Zee B, Marsoni S. FUFA increases disease-free survival in resected B2,C colon cancer: results of a prospective pooled analysis of three randomised trials. Proc.Am.Soc.Clin.Oncol. 12, 191, 1993.Zee B, Pater J, Torri V, Marsoni S, Pancera G, Milan C, Pignon J. Salvaging clinical trials forced to terminate early by results of external information. Controlled Clin.Trials 14(5), 439, 1993.Zee B, Pater J, Torri V, Marsoni S, Pancera G, Milan C, Pignon J.Salvaging trials forced to terminate early by external results and a design of pooled-international-trials. Clinical Trials in Oncology, 1993.Zee B, Pho L, Koski B. System for monitoring timing of data review and entry. Controlled Clin.Trials 14(5), 431, 1993.Zee B. Growth curve model for quality of life data with missing and informative right censoring. Joint ASA Biometrics Meeting, 1993. 1992Ciampi A, Zee B, Hendricks L, Pater J. Correcting for confounding in survival analysis: the tree- growing approach. Statistical Society of Canada, 1992.Connors J, Klimo P, Adams G, Burns B, Cooper I, Meyer R, O'Reilly S, Pater J, Quirt I, Sadura A, Shustik C, Skillings J, Sutcliffe S, Verma S, Yoshida S, Zee B. MOPP/ABV hybrid versus alternating MOPP/ABVD for advanced Hodgkin's disease. Proc.Am.Soc.Clin.Oncol. 11, 317, 1992.Coppin C, Gospodarowicz M, Dixon P, Tannock I, Zee B, Sullivan L. Improved local control of invasive bladder cancer by concurrent cisplatin and preoperative or radical radiation. Proc.Am.Soc.Clin.Oncol. 11, 198, 1992.Cormier Y, Eisenhauer E, Gregg R, Stewart D, Muldal A. Gemcitabine is active in patients with previously untreated extensive small cell lung cancer. A phase II study. Cancer Investigation 2(1), 55-56, 1992.Desjardins C, Pater J, Zee B, Torri W, Marsoni S, Colombo N, Bonazzi C. Prognostic factors after a negative second-look laparotomy in ovarian cancer: a Canada-Italy study. Ann.Oncol. 3(Suppl.5), 107, 1992.Egorin M, Reyno L, Sridhara R, Canetta R, Swenerton K, Pater J, Burroughs J, Novak M, Gregory W. Application to ovarian cancer of a mathematical model relating response duration to amount of subclinical resistant disease. Presented: AACR, 1992.Eisenhauer E, Ten Bokkel-Huinink W, Swenerton K, Mangioni C, van der Burg M, Kerr I, Gianni L, Buser K, Vermorken J, Onetto N, Winograd B, Canetta R. Toxicity of taxol: a European-Canadian trial of high vs low dose and short vs long infusion in ovarian cancer coordinated by the NCI Canada Clinical Trials Group. NCI Workshop on Taxol and Taxus, 1992.Eisenhauer E, Cormier Y, Gregg R, Stewart D, Muldal A. Gemcitabine is active in patients with previously untreated extensive small cell lung cancer. A phase II study of the NCIC Clinical Trials Group (NCIC CTG). Proc.Am.Soc.Clin.Oncol. 11, 309, 1992.Eisenhauer E, Belanger K, Erlichman C, Gregg R, Shore T, Dallaire B, Gyves J, Grillo-Lopez A. DUP 937: a new anthrapyrazole in clinical trials. NCI-EORTC Symposium on New Drugs in Cancer Therapy, 1992.Grever M, Kopecky K, Head D, Cassileth P, Golomb H, Habermann T, Rai K, Eisenhauer E, Cheson B. A randomized comparison of deoxycoformycin versus alpha-2a interferon in previously untreated patients with hairy cell leukemia. An NCI-sponsored intergroup study (SWOG, ECOG, CALGB, NCIC CTG). Proc.Am.Soc.Clin.Oncol. 11, 264, 1992.Kaizer L, Warr D, Hoskins P, Latreille J, Lofters W, Geggie P, Palmer M, Zee B, Pater J, Levy M. The effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in patients receiving moderately emetogenic chemotherapy. Proc.Am.Soc.Clin.Oncol. 