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Journal Publications

 

 
 
  • Battaglin F, Ou F-S, Qu X, Hochster HS, Niedzwiecki D, Goldberg RM, Mayer RJ, Ashouri K, Zemla TJ, Blanke CD, Venook AP, Kabbarah O, Lenz H-J, Innocenti F. HER2 Gene Expression Levels Are Predictive and Prognostic in Patients With Metastatic Colorectal Cancer Enrolled in CALGB/SWOG 80405 (ONLINE). Journal of Clinical Oncology 2024.
  • Ganz PA, Bandos H, Španić T, Friedman S, Müller V, Kuemmel S, Delaloge S, Brain E, Toi M, Yamauchi H, de Dueñas E-M, Armstrong A, Im S-A, Song C-g, Zheng H, Sarosiek T, Sharma P, Geng C, Fu P, Rhiem K, Frauchiger-Heuer H, Wimberger P, t'Kint de Roodenbeke D, Liao N, Goodwin A, Chakiba-Brugère C, Friedlander M, Lee KS, Giacchetti S, Takano T, Henao-Carrasco F, Virani S, Valdes-Albini F, Domchek SM, Bane C, McCarron EC, Mita M, Rossi G, Rastogi P, Fielding A, Gelber RD, Scheepers ED, Cameron D, Garber J, Geyer CE, Tutt ANJ. Patient-Reported Outcomes in OlympiA: A Phase III, Randomized, Placebo-Controlled Trial of Adjuvant Olaparib in gBRCA1/2 Mutations and High-Risk Human Epidermal Growth Factor Receptor 2–Negative Early Breast Cancer (ONLINE). Journal of Clinical Oncology 2024.
  • Garcia-Manero G, Podoltsev NA, Othus M, Pagel JM, Radich JP, Fang M, Rizzieri DA, Marcucci G, Strickland SA, Litzow MR, Savoie ML, Medeiros BC, Sekeres MA, Lin TL, Uy GL, Powell BL, Kolitz JE, Larson RA, Stone RM, Claxton D, Essell J, Luger SM, Mohan SR, Moseley A, Appelbaum FR, Erba HP. A randomized phase III study of standard versus high-dose cytarabine with or without vorinostat for AML. Leukemia 38: 58-66. 2024.
  • Kerba M, Lourenco RDA, Sahgal A, Cardet RdF, Siva S, Ding K, Myrehaug S, Masucci GL, Brundage M, Parulekar WR. An Economic Analysis of SC24 in Canada: A Randomized Study of SBRT Compared with Conventional Palliative RT for Spinal Metastases (ONLINE). International Journal of Radiation Oncology*Biology*Physics 2024.
  • Nicolle R, Bachet J-B, Harlé A, Iovanna J, Hammel P, Rebours V, Turpin A, Abdelghani MB, Wei A, Mitry E, Lopez A, Biagi J, François E, Artru P, Lambert A, Renouf DJ, Monard L, Mauduit M, Dusetti N, Conroy T, Cros J. Prediction of Adjuvant Gemcitabine Sensitivity in Resectable Pancreatic Adenocarcinoma Using the GemPred RNA Signature: An Ancillary Study of the PRODIGE-24/CCTG PA6 Clinical Trial. Journal of Clinical Oncology 42: 1067-1076. 2024.
  • Plante M, Kwon JS, Ferguson S, Samouëlian V, Ferron G, Maulard A, de Kroon C, Van Driel W, Tidy J, Williamson K, Mahner S, Kommoss S, Goffin F, Tamussino K, Eyjólfsdóttir B, Kim J-W, Gleeson N, Brotto L, Tu D, Shepherd LE. Simple versus Radical Hysterectomy in Women with Low-Risk Cervical Cancer. New England Journal of Medicine 390: 819-829. 2024.
  • Solar Vasconcelos JP, Chen N, Titmuss E, Tu D, Brule SY, Goodwin R, Jonker DJ, Price T, Zalcberg JR, Moore MJ, Karapetis CS, Siu L, Shapiro J, Simes J, Gill S, O'Callaghan CJ, Loree JM. Transverse colon primary tumor location as a biomarker in metastatic colorectal cancer: A pooled analysis of CCTG/AGITG CO.17 and CO.20 randomized clinical trials (ONLINE). Clinical Cancer Research 2024.
  • Stinchcombe TE, Wang X, Damman B, Mentlick J, Landreneau R, Wigle D, Jones DR, Conti M, Ashrafi AS, Liberman M, de Perrot M, Mitchell JD, Keenan R, Bauer T, Miller D, Altorki N. Secondary Analysis of the Rate of Second Primary Lung Cancer From Cancer and Leukemia Group B 140503 (Alliance) Trial of Lobar Versus Sublobar Resection for T1aN0 Non–Small-Cell Lung Cancer (ONLINE). Journal of Clinical Oncology 2024.
  • Altorki N, Wang X, Kozono D, Watt C, Landrenau R, Wigle D, Port J, Jones DR, Conti M, Ashrafi AS, Liberman M, Yasufuku K, Yang S, Mitchell JD, Pass H, Keenan R, Bauer T, Miller D, Kohman LJ, Stinchcombe TE, Vokes E. Lobar or Sublobar Resection for Peripheral Stage IA NonSmall-Cell Lung Cancer. N Engl J Med 388: 489-98, 2023.
  • Anagnostou V, Ho C, Nicholas G, Juergens RA, Sacher A, Fung AS, Wheatley-Price P, Laurie SA, Levy B, Brahmer JR, Balan A, Niknafs N, Avrutin E, Zhu L, Sausen M, Bradbury PA, O’Donnell-Tormey J, Gaudreau PO, Ding K, Dancey J. ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results. Nature Medicine 29: 2559-2569. 2023.
  • Araujo D, Greystoke A, Bates S, Bayle A, Calvo E, Castelo-Branco L, de Bono J, Drilon A, Garralda E, Ivy P, Kholmanskikh O, Melero I, Pentheroudakis G, Petrie J, Plummer R, Ponce S, Postel-Vinay S, Siu L, Spreafico A, Stathis A, Steeghs N, Yap C, Yap TA, Ratain M, Seymour L. Oncology phase I trial design and conduct: time for a change - MDICT Guidelines 2022. Ann Oncol 34: 48-60, 2023.
  • Ashok Kumar P, Karimi M, Basnet A, Seymour L, Kratzke R, Brambilla E, et al. Association of Molecular Profiles and Mutational Status With Distinct Histological Lung Adenocarcinoma Subtypes. An Analysis of the LACE-Bio Data. Clin Lung Cancer. 24: 528-40, 2023.
  • Assouline S, Michaelis LC, Othus M, Hay AE, Walter RB, Jacoby MA, Schroeder MA, Uy GL, Law LY, Cheema F, Sweet KL, Asch AS, Liu J, Moseley AB, Maher T, Kingsbury LL, Fang M, Radich J, Little RF, Erba HP. A randomized phase II/III study of 'novel therapeutics' versus azacitidine in newly diagnosed patients with acute myeloid leukemia (AML), high-risk myelodysplastic syndrome (MDS), or chronic myelomonocytic leukemia (CMML), age 60 or older: a report of the comparison of azacitidine and nivolumab to azacitidine: SWOG S1612. Leuk Lymphoma 64: 473-7, 2023.
  • Basch E, Dueck AC, Mitchell SA, Mamon H, Weiser M, Saltz L, et al. Patient-Reported Outcomes During and After Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048). Journal of Clinical Oncology. 41: 3724-34, 2023.
  • Black PC, Tangen CM, Singh P, McConkey DJ, Lucia MS, Lowrance WT, Koshkin VS, Stratton KL, Bivalacqua TJ, Kassouf W, Porten SP, Bangs R, Plets M, Thompson IM, Lerner SP. Phase 2 Trial of Atezolizumab in Bacillus Calmette-Guérin–unresponsive High-risk Non–muscle-invasive Bladder Cancer: SWOG S1605. European Urology 84: 536-544. 2023.
  • Boutin M, Topham JT, Feilotter H, Kennecke HF, Couture F, Harb M, et al. Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer (ONLINE). Therapeutic Advances in Medical Oncology 15: 17588359231183682. 2023.
  • Brown JC, Ma C, Shi Q, Fuchs CS, Meyer J, Niedzwiecki D, Zemla T, Couture F, Kuebler P, Kumar P, Lewis D, Tan B, Krishnamurthi S, O'Reilly EM, Shields AF, Meyerhardt JA. Physical Activity in Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance). J Clin Oncol 41: 243-54, 2023.
  • Chen EX, Loree JM, Titmuss E, Jonker DJ, Kennecke HF, Berry S, Couture F, Ahmad CE, Goffin JR, Kavan P, Harb M, Colwell B, Samimi S, Samson B, Abbas T, Aucoin N, Aubin F, Koski S, Wei AC, Tu D, O’Callaghan CJ. Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Network Open 6: e2346094-e2346094. 2023.
  • Chi M, Wang X, Song H, Peng Y, Tu D. Joint Analysis of Longitudinal Ordinal Categorical Item Response Data and Survival Times with Cure Fraction (ONLINE). Statistics in Biopharmaceutical Research 1-11. 2023.
  • Chu Q, Perrone F, Greillier L, Tu W, Piccirillo MC, Grosso F, Lo Russo G, Florescu M, Mencoboni M, Morabito A, Cecere FL, Ceresoli GL, Dawe DE, Zucali PA, Pagano M, Goffin JR, Sanchez ML, Gridelli C, Zalcman G, Quantin X, Westeel V, Gargiulo P, Delfanti S, Tu D, Lee CW, Leighl N, Sederias J, Brown-Walker P, Luo Y, Lantuejoul S, Tsao M-S, Scherpereel A, Bradbury P, Laurie SA, Seymour L. Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label, randomised controlled trial. The Lancet 402: 2295-2306. 2023.
  • Connolly RM, Miller KD. Back to the Beginning: The Role of Ovarian Suppression in Management of Hormone Sensitive Breast Cancer in Premenopausal Women. J Clin Oncol 41: 1339-41, 2023.
  • Deng Y, Tu D, O'Callaghan CJ, Jonker DJ, Karapetis CS, Shapiro J, Liu G, Xu W. A Bayesian approach for two-stage multivariate Mendelian randomization with mixed outcomes. Statist Med, 42: 2241-2256. 2023.
  • Deng Y, Tu D, O'Callaghan CJ, Liu G, Xu W. Two-stage multivariate Mendelian randomization on multiple outcomes with mixed distributions. Statistical Methods in Medical Research 32: 1543-1558. 2023.
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100,000 women from 86 randomised trials. The Lancet 401: 1277-92, 2023.
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Radiotherapy to regional nodes in early breast cancer: an individual patient data meta-analysis of 14,324 women in 16 trials. The Lancet 402: 1991-2003. 2023.
  • Eskander RN, Sill MW, Beffa L, Moore RG, Hope JM, Musa FB, Mannel R, Shahin MS, Cantuaria GH, Girda E, Mathews C, Kavecansky J, Leath CA, Gien LT, Hinchcliff EM, Lele SB, Landrum LM, Backes F, O'Cearbhaill RE, Al Baghdadi T, Hill EK, Thaker PH, John VS, Welch S, Fader AN, Powell MA, Aghajanian C. Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer. N Engl J Med 388: 2159-70, 2023.
  • Everest L, Chen BE, Hay AE, Cheung MC, Chan KKW. Power and sample size calculation for incremental net benefit in cost effectiveness analyses with applications to trials conducted by the Canadian Cancer Trials Group. BMC Medical Research Methodology 23: 179, 2023.
  • Francis PA, Fleming GF, Láng I, Ciruelos EM, Bonnefoi HR, Bellet M, Bernardo A, Climent MA, Martino S, Bermejo B, Burstein HJ, Davidson NE, Geyer CE, Walley BA, Ingle JN, Coleman RE, Müller B, Le Du F, Loibl S, Winer EP, Ruepp B, Loi S, Colleoni M, Coates AS, Gelber RD, Goldhirsch A, Regan MM. Adjuvant Endocrine Therapy in Premenopausal Breast Cancer: 12-Year Results From SOFT. J Clin Oncol 41: 1370-5, 2023.
  • Garralda E, Laurie SA, Seymour L, de Vries EGE. Towards evidence-based response criteria for cancer immunotherapy. Nat Commun. 14: 3001, 2023.
  • Goodwin PJ, Chen BE, Gelmon KA, Whelan TJ, Ennis M, Lemieux J, Ligibel JA, Hershman DL, Mayer IA, Hobday TJ, Bliss JM, Rastogi P, Rabaglio-Poretti M, Thompson AM, Rea DW, Stos PM, Shepherd LE, Stambolic V, Parulekar WR. Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer. Journal of Clinical Oncology 41: 5356-5362. 2023.
  • Gupta A, Hay AE, Crump M, Djurfeldt MS, Zhu L, Cheung MC, Shepherd LE, Chen BE, Booth CM. Contact Days Associated With Cancer Treatments in the CCTG LY.12 Trial. The Oncol, 28: 799-803. 2023.
  • Gupta A, O'Callaghan CJ, Zhu L, Jonker DJ, Wong RPW, Colwell B, et al. Evaluating the Time Toxicity of Cancer Treatment in the CCTG CO.17 Trial. JCO Oncol Pract. 19: e859-e66, 2023.
  • Hanna L, Moffat GT, Hopman W, Gaudreau PO, Fung AS. A study of the efficacy and toxicity outcomes of extended durvalumab dosing in patients with stage III unresectable non-small cell lung cancer (NSCLC) during the COVID-19 pandemic (ONLINE). Cancer Treatment and Research Communications 34: 100678, 2023.
  • Hilton LK, Ngu HS, Collinge B, Dreval K, Ben-Neriah S, Rushton CK, Wong JCH, Cruz M, Roth A, Boyle M, Meissner B, Slack GW, Farinha P, Craig JW, Gerrie AS, Freeman CL, Villa D, Rodrigo JA, Song K, Crump M, Shepherd L, Hay AE, Kuruvilla J, Savage KJ, Kridel R, Karsan A, Marra MA, Sehn LH, Steidl C, Morin RD, Scott DW. Relapse Timing Is Associated With Distinct Evolutionary Dynamics in Diffuse Large B-Cell Lymphoma. Journal of Clinical Oncology 41: 4164-4177. 2023.
  • Huntoon K, Anderson SK, Ballman KV, Twohy E, Dooley K, Jiang W, An Y, Li J, von Roemeling C, Qie Y, Ross OA, Cerhan JH, Whitton AC, Greenspoon JN, Parney IF, Ashman JB, Bahary J-P, Hadjipanayis C, Urbanic JJ, Farace E, Khuntia D, Laack NN, Brown PD, Roberge D, Kim BYS. Association of circulating markers with cognitive decline after radiation therapy for brain metastasis. Neuro-Oncology 25: 1123-1131. 2023.
  • Jiang DM, Parshad S, Zhan L, Sim H-W, Siu LL, Liu G, Shapiro JD, Price TJ, Jonker DJ, Karapetis CS, Strickland AH, Zhang W, Jeffery M, Tu D, Ng S, Sabesan S, Shannon J, Townsend A, O'Callaghan CJ, Chen EX. Plasma Cetuximab Concentrations Correlate With Survival in Patients With Advanced KRAS Wild Type Colorectal Cancer. Clinical Colorectal Cancer 22: 457-463. 2023.
  • Johnson PC, Woyach JA, Ulrich A, Marcotte V, Nipp RD, Lage DE, Nelson AM, Newcomb RA, Rice J, Lavoie MW, Ritchie CS, Bartlett N, Stephens DM, Ding W, Owen C, Stone R, Ruppert AS, Mandrekar SJ, Byrd JC, El-Jawahri A, Le-Rademacher J, Rosko A. Geriatric assessment measures are predictive of outcomes in chronic lymphocytic leukemia. Journal of Geriatric Oncology 14: 101538. 2023.
  • Karamouza E, Glasspool RM, Kelly C, Lewsley LA, Carty K, Kristensen GB, Ethier JL, Kagimura T, Yanaihara N, Cecere SC, You B, Boere IA, Pujade-Lauraine E, Ray-Coquard I, Proust-Lima C, Paoletti X. CA-125 Early Dynamics to Predict Overall Survival in Women with Newly Diagnosed Advanced Ovarian Cancer Based on Meta-Analysis Data. Cancers 15: 1823, 2023.
  • Kayton ML, Weiss AR, Xue W, Binitie O, Hayes Dixon A, Randall RL, Sorger JI, Hawkins DS, Spunt SL, Wang D, Million L, Terezakis S, Choy E, Okuno SH, Venkatramani R, Chen Y-L, Scharschmidt TJ. Neoadjuvant pazopanib in nonrhabdomyosarcoma soft tissue sarcomas (ARST1321): A report of major wound complications from the Children's Oncology Group and NRG Oncology. Journal of Surgical Oncology 127: 871-881. 2023.
  • Kennecke HF, O'Callaghan CJ, Loree JM, Moloo H, Auer R, Jonker DJ, Raval M, Musselman R, Ma G, Caycedo-Marulanda A, Simianu VV, Patel S, Pitre LD, Helewa R, Gordon VL, Neumann K, Nimeiri H, Sherry M, Tu D, Brown CJ. Neoadjuvant Chemotherapy, Excision, and Observation for Early Rectal Cancer: The Phase II NEO Trial (CCTG CO.28) Primary End Point Results. J Clin Oncol 41: 233-42, 2023.
  • Lee S, Ma C, Shi Q, Kumar P, Couture F, Kuebler P, Krishnamurthi S, Lewis D, Tan B, Goldberg RM, Venook A, Blanke C, O'Reilly EM, Shields AF, Meyerhardt JA. Potential Mediators of Oxaliplatin-Induced Peripheral Neuropathy From Adjuvant Therapy in Stage III Colon Cancer: Findings From CALGB (Alliance)/SWOG 80702. Journal of Clinical Oncology 41: 1079-1091. 2023.
  • Lee S, Ma C, Shi Q, Meyers J, Kumar P, Couture F, Kuebler P, Krishnamurthi S, Lewis D, Tan B, O’Reilly EM, Shields AF, Meyerhardt JA. Sleep and cancer recurrence and survival in patients with resected Stage III colon cancer: findings from CALGB/SWOG 80702 (Alliance). British Journal of Cancer 129: 283-290. 2023.
  • Li N, Song Y, Lin CD, Tu D. Bootstrap adjusted predictive classification for identification of subgroups with differential treatment effects under generalized linear models (ONLINE). Electronic Journal of Statistics 17: 548-606, 2023.
  • Li N, Song Y, Lin CD, Tu D. Bootstrap Adjustment to Minimum p-Value Method for Predictive Classification. Statistica Sinica 33: 2065-2086, 2023.
  • Luen SJ, Viale G, Nik-Zainal S, Savas P, Kammler R, Dell'Orto P, Biasi O, Degasperi A, Brown LC, Láng I, MacGrogan G, Tondini C, Bellet M, Villa F, Bernardo A, Ciruelos E, Karlsson P, Neven P, Climent M, Müller B, Jochum W, Bonnefoi H, Martino S, Davidson NE, Geyer C, Chia SK, Ingle JN, Coleman R, Solbach C, Thürlimann B, Colleoni M, Coates AS, Goldhirsch A, Fleming GF, Francis PA, Speed TP, Regan MM, Loi S. Genomic characterisation of hormone receptor-positive breast cancer arising in very young women. Ann Oncol 34: 397-409, 2023.
  • Lukovic J, Moore AJ, Lee MT, Willis D, Ahmed S, Akra M, Hortobagyi E, Kron T, Lim Joon D, Liu A, Ryan J, Thomas M, Wall K, Ward I, Wiltshire KL, O'Callaghan CJ, Wong RKS, Ringash JG, Haustermans K, Leong T. The Feasibility of Quality Assurance in the TOPGEAR International Phase III Clinical Trial of Neoadjuvant Chemoradiotherapy for Gastric Cancer (An Intergroup Trial of the AGITG/TROG/NHMRC CTC/EORTC/CCTG) International Journal of Radiation Oncology*Biology*Physics 117: 1096-1106. 2023.
  • Mian H, Ringash J, Meyer R, Hay AE, Shepherd L, Djurfeldt M, Winter JN, Sussman J, Pater J, Chen BE, Prica A. Health-related quality of life in early-stage Hodgkin lymphoma: a longitudinal analysis of the ABVD arm in the randomized controlled trial HD.6. Supportive Care in Cancer 31: 256, 2023.
  • Morris MJ, Heller G, Hillman DW, Bobek O, Ryan C, Antonarakis ES, et al. Randomized Phase III Study of Enzalutamide Compared With Enzalutamide Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer (Alliance A031201 Trial). J Clin Oncol. 41: 3352-62, 2023.
  • Nohová I, Andrews J, Votan B, Miller A, Sehouli J, Berger R. Patient involvement in research within the Gynecological Cancer InterGroup: A call to action for a systematic approach: Results from a survey. Health Science Reports 6: e1735. 2023.
  • Othus M, Thomas I, Wang X, Ariti C, Mehta P, Sydenham M, Hills RK, Burnett AK, Nand S, Assouline S, Michaelis LC, Erba HP, Russell N, Kerr KF, Walter RB, Dennis M. Early mortality risk with non-intensive acute myeloid leukemia (AML) therapies: analysis of 1336 patients from MRC/NCRI and SWOG. Leuk Lymphoma 64: 250-2, 2023.
  • Pagani O, Walley BA, Fleming GF, Colleoni M, Láng I, Gomez HL, Tondini C, Burstein HJ, Goetz MP, Ciruelos EM, Stearns V, Bonnefoi HR, Martino S, Geyer CE, Chini C, Puglisi F, Spazzapan S, Ruhstaller T, Winer EP, Ruepp B, Loi S, Coates AS, Gelber RD, Goldhirsch A, Regan MM, Francis PA. Adjuvant Exemestane With Ovarian Suppression in Premenopausal Breast Cancer: Long-Term Follow-Up of the Combined TEXT and SOFT Trials. J Clin Oncol 41: 1376-82, 2023.
  • Partridge AH, Niman SM, Ruggeri M, Peccatori FA, Azim HA, Colleoni M, Saura C, Shimizu C, Sætersdal AB, Kroep JR, Mailliez A, Warner E, Borges VF, Amant F, Gombos A, Kataoka A, Rousset-Jablonski C, Borstnar S, Takei J, Lee JE, Walshe JM, Ruíz-Borrego M, Moore HCF, Saunders C, Bjelic-Radisic V, Susnjar S, Cardoso F, Smith KL, Ferreiro T, Ribi K, Ruddy K, Kammler R, El-Abed S, Viale G, Piccart M, Korde LA, Goldhirsch A, Gelber RD, Pagani O. Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer. N Engl J Med 388: 1645-56, 2023.
  • Pe M, Alanya A, Falk RS, Amdal CD, Bjordal K, Chang J, Cislo P, Coens C, Dirven L, Speck RM, Fitzgerald K, Galinsky J, Giesinger JM, Holzner B, Le Cessie S, O'Connor D, Oliver K, Pawar V, Quinten C, Schlichting M, Ren J, Roychoudhury S, Taphoorn MJB, Velikova G, Wintner LM, Griebsch I, Bottomley A; SISAQOL-IMI Consortium. Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints in Cancer Clinical Trials-Innovative Medicines Initiative (SISAQOL-IMI): stakeholder views, objectives, and procedures. Lancet Oncol 24: e270-e283. 2023.
  • Petersen PM, Cook AD, Sydes MR, Clarke N, Cross W, Kynaston H, Logue J, Neville P, Payne H, Parmar MKB, Parulekar W, Persad R, Saad F, Stirling A, Parker CC, Catton C. Salvage Radiation Therapy After Radical Prostatectomy: Analysis of Toxicity by Dose-Fractionation in the RADICALS-RT Trial. International Journal of Radiation Oncology*Biology*Physics 117: 624-629. 2023.
  • Pfeiler G, Hlauschek D, Mayer EL, Deutschmann C, Kacerovsky-Strobl S, Martin M, Meisel JL, Zdenkowski N, Loibl S, Balic M, Park H, Prat A, Isaacs C, Bajetta E, Balko JM, Bellet-Ezquerra M, Bliss J, Burstein H, Cardoso F, Fohler H, Foukakis T, Gelmon KA, Goetz M, Haddad TC, Iwata H, Jassem J, Lee S-C, Linderholm B, Los M, Mamounas EP, Miller KD, Morris PG, Munzone E, Gal-Yam EN, Ring A, Shepherd L, Singer C, Thomssen C, Tseng L-M, Valagussa P, Winer EP, Wolff AC, Zoppoli G, Machacek-Link J, Schurmans C, Huang X, Gauthier E, Fesl C, Dueck AC, DeMichele A, Gnant M, Investigators obotPG, Cameron D, El-Abed S, Rugo HS, Steger GG, Traina T, Werutsky G, Wolmark N. Impact of BMI in Patients With Early Hormone Receptor–Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial. Journal of Clinical Oncology 41: 5118-5130. 2023.
  • Piccirillo MC, Chu Q, Bradbury P, Seymour L. Response to a Letter Received Entitled: "'Brief Report: Canadian Cancer Trials Group IND.227': Unpacking the Clinical Potential of Single-Agent Pembrolizumab in Advanced Malignant Pleural Mesothelioma". J Thoracic Oncol 18: e68-e69, 2023.
  • Piccirillo MC, Chu Q, Bradbury P, Tu W, Coschi C, Grosso F, Florescu M, Mencoboni M, Goffin JR, Pagano M, Ciardiello F, Cecere FL, Vincent M, Ferrara R, Dawe DE, Hao D, Lee CW, Morabito A, Gridelli C, Cavanna L, Iqbal M, Blais N, Leighl NB, Wheatley-Price P, Tsao MS, Ugo F, El-Osta H, Gargiulo P, Gaudreau PO, Tu D, Sederias J, Brown-Walker P, Perrone F, Seymour L, Laurie SA. Brief Report: Canadian Cancer Trials Group IND.227: A Phase 2 Randomized Study of Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma (NCT02784171). J Thoracic Oncol 18: 813-9, 2023.
  • Rattner JI, Kopciuk KA, Vogel HJ, Tang PA, Shapiro JD, Tu D, Jonker DJ, Siu LL, O'Callaghan CJ, Bathe OF. Clinical and metabolomic characterization of Brivanib-Induced hypertension in metastatic colorectal cancer Cancer Medicine 12: 16019-16031. 2023.
  • Shankar LK, Huang E, Litière S, Hoekstra OS, Schwartz L, Collette S, Boellaard R, Bogaerts J, Seymour L, de Vries EGE. Meta-Analysis of the Test-Retest Repeatability of [18F]-Fluorodeoxyglucose Standardized Uptake Values: Implications for Assessment of Tumor Response. Clin Cancer Res 29: 143-53, 2023.
  • Speers CW, Symmans WF, Barlow WE, Trevarton A, The S, Du L, Rae JM, Shak S, Baehner R, Sharma P, Pusztai L, Hortobagyi GN, Hayes DF, Albain KS, Godwin A, Thompson A. Evaluation of the Sensitivity to Endocrine Therapy Index and 21-Gene Breast Recurrence Score in the SWOG S8814 Trial. J Clin Oncol 41: 1841-8, 2023.
  • Sundquist S, Kato D, Chowdhury R, Samara C, Dancey JE. Minding the gaps: Assessing and addressing clinical research core competencies across a network of Canadian cancer centres (ONLINE). Frontiers in Pharmacology 14: 1294335. 2023.
  • Sweeney CJ, Martin AJ, Stockler MR, Begbie S, Cheung L, Chi KN, Chowdhury S, Frydenberg M, Horvath LG, Joshua AM, Lawrence NJ, Marx G, McCaffrey J, McDermott R, McJannett M, North SA, Parnis F, Parulekar W, Pook DW, Reaume MN, Sandhu SK, Tan A, Tan TH, Thomson A, Vera-Badillo F, Williams SG, Winter D, Yip S, Zhang AY, Zielinski RR, Davis ID, Abdi E, Allan S, Bastick P, Begbie S, Blum R, Briscoe K, Brungs D, Bydder S, Chittajallu BR, Cronk M, Cuff K, Davis ID, Dowling A, Frydenberg M, George M, Horvath L, Hovey E, Joshua A, Karanth N, Kichenadasse G, Krieger L, Marx G, Mathlum M, Nott L, Otty Z, Parnis F, Pook D, Sandhu S, Sewak S, Stevanovic A, Stockler M, Suder A, Tan H, Torres J, Troon S, Underhill C, Weickhardt A, Zielinski R, Abbas T, Anan G, Booth C, Campbell H, Chi K, Chin J, Chouinard E, Donnelly B, Drachenberg D, Faghih A, Finelli A, Hotte S, Noonan K, North S, Rassouli M, Reaume N, Rendon R, Saad F, Sadikov E, Vigneault E, Zalewski P, McCaffrey J, McDermott R, Morris P, O'Connor M, Donnellan P, O'Donnell D, Edwards J, Fong P, Tan A, Chowdhury S, Crabb S, Khan O, Khoo V, Macdonald G, Payne H, Robinson A, Shamash J, Staffurth J, Thomas C, Thomson A, Sweeney CJ. Testosterone suppression plus enzalutamide versus testosterone suppression plus standard antiandrogen therapy for metastatic hormone-sensitive prostate cancer (ENZAMET): an international, open-label, randomised, phase 3 trial. The Lancet Oncology 24: 323-34, 2023.
  • Topham JT, O'Callaghan CJ, Feilotter H, Kennecke HF, Lee YS, Li W, Banks KC, Quinn K, Renouf DJ, Jonker DJ, Tu D, Chen EX, Loree JM. Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer. J Clin Oncol, 41: 485-96, 2023.
  • Wang Q-L, Ma C, Yuan C, Shi Q, Wolpin BM, Zhang Y, Fuchs CS, Meyer J, Zemla T, Cheng E, Kumthekar P, Guthrie KA, Couture F, Kuebler P, Kumar P, Tan B, Krishnamurthi S, Goldberg RM, Venook A, Blanke C, Shields AF, O'Reilly EM, Meyerhardt JA, Ng K. Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance). Clinical Cancer Research 29: 2621-2630. 2023.
  • Wang Z, Li W, Ding H, Tu D. A composite semiparametric homogeneity test for the distributions of multigroup interval-bounded longitudinal data (ONLINE). Journal of Biopharmaceutical Statistics 2023.
  • Wang Z, Liu H, Ding H, Tu D, Wu Y. Semiparametric regression analysis of doubly censored longitudinal data with informative observation times (ONLINE). SCIENTIA SINICA Mathematica. 2023.
  • Wang Z, Li T, Xiao L, Tu D. A threshold longitudinal Tobit quantile regression model for identification of treatment-sensitive subgroups based on interval-bounded longitudinal measurements and a continuous covariate. Statistics in Medicine 42: 4618-4631. 2023.
  • Weiss AR, Chen Y-L, Scharschmidt TJ, Xue W, Gao Z, Black JO, Choy E, Davis JL, Fanburg-Smith JC, Kao SC, Kayton ML, Kessel S, Lim R, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Shulkin BL, Terezakis S, Venkatramani R, Zambrano E, Wang D, Hawkins DS, Spunt SL. Outcomes After Preoperative Chemoradiation With or Without Pazopanib in Non-Rhabdomyosarcoma Soft Tissue Sarcoma: A Report From Children's Oncology Group and NRG Oncology. Journal of Clinical Oncology 41: 4842-4848. 2023.
  • Yap C, Rekowski J, Ursino M, Solovyeva O, Patel D, Dimairo M, Weir CJ, Chan A-W, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Calvert M, Rantell KR, Lee S, Kightley A, Hopewell S, Ashby D, Garrett-Mayer E, Isaacs J, Golub R, Kholmanskikh O, Richards DP, Boix O, Matcham J, Seymour L, Ivy SP, Marshall LV, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, Bono Jd. Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ 383: e076386. 2023.
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  • Zhang J, Kong W, Hu P, Jonker D, Moore M, Ringash J, Shapiro J, Zalcberg J, Simes J, Tu D, O'Callaghan CJ, Liu G, Xu W. Clustering on longitudinal quality-of-life measurements using growth mixture models for clinical prognosis: Implementation on CCTG/AGITG CO.20 trial. Cancer Med 12: 6117-28, 2023.
  • Zhao Z, Song Y, Jiang W, Tu D. Consistent covariances estimation for stratum imbalances under minimization method for covariate-adaptive randomization (ONLINE). Scandinavian Journal of Statistics. 2023.
  • Cheng E, Ou FS, Ma C, Spiegelman D, Zhang S, Zhou X, Bainter TM, Saltz LB, Niedzwiecki D, Mayer RJ, Whittom R, Hantel A, Benson A, Atienza D, Messino M, Kindler H, Giovannucci EL, Van Blarigan EL, Brown JC, Ng K, Gross CP, Meyerhardt JA, Fuchs CS. Diet- and Lifestyle-Based Prediction Models to Estimate Cancer Recurrence and Death in Patients With Stage III Colon Cancer (CALGB 89803/Alliance). J Clin Oncol 40: 740-51, 2022.
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  • Everest L, Blommaert S, Tu D, Pater JL, Hay A, Cheung MC, Chan KKW. Validating Restricted Mean Survival Time Estimates From Reconstructed Kaplan-Meier Data Against Original Trial Individual Patient Data From Trials Conducted by the Canadian Cancer Trials Group. Value In Health 25: 1157-64, 2022.
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  • Gnant M, Dueck AC, Frantal S, Martin M, Burstein HJ, Greil R, Fox P, Wolff AC, Chan A, Winer EP, Pfeiler G, Miller KD, Colleoni M, Suga JM, Rubovsky G, Bliss JM, Mayer IA, Singer CF, Nowecki Z, Hahn O, Thomson J, Wolmark N, Amillano K, Rugo HS, Steger GG, Hernando Fernández de Aránguiz B, Haddad TC, Perelló¦ A, Bellet M, Fohler H, Metzger Filho O, Jallitsch-Halper A, Solomon K, Schurmans C, Theall KP, Lu DR, Tenner K, Fesl C, DeMichele A, Mayer EL. Adjuvant Palbociclib for Early Breast Cancer: The PALLAS Trial Results (ABCSG-42/AFT-05/BIG-14-03). J Clin Oncol 40: 282-93, 2022.
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  • Kulke MH, Ou FS, Niedzwiecki D, Huebner L, Kunz P, Kennecke HF, Wolin EM, Chan JA, O'Reilly EM, Meyerhardt JA, Venook A. Everolimus with or without bevacizumab in advanced pNET: CALGB 80701 (Alliance). Endocrine-Related Cancer 29: 335-44, 2022.
  • Leighl NB, Laurie SA, Goss GD, Hughes BGM, Stockler M, Tsao MS, Hwang DM, Joubert P, Kulkarni S, Blais N, Joy AA, Mates M, Rana P, Yadav SK, Underhill C, Lee C, Bradbury PA, Hiltz A, Dancey J, Ding K, Vera-Badillo F. CCTG BR34: A randomized phase II trial of durvalumab and tremelimumab +/- platinum-based chemotherapy in patients with metastatic non-small cell lung cancer. J Thoracic Oncol 17: 434-45, 2022.
  • Li Y, Zheng X, Tu D, Ingle JN, Goss PE, Parulekar WR, Qin G. Predicting the clinical outcomes and benefit from letrozole after 5-áyears of treatment with aromatase inhibitors for early breast cancer: analysis from CCTG MA.17R. Breast Cancer Res Treat 191: 523-33, 2022
  • Liu JF, Brady MF, Matulonis UA, Miller A, Kohn EC, Swisher EM, Cella D, Tew WP, Cloven NG, Muller CY, Bender DP, Moore RG, Michelin DP, Waggoner SE, Geller MA, Fujiwara K, D'Andre SD, Carney M, varez Secord A, Moxley KM, Bookman MA. Olaparib With or Without Cediranib Versus Platinum-Based Chemotherapy in Recurrent Platinum-Sensitive Ovarian Cancer (NRG-GY004): A Randomized, Open-Label, Phase III Trial. J Clin Oncol 40: 2138-47, 2022.
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  • Mayer EL, Fesl C, Hlauschek D, Garcia-Estevez L, Burstein HJ, Zdenkowski N, Wette V, Miller KD, Balic M, Mayer IA, Cameron D, Winer EP, Ponce Lorenzo JJ, Lake D, Pristauz-Telsnigg G, Haddad TC, Shepherd L, Iwata H, Goetz M, Cardoso F, Traina TA, Sabanathan D, Breitenstein U, Ackerl K, Metzger Filho O, Zehetner K, Solomon K, El-Abed S, Theall KP, Lu DR, Dueck A, Gnant M, DeMichele A. Treatment Exposure and Discontinuation in the PALbociclib CoLlaborative Adjuvant Study of Palbociclib With Adjuvant Endocrine Therapy for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer (PALLAS/AFT-05/ABCSG-42/BIG-14-03). J Clin Oncol 40: 449-58, 2022.
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  • Rattner JI, Kopciuk KA, Vogel HJ, Tang PA, Shapiro JD, Tu D, Jonker DJ, Siu LL, O'Callaghan CJ, Bathe OF. Early detection of treatment futility in patients with metastatic colorectal cancer (ONLINE). Oncotarget 13: 61-72, 2022.
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  • Vergote I, Gonzalez-Martin A, Lorusso D, Gourley C, Mirza MR, Kurtz JE, Okamoto A, Moore K, Kridelka F, McNeish I, Reuss A, Votan B, du Bois A, Mahner S, Ray-Coquard I, Kohn EC, Berek JS, Tan DSP, Colombo N, Zang R, Concin N, O'Donnell D, Rauh-Hain A, Herrington CS, Marth C, Poveda A, Fujiwara K, Stuart GCE, Oza AM, Bookman MA, Mahner S, Reuss A, du Bois A, Grimm C, Marth C, Berger R, Concin N, Chang TC, Ochiai K, Gebski V, Davis A, Beale P, Vergote I, Kridelka F, Denys H, Vandecaveye V, Candido dos Reis FJ, Del Pilar Estevez Diz M, Stuart G, Mackay H, Carey M, Cibula D, Dundr p, Dorigo O, Berek J, O'Donnell D, Saadeh A, Boere I, Lok C, Coronado P, Ottevanger N, Tan DS, Ng J, Gonzalez Martin A, Oaknin A, Poveda A, Perez Fidalgo A, Rauh-Hain A, Lu K, López-Zavala C, Gómez-García EM, Ray-Coquard I, Paoletti X, Kurtz JE, Joly F, Votan B, Bookman M, Moore K, Arend R, Fujiwara K, Fujiwara H, Hasegawa K, Bruchim I, Tsoref D, Oda K, Okamoto A, Enomoto T, Michel D, Kim HS, Lee JY, Mukhopadhyay A, Katsaros D, Colombo N, Pignata S, Lorusso D, Scambia G, Kohn E, Lee JM, McNeish I, Nicum S, Farrelly L, Sehouli J, Keller M, Braicu E, Bjorge L, Mirza MR, Auranen A, Welch S, Oza AM, Heinzelmann V, Gourley C, Roxburgh P, Herrington CS, Glasspool R, Zang R, Zhu J. Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup. The Lancet Oncology 23: e374-e384, 2022.
  • Wang Z, Xu H, Liu H, Song H, Tu D. A Joint Model for Longitudinal Outcomes with Potential Floor or Ceiling Effects and Survival Times, with Applications to Analysis of Quality of Life Data from a Cancer Clinical Trial. Stat 11: e412-e422, 2022.
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  • Eastham JA, Heller G, Halabi S, Monk JP, Beltran H, Gleave M, Evans CP, Clinton SK, Szmulewitz RZ, Coleman J, Hillman DW, Watt CR, George S, Sanda MG, Hahn OM, Taplin ME, Parsons JK, Mohler JL, Small EJ, Morris MJ. Cancer and Leukemia Group B 90203 (Alliance): Radical Prostatectomy With or Without Neoadjuvant Chemohormonal Therapy in Localized, High-Risk Prostate Cancer. J Clin Oncol 38: 3042-50, 2020.
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  • Ge X, Peng Y, Tu D. A threshold linear mixed model for identification of treatment-sensitive subsets in a clinical trial based on longitudinal outcomes and a continuous covariate. Stat Methods Med Res 29: 2919-31, 2020.
  • Goodwin R, Jonker D, Chen E, Kennecke H, Cabanero M, Tsao MS, Vickers M, Bohemier C, Lim H, Ritter H, Tu D, Seymour L. A phase Ib study of a PI3Kinase inhibitor BKM120 in combination with panitumumab in patients with KRAS wild-type advanced colorectal cancer. Invest New Drugs 38: 1007-84, 2020.
  • Gralow JR, Barlow WE, Paterson AHG, Miao JL, Lew DL, Stopeck AT, Hayes DF, Hershman DL, Schubert MM, Clemons M, Van Poznak CH, Dees EC, Ingle JN, Falkson CI, Elias AD, Messino MJ, Margolis JH, Dakhil SR, Chew HK, Dammann KZ, Abrams JS, Livingston RB, Hortobagyi GN. Phase III randomized trial of bisphosphonates as adjuvant therapy in breast cancer: S0307. JNCI: Journal of the National Cancer Institute 112: 698-707, 2020.
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  • Ho V, Pasquet R, Luo S, Chen G, Goss P, Tu D, Lazarus P, Richardson H. Variation in the UGT2B17 genotype, exemestane metabolism and menopause-related toxicities in the CCTG MAP.3 trial. Breast Cancer Res Treat 183: 705-16, 2020.
  • Ingle JN, Cairns J, Suman VJ, Shepherd LE, Fasching PA, Singh RJ, Zeruesenay D, Kalari KR, Ellis MJ, Goss PE, Chen BE, Volz B, Barman P, Carlson EE, Haddad T, Goetz MP, Goodnature B, Cuellar ME, Walters MA, Correia C, Kaufmann SH, Weinshilboum RM, Wang L. Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor . Clin Cancer Res 26: 2986-96, 2020.
  • Juergens RA, Hao D, Ellis PM, Tu D, Mates M, Kollmannsberger C, Bradbury PA, Tehfe M, Wheatley-Price P, Robinson A, Bebb G, Laskin J, Goffin J, Hilton J, Tomiak A, Hotte S, Goss GD, Brown-Walker P, Sun X, Tsao MS, Cabanero M, Gauthier I, Song X, Dennis PA, Seymour LK, Smoragiewicz M, Laurie SA. A phase IB study of durvalumab with or without tremelimumab and platinum-doublet chemotherapy in advanced solid tumours: Canadian Cancer Trials Group Study IND226. Lung Cancer 143: 1-11, 2020.
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  • Lapointe S, Mason W, MacNeil M, Harlos C, Tsang R, Sederias J, Luchman HA, Weiss S, Rossiter JP, Tu D, Seymour L, Smoragiewicz M. A phase I study of vistusertib (dual mTORC1/2 inhibitor) in patients with previously treated glioblastoma multiforme: a CCTG study . Invest New Drugs 38: 1137-44, 2020.
  • León-Castillo A, de Boer SM, Powell ME, Mileshkin LR, Mackay HJ, Leary A, Nijman HW, Singh N, Pollock PM, Bessette P, Fyles A, Haie-Meder C, Smit VTHB, Edmondson RJ, Putter H, Kitchener HC, Crosbie EJ, De Bruyn M, Nout RA, Horeweg N, Creutzberg CL, Bosse T. Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy. J Clin Oncol 38: 3388-97, 2020.
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  • Richardson H, Ho V, Pasquet R, Singh RJ, Goetz MP, Tu D, Goss PE, Ingle JN, on behalf of the MAP. Baseline estrogen levels in postmenopausal women participating in the MAP.3 breast cancer chemoprevention trial. Menopause 27: 693-700, 2020.
  • Rushton CK, Arthur SE, Alcaide M, Cheung M, Jiang A, Coyle KM, Cleary KLS, Thomas N, Hilton LK, Michaud N, Daigle S, Davidson J, Bushell K, Yu S, Rys RN, Jain M, Shepherd L, Marra MA, Kuruvilla J, Crump M, Mann K, Assouline S, Connors JM, Steidl C, Cragg MS, Scott DW, Johnson NA, Morin RD. Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma. Blood advances 4: 2886-98, 2020.
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  • Wang C, Tu D. A bootstrap semiparametric homogeneity test for the distributions of multigroup proportional data, with applications to analysis of quality of life outcomes in clinical trials. Statist Med 39: 1715-31, 2020.
  • Weiss AR, Chen YL, Scharschmidt TJ, Chi YY, Tian J, Black JO, Davis JL, Fanburg-Smith JC, Zambrano E, Anderson J, Arens R, Binitie O, Choy E, Davis JW, Hayes-Jordan A, Kao SC, Kayton ML, Kessel S, Lim R, Meyer WH, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Schlapkohl M, Shulkin BL, Smith EA, Sorger JI, Terezakis S, Hawkins DS, Spunt SL, Wang D. Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial. The Lancet Oncology 21: 1110-22, 2020.
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  • Cheung WY, Kornelsen EA, Mittmann N, Leighl NB, Cheung M, Chan KK, Bradbury PA, Ng RCH, Chen BE, Ding K, Pater JL, Tu D, Hay AE. The economic impact of the transition from branded to generic oncology drugs. Curr Oncol 2019/04/01: 89-93, 2019.
  • Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L. A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229). The Oncologist 24: 1439-45, 2019.
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  • Zorzi AP, Bernstein M, Samson Y, Wall DA, Desai S, Nicksy D, Wainman N, Eisenhauer E, Baruchel S. A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium. Pediatr Blood Cancer 60: 1868-74, 2013.
  • Alberts SR, Sargent DJ, Nair S, Mahoney MR, Mooney M, Thibodeau SN, Smyrk TC, Sinicrope FA, Chan E, Gill S, Kahlenberg MS, Shields AF, Quesenberry JT, Webb TA, Farr GH, Pockaj BA, Grothey A, Goldberg RM. Effect of Oxaliplatin, Fluorouracil, and Leucovorin With or Without Cetuximab on Survival Among Patients With Resected Stage III Colon Cancer. J Am Med Assoc 307: 1383-93, 2012.
  • Alexandre J, Brown C, Coeffic D, Raban N, Pfisterer J, Maenpaa J, Chalchal H, Fitzharris B, Volgger B, Vergote I, Pisano C, Ferrero A, Pujade-Lauraine E. CA-125 can be part of the tumour evaluation criteria in ovarian cancer trials: experience of the GCIG CALYPSO trial. Br J Cancer 106: 633-7, 2012.
  • Bellmunt J, von der Maase H, Mead GM, Skoneczna I, De Santis M, Daugaard G, Boehle A, Chevreau C, Paz-Ares L, Laufman LR, Winquist E, Raghavan D, Marreaud S, Collette S, Sylvester R, de Wit R. Randomized Phase III Study Comparing Paclitaxel/Cisplatin/ Gemcitabine and Gemcitabine/Cisplatin in Patients With Locally Advanced or Metastatic Urothelial Cancer Without Prior Systemic Therapy: EORTC Intergroup Study 30987. J Clin Oncol 30: 1107-13, 2012.
  • Booth CM, Eisenhauer EA. Progression-Free Survival: Meaningful or Simply Measurable? J Clin Oncol 30: 1030-3, 2012.
  • Brundage M, Gropp M, Mefti F, Mann K, Lund B, Gebski V, Wolfram G, Reed N, Pignata S, Ferrero A, Brown C, Eisenhauer E, Pujade-Lauraine E. Health-related quality of life in recurrent platinum-sensitive ovarian cancer--results from the CALYPSO trial. Ann Oncol 23: 2020-7, 2012.
  • Busaidy NL, Farooki A, Dowlati A, Perentesis JP, Dancey JE, Doyle LA, Brell JM, Siu LL. Management of Metabolic Effects Associated With Anticancer Agents Targeting the PI3K-Akt-mTOR Pathway. J Clin Oncol 30: 2919-28, 2012.
  • Carbone DP, Ding K, Roder H, Grigorieva J, Roder J, Tsao MS, Seymour L, Shepherd FA. Prognostic and Predictive Role of the VeriStrat Plasma Test in Patients with Advanced Non-Small-Cell Lung Cancer Treated with Erlotinib or Placebo in the NCIC Clinical Trials Group BR.21 Trial. J Thoracic Oncol 7: 1653-60, 2012.
  • Cheang MC, Voduc KD, Tu D, Jiang S, Leung S, Chia SK, Shepherd L, Levine MN, Pritchard KI, Davies SR, Stijleman IJ, Davis C, Ebbert M, Parker JS, Ellis MJ, Bernard PS, Perou CM, Nielsen TO. Responsiveness of intrinsic subtypes to adjuvant anthracycline substitution in the NCIC.CTG MA.5 randomized trial. Clin Cancer Res 18: 2402-12, 2012.
  • Cheung AM, Tile L, Cardew S, Pruthi S, Robbins J, Tomlinson G, Kapral MK, Khosla S, Majumdar S, Erlandson M, Scher J, Hu H, Demaras A, Lickley L, Bordeleau L, Elser C, Ingle J, Richardson H, Goss PE. Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial. The Lancet Oncology 13: 275-84, 2012.
  • Chia SK, Bramwell-Wesley V, Tu D, Shepherd L, Jiang S, Vickery T, Mardis E, Leung S, Ung K, Pritchard KI, Parker J, Bernard PS, Perou CM, Ellis MJ, Nielsen TO. A 50 Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen. Clin Cancer Res 18: 4465-72, 2012.
  • Crook JM, O'Callaghan CJ, Duncan G, Dearnaley DP, Higano CS, Horwitz EM, Frymire E, Malone S, Chin J, Nabid A, Warde P, Corbett T, Angyalfi S, Goldenberg SL, Gospodarowicz MK, Saad F, Logue JP, Hall E, Schellhammer PF, Ding K, Klotz L. Intermittent Androgen Suppression for Rising PSA Level after Radiotherapy. N Engl J Med 367: 895-903, 2012.
  • Cuffe S, Bourredjem A, Graziano S, Pignon JP, Domerg C, Ezzalfani M, Seymour L, Strevel E, Burkes R, Capelletti M, Jänne PA, Tsao MS, Shepherd FA. A Pooled Exploratory Analysis of the Effect of Tumor Size and KRAS Mutations on Survival Benefit From Adjuvant Platinum-Based Chemotherapy in Node-Negative Non-Small Cell Lung Cancer. J Thoracic Oncol 7: 963-72, 2012.
  • Dancey J. Genomics, personalized medicine and cancer practice. Clinical Biochemistry 45: 379-81, 2012.
  • Dancey JE, Bedard PL, Onetto N, Hudson TJ. The Genetic Basis for Cancer Treatment Decisions. Cell 148: 409-20, 2012.
  • Davies MA, Fox PS, Papadopoulos NE, Bedikian AY, Hwu WJ, Lazar AJ, Prieto VG, Culotta KS, Madden TL, Xu Q, Huang S, Deng W, Ng CS, Gupta S, Liu W, Dancey JE, Wright JJ, Bassett RL, Hwu P, Kim KB. Phase I Study of the Combination of Sorafenib and Temsirolimus in Patients with Metastatic Melanoma. Clin Cancer Res 18: 1120, 2012.
  • de Almeida JR, Vescan AD, Gullane PJ, Gentili F, Lee JM, Lohfeld L, Ringash J, Thoma A, Witterick IJ. Development of a disease-specific quality-of-life questionnaire for anterior and central skull base pathology-The skull base inventory. The Laryngoscope 122: 1933-42, 2012.
  • de Souza JA, Davis DW, Zhang Y, Khattri A, Seiwert TY, Aktolga S, Wong SJ, Kozloff MF, Nattam S, Lingen MW, Kunnavakkam R, Stenson KM, Blair EA, Bozeman J, Dancey JE, Vokes EE, Cohen EEW. A Phase II Study of Lapatinib in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res 18: 2336-43, 2012.
  • Dong B, Matthews DE. Empirical Likelihood for Cumulative Hazard Ratio Estimation with Covariate Adjustment. Biometrics 68: 408-18, 2012.
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials. The Lancet 379: 432-44, 2012.
  • Gospodarowicz MK, Mason M, Parulekar W, Swanson G, Kirkbride P, Brundage M, Sydes M, Hetherington J, Chen B, Warde P. Final Analysis of Intergroup Randomized Phase III Study of Androgen Deprivation Therapy (ADT) ± Radiation Therapy (RT) in Locally Advanced Prostate Cancer (NCIC-CTG, SWOG, MRC-UK, INT: T94-0110; NCT00002633). International Journal of Radiation Oncology Biology Physics 84: S4, 2012.
  • Hay AE, Meyer RM. Hepatitis B, Rituximab, Screening, and Prophylaxis: Effectiveness and Cost Effectiveness. J Clin Oncol 30: 3155-7, 2012.
  • Hertel PB, Tu D, Ejlertsen B, Jensen M-B, Balslev E, Jiang S, O'Malley FP, Pritchard KI, Shepherd LE, Bartels A, Brünner N, Nielsen TO. TIMP-1 in combination with HER2 and TOP2 for prediction of benefit from adjuvant anthracyclines in high-risk breast cancer patients. Breast Cancer Res Treat 132: 225-34, 2012.
  • Jiang S, Tu D. Inference on the probability as a measurement of treatment effect under a density ratio model and random censoring. Computational Statistics and Data Analysis 56: 1069-78, 2012.
  • Jin H, Zhao N, Tu D. Nonparametric confidence intervals for the ratio of marginal hazard rates of paired survival times. Biom J 54: 197-213, 2012.
  • Jin H, Tu D, Zhao N, Shepherd LE, Goss PE. Longer-Term Outcomes of Letrozole Versus Placebo After 5 Years of Tamoxifen in the NCIC CTG MA.17 Trial: Analyses Adjusting for Treatment Crossover. J Clin Oncol 30: 718-21, 2012.
  • Kay A, Higgins J, Day AG, Meyer RM, Booth CM. Randomized controlled trials in the era of molecular oncology: methodology, biomarkers, and end points. Ann Oncol 23: 1646-51, 2012.
  • Kollmannsberger C, Hirte H, Siu LL, Mazurka J, Chi K, Elit L, Walsh W, Sederias J, Doyle A, Eisenhauer EA, Oza AM. Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179). Ann Oncol 23: 238-44, 2012.
  • Lee EQ, Kuhn J, Lamborn KR, Abrey L, DeAngelis LM, Lieberman F, Robins HI, Chang SM, Yung WKA, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados MD, Cloughesy TF, Gilbert MR, Wen PY. Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02. Neuro-Oncology 14: 1511-8, 2012.
  • Li X, Wu YH, Tu DS. Jackknifed random weighting for Cox proportional hazards model. Sci China Math 55: 775-86, 2012.
  • Lindemann K, Christensen RD, Vergote I, Stuart G, Izquierdo MA, Kaern J, Havsteen H, Eisenhauer E, Ridderheim M, Lopez AB, Hirte H, avall-Lundquvist E, Vrdoljak E, Green J, Kristensen GB. First-line treatment of advanced ovarian cancer with paclitaxel/carboplatin with or without epirubicin (TEC versus TC) - a gynecologic cancer intergroup study of the NSGO, EORTC GCG and NCIC CTG. Ann Oncol 23: 2613-9, 2012.
  • Liu G, Cheng D, Ding K, Le Maitre A, Liu N, Patel D, Chen Z, Seymour L, Shepherd FA, Tsao MS. Pharmacogenetic Analysis of BR.21, a Placebo-Controlled Randomized Phase III Clinical Trial of Erlotinib in Advanced Non-small Cell Lung Cancer. J Thoracic Oncol 7: 316-22, 2012.
  • Liu X, Peng Y, Tu D, Liang H. Variable selection in semiparametric cure models based on penalized likelihood, with application to breast cancer clinical trials. Stat Med 31: 2882-91, 2012.
  • Macdonald DA, Assouline SE, Brandwein J, Kamel-Reid S, Eisenhauer EA, Couban S, Caplan S, Foo A, Walsh W, Leber B. A Phase I/II Study of Sorafenib (BAY 43-9006) In Combination with Low Dose Cytarabine (LDAC) In Elderly Patients with AML or High-Risk MDS from the NCIC Clinical Trials Group: Trial IND.186 (ONLINE). Leuk Lymphoma 2012.
  • Mason W, MacNeil M, Kavan P, Easaw J, MacDonald D, Thiessen B, Urva S, Lwin Z, McIntosh L, Eisenhauer E. A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study. Invest New Drugs 30: 2344-51, 2012
  • Matzke EAM, O'Donoghue S, Barnes RO, Daudt H, Cheah S, Suggitt A, Bartlett J, Damaraju S, Johnston R, Murphy L, Shepherd L, Mes-Masson AM, Schacter B, Watson PH. Certification for Biobanks: The Program Developed by the Canadian Tumour Repository Network (CTRNet). Biopreservation and Biobanking 10: 426-32, 2012.
  • Mehta RS, Barlow WE, Albain KS, Vandenberg TA, Dakhil SR, Tirumali NR, Lew DL, Hayes DF, Gralow JR, Livingston RB, Hortobagyi GN. Combination Anastrozole and Fulvestrant in Metastatic Breast Cancer. N Engl J Med 367: 435-44, 2012.
  • Mehta RS, Barlow WE, Hortobagyi GN. Anastrozole and Fulvestrant in Metastatic Breast Cancer (Author Response). N Engl J Med 367: 1662-4, 2012.
  • Meyer RM, Hoppe RT. Point/counterpoint: early stage Hodgkin lymphoma: the role of radiation therapy. Blood 120: 4488-95, 2012.
  • Meyer RM. Evolution of Clinical Trials Registries (Editorial). J Clin Oncol 30: 131-3, 2012.
  • Meyer RM, Gospodarowicz MK, Connors JM, Pearcey RG, Wells WA, Winter JN, Horning SJ, Dar AR, Shustik C, Stewart DA, Crump M, Djurfeldt MS, Chen BE, Shepherd LE. ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma. N Engl J Med 366: 399-408, 2012.
  • Monzon JG, Dancey J. Targeted agents for the treatment of metastatic melanoma. OncoTargets and Therapy 2012: 31-46, 2012.
  • Monzon JG, Hammad N, Stevens SD, Dancey J. Retinopathy Associated with Adjuvant High-Dose Interferon-a2b in a Patient with Resected Melanoma: A Case Report and Review of the Literature. The Oncologist 17: 384-7, 2012.
  • Navaratnam S, Skliris G, Qing G, Banerji S, Badiani K, Tu D, Bradbury P, Leighl N, Shepherd F, Nowatzki J, Demers A, Murphy L. Differential Role of Estrogen Receptor Beta in Early Versus Metastatic Non-small Cell Lung Cancer. Hormones and Cancer 3: 93-100, 2012.
  • Peng Y, Xu J. An extended cure model and model selection. Lifetime Data Anal 18: 215-33, 2012.
  • Petrella TM, Tozer R, Belanger K, Savage KJ, Wong R, Smylie M, Kamel-Reid S, Tron V, Chen BE, Hunder NN, Hagerman L, Walsh W, Eisenhauer EA. Interleukin-21 Has Activity in Patients With Metastatic Melanoma: A Phase II Study. J Clin Oncol 30: 3396-401, 2012.
  • Pollak MN, Shepherd L, Pritchard KI. Reply to P. Ameri et al: Alternative Approach to Insulin-Like Growth Factor-1 Inhibition for Treatment of Breast Cancer. J Clin Oncol 30: 1396-7, 2012.
  • Pritchard K, Munro A, O'Malley FP, Tu D, Li X, Levine M, Shepherd L, Chia S, Bartlett J. Chromosome 17 centromere (CEP17) duplication as a predictor of anthracycline response: evidence from the NCIC Clinical Trials Group (NCIC CTG) MA.5 Trial. Breast Cancer Res Treat 131: 541-51, 2012.
  • Reiman T, Lai R, Veillard AS, Paris E, Soria JC, Rosell R, Taron M, Graziano S, Kratzke R, Seymour L, Shepherd FA, Pignon JP, Sève P, for the LACE-Bio Group. Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of four randomized trials. Ann Oncol 23: 86-93, 2012.
  • Renouf D, Moore M, Hedley D, Gill S, Jonker D, Chen E, Walde D, Goel R, Southwood B, Gauthier I, Walsh W, McIntosh L, Seymour L. A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer. Invest New Drugs 30: 779-86, 2012.
  • Song H, Peng Y, Tu D. A new approach for joint modelling of longitudinal measurements and survival times with a cure fraction. Can J Statistics 40: 207-24, 2012.
  • Tan KL, Scott DW, Hong F, Kahl BS, Fisher RI, Bartlett NL, Advani RH, Buckstein R, Rimsza LM, Connors JM, Steidl C, Gordon LI, Horning SJ, Gascoyne RD. Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial. Blood 120: 3280-7, 2012.
  • Tran B, Dancey JE, Kamel-Reid S, McPherson JD, Bedard PL, Brown AMK, Zhang T, Shaw P, Onetto N, Stein L, Hudson TJ, Neel BG, Siu LL. Cancer Genomics: Technology, Discovery, and Translation. J Clin Oncol 30: 647-60, 2012.
  • Vickers MM, Powell ED, Asmis TR, Jonker DJ, Hilton JF, O'Callaghan CJ, Tu D, Parulekar W, Moore MJ. Comorbidity, age and overall survival in patients with advanced pancreatic cancer - Results from NCIC CTG PA.3: A phase III trial of gemcitabine plus erlotinib or placebo. Eur J Can 48: 1434-42, 2012.
  • Wasan K, Goss P, Pritchard PH, Shepherd L, Tu D, Ingle JN. Lipid concentrations in postmenopausal women on letrozole after 5 years of tamoxifen: an NCIC CTG MA.17 sub-study. Breast Cancer Res Treat 136: 769-76, 2012.
  • Asmis TR, Powell E, Karapetis CS, Jonker DJ, Tu D, Jeffery M, Pavlakis N, Gibbs P, Zhu L, Dueck D-A, Whittom R, Langer C, O'Callaghan CJ. Comorbidity, age and overall survival in cetuximab-treated patients with advanced colorectal cancer (ACRC) - results from NCIC CTG CO.17: a phase III trial of cetuximab versus best supportive care. Ann Oncol 22: 118-26, 2011.
  • Bertagnolli MM, Redston M, Compton CC, Niedzwiecki D, Mayer RJ, Goldberg RM, Colacchio TA, Saltz LB, Warren RS. Microsatellite Instability and Loss of Heterozygosity at Chromosomal Location 18q: Prospective Evaluation of Biomarkers for Stages II and III Colon Cancer-A Study of CALGB 9581 and 89803. J Clin Oncol 29: 3153-62, 2011.
  • Biagi JJ, Oza AM, Chalchal HI, Grimshaw R, Ellard SL, Lee U, Hirte H, Sederias J, Ivy SP, Eisenhauer EA. A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group study. Ann Oncol 22: 335-40, 2011.
  • Booth CM, Ohorodnyk P, Zhu L, Tu D, Meyer RM. Randomised controlled trials in oncology closed early for benefit: Trends in methodology, results, and interpretation. Eur J Can 47: 854-63, 2011.
  • Bradbury P, Hilton J, Seymour L. Early-phase oncology clinical trial design in the era of molecularly targeted therapy: pitfalls and progress. Clin Invest 1: 33-44, 2011.
  • Brundage M, Bass B, Davidson J, Queenan J, Bezjak A, Ringash J, Wilkinson A, Feldman-Stewart D. Patterns of reporting health-related quality of life outcomes in randomized clinical trials: implications for clinicians and quality of life researchers. Qual Life Res 20: 653-64, 2011.
  • Brundage M, Bass B, Jolie R, Foley K. A knowledge translation challenge: clinical use of quality of life data from cancer clinical trials. Qual Life Res 20: 979-85, 2011.
  • Buckstein R, Kuruvilla J, Chua N, Lee C, Macdonald DA, Al-tourah AJ, Foo AH, Walsh W, Percy ivy S, Crump M, Eisenhauer EA. Sunitinib in Relapsed or Refractory Diffuse Large B Cell Lymphoma: A Clinical and Pharmacodynamic Phase II Multi-Center Study of the NCIC Clinical Trials Group. Leuk Lymphoma 52: 833-41, 2011.
  • Cigler T, Richardson H, Yaffe MJ, Fabian CJ, Johnston D, Ingle JN, Nassif E, Brunner RL, Wood ME, Pater JL, Hu H, Qi S, Tu D, Goss PE. A randomized, placebo-controlled trial (NCIC CTG MAP.2) examining the effects of exemestane on mammographic breast density, bone density, markers of bone metabolism and serum lipid levels in postmenopausal women. Breast Cancer Res Treat 126: 453-61, 2011.
  • Dancey JE, Monzon J. Ridaforolimus: a promising drug in the treatment of soft-tissue sarcoma and other malignancies. Future Oncology 7: 827-39, 2011
  • Di Leo A, Desmedt C, Bartlett JMS, Piette F, Ejlertsen B, Pritchard KI, Larsimont D, Poole C, Isola J, Earl H, Mouridsen H, O'Malley FP, Cardoso F, Tanner M, Munro A, Twelves CJ, Sotiriou C, Shepherd L, Cameron D, Piccart MJ, Buyse M, for the HER2/TOP2A Meta-analysis Study Group. HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual patient data. The Lancet Oncology 12: 1134-42, 2011.
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet 378: 771-84, 2011.
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials. Lancet 378: 1707-16, 2011.
  • Eisenhauer EA. Optimal assessment of response in ovarian cancer. Ann Oncol 22: viii49-viii51, 2011.
  • Fleshner NE, Kapusta L, Donnelly B, Tanguay S, Chin J, Hersey K, Farley A, Jansz K, Siemens DR, Trpkov K, Lacombe L, Gleave M, Tu D, Parulekar WR. Progression From High-Grade Prostatic Intraepithelial Neoplasia to Cancer: A Randomized Trial of Combination Vitamin-E, Soy, and Selenium. J Clin Oncol 29: 2386-90, 2011.
  • Friedlander M, Trimble E, Tinker A, Alberts D, Avall-Lundqvist E, Brady M, Harter P, Pignata S, Pujade-Lauraine E, Sehouli J, Vergote I, Beale P, Bekkers R, Calvert P, Copeland L, Glasspool R, Gonzalez-Martin A, Katsaros D, Kim JW, Miller B, Provencher D, Rubinstein L, Atri M, Zeimet A, Bacon M, Kitchener H, Stuart GCE, on behalf of the Gynecologic Cancer Intergroup. Clinical Trials in Recurrent Ovarian Cancer. Int J Gynecol Cancer 21: 771-5, 2011.
  • Gan HK, Bernstein LJ, Brown J, Ringash J, Vakilha M, Wang L, Goldstein D, Kim J, Hope A, O'Sullivan B, Waldron J, Razak ARA, Chen EX, Siu LL. Cognitive Functioning After Radiotherapy or Chemoradiotherapy for Head-and-Neck Cancer. International Journal of Radiation Oncology*Biology*Physics 81: 126-34, 2011
  • Goffin J, Pond G, Tu D. A comparison of a new multinomial stopping rule with stopping rules of fleming and gehan in single arm phase II cancer clinical trials. BMC Medical Research Methodology 11: 95, 2011.
  • Goodwin PJ, Stambolic V, Lemieux J, Chen BE, Parulekar WR, Gelmon KA, Hershman DL, Hobday TJ, Ligibel JA, Mayer IA, Pritchard KI, Whelan TJ, Rastogi P, Shepherd LE. Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents. Breast Cancer Res Treat 126: 215-20, 2011.
  • Gore EM, Bae K, Wong SJ, Sun A, Bonner JA, Schild SE, Gaspar LE, Bogart JA, Werner-Wasik M, Choy H. Phase III comparison of prophylactic cranial irradiation versus observation in patients with locally advanced non-small-cell lung cancer: Primary analysis of Radiation Therapy Oncology Group Study RTOG 0214. J Clin Oncol 29: 272-8, 2011.
  • Goss PE, Ingle JN, Alés-Martinez JE, Cheung AM, Chlebowski RT, Wactawski-Wende J, McTiernan A, Robbins J, Johnson KC, Martin LW, Winquist E, Sarto GE, Garber JE, Fabian CJ, Pujol P, Maunsell E, Farmer P, Gelmon KA, Tu D, Richardson H. Exemestane for Breast-Cancer Prevention in Postmenopausal Women. N Engl J Med 364: 2381-91, 2011.
  • Kouroukis CT, Fernandez LAV, Crump M, Chua NS, Buckstein R, Turner R, Assouline S, Klasa RJ, Walsh W, Powers J, Eisenhauer E. A phase II study of bortezomib and gemcitabine in relapsed mantle cell lymphoma from the National Cancer Institute of Canada Clinical Trials Group (IND 172). Leuk Lymphoma 52: 394-9, 2011.
  • Kulke MH, Siu LL, Tepper JE, Fisher G, Jaffe D, Haller DG, Ellis LM, Benedetti JK, Bergsland EK, Hobday TJ, Van Cutsem E, Pingpank J, Oberg K, Cohen SJ, Posner MC, Yao JC. Future Directions in the Treatment of Neuroendocrine Tumors: Consensus Report of the National Cancer Institute Neuroendocrine Tumor Clinical Trials Planning Meeting. J Clin Oncol 29: 934-43, 2011.
  • Kurtz JE, Kaminsky MC, Floquet A, Veillard AS, Kimmig R, Dorum A, Elit L, Buck M, Petru E, Reed N, Scambia G, Varsellona N, Brown C, Pujade-Lauraine E, on behalf of Gynecologic Cancer Intergroup. Ovarian cancer in elderly patients: carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in late relapse: a Gynecologic Cancer Intergroup (GCIG) CALYPSO sub-study. Ann Oncol 22: 2417-23, 2011.
  • Laurie SA, Gupta A, Chu Q, Lee CW, Morzycki W, Feld R, Foo AH, Seely J, Goffin JR, Laberge F, Murray N, Rao S, Nicholas G, Laskin J, Reiman T, Sauciuc D, Seymour L. Brief Report: A Phase II Study of Sunitinib in Malignant Pleural Mesothelioma. The NCIC Clinical Trials Group. J Thoracic Oncol 6: 1950-4, 2011.
  • Ledermann JA, Marth C, Carey MS, Birrer M, Bowtell DDL, Kaye S, McNeish I, Oza A, Scambia G, Rustin G, Stehman FB, Gershenson D, Thomas G, Berns E, Casado A, Ottevanger N, Hilpert F, Kim BG, Okamoto A, Bacon M, Kitchener H, Stuart GCE, and on behalf of the Gynecologic Cancer InterGroup. Role of Molecular Agents and Targeted Therapy in Clinical Trials for Women With Ovarian Cancer. Int J Gynecol Cancer 21: 763-70, 2011.
  • Lee CK, Gurney H, Brown C, Sorio R, Donadello N, Tulunay G, Meier W, Bacon M, Maenpaa J, Petru E, Reed N, Gebski V, Pujade-Lauraine E, Lord S, Simes RJ, Friedlander M. Carboplatin-paclitaxel-induced leukopenia and neuropathy predict progression-free survival in recurrent ovarian cancer. Br J Cancer 105: 360-5, 2011.
  • Lemieux J, Goodwin PJ, Bordeleau LJ, Lauzier S, Théberge V. Quality-of-Life Measurement in Randomized Clinical Trials in Breast Cancer: An Updated Systematic Review (20012009). J Natl Cancer Inst 103: 178-231, 2011.
  • Li X, Chen J, Wu Y, Tu D. Constructing Nonparametric Likelihood Confidence Regions With High Order Precisions. Statistica Sinica 21: 1767-83, 2011.
  • Lipton A, Chapman JA, Demers L, Shepherd LE, Han L, Wilson CF, Pritchard KI, Leitzel KE, Ali SM, Pollak M. Elevated Bone Turnover Predicts for Bone Metastasis in Postmenopausal Breast Cancer: Results of NCIC CTG MA.14. J Clin Oncol 29: 3605-10, 2011.
  • Lyerly HK, Abernethy AP, Stockler MR, Koczwara B, Aziz Z, Nair R, Seymour L. Need for Global Partnership in Cancer Care: Perceptions of Cancer Care Researchers Attending the 2010 Australia and Asia Pacific Clinical Oncology Research Development Workshop. Journal of Oncology Practice 7: 324-9, 2011.
  • Mackay HJ, Provencher D, Heywood M, Tu D, Eisenhauer EA, Oza AM, Meyer R. Phase II/III study of intraperitoneal chemotherapy after neoadjuvant chemotherapy for ovarian cancer: NCIC CTG OV.21. Current Oncology 18: 84-90, 2011.
  • Maringwa J, Quinten C, King M, Ringash J, Osoba D, Coens C, Martinelli F, Reeve BB, Gotay C, Greimel E, Flechtner H, Cleeland CS, Schmucker-Von Koch J, Weis J, van den Bent MJ, Stupp R, Taphoorn MJ, Bottomley A. Minimal clinically meaningful differences for the EORTC QLQ-C30 and EORTC QLQ-BN20 scales in brain cancer patients. Ann Oncol 22: 2107-12, 2011.
  • Martinelli F, Quinten C, Maringwa JT, Coens C, Vercauteren J, Cleeland CS, Flechtner H, Gotay C, Greimel E, King M, Mendoza T, Osoba D, Reeve BB, Ringash J, Koch JS-V, Shi Q, Taphoorn MJ, Weis J, Bottomley A. Examining the relationships among health-related quality-of-life indicators in cancer patients participating in clinical trials: a pooled study of baseline EORTC QLQ-C30 data. Expert Review of Pharmacoeconomics & Outcomes Research 11: 587-99, 2011.
  • Meyer RM, Stanton HA, Parulekar WR, Saad F. Cooperative Group Cancer Clinical Trials: An NCIC Clinical Trials Group Perspective. Canadian Urological Association Journal 5: 379-81, 2011.
  • Meyer RM. Contrasting Explanatory and Pragmatic Randomized Controlled Trials in Oncology. Am Soc Clin Oncol Educational Book 72-5, 2011.
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  • Au H-J, Karapetis CS, O'Callaghan CJ, Tu D, Moore MJ, Zalcberg JR, Kennecke H, Shapiro JD, Koski S, Pavlakis N, Charpentier D, Wyld D, Jefford M, Knight GJ, Magoski NM, Brundage MD, Jonker DJ. Health-related quality of life in patients with advanced colorectal cancer treated with cetuximab: Overall and KRAS-specific results of the NCIC CTG and AGITG CO.17 trial. J Clin Oncol 27: 1822-8, 2009.
  • Axelrod DE, Miller N, Chapman J-AW. Avoiding Pitfalls in the Statistical Analysis of Heterogeneous Tumors. Biomedical Informatics Insights 2: 11-8, 2009.
  • Bjarnason GA, MacKenzie RG, Nabid A, Hodson ID, El-Sayed SM, Grimard L, Brundage M, Wright J, Hay J, Ganguly P, Leong C, Wilson J, Jordan RCK, Walker M, Tu D, Parulekar W. Comparison of toxicity associated with early morning versus late afternoon radiotherapy in patients with head-and-neck cancer: A prospective randomized trial of the NCIC Clinical Trials Group (HN3). Int J Rad Oncol Biol Phys 73: 166-72, 2009.
  • Blake P, Swart AM, Orton J, Whelan T, Lukka H, Eisenhauer E, Bacon M, Tu D, Parmar MKB, Amos C, Murphy C, Qian W. Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis (The ASTEC/EN.5 writing committee on behalf the ASTEC/EN.5 Study Group). Lancet 373: 137-46, 2009.
  • Booth CM, Ohorodnyk P, Eisenhauer EA. Call for clarity in the reporting of benefit associated with anticancer therapies (Correspondence). J Clin Oncol 27: e213-e214, 2009.
  • Booth CM, Le Maître A, Ding K, Farn K, Fralick M, Phillips C, Cescon DW, Meyer RM. Presentation of nonfinal results of randomized controlled trials at major oncology meetings. J Clin Oncol 27: 3938-44, 2009.
  • Bradbury P, Seymour L. Tumor shrinkage and objective response rates: Gold standard for oncology efficacy screening trials, or an outdated end point? The Cancer Journal 15: 354-60, 2009.
  • Bradbury P, Meyer R, Pater J, Tu D, Seymour L, Shepherd L, Eisenhauer E. Stopping a trial early in oncology: for patients or for industry? (letter to the editor). Ann Oncol 20: 395-6, 2009.
  • Chen C, Kouroukis CT, White D, Voralia M, Stadtmauer E, Stewart AK, Wright JJ, Powers J, Walsh W, Eisenhauer E. Bortezomib in relapsed or refractory Waldenstrom's macroglobulinemia. Clinical Lymphoma & Myeloma 9: 74-6, 2009.
  • Chen E, Jones D, Gauthier I, MacLean M, Wells J, Powers J, Seymour L. Phase I study of cediranib in combination with oxaliplatin and infusional 5-fluorouracil in patients with advanced colorectal cancer. Clin Cancer Res 15: 1481-6, 2009.
  • Cheng M-Y, Qiu P, Tan X, Tu D. Confidence intervals for the first crossing point of two hazard functions. Lifetime Data Anal 15: 441-54, 2009.
  • Cheung MC, Imrie KR, Friedlich J, Buckstein R, Lathia N, Mittmann N. The impact of follicular (FL) and other indolent non-Hodgkin's lymphomas (NHL) on work productivity-a preliminary analysis. Psycho-Oncology 18: 554-9, 2009.
  • Chia S, Dent S, Ellard S, Ellis PM, Vandenberg T, Gelmon K, Powers J, Walsh W, Seymour L, Eisenhauer EA. Phase II trial of OGX-011 in combination with docetaxel in metastatic breast cancer. Clin Cancer Res 15: 708-13, 2009.
  • Crabb SJ, Patsios D, Sauerbrei E, Ellis PM, Arnold A, Goss G, Leighl NB, Shepherd FA, Powers J, Seymour L, Laurie SA. Tumor cavitation: Impact on objective response evaluation in trials of angiogenesis inhibitors in non-small-cell lung cancer. J Clin Oncol 27: 404-10, 2009.
  • DeMatteo RP, Ballman KV, Antonescu CR, Maki RG, Pisters PW, Demetri GD, Blackstein ME, Blanke CD, von Mehren M, Brennan MF, Patel S, McCarter MD, Polikoff JA, Tan BR, Owzar K, on behalf of the American College of Surgeons Oncology Group (ACOSOG) Intergroup Adjuvant GIST Study Team. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. The Lancet 373: 1097-104, 2009.
  • Dhani N, Tu D, Sargent J, Seymour L, Moore MJ. Alternate endpoints for screening phase II studies. Clin Cancer Res 15: 1873-82, 2009.
  • Douillard J-Y, Tribodet H, Aubert D, Shepherd FA, Rosell R, Ding K, Veillard A-S, Seymour L, LeChevalier T, Spiro S, Stephens R, Pignon JP, on behalf of the LACE Collaborative Group. Adjuvant cisplatin and vinorelbine for completely resected non-small cell lung cancer. Subgroup analysis of the Lung Adjuvant Cisplatin Evaluation. J Thoracic Oncol 5: 220-8, 2009.
  • Dowsett M, Procter M, McCaskill-Stevens W, de Azambuja E, Dafni U, Rueschoff J, Jordan B, Dolci S, Abramovitz M, Stoss O, Viale G, Gelber RD, Piccart-Gebhart M, Leyland-Jones B. Disease-free survival according to degree of HER2 amplification for patients treated with adjuvant chemotherapy with or without 1 year of trastuzumab: The HERA Trial. J Clin Oncol 27: 2962-9, 2009.
  • Eisenhauer E, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, Rubinstein L, Shankar L, Dodd L, Kaplan R, Lacombe D, Verweij J. New response evaluation criteria in solid tumors: Revised RECIST guideline version 1.1. Eur J Can 45: 228-47, 2009.
  • Ellard SL, Clemons M, Gelmon KA, Norris B, Kennecke H, Chia S, Pritchard K, Eisen A, Vandenberg T, Taylor M, Sauerbrei E, Mishaeli M, Huntsman D, Walsh W, Olivo M, McIntosh L, Seymour L. Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163. J Clin Oncol 27: 4536-41, 2009.
  • Goss G, Shepherd FA, Laurie S, Gauthier I, Leighl N, Chen E, Feld R, Powers J, Seymour L. A phase I and pharmacokinetic study of daily oral cediranib, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer: A study of the National Cancer Institute of Canada Clinical Trials Group. Eur J Can 45: 782-8, 2009.
  • Gregory J, Haesook K, Alonzo T, Gerbring R, Woods W, Weinstein H, Shepherd L, Schiffer C, Appelbaum F, Willman C, Wiernik P, Rowe J, Tallman M, Feusner J. Treatment of children with acute promyelocytic leukemia: results of the first North American Intergroup trial INT0129. Pediatric Blood & Cancer 53: 1005-10, 2009.
  • Hicks LK, Cheung MC, Ding K, Hasan B, Seymour L, Le Maître A, Leighl NB, Shepherd FA. Venous thromboembolism and nonsmall cell lung cancer: a pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials. Cancer 115: 5516-25, 2009.
  • Hussain M, Goldman B, Tangen C, Higano CS, Petrylak DP, Wilding G, Akdas AM, Small EJ, Donnelly BJ, Sundram SK, Burch PA, DiPaola RS, Crawford ED. Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: Data from Southwest Oncology Group trials 9346 (Intergroup Study 0162) and 9916. J Clin Oncol 27: 2450-6, 2009.
  • Jang RW, Le Maître A, Ding K, Winton T, Bezjak A, Seymour L, Shepherd FA, Leighl NB. Quality-adjusted time without symptoms or toxicity analysis of adjuvant chemotherapy in non-small-cell lung cancer: An analysis of the National Cancer Institute of Canada Clinical Trials Group JBR.10 trial. J Clin Oncol 27: 4268-73, 2009.
  • Le Maître A, Ding K, Shepherd FA, Leighl N, Arnold A, Seymour L. Anticoagulation and bleeding. A pooled analysis of lung cancer trials of the NCIC Clinical Trials Group. J Thoracic Oncol 4: 586-94, 2009.
  • Mittmann N, Au H-J, Tu D, O'Callaghan CJ, Isogai PK, Karapetis CS, Zalcberg JR, Evans WK, Moore MJ, Siddiqui J, Findlay B, Colwell B, Simes J, Gibbs P, Links M, Tebbutt NC, Jonker DJ, Working Group on Economic Analysis of the National Cancer Institute of Canada Clinical Trials Group, Australasian Gastrointestinal Interest Group. Prospective cost-effectiveness analysis of cetuximab in metastatic colorectal cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 trial. J Natl Cancer Inst 101: 1182-92, 2009.
  • Mittmann N, Evans WK, Rocchi A, Longo CJ, Au HJ, Husereau D, Leighl N, Isogai P, Krahn M, Peacock S, Marshall D, Coyle D, Malfair Taylor SC, Jacobs P, Oh PI. Addendum to CADTH's Guidelines for the Economic Evaluation of Health Technologies: Specific Guidance for Oncology Products. Canadian Agency for Drugs and Technologies in Health 2009.
  • O'Malley FP, Chia S, Tu D, Shepherd LE, Levine MN, Bramwell VH, Andrulis IL, Pritchard KI. Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy. J Natl Cancer Inst 101: 644-50, 2009.
  • Muss HB, Berry DA, Cirrincione C, Theodoulou M, Mauer AM, Kornblith AB, Partridge AH, Dressler LG, Cohen HJ, Becker HP, Kartcheske PA, Wheeler JD, Perez EA, Wolff AC, Gralow JR, Burstein HJ, Mahmood AA, Magrinat G, Parker BA, Hart RD, Grenier D, Norton L, Hudis CA, Winer EP. Adjuvant chemotherapy in older women with early-stage breast cancer. N Engl J Med 360: 2055-65, 2009.
  • Ohorodnyk P, Eisenhauer EA, Booth CM. Clinical benefit in oncology trials: Is this a patient-centred or tumour-centred end-point? Eur J Can 45: 2249-52, 2009.
  • Pritchard KI, O'Malley F, Shepherd L, Levine MN, Tu D, Bramwell V, Andrulis I, Chia S. Response to Correspondence: "Re: Topoisomerase II Alpha and Responsiveness of Breast Cancer to Adjuvant Chemotherapy" by C. Oakman, E. Moretti, C. Sotiriou, G. Viale, A. Di Leo. J Natl Cancer Inst 101: 1736-7, 2009.
  • Quirke P, Steele R, Monson J, Grieve R, Khanna S, Couture J, O'Callaghan C, Myint AS, Bessell E, Thompson LC, Parmar M, Stephens RJ, Sebag-Montefiore D, on behalf of the MRC CRO7/NCIC-CTG CO16 trial investigators and the NCRI colorectal cancer study group. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial. Lancet 373: 821-8, 2009.
  • Sargent D, Sobrero A, Grothey A, O'Connell MJ, Buyse M, Andre T, Zheng Y, Green E, Labianca R, O'Callaghan C, Seitz JF, Francini G, Haller D, Yothers G, Goldberg R, de Gramont A. Evidence for cure by adjuvant therapy in colon cancer: Observations based on individual patient data from 20,898 patients on 18 randomized trials. J Clin Oncol 27: 872-7, 2009.
  • Sebag-Montefiore D, Stephens RJ, Steele R, Monson J, Grieve R, Khanna S, Quirke P, Couture J, de Metz C, Myint AS, Bessell E, Griffiths G, Thompson LC, Parmar M, on behalf of all the trial collaborators. Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet 373: 811-20, 2009.
  • Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJB, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, Hau P, Brandes AA, Gijtenbeek J, Marosi C, Vecht CJ, Mokhtari K, Wesseling P, Villa S, Eisenhauer E, Gorlia T, Weller M, Lacombe D, Cairncross JG, Mirimanoff R-O, on behalf of the EORTC Brain Tumour and Radiation Oncology Groups and the NCIC Clinical Trials Group. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10: 459-66, 2009.
  • Trimble EL, Abrams JS, Meyer RM, Calvo F, Cazap E, Deye J, Eisenhauer E, Fitzgerald TJ, Lacombe D, Parmar M, Seibel N, Shankar L, Swart AM, Therasse P, Vikram B, von Frenckell R, Friedlander M, Fujiwara K, Kaplan RS, Meunier F. Improving cancer outcomes through international collaboration in academic cancer treatment trials. J Clin Oncol 27: 5109-14, 2009.
  • Asmis TR, Ding K, Seymour L, Shepherd FA, Leighl NB, Winton TL, Whitehead M, Spaans JN, Graham BC, Goss GD. Age and comorbidity as independent prognostic factors in the treatment of non-small-cell lung cancer: a review of NCIC Clinical Trials Group trials. J Clin Oncol 26: 54-9, 2008.
  • Axelrod DE, Miller NA, Lickley HL, Qian J, Christens-Barry WA, Yuan Y, Fu Y, Chapman J-AW. Effect of quantitative nuclear image features on recurrence of ductal carcinoma in situ (DCIS) of the breast. Cancer Informatics 6: 99-109, 2008
  • Bezjak A, Lee CW, Ding K, Brundage M, Winton T, Graham B, Whitehead M, Johnson DH, Livingston RB, Seymour L, Shepherd FA. Quality-of-life outcomes for adjuvant chemotherapy in early-stage non-small-cell lung cancer: results from a randomized trial, JBR.10. J Clin Oncol 26: 5052-9, 2008.
  • Blanke CD, Rankin C, Demetri GD, Ryan CW, von Mehren M, Benjamin RS, Raymond AK, Bramwell VHC, Baker LH, Maki RG, Tanaka M, Hecht JR, Heinrich MC, Fletcher CDM, Crowley JJ, Borden EC. Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the Kit receptor tyrosine kinase: S0033. J Clin Oncol 26: 626-32, 2008.
  • Booth CM, Calvert AH, Giaccone G, Lobbezoo MW, Eisenhauer EA, Seymour LK, On behalf of the Task Force on Methodology for the Development of Innovative Cancer Therapies. Design and conduct of phase II studies of targeted anticancer therapy: Recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies (MDICT). Eur J Can 44: 25-9, 2008.
  • Brundage M, Bezjak A, Tu D, Palmer M, Pater J. NCIC Clinical Trials Group experience of employing patient-reported outcomes in clinical trials: an illustrative study in a palliative setting. Expert Review of Pharmacoeconomics and Outcomes Research 8: 243-53, 2008.
  • Carey MS, Bacon M, Tu D, Butler L, Bezjak A, Stuart GC. The prognostic effects of performance status and quality of life scores on progression-free survival and overall survival in advanced ovarian cancer. Gynecol Oncol 108: 100-5, 2008
  • Chan JA, Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Thomas J, Schaefer P, Whittom R, Hantel A, Goldberg RM, Warren RS, Bertagnolli M, Fuchs CS. Association of family history with cancer recurrence and survival among patients with stage III colon cancer. J Am Med Assoc 299: 2515-23, 2008.
  • Chapman J-AW, Meng D, Shepherd L, Parulekar W, Ingle JN, Muss HB, Palmer M, Yu C, Goss PE. Competing causes of death from a randomized trial of extended adjuvant endocrine therapy for breast cancer. J Natl Cancer Inst 100: 252-60, 2008.
  • Chi KN, Seymour L. Reply to the letter "About sorafenib in castration-resistant prostate cancer" by G. Colloca, F. Checcaglini and A. Venturino. Ann Oncol 19: 1813-4, 2008.
  • Chi KN, Ellard SL, Hotte SJ, Czaykwski P, Moore M, Ruether JD, Schell AJ, Taylor S, Hansen C, Gauthier I, Walsh W, Seymour L. A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer. Ann Oncol 19: 746-51, 2008.
  • Chi KN, Siu LL, Hirte H, Hotte SJ, Knox J, Kollmansberger C, Gleave M, Guns E, Powers J, Walsh W, Tu D, Eisenhauer E. A phase I study of OGX-011, a 2'methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer. Clin Cancer Res 14: 833-9, 2008.
  • Courneya KS, Booth CM, Gill S, O'Brien P, Vardy J, Friedenreich CM, Au HJ, Brundage MD, Tu D, Dhillon H, Meyer RM. The colon health and life-long exercise change trial: a randomized trial of the NCIC Clinical Trials Group. Current Oncology 15: 262-70, 2008.
  • Crump M, Gluck S, Tu D, Stewart D, Levine M, Kirkbride P, Dancey J, O'Reilly S, Shore T, Couban S, Girouard C, Marlin S, Shepherd L, Pritchard KI. Randomized trial of high-dose chemotherapy with autologous peripheral-blood stem-cell support compared with standard-dose chemotherapy in women with metastatic breast cancer: NCIC MA.16. J Clin Oncol 26: 37-43, 2008.
  • Ding K, Pater J, Whitehead M, Seymour L, Shepherd FA. Validation of treatment induced specific adverse effect as a predictor of treatment benefit: A case study of NCIC CTG BR21. Contemporary Clin Trials 29: 527-36, 2008.
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials. Lancet 371: 29-40, 2008.
  • Eisenhauer EA, El-Maraghi RH. Predicting success in phase III studies from phase II results: A new paradigm is needed (In Reply). J Clin Oncol 26: 3654-5, 2008.
  • El-Maraghi RH, Eisenhauer EA. Review of phase II trial designs used in studies of molecular targeted agents: Outcomes and predictors of success in phase III. J Clin Oncol 26: 1346-54, 2008.
  • Florescu M, Hasan B, Seymour L, Ding K, Shepherd FA. A clinical prognostic index for patients treated with erlotinib in National Cancer of Institute of Canada Clinical Trials Group study BR.21. J Thoracic Oncol 3: 590-8, 2008.
  • French AJ, Sargent DJ, Burgart LJ, Foster NR, Kabat BF, Goldberg R, Shepherd L, Windschitl HE, Thibodeau SN. Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer. Clin Cancer Res 14: 3408-15, 2008.
  • Fruh M, Rolland E, Pignon J-P, Seymour L, Ding K, Tribodet H, Winton T, LeChevalier T, Scagliotti GV, Douillard JY, Spiro S, Shepherd FA. Pooled analysis of the effect of age on adjuvant cisplatin-based chemotherapy for completely resected non-small-cell lung cancer. J Clin Oncol 26: 3573-81, 2008.
  • Goffin JR, Tu D. Phase II stopping rules that employ response rates and early progression. J Clin Oncol 26: 3715-20, 2008.
  • Gorlia T, van den Bent MJ, Hegi ME, Mirimanoff RO, Weller M, Cairncross JG, Eisenhauer E, Belanger K, Brandes AA, Allgeier A, Lacombe D, Stupp R. Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC Trial 26981-22981/CE.3. Lancet Oncol 9: 29-38, 2008.
  • Goss PE, Richardson H, Chlebowski R, Johnston D, Sarto GE, Maunsell E, Ingle JN, Alès-Martinez JE. NCIC Clinical Trials Group MAP.3 trial: Evaluation of exemestane to prevent breast cancer in postmenopausal women. Clin Breast Cancer 7: 895-900, 2007.
  • Goss PE, Ingle JN, Pater JL, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Cameron DA, Palmer MJ, Tu D. Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen. J Clin Oncol 26: 1948-55, 2008.
  • Hall WJ, Ding K. Sequential tests and estimates after overrunning based on p-value combination. Institute of Mathematical Statistics Collections 3: 33-45, 2008.
  • Hicks LK, Haynes AE, Reece DE, Walker IR, Herst JA, Meyer RM, Imrie K, Hematology Disease Site Group of the Cancer Care Ontario Program in Evidence-based Care. A meta-analysis and systematic review of thalidomide for patients with previously untreated multiple myeloma. Cancer Treat Rev 34: 442-52, 2008.
  • Ingle JN, Tu D, Pater JL, Muss HB, Martino S, Robert NJ, Piccart MJ, Castiglione M, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Cameron DA, Palmer MJ, Goss PE. Intent-to-treat analysis of the placebo-controlled trial of letrozole for extended adjuvant therapy in early breast cancer: NCIC CTG MA.17. Ann Oncol 19: 877-82, 2008.
  • Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Tebbutt NC, Chalchal H, Shapiro JD, Robitaille S, Price TJ, Shepherd L, Au H-J, Langer C, Moore MJ, Zalcberg JR. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 359: 1757-65, 2008.
  • Kelly K, Chansky K, Gaspar LE, Albain KS, Jett J, Ung YC, Lau DHM, Crowley JJ, Gandara DR. Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol 26: 2450-6, 2008.
  • Knox JJ, Gill S, Synold TW, Biagi JJ, Major P, Feld R, Cripps C, Wainman N, Eisenhauer E, Seymour L. A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the NCIC Clinical Trials Group (NCIC CTG IND.168). Invest New Drugs 26: 265-72, 2008.
  • Korn EL, Liu PY, Lee SJ, Chapman J-AW, Niedzwiecki D, Suman VJ, Moon J, Sondak VK, Atkins MB, Eisenhauer EA, Parulekar W, Markovic SN, Saxman S, Kirkwood JM. Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. J Clin Oncol 26: 527-34, 2008.
  • Lamers LM, Stupp R, van den Bent MJ, Al MJ, Gorlia T, Wasserfallen J-B, Mittmann N, Seung SJ, Crott R, Uyl-de Groot CA. Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme. Cancer 112: 1337-44, 2008.
  • Laurie SA, Gauthier I, Arnold A, Shepherd FA, Ellis PM, Chen E, Goss G, Powers J, Walsh W, Tu D, Robertson J, Puchalski TA, Seymour L. Phase I and pharmacokinetic study of daily oral AZD2171, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer: The National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 26: 1871-8, 2008.
  • Lee CW, Belanger K, Rao SC, Petrella TM, Tozer RG, Wood L, Savage KJ, Eisenhauer EA, Synold TW, Wainman N, Seymour L. A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial. Invest.New Drugs 26: 249-55, 2008.
  • Li X, Wu Y, Tu D. A Bartlett type correction for Wald test in Cox regression model. Statistics and Probability Letters 78: 2614-22, 2008.
  • Liu S, Tu D. On the applications of Fisher's least significant difference (LSD) procedure in three-arm clinical trials with survival endpoints. Drug Information Journal 42: 81-91, 2008.
  • Mamounas EP, Jeong J-H, Wickerham DL, Smith RE, Ganz PA, Land RS, Eisen A, Fehrenbacher L, Farrar WB, Atkins JN, Pajon ER, Vogel VG, Kroener JF, Hutchins LF, Robidoux A, Hoehn JL, Ingle JN, Geyer Jr CE, Costantino JP, Wolmark N. Benefit from exemestane as extended adjuvant therapy after 5 years of adjuvant tamoxifen: Intention-to-treat analysis of the National Surgical Adjuvant Breast and Bowel Project B-33 trial. J Clin Oncol 26: 1965-71, 2008.
  • Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Nelson H, Whittom R, Hantel A, Thomas J, Fuchs CS. Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803. J Clin Oncol 26: 4019-115, 2008.
  • Mitry E, Fields ALA, Bleiberg H, Labianca R, Portier G, Tu D, Nitti D, Torri V, Elias D, O'Callaghan C, Langer B, Martignoni G, Bouché O, Lazorthes F, Van Cutsem E, Bedenne L, Moore MJ, Rougier P. Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer. A pooled analysis of two randomzied trials. J Clin Oncol 26: 4906-11, 2008.
  • Muss HB, Tu D, Ingle JN, Martino S, Robert NJ, Pater JL, Whelan TJ, Palmer MJ, Piccart MJ, Shepherd LE, Pritchard KI, He Z, Goss PE. Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17. J Clin Oncol 26: 1956-64, 2008.
  • NSCLC Meta-Analyses Collaborative Group. Chemotherapy in addition to supportive care improves survival in advanced non-small-cell lung cancer: A systematic review and meta-analysis of individual patient data from 16 randomized controlled trials. J Clin Oncol 26: 4617-25, 2008.
  • Oza AM, Eisenhauer EA, Elit L, Cutz J-C, Sakurada A, Tsao MS, Hoskins PJ, Biagi J, Ghatage P, Mazurka J, Provencher D, Dore N, Dancey J, Fyles A. Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCIC IND-148. J Clin Oncol 26: 4319-25, 2008.
  • Parulekar WR, McKenzie M, Chi KN, Klotz L, Catton C, Brundage M, Ding K, Hiltz A, Meyer R, Saad F. Defining the optimal treatment strategy for localized prostate cancer patients: A survey of ongoing studies at the NCIC Clinical Trials Group. Current Oncology 15: 14-9, 2008.
  • Pater J, Tu D, Shepherd L, Ingle JN, Goss PE. Decision making in adjuvant trials in breast cancer: the NCIC CTG MA.17 trial as an example. Breast Cancer Res Treat 108: 265-9, 2008.
  • Pater JL, Goss P, Meyer R. Stopping trials for benefit can (sometimes) benefit patients (Correspondence). J Clin Oncol 26: 2787-8, 2008.
  • Pignon J-P, Tribodet H, Scagliotti GV, Douillard J-Y, Shepherd FA, Stephens RJ, Dunant A, Torri V, Rosell R, Seymour L, Spiro SG, Rolland E, Fossati R, Aubert D, Ding K, Waller D, LeChevalier T. Lung adjuvant cisplatin evaluation: A pooled analysis by the LACE Collaborative Group. J Clin Oncol 26: 3552-9, 2008.
  • Schneider BP, Wang M, Radovich M, Sledge GW, Badve S, Thor A, Flockhart DA, Hancock B, Davidson N, Gralow J, Dickler M, Perez EA, Cobleigh M, Shenkier T, Edgerton S, Miller KD. Association of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor-2 Genetic Polymorphisms With Outcome in a Trial of Paclitaxel Compared With Paclitaxel Plus Bevacizumab in Advanced Breast Cancer: ECOG 2100. J Clin Oncol 26: 4672-8, 2008.
  • Wheatley-Price P, Ding K, Seymour L, Clark GM, Shepherd FA. Erlotinib for advanced non-small-cell lung cancer in the elderly: An analysis of the NCIC Clinical Trials Group study BR.21. J Clin Oncol 26: 2350-7, 2008.
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  • Byrd JC, Rai K, Peterson BL, Appelbaum FR, Morrison VA, Kolitz JE, Shepherd L, Hines JD, Schiffer CA, Larson RA. Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 105: 49-53, 2005.
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  • Chi KN, Eisenhauer E, Fazli L, Jones EC, Goldenberg L, Powers J, Tu D, Gleave ME. A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst 97: 1287-96, 2005.
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  • Delaunoit T, Alberts SR, Sargent DJ, Green E, Goldberg RM, Krook J, Fuchs C, Ramanathan RK, Williamson SK, Morton RF, Findlay BP. Chemotherapy permits resection of metastatic colorectal cancer: experience from Intergroup N9741. Ann Oncol 16: 425-9, 2005.
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  • Duncan G, Epstein J, Tu D, El-Sayed S, Bezjak A, Ottaway J, Pater J. Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis. Head & Neck 27: 421-8, 2005.
  • Ernst DS, Eisenhauer E, Wainman N, Davis M, Lohmann R, Baetz T, Belanger K, Smylie M. Phase II study of perifosine in previously untreated patients with metastatic melanoma. Invest New Drugs 23(6): 569-75, 2005.
  • Gelmon KA, Belanger K, Soulieres D, Britten C, Chia S, Charpentier D, Chi K, Powers J, Walsh W, Seymour L. A phase I study of T900607 given once every 3 weeks in patients with advanced refractory cancers; NCIC Clinical Trials Group (NCIC-CTG) IND130. Invest New Drugs 23: 445-53, 2005.
  • Gilron I, Tu D. Response to comment by Dahl and Kehlet (Letters/Correspondence). Pain 115: 219, 2005.
  • Goel R, Chouinard E, Stewart DJ, Huan S, Hirte H, Stafford S, Waterfield B, Roach J, Lathia C, Agarwal V, Humphrey R, Walsh W, Matthews S, Seymour L. An NCIC CTG phase I/pharmacokinetic study of the matrix metalloproteinase and angiogenesis inhibitor BAY 12-9566 in combination with 5-fluorouracil/leucovorin. Invest New Drugs 23: 63-71, 2005.
  • Goffin J, Baral S, Tu D, Nomikos D, Seymour L. Objective responses in patients with malignant melanoma or renal cell cancer in early clinical studies do not predict regulatory approval. Clin Cancer Res 11: 5928-34, 2005.
  • Goss G, Hirte H, Miller WHJr, Lorimer IAJ, Stewart D, Batist G, Parolin DAE, Hanna P, Stafford S, Friedmann J, Walsh W, Matthews S, Douglas L, Seymour LK. A phase I study of oral ZD1839 given daily in patients with solid tumors: IND.122, a study of the Investigational New Drug Program of the NCIC Clinical Trials Group. Invest New Drugs 23: 147-55, 2005.
  • Goss PE, Ingle JN, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Tu D, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Cameron DA, Palmer MJ, Pater JL. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. J Natl Cancer Inst 97: 1262-71, 2005.
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  • Hegi ME, Diserens A-C, Gorlia T, Hamou M-F, de Tribolet N, Weller M, Kros JM, Hainfeller JA, Mason W, Mariani L, Bromberg JEC, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R. MGMT gene silencing and benefit form temozolomide in gliobalstoma. N Engl J Med 352: 997-1003, 2005.
  • Hirte H, Stewart D, Goel R, Chouinard E, Huan S, Stafford S, Waterfield B, Matthews S, Lathia C, Schwartz B, Agarwal V, Humphrey R, Seymour L. An NCIC-CTG phase I dose escalation pharmacokinetic study of the matrix metalloproteinase inhibitor BAY 12-9566 in combination with doxorubicin. Invest New Drugs 23: 437-43, 2005.
  • Karapetis C, Jonker D, O'Callaghan C. Cetuximab plus BSC versus BSC alone in the treatment of metastatic EGFR-positive colorectal cancer. Signal 6: 15-7, 2005.
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  • Lê LH, Moore MJ, Siu LL, Oza AM, MacLean M, Fisher B, Chaudhary A, de Alwis DP, Slapak C, Seymour L. Phase I study of the multidrug resistance inhibitor zosuquidar administered in combination with vinorelbine in patients with advanced solid tumours. Cancer Chemother Pharmacol 56: 154-60, 2005.
  • Leighl NB, Paz-Ares L, Douillard J-Y, Peschel C, Arnold A, Depierre A, Santoro A, Betticher DC, Gatzemeier U, Jassem J, Crawford J, Tu D, Bezjak A, Humphrey JS, Voi M, Galbraith S, Hann K, Seymour L, Shepherd FA. Randomized phase III study of matrix metalloproteinase inhibitor BMS-275291 in combination with paclitaxel and carboplatin in advanced non-small cell lung cancer: NCIC Clinical Trials Group Study BR.18. J Clin Oncol 23: 2831-9, 2005.
  • Levine MN, Pritchard KI, Bramwell VHC, Shepherd LE, Tu D, Paul N. Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: Update of NCIC Clinical Trials Group trial MA5 Trial MA5. J Clin Oncol 23: 5166-70, 2005.
  • Lukka H, Hayter C, Julian JA, Warde P, Morris WJ, Gospodarowicz M, Levine M, Sathya J, Choo R, Prichard H, Brundage M, Kwan W. Randomized Trial Comparing Two Fractionation Schedules for Patients With Localized Prostate Cancer. J Clin Oncol 23: 6132-8, 2005.
  • MacKenzie MJ, Hirte HW, Goss G, Maroun J, Goel R, Major PP, Miller WHJr, Panasci L, Lorimer IAJ, Batist G, Matthews S, Douglas L, Seymour L. A phase II trial of ZD1839 (IressaTM) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer. Invest New Drugs 23: 165-70, 2005.
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  • Osoba D, Bezjak A, Brundage M, Zee B, Tu D, Pater J, for the Quality of Life Committee of the NCIC CTG. Analysis and interpretation of health-related quality-of-life data from clinical trials: basic approach of the NCIC Clinical Trials Group. Eur J Can 41: 280-7, 2005.
  • Ouyang Y, Li D, Pater JL, Levine M. The importance of temporal effects in evaluating the prognostic impact of joint ERPR expression in premenopausal women with node-positive breast cancer. Breast Cancer Res Treat 92: 115-23, 2005.
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  • Pfisterer J, Vergote I, du Bois A, Eisenhauer E, for the AGO-OVAR,NCIC CTG & EORTC GCG. Combination therapy with gemcitabine and carboplatin in recurrent ovarian cancer. Int J Gynecol Cancer 15: 36-41, 2005.
  • Piccart-Gebhart MJ, Procter M, Leyland-Jones B, Goldhirsch A, Untch M, Smith I, Gianni L, Baselga J, Bell R, Jackisch C, Cameron D, Dowsett M, Barrios CH, Steger G, Huang C-S, Andersson M, Inbar M, Lichinitser M, Lang I, Nitz U, Iwata H, Thomssen C, Lohrisch C, Suter TM, Rüschoff J, Sütõ T, Greatorex V, Ward C, Straehle C, McFadden E, Dolci S, Gelber RD. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 353(16): 1659-72, 2005.
