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CCTG Connection



Published:
Category: Publications
Two new guidance publications: Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance and Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. Read More

Published:
Category: Publications

Results from a phase III international study (IND.227) were recently published in The Lancet  and evaluated the use of the immunotherapy drug pembrolizumab combined with platinum-pemetrexed chemotherapy. Researchers conclude that as a first-line treatment for patients with unresectable advanced or metastatic pleural mesothelioma, pembrolizumab plus platinum-pemetrexed chemotherapy represents a new treatment option for patients.

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Published:
Category: Trials
IND.244 - A Phase 2 Study of Ibrutinib Combination Therapy in Transplant Ineligible Individuals with Newly Diagnosed Primary Central Nervous System Lymphoma has been centrally activated. Read More



Published:
Category: Group updates

The Pharmacy Network is actively seeking volunteers for Disease Site Representative positions in both Gastrointestinal and Lung.  

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Published:
Category: Group updates
Honouring Patient Representative Sylvie Desmarais

It is with great sadness that we acknowledge the passing of CCTG Patient Representative Sylvie Desmarais, after her four year battle with metastatic breast cancer. Her main mission was as a patient partner, supporting the advancement of research and services for women with breast cancer.

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Published:
Category: News
2023 Practicum Central Office Visit

Congrats to the 2023-2024 Practicum participant who successfully completed their in person visit to CCTG Central Offices in Kingston, Ontario October 5th 6th, 2023. During their visit the group participated in the following sessions:

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Published:
Category: Publications
Publications from CRC6 (NCT01150045) Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
 
Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance).
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Published:
Category: Publications
The results of CCTG BR36 trial, recently published in the journal Nature Medicine, suggest that circulating tumor DNA (ctDNA) analyses could be used as an early marker of immunotherapy response and may help guide therapy. Read More