11, 381, 1992.Koski B, Pater J. Quality assurance and multicentre clinical trials. Controlled Clin.Trials 13(5), 430, 1992.Levitt M, Warr D, Yelle L, Rayner H, Latreille J, Potvin M, Warner E, Pritchard K, Palmer M, Zee B, Pater J. The anti-emetic effect of ondansetron is not superior to dexamethasone plus metoclopramide in CMF chemotherapy for breast cancer. Proc.Am.Soc.Clin.Oncol. 11, 388, 1992.Maroun J, Skillings J, MacCormick R, Potvin M, Davidson J, Eisenhauer E. Phase II study of DUP-937 in colorectal carcinoma. A Canadian National Cancer Institute Clinical Trials Group (NCIC CTG) study. Proc.Am.Soc.Clin.Oncol. 11, 179, 1992.Osoba D, Zee B, Sadura A, Pater J. Measurement of quality of life in a clinical trial of interferon versus levamisole in malignant melanoma. Clin.Invest.Med. 15(4)(Suppl), A87, 1992.Palmer M, Pater J. The parodox of rapid accrual. Controlled Clin.Trials 13(5), 428, 1992.Palmer M, Zee B. The measurement of visual analogue scale data is not a burden. Controlled Clin.Trials 13(5), 435, 1992.Pater J, Darko E, Zee B. Impact of nausea and vomiting on quality of life patients receiving cytotoxic chemotherapy. Ann.Oncol. 3(Suppl.5), 177, 1992.Pater J, Niezgoda H, Zee B. Validation of the EORTC-QLC -- a comparison with four other instruments in a heterogenous group of cancer patients. Ann.Oncol. 3(Suppl.5), 175, 1992.Paul N, Wainman N, Eisenhauer E, Pho L, Koski B, Pieters B. Continuing review of trials by local ethics boards: a reminder system for keeping participating centres on track. Controlled Clin.Trials 13(5), 431, 1992.Paul N, Eisenhauer E, Wainman N, Sadura A, Koski B. Form enhances content: development of a generic protocol. Controlled Clin.Trials 13(5), 395, 1992.Pritchard K, Paterson AHG, Fine S, Paul N, Pater J, Zee B, Warr D, Knowling M, Abu-Zahra H, Levine M, Bramwell V, Walde PD, Norris B, Poljicak M, Perrault D, Ragaz J, Verma S, Bowman D. A randomized trial of CMF chemotherapy added to tamoxifen as adjuvant therapy in post-menopausal women with node-positive estrogen and/or progesterone receptor +ve breast cancer. Clin.Invest.Med. 15(4)Suppl, 1992.Pritchard K, Paterson A, Fine S, Paul N, Pater J, Zee B, Warr D, Knowling M, Abu-Zahra H, Levine M, Bramwell V, Norris B, Poljicak M, Perrault D, Ragaz J, Verma S, Bowman D. A randomized trial of CMF chemotherapy added to tamoxifen as adjuvant therapy in post-menopausal women with node-positive estrogen and/or progesterone receptor positive breast cancer. Proc.Am.Soc.Clin.Oncol. 11, 60, 1992.Pritchard K, Paterson AHG, Fine S, Paul N, Pater J, Zee B, Warr D, Knowling M, Abu-Zahra H, Levine M, Bramwell V, Walde D, Norris B, Poljicak M, Perrault D, Ragaz J, Verma S, Bowman D. A randomized trial of CMF chemotherapy added to tamoxifen as adjuvant therapy in post-menopausal women with node-positive estrogen and/or progesterone receptor breast cancer. Royal College Meeting, 1992.Reyno L, Egorin M, Canetta R, Jodrell D, Swenerton K, Pater J, Burroughs J, Novak M, Sridhara R. Relationships between carboplatin (CBDCA) exposure, response and toxicity in combination with cyclophosphamide (CYC) in the treatment of ovarian cancer. Proc.Am.Soc.Clin.Oncol. 11, 114, 1992.Rusthoven J, Eisenhauer E, Mazurka J, Hirte H, O'Connell G, Jeffrey J, Swenerton K, Muldal A. Phase I clinical trial of escalating doses of interleukin-3 (IL-3) in patients with relapsed ovarian cancer receiving carboplatin. Proc.Am.Soc.Clin.Oncol. 11, 237, 1992.Ten Bokkel-Huinink W, Swenerton K, Eisenhauer E, Onetto N, Winograd B. Toxicity of taxol: a European-Canadian trial of high vs low dose and short vs long infusion in ovarian cancer. Ann.Oncol. 3(Suppl.5), 101, 1992.Vandenberg T, Pritchard KI, Eisenhauer E, Trudeau M, Norris B, Lopez P, Verma S, Buckman RA, Muldal A. Phase II study of weekly 10-EDAM (edatrexate) as first line chemotherapy for metastatic breast cancer. A NCIC Clinical Trials Group (NCIC CTG) study. Proc.Am.Soc.Clin.Oncol. 11, 51, 1992.Verma S, Quirt I, Eisenhauer E, Young V. A phase II study of 10-EDAM in metastatic malignant melanoma. Proc.Am.Soc.Clin.Oncol. 11, 347, 1992.Wainman N, Paul N, Brundage M, Pater J, Eisenhauer E, Koski B, Sadura A, Walsh W. Common toxicity criteria: The NCIC Clinical Trials Group (NCIC CTG) experience. Controlled Clin.Trials 13(5), 435, 1992.Zee B. One-sided test for clinical trials with group sequential design that allow early acceptance of negative result. Controlled Clin.Trials 13(5), 380, 1992.Zee B, Ciampi A, Pater J, Lou Z, Hendricks L. Covariate adjustment in randomized trials incorporating regression tree method. Statistical Society of Canada 1992. 1991Brundage M, Pater J. Reporting of toxicity data in prospective clinical trials: current patterns of practice and implications for analysis. Controlled Clin.Trials 12(5), 681, 1991.Carmichael J, Danjoux C, Fraser R, Krepart G, O'Connell G, Pater J, Roy M, Shelley W, Starreveld A, Swenerton K. Clinical trial comparing abdominal-pelvic radiation versus cyclophosphamide + cisplatinum chemotherapy in patients with epithelial ovarian carcinoma having only microscopic residual disease following surgery (NCIC Trial OV.7). Gyn Oncol Canada Meeting, 1991.Hryniuk W. for the NCI-Canada, Clinical Trials Group. Randomized trial of escalated vs standard BACOP (Bleomycin-Adriamycin-Cyclophosphamide-Oncovin-Prednisone) for intermediate grade lymphoma. Proc.Am.Soc.Clin.Oncol, 1991.Johnston D. Lessons learned from coordinating antiemetic trials. Antiemetics -- Current Status and Future Directions, 1991.Johnston D, Palmer M, Pater J. Interrelationships between anxiety and nausea in cancer patients receiving chemotherapy. Eur.J.Can. 27(S2), S298, 1991.Koski B, Pater J. Does central monitoring of the timeliness of forms result in a decrease in the quality of data. Controlled Clin.Trials 12(5), 708, 1991.Lu HX, Pater J, Zee B, Evans WH, Feld R, Coy P, Murray N, Ciampi A. Disease extent influences the impact of other prognostic factors in patients with small cell lung cancer. Eur.J.Can. 27(2), 1991.Maroun J, Belanger K, Jolivet J, Stewart D, Wong B, Grillo-Lopez A, Eisenhauer E. Phase I trial of the anthrapyrazole DUP-937 given weekly x3 every 5 weeks. Proc.Am.Assoc.Cancer Res, 1991.Murray N, Coy P, Pater J, Hodson I, Arnold A, Kostashuk E, Dixon P, Zee B, Sadura A, Ayoub J, Levitt M, Wierzbicki R, Payne D, Maroun J, Wilson K. The importance of timing for thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer. Proc.Am.Soc.Clin.Oncol. 10, 243, 1991.Palmer M, Pater J. Does participation on concurrent clinical trials compromise the quality of the data or its timely submission? Controlled Clin.Trials 12(5), 713, 1991.Palmer M, Koski B, Goodlow J, Zee B. So clean it squeaks -- comparison of data collected by two independent groups on the same trial. Controlled Clin.Trials 12(5), 693, 1991.Pater J, Smaldone L, Zee B, Goodlow J, Rusthoven J, Rozencweig M. Simultaneous randomization to multiple dose levels and an active comparator as a means of determining the minimal effective dose of an investigational agent. Controlled Clin.Trials 12(5), 696, 1991.Pater J. Prognostic factors in emesis. Antiemetics -- Current Status and Future Directions, 1991.Paul N. Implementing the European Community good clinical practice guidelines in Canada: a national cooperative group's report. Controlled Clin.Trials 12(5), 682, 1991.Paul N, Pater J, Whitehead M, Sadura A. Methods of toxicity data collection: an evaluation of the relative effectiveness of the case report flow sheet, the patient symptom diary, and the quality of life questionnaire. Controlled Clin.Trials 12(5), 648, 1991.Sadura A, Pater J, Levine M, Osoba D. Quality of life assessment: patient complicance with questionnaire completion. Controlled Clin.Trials 12(5), 708, 1991.Shepherd F, Rusthoven J, Goss P, Eisenhauer E. A phase I-II trial of high dose cisplatin, etoposide and GM-CSF for small cell lung cancer. Proc.Am.Soc.Clin.Oncol, 1991.Slamet L, Pater J, Zee B, Osoba D, Warr D, Rusthoven J. Inconsistency of prognostic factors and post chemotherapy nausea and vomiting. Eur.J.Can. 27(2), 1991.Stewart D, Eisenhauer E, McDonald D, Cairncross G, Lopez P. NCI Canada phase II study of tiazofurin in the treatment of glioblastoma multiforme. International Conference of Brain Tumour Research and Therapy, 1991.Stewart D, Verma S, Eisenhauer E, Pritchard K, Buckman R, Skillings J, Vandenberg T. NCI Canada phase II study of weekly oral menogaril as first line chemotherapy for recurrent breast cancer. Proc.Am.Soc.Clin.Oncol, 1991.Warr D. Phase I/II 5-HT3 antagonist trials. Antiemetics -- Current Status and Future Directions, 1991.Weinerman B, Shepherd F, Eisenhauer E, Stewart D, Mertens W, MacCormick R, Venner P, Cormier Y, Belanger K, Ayoub J, Tannock I, Spaulding R. NCI Canada phase II studies of sulofenur in untreated small cell lung and renal cell cancers. Proc.Am.Soc.Clin.Oncol. 10, 251, 1991.Zee B. Assessing quality of life in antiemetic studies: preliminary results. Antiemetics -- Current Status and Future Directions, 1991.Zee B, Pater J. Recursive structural model: an approach to analyze data with treatment adherence problem in randomized clinical trials. Controlled Clin.Trials 12(5), 625, 1991. 1990Eisenhauer E, Johnston J, Cassileth P, Kraut E. Durability of 2-Deoxycoformycin induced remissions in patients with hairy cell leukemia. International Cancer Congress, 1990.Eisenhauer E, Wierzbicki R, Venner P, Skillings J, Letendre F. Phase II trial of recombinant tumour necrosis factor (rTNF) in patients with renal cell carcinoma. Proc.Am.Soc.Clin.Oncol. 9, 139, 1990.Erlichman C, Moore M, Kerr I, Wong B, Eisenhauer E. Phase I trial of the anthrapyrazole CI-937. Proc.Am.Soc.Clin.Oncol, 1990.Fine S, Rusthoven J, Erlichman C, Wilson K, Johnston D, Zee B, Pater J, Smaldone L. Dose Response in the control of nausea and vomiting with batanopride. A multicentre double-blind randomized trial of the Clinical Trials Group of the NCIC Clinical Trials Group. Proc.Am.Soc.Clin.Oncol. 9, 1316, 1990.Johnston D. Coordinating a pivotal clinical trial: an educational experience. Controlled Clin.Trials 11(4), 306, 1990.Koski B. Impact of the monitoring of center performance. Controlled Clin.Trials 11(4), 304, 1990.Loomer S. Does center size affect protocol compliance on multicentered clinical trials? The NCIC Clinical Trials Group's Experience. Controlled Clin.Trials 11(4), 297, 1990.Moertel CG, Loprinzi CL, Witzig TE, Wieand H, Gonchoroff NJ, Reiman HM, Galandiuk S, Fitzgibbons R, Barlow JF, Donohue JH. The dilemma of stage B-2 colon cancer. Is adjuvant therapy justified? A Mayo Clinic/North Central Cancer Treatment Group study. Proc.Am.Soc.Clin.Oncol. 9, 108, 1990.Murray N, Coppin C, Rapp E, Pater J, Cormier Y, Evans W, Hodson I, Clark D, Feld R, Arnold A, Ayoub J, Wilson K, Latreille J, Wierzbicki R, Hill D. The Canadian multicenter trial in non-small cell lung cancer: an analysis of drug delivery. Proc.Am.Soc.Clin.Oncol. 9, 225, 1990.Pater J. For the Ovarian Cancer Trials Committee of the NCIC CTG. Cyclophosphamide/cisplatin (CDDP) versus cyclophosphamide/carboplatin (CBDCA) in macroscopic residual ovarian cancer. Initial results of a NCIC Clinical Trials Group Trial. Proc.Am.Soc.Clin.Oncol. 9, 602, 1990.Paul N. Industry involvement in cooperative group trials: effects on data management. Controlled Clin.Trials 11(4), 280, 1990.Rusthoven J. On behalf of the NCIC Clinical Trials Group and Bristol Myers Squibb. Randomized, double blind controlled trial testing the dose response and overall efficacy of batanopride in patients receiving moderately emetogenic chemotherapy. Ann.Oncol. 1(Suppl, abstr W9:18, 1990.Rusthoven J, Levin L, Eisenhauer E, Carmichael J. A phase I study of GM-CSF, cyclophosphamide, and escalating doses of carboplatin (CBDCA) in chemotherapy-naive patients with ovarian cancer. Ann.Oncol. 1 (Suppl, abstr W1:12), 1990.Rusthoven J, O'Connell G, Mazurka J, Eisenhauer E, MacFarlane D, Levin L, Hirte H. A phase I study of GM-CSF, cyclophosphamide, and escalating doses of carboplatin (CBDCA) in chemotherapy-naive patients with ovarian cancer. Ann.R.Coll.Phy.Surg.Can, 1990.Sadura A. Determining ineligibility: the role of central review of supporting documentation. Controlled Clin.Trials 11(4), 288, 1990.Venner P. Granisetron for high dose cisplatin induced emesis: a randomized double blind study. Proc.Am.Soc.Clin.Oncol. 9, 320. 1990.Weinerman B, Shah A, Fields A, Kerr I, et al. A randomized trial of continuous systemic infusion vs bolus therapy with 5 fluorouracil in metastatic measurable colorectal cancer. Proc.Am.Soc.Clin.Oncol. 9, 399, 1990.Zee B, Pater J. Sample size for trials where survival depends on first response rate. Controlled Clin.Trials 11(4), 301, 1990. 1989Bergsagel D, Belch A, Wilson K, O'Reilly D, Zee B. A controlled trial of daily etidronate disodium (Didronel) in the management of bone disease of multiple myeloma. International Workshop of Advances in Biology and Therapy of Myeloma, 1989.Blackstein M, Eisenhauer E, Wierzbicki R. Epirubicin in extensive small cell lung cancer: a phase II study in patients without prior chemotherapy. Proc.Am.Soc.Clin.Oncol, 1989.Eisenhauer E. Novel anticancer drugs in phase I development: the anthrapyrazoles and a diarylsulfonylurea. International Congress of Chemotherapy, 1989.Eisenhauer E, Evans W, Blackstein M. 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Phase II study of recombinant tumor necrosis factor (TNF) in renal cell carcinoma. Symposium on Immunobiology in Clinical Oncology, 1989.Zee B, Redmond C. Exact variance and simulation model for kappa statistic. Biometric Session in ASA and Biometrics Joint Statistical Meeting, 1989. 1988Eisenhauer E, Quirt I, Cairncross G, Iscoe N, Swenerton K. Phase II evaluation of trimetrexate in four solid tumors. Eur.Soc.Med.Oncol., 1988.Evans W, Eisenhauer E, Wierzbicki R, Kocha W, Wilson K, Murray N. A phase II trial of VP-16 and cisplatin in patients with unresectable mesothelioma. Ann.R.Coll.Phy.Surg.Can, 1988.Feld R, Pater J, Coy P. Restaging of responding patients with limited disease small cell lung cancer -- is it really necessary? Proc.Am.Soc.Clin.Oncol, 1988.Goodwin P, Feld R, Evans WK, Pater J. Cost-effectiveness of cancer chemotherapy: an economic evaluation of a Canadian randomized trial in small cell lung cancer. World Conference on Lung Cancer, 1988.Jaakkimainen L, Goodwin PJ, Pater J, Warde P, Rapp E. Combination chemotherapy for advanced non-small lung cancer -- effective but at what cost? Lung Cancer 4 (suppl), 1988.Johnston D, Bogues W. The innovative role of study coordinator in the Clinical Trials Group. Controlled Clin.Trials 9(3), 266, 1988.Koski B. The use of participant surveys in the estimation of annual accrual for four multicenter controlled clinical trials. Controlled Clin.Trials 9(3), 270, 1988.Louie T, Mandell L, Feld A, Chow A, Robson H, Bow E, Miedzinski L, Nicolle L, Rachlis A, Phaneuf D, Pater J. Multicenter comparison of aztreonam plus cloxacillin, aztreonam plus tobramycin or moxalactam plus tobramycin as empiric therapy of febrile neutropenic episodes. Interscience Conference on Antimicrobial Agents and Chemotherapy, 1988.Pater J. Designing clinical trials of anti-emetics: who should be studied and how? Emesis Symposium, Ottawa, 1988.Pater J, Johnston D, Bogues W. Multicentre antiemetic trials - the NCIC Clinical Trials Group experience. Emesis Symposium, Ottawa, 1988.Quirt I, Eisenhauer E, Knowling M, Warr D, Bramwell V, Rusthoven J, Wierzbicki R, Verma S. A phase II study of trimetrexate in metastatic soft tissue sarcoma: a cooperative study of the Canadian Sarcoma Group and the NCIC Clinical Trials Group. Proc.Am.Soc.Clin.Oncol, 1988. 1987Carmichael J, Shelley W, Kirk M, Krepart G, Levitt M, Fraser R, Roy M, Wilson K. Factors predictive of persistent disease in patients N.E.D. at the completion of a course of cisplatin containing chemotherapy. Gynecol.Oncol. 26, 416, 1987.Eisenhauer E, Pritchard K, Perrault D, Verma S, Pater J. Phase II study of intravenous menogaril as first line chemotherapy for patients with breast cancer. Proc.Am.Soc.Clin.Oncol. 6, 1987.Klaassen D, Shelley W, Starreveld A, Boyes D, Gerulath A, Levitt M, Fraser R, Carmichael J, Methot Y. Early stage ovarian cancer: a randomized clinical trial comparing whole abdominal radiotherapy, melphalan, and intraperitoneal chromic phosphate -- all programs included pelvic radiotherapy. Proc.Am.Soc.Clin.Oncol. 6, 117, 1987.Logan D, Perrault DJ, Eisenhauer E, Stewart D, White D. Phase I-II study of flutamide in metastatic breast cancer. Proc.Am.Soc.Clin.Oncol, 1987.Rapp E, Pater J, Willan A, Cormier Y, Murray N, Evans W, Hodson I, Clark D, Feld R, Arnold A, Ayoub J, Wilson K, Latreille J, Wierzbicki R, Hill DP. A comparison of best supportive care to two regimens of combination chemotherapy in the management of advanced non-small cell lung cancer. A report of a Canadian multicentre trial. Proc.Am.Soc.Clin.Oncol. 6, 168, 1987.Yelle L, Willan A, Pater J. Trial of chemotherapy and radiotherapy in advanced Hodgkin's disease. Clin.Invest.Med. 10(4), 1987. 1986Band P, Maroun J, Pritchard K, Coppin C, Wilson K, Eisenhauer E. Phase II study of lonidamine in advanced breast cancer. NCI Canada Clinical Trials Group. Proc.Am.Soc.Clin.Oncol, 1986.Band P, Weinerman B, Eisenhauer E, Murray N. Lonidamine, a new anticancer agent: overview of Canadian trials. International Cancer Congress, 1986.Eisenhauer E, Johnston JB, Barr R, Feldman L, Maksymiuk A, Scott G, Sutton D, Venner P, Walde D, Zaentz D. 2'-Deoxycoformycin (DCF) in hairy cell leukemia. NCI-EORTC Symposium on New Drugs in Cancer Therapy, 1986.Evans W, Murray N, Feld R, Coy P, Levitt M, MacDonald A, Cormier Y, Young V, Osoba D, Shelley W, Willan A. Canadian multicenter randomized trial comparing standard and alternating combination chemotherapy in extensive small cell lung cancer. Proc.Am.Soc.Clin.Oncol. 5, 169, 1986.Johnston J, Eisenhauer E, Barr R, Feldman L, Maksymiuk A, Scott G, Sutton D, Venner P, Walde D. 2'-deoxycoformycin in hairy cell leukemia: a Canadian phase II trial. Proc.Am.Soc.Clin.Oncol, 1986.Jolivet J, Landry L, Pinard MF, Eisenhauer E. Daily bolus x 9 trimetrexate: a phase I clinical pharmacokinetic and pharmacodynamic study. Proc.Am.Assoc.Cancer Res, 1986.Louie T, Mandell L, Feld R, Chow A, Robson H, Bow E, Miedzinski L, Nicolle L, Rachlis A, Phaneuf D, Pater J. Multicentre comparison of aztreonam plus cloxacillin, aztreonam plus tobramycin, or moxalactam plus tobramycin as empiric therapy of febrile neutropenic episodes. International Symposium on Infections in the Immunocompromised Host, 1986.O'Dwyer P, Eisenhauer E, Hoth D. Deoxycoformycin in lymphoid malignancies, an overview. NCI-EORTC Symposium on New Drugs in Cancer Therapy, 1986.Pater J, Elliott C. The effect of different measures of outcome on the results of studies of empiric antiobiotic therapy in febrile neutropenic patients. International Symposium on Infections in the Immunocompromised Host, 1986.Perrault DJ, Logan D, Bramwell V, Eisenhauer E, Pritchard K, Stewart D, White D. Phase I-II study of flutamide in metastatic breast cancer. Breast Cancer Research and Treatment 8, 90, 1986.Quirt I, Shelley W, Bodurtha A, McCulloch P, McPherson A, Paterson A, Prentice R, Silver H, Willan A, Wilson K. Adjuvant levamisole improves survival and disease-free survival in patients with poor prognosis malignant melanoma. Proc.Am.Soc.Clin.Oncol. 5, 130, 1986.Wallenstein S, Patel HI, Willan A. Use of baseline values in the two period two treatment crossover design. Biometric Society ENAR, 1986. 1985Belch A, White D, Bergsagel D, Wilson K, Shelley W. Remission duration in multiple myeloma. Proc.Am.Soc.Clin.Oncol. 4, 215, 1985.Feld R, Evans WK, Coy P, Hodson I, MacDonald AS, Osoba D, Payne DG, Pater JL. Canadian multicentre randomized trial comparing sequential and alternating administration of two non-cross resistant chemotherapy combinations in patients with limited small cell carcinoma of the lung. Proc.Am.Soc.Clin.Oncol. 4: 177, 1985.Osoba D, Erlichman C, Willan A, Levitt M, Pater J. Superiority of methylprednisolone sodium succinate over conventional dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy. Proc.Am.Soc.Clin.Oncol. 4, 268,1985.Pater JL, Willan AR, Erlichman C, Osoba D, Levitt M. A validation of self-reported measures of nausea and vomiting. Proc Am Soc Clin Oncol 4[abstr C-1032], 265, 1985.Pater J, Willan A, Erlichman C, Osoba D, Levitt M. A validation of self-reported measures of nausea and vomiting. Clin.Invest.Med. 8, 1985.Pritchard K, Meakin J, Sawka C, Thomson D, Myers R, Sutherland D, Mobbs B, Malkin A, Shelley W, Paterson A. The role and mechanism of action of tamoxifen in premenopausal women with metastatic carcinoma of the breast: an update. Proc.Am.Soc.Clin.Oncol. 4, 54, 1985.Willan A. Choosing the largest test statistic in the two-period crossover trial. American Statistical Association, 1985. 1984Belch A, White D, Bergsagel D, Wilson K, Shelley W, Koch M. Analysisof progression patterns of multiple myeloma. Ann.R.Coll.Phy.Surg.Can. 17, 343, 1984.Belch A, White D, Bergsagel D, Wilson K, Shelley W. The role of maintenance chemotherapy for multiple myeloma. Proc.Am.Soc.Clin.Oncol. 3, 268, 1984.Bow E, et al. The effect of prophylactic antibiotics on outcome of infection in granulocytopenic patients receiving trimethoprim/sulfamethoxazole. International Symposium on Infections in the Immunocompromised Host, 1984.Maroun J, Maksymiuk A, Eisenhauer E, Stewart D, Young V, Pater J. A phase II trial of acivicin (AT-125, NSC 163501) (A) in metastatic non-small cell lung cancer. A Canadian National Cancer Institute Study. Proc.Am.Soc.Clin.Oncol. 3, 1984.Pater J, Louie T, Mandell L, et al. Factors influencing outcomes of febrile episodes in granulocytopenic patients -- a multivariate analysis. Internation Symposium on Infections in the Immunocompromised Host, 1984.Pater J, Shelley W, Willan A, Kirk M, Carmichael J, Krepart G, Levitt M, Roy M. The effect of histologic subtype, grade and residual tumor diameter on survival and negative second look rates in patients with Stage III and IV carcinoma of the ovary. Proc.Am.Soc.Clin.Oncol. 3, 166, 1984.Quirt I, Shelley W, Bodurtha A, McCulloch P, McPherson A, Paterson A, Prentice R, Silver H, Wilson K. A controlled trial of adjuvant immunotherapy for malignant melanoma. Proc.Am.Soc.Clin.Oncol. 3, 48, 1984.Weinerman B, Eisenhauer E, Maroun J, Coppin C, Armitage G. Phase II evaluation of lonidamine in advanced renal cell carcinoma. Proc.Am.Soc.Clin.Oncol 3, 1984.Willan A, Pater J. Carryover and the two-period crossover clinical trial. International Biometric Conference, 1984.Willan A, Pater J. Using baseline measurements to eliminate carryover in the two- period crossover clinical trial. Presented: 12th International Biometric Conference, 1984.Willan A, Pater J. Carryover and the two-period crossover clinical trial. American Statistical Association, 1984. 1983Feld R, Louie TJ, Mandell L, Robson H, Chow A, Bow E, Belch A, Goldsand G, Pater J. A multicentre comparative trial of moxalactam and ticarcillin vs tobramycin and ticarcillin in febrile neutropenic patients. Proc.Am.Soc.Clin.Oncol. 2, 87, 1983.Feld R, et al. The use of combination beta-lactam therapy in febrile neutropenic patients. International Conference of Chemotherapy, 1983.Mandell L, Louie T, Feld R, et al. A prospective randomized trial of ticarcillin and tobramycin in the treatment of febrile neutropenic patients. International Conference of Chemotherapy, 1983.Willan A, Pater J. The mixed benefits of subtracting baseline measurements in crossover trials. Clin.Invest.Med. 6 (Suppl 2), 49, 1983. 1981Belch A, Ronald AR, Feld R, Pater J. Efficacy of lithium during remission induction of acute myelogenous leukemia (AML). Blood (ASH Annual Meeting Abstracts) 58[5 Suppl, abstr 447], 1981.White D, Bergsagel D, Rapp E, Khaliq A, Shelley W, Pater J. Failure of cyclophosphamide to produce response in melphalan resistant multiple myeloma. Blood (ASH Annual Meeting Abstracts) 58[5 Suppl 1, abstr 586], 1981.