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  • Quinn M, Avall-Lundqvist E, du Bois A, Vermorken J, Parmar M, Pfisterer J, Stuart G, Thigpen T, Neijt J, On behalf of the Gynecological Cancer Intergroup (GCIG) Consensus Working Group. History, scope and methodology of the 3rd international consensus workshop on ovarian cancer 2004. Ann Oncol 16: viii5-viii6, 2005.
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  • Tu D, Chen J, Shi P, Wu Y. A Bartlett type correction for Rao's score test in Cox regression model. The Indian Journal of Statistics 67: 722-35, 2005.
  • Van Meerbeeck JP, Gaafar R, Manegold C, Van Klaveren RJ, Van Marck EA, Vincent M, Legrand C, Bottomley A, Debruyne C, Giaccone G. Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: An intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the NCIC Clinical Trials Group. J Clin Oncol 23: 6881-9, 2005.
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  • Wasan KM, Goss PE, Pritchard PH, Shepherd L, Palmer MJ, Liu S, Tu D, Ingle JN, Heath M, DeAngelis D, Perez EA. The influence of letrozole on serum lipid concentrations in postmenopausal women with primary breast cancer who have completed 5 years of adjuvant tamoxifen (NCIC CTG MA.17L). Ann Oncol 16: 707-15, 2005.
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  • Whelan T, Goss PE, Ingle JN, Pater JL, Tu D, Pritchard K, Liu S, Shepherd LE, Palmer M, Robert NJ, Martino S, Muss HB. Assessment of quality of life in MA.17: A randomized, placebo-controlled trial of letrozole after 5 years of tamoxifen in postmenopausal women. J Clin Oncol 23: 6931-40, 2005.
  • Winquist E, Moore MJ, Chi K, Ernst S, Hirte H, North S, Powers J, Walsh W, Boucher T, Patton R, Seymour L. A multinomial phase II study of Lonafarnib (SCH 66336) in patients with refractory urothelial cancer. Urologic Oncology 23: 143-9, 2005.
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  • Ataman F, Poortmans P, Stupp R, Fisher B, Mirimanoff RO. Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review. Eur J Can 40: 1724-30, 2004.
  • Bezjak A, Tu D, Bacon M, Osoba D, Zee B, Stuart G, Roy J-A, Piccart M, Eisenhauer E. Quality of life in ovarian cancer patients: comparison of paclitaxel plus cisplatin, with cyclophosphamide plus cisplatin in a randomized study. J Clin Oncol 22: 4595-603, 2004.
  • Byrd JC, Rai K, Peterson B, Appelbaum F, Morrison VA, Kolitz J, Shepherd L, Hines J, Schiffer C, Larson R. The addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 2004.
  • Burdette-Radoux S, Tozer RG, Lohmann RC, Quirt I, Ernst S, Walsh W, Wainman N, Colevas AD, Eisenhauer EA. Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma. Invest New Drugs 22(3): 315-22, 2004.
  • Butler L, Bacon M, Carey M, Zee B, Tu D, Bezjak A. Determining the relationship between toxicity and quality of life in an ovarian cancer chemotherapy clinical trial. J Clin Oncol 22(12): 2461-8, 2004.
  • Crump M, Baetz T, Couban S, Belch A, Marcellus D, Howson-Jan K, Imrie K, Myers R, Adams G, Ding K, Paul N, Shepherd L, Iglesias J, Meyer R. Gemcitabine, dexamethasone and cisplatin in patients with recurrent or refractory aggressive histology B-cell non-Hodgkin lymphoma. A phase II study by the NCIC Clinical Trials Group (NCIC-CTG). Cancer 101: 1835-42, 2004.
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  • Douillard J-Y, Peschel C, Shepherd F, Paz-Ares L, Arnold A, Davis M, Tonato M, Smylie M, Tu D, Voi M, Humphrey J, Ottaway J, Young K, Van Vreckem A, Seymour L. Randomized phase II feasibility study of combining the matrix metalloproteinase inhibitor BMS-275291 with paclitaxel plus carboplatin in advanced non-small cell lung cancer. Lung Cancer 46: 361-8, 2004.
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  • Gelmon K, Hirte H, Fisher B, Walsh W, Ptaszynski M, Hamilton M, Onetto N, Eisenhauer E. Phase I study of OSI-211 given as an intravenous infusion days 1, 2 and 3 every three weeks in patients with solid cancers. Invest New Drugs 22: 263-75, 2004.
  • Gill S, Loprinzi CL, Sargent DJ, Thomé SD, Alberts SR, Haller DG, Benedetti J, Francini G, Shepherd LE, Seitz JF, Labianca R, Chen W, Cha SS, Heldebrant MP, Goldberg RM. Pooled Analysis of Fluorouracil-Based Adjuvant Therapy for Stage II and III Colon Cancer: Who Benefits and by How Much? J Clin Oncol 22(10): 1797-806, 2004.
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  • Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, Findlay BP, Pitot HC, Alberts SR. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 22: 23-30, 2004.
  • Goss PE, Ingle JN, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Tu D, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Therasse P, Palmer MJ, Pater JL. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. Obstetrical & Gynecological Survey 59: 201-3, 2004.
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  • Le LH, Erlichman C, Pillon L, Thiessen JJ, Day A, Wainman N, Eisenhauer EA, Moore MJ. Phase I and pharmacokinetic study of fostriecin given as an intervenous bolus daily for five consecutive days. Invest New Drugs 22(2): 159-67, 2004.
  • Ma BBY, Oza A, Eisenhauer E, Stanimir G, Carey M, Chapman W, Latta E, Sidhu K, Powers J, Walsh W, Fyles A. The activity of letrozole in patients with advanced or recurrent endometrial cancer and correlation with biological markers - a study of the National Cancer Institute of Canada Clinical Trials Group. Int J Gynecol Cancer 14: 650-8, 2004.
  • MacKenzie MJ, Hirte HW, Siu LL, Gelmon K, Ptaszynski M, Fisher B, Eisenhauer E. A phase I study of OSI-211 and cisplatin as intravenous infusions given on days 1, 2 and 3 every 3 weeks in patients with solid cancers. Ann Oncol 15(4): 665-70, 2004.
  • Martenson JA, Jr., Willett CG, Sargent DJ, Mailliard JA, Donohue JH, Gunderson LL, Thomas CR, Jr., Fisher B, Benson AB, III, Myerson R, Goldberg RM. Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: Results of intergroup protocol 0130. J Clin Oncol 22: 3277-83, 2004.
  • Parulekar WR, Eisenhauer EA. Phase I trial design for solid tumour studies of targeted, non-cytotoxic agents: theory and practice. J Natl Cancer Inst 96(13): 990-7, 2004.
  • Reyno L, Seymour L, Tu D, Dent S, Gelmon K, Walley B, Pluzanska A, Gorbunova V, Garin A, Jassem J, Pienkowski T, Dancey J, Pearce L, MacNeil M, Marlin S, Lebwohl D, Voi M, Pritchard K. Phase III study of N,N-Diethyl-2-[4-(Phenylmethyl) Phenoxy] Ethanamine (BMS-217380-01) combined with doxorubicin versus doxorubicin alone in metastatic/recurrent breast cancer: NCIC Clinical Trials Group Study MA.19. J Clin Oncol 22(2): 269-76, 2004.
  • Rustin GJS, Quinn M, Thigpen T, du Bois A, Pujade-Lauraine E, Jakobsen A, Eisenhauer E, Sagae S, Greven K, Vergote I, Cervantes A, Vermorken J. New guidelines to evaluate the response to treatment in solid tumors (ovarian cancer) (Correspondence). J Natl Cancer Inst 96(6): 487-8, 2004.
  • Stewart AK, Chen CI, Howson-Jan K, White D, Roy J, Kovacs MJ, Shustik C, Sadura A, Shepherd L, Ding K, Meyer RM, Belch AR. Results of a multi-center randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant. Clin Cancer Res 10: 8170-6, 2004.
  • Advanced Bladder Cancer (ABC) Meta-analysis Collaboration. Neoadjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis. Lancet 361: 1927-34, 2003.
  • Bacon M, James K, Zee B. A comparison of the incidence, duration and degree of the neurological toxicities of cisplatin-paclitaxel (PT) and cisplatin-cyclophosphamide (PC). Int J Gynecol Cancer 13: 428-34, 2003.
  • Baetz T, Belch A, Couban S, Imrie K, Yau J, Myers R, Ding K, Paul N, Shepherd L, Iglesias J, Meyer R, Crump M. Gemcitabine, dexamethasone and cisplatin is an active and non-toxic chemotherapy regimen in relapsed or refractory Hodgkin's disease: a phase II study by the NCIC Clinical Trials Group. Ann Oncol 14(12): 1762-7, 2003.
  • Belanger K, MacDonald D, Cairncross G, Gertler S, Forsyth P, Burdette-Radoux S, Bergeron J, Soulieres D, Ludwin S, Wainman N, Eisenhauer E. A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma. Invest New Drugs 21(4):473-80, 2003.
  • Biagi J, Eisenhauer E. Systemic treatment policies in ovarian cancer: the next 10 years. Int J Gynecol Cancer 13(suppl 2): 231-40, 2003.
  • Bonnefoi H, Diebold-Berger S, Therasse P, Hamilton A, van de Vijver M, MacGrogan G, Shepherd L, Amaral N, Duval D, Drijkoningen D, Larsimont D, Piccart M. Locally advanced/inflammatory breast cancers treated with intensive epirubicin-based neoadjuvant chemotherapy: are there molecular markers in the primary tumour that predict for 5-year clinical outcome? Ann Oncol 14(3): 406-13, 2003.
  • Brundage M, Leis A, Bezjak A, Feldman-Stewart D, Degner L, Velji K, Zetes-Zanatta L, Tu D, Ritvo P, Pater J. Cancer patients' preferences for communicating clinical trial quality of life information: a qualitative study. Quality of Life Research 12: 395-404, 2003.
  • Crump M, Tu D, Shepherd L, Levine M, Bramwell V, Pritchard K. Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the NCIC Clinical Trials Group. J Clin Oncol 21(16): 3066-71, 2003.
  • Daneshmand M, Parolin DAE, Hirte HW, Major P, Goss G, Stewart D, Batist G, Miller WHJr, Matthews S, Seymour L, Lorimer IAJ. A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. Clin Cancer Res 9: 2457-64, 2003.
  • Davis AJ, Gelmon KA, Siu LL, Moore MJ, Britten CD, Mistry N, Klamut H, D'Aloisio S, MacLean M, Wainman N, Ayers D, Firby P, Besterman JM, Reid GK, Eisenhauer EA. Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks. Invest New Drugs 21: 85-97, 2003.
  • Ding K. A lower confidence bound for the change point after a sequential CUSUM test. Journal of Statistical Planning and Inference 115: 311-26, 2003.
  • Duggan DB, Petroni GR, Johnson JL, Glick JH, Fisher RI, Connors J, Canellos GP, Peterson BA. Randomized comparison of ABVD and MOPP/ABV hybrid for the treatment of advanced Hodgkin's disease: report of an intergroup trial. J Clin Oncol 21(4): 607-14, 2003.
  • Eckhardt G, Eisenhauer E, Parulekar WR, Pazdur R, Hirschfeld S. Developmental theraputics: Successes and failures of clinical trial designs of targeted compounds. American Society of Clinical Oncology, Educational Book 209-19, 2003.
  • Eisenhauer E. Front-Line chemotherapy for ovarian cancer: which regimen and which route? American Society of Clinical Oncology, Educational Book 376-84, 2003.
  • Ernst DS, Tannock IF, Winquist EW, Venner PM, Reyno L, Moore MJ, Chi K, Ding K, Elliott C, Parulekar W. Randomized double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain. J Clin Oncol 21: 3335-42, 2003.
  • Evans WK, Coyle D, Gafni A, Walker H and the National Cancer Institute of Canada Clinical Trials Group Working Group on Economic Analysis. Which cancer clinical trials should be considered for economic evaluation? Selection criteria from the NCIC Clinical Trials Group's Working Group on Economic Analysis. Chronic Dis Can 24(4), 102-107, 2003.
  • Gelmon KA, Vandenberg TA, Panasci L, Norris B, Crump M, Douglas L, Walsh W, Matthews SJ, Seymour LK. A phase II study of ZD0473 given as a short infusion every 3 weeks to patients with advanced or metastatic breast cancer: a NCIC Clinical Trials Group trial, IND 129. Ann Oncol 14: 543-8, 2003.
  • Goss PE, Ingle JN, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Tu D, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Therasse P, Palmer MJ, Pater JL. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 349(19):1793-1802, 2003.
  • Gridelli C, Gallo C, Shepherd F.A., Illiano A, Piantedosi F, Robbiati S, Manzione L, Barbera S, Frontini L, Veltri E, Findlay B, Cigolari S, Myers R, Ianniello G, Gebbia V, Gasparini G, Fava S, Hirsh V, Bezjak A, Seymour L, Perrone F. Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: A phase III trial of the Italian GEMVIN investigators and the NCIC Clinical Trials Group. J Clin Oncol 21(16): 3025-34, 2003.
  • Kouroukis CT, Belch A, Crump M, Eisenhauer E, Gascoyne RD, Meyer R, Lohmann R, Lopez P, Powers J, Turner R, Connors JM. Flavopiridol in untreated or relapsed mantle-cell lymphoma: Results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 21(9): 1740-1745, 2003.
  • Kristensen GB, Vergote I, Stuart G, del Campo JM, Kaern J, Lopez AB, Eisenhauer E, Aavall-Lundquist E, Ridderheim M, Havsteen H, Mirza MR, Scheistroen M, Vrdoljak E. First line treatment of ovarian cancer FIGO stages IIb-IV with paclitaxel/epirubicin/carboplatin versus paclitaxel/carboplatin. Int J Gynecol Cancer 13(suppl 2): 172-7, 2003.
  • Moore M, Hamm J, Dancey J, Eisenberg PD, Dagenais M, Fields A, Hagan K, Greenberg B, Colwell B, Zee B, Tu D, Ottaway J, Humphrey R, Seymour L. Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the NCIC Clinical Trials Group. J Clin Oncol 21(17): 3296-302, 2003.
  • Olivotto I, Chua B, Elliott EA, Parda DS, Pierce LJ, Shepherd L, Vallow LA, White JR, Whelan T. A clinical trial of breast radiation therapy versus breast plus regional radiation therapy in early-stage breast cancer: the MA20 trial. Clin Breast Cancer 4(5): 361-3, 2003.
  • Oza AM, Elit L, Swenerton K, Faught W, Ghatage P, Carey M, McIntosh L, Dorr A, Holmlund JT, Eisenhauer E. Phase II study of CGP 69846A (ISIS 5132) in recurrent epithelial ovarian cancer. An NCIC clinical trials group study (NCIC IND.116). Gynecol.Oncol 89(1): 129-133, 2003.
  • Pater JL, Parulekar WR. Ovarian ablation as adjuvant therapy for premenopausal women with breast cancer - another step forward. J Natl Cancer Inst 95(24): 1811-2, 2003.
  • Pater JL, Pritchard KI. Optimal chemotherapy for women with breast cancer: the plot thickens. J Clin Oncol 21(6): 963-4, 2003.
  • Piccart MJ, Bertelsen K, Stuart G, Cassidy J, Mangioni C, Simonsen E, James K, Kaye S, Vergote I, Blom R, Grimshaw R, Atkinson R, Swenerton K, Trope C, Nardi M, Kaern J, Tumolo S, Timmers P, Roy JA, Lhoas F, Lidvall B, Bacon M, Birt A, