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CCTG Connection



Published:
Category: News
Dr. Cheung and Dr. Hay receive bridge funding - CIHR Spring 2020 competition

Congratulations to Dr. Annette Hay, a Senior Investigator with the Canadian Cancer Trials Group and Dr. Matthew Cheung, Hematologist at Sunnybrook Health Sciences Centre. Together they received an additional $100,000 in bridge funding in the Canadian Institutes of Health Research (CIHR) Fall 2020 competition matching funds awarded in the spring from this program designed to capture and support ideas with the greatest potential to advance health-related knowledge in Canada. 

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Published:
Category: News
Health Insight news story on the IC8 study
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Published:
Category: Group updates
CCTG is hiring: Study Coordinator

The Cancer Research Study Coordinator works within a team based structure to coordinate and oversee national, international and cooperative oncology group, multi-centre, multi-modality clinical trials in cancer therapy, prevention and supportive care.

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Published:
Category: Publications
QoL publications
  1. Quantile regression and empirical likelihood for the analysis of longitudinal data with monotone missing responses due to dropout, with applications to quality of life measurements from clinical trials.
  2. A threshold linear mixed model for identification of treatment-sensitive subsets in a clinical trial based on longitudinal outcomes and a continuous covariate.
  3. Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial.
  4. Joint analysis of longitudinal measurements and survival times with a cure fraction based on partly linear mixed and semiparametric cure models
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Published:
Category: Trials
Trial Milestone: MA36 (OlympiA)

OlympiA: A randomised, double-blind, parallel group, placebo-controlled multi-centre Phase III study to assess the efficacy and safety of olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy.

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Published:
Category: News

The Toronto International Sarcoma Symposium 2021 (virtual format) is just around the corner!

This multidisciplinary symposium will be held on April 09, 2021, and includes speakers and participants from Canada as well as from the International Sarcoma community. The keynote speakers are Dr. Andrew Wagner (Dana Farber) and Dr. David Kirsch (Duke). The one day symposium will feature Clinical and Translational Research among other topics, please see the program page for details.

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Published:
Category: Trials

The CCTG CO29 (AGITG CTDNA-08) - Circulating Tumor DNA Analysis Informing Adjuvant Chemotherapy in Stage III Colon Cancer: A Multi-centre Phase II/III Randomised Controlled Study (DYNAMIC III) has been centrally activated.

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Published:
Category: Group updates

CCTG is delighted to announce that Dr. Alexander Wyatt has become the new Correlative Sciences Committee Chair for the CCTG GU disease site committee.

Dr.  Wyatt is an Assistant Professor in Urologic Sciences at the University of British Columbia, a Senior Research Scientist at the Vancouver Prostate Centre, and Scientist at the BC Cancer Genome Sciences Centre. He has a PhD in genetics (University of Oxford), and now specializes in human genitourinary cancer genomics and bio informatics

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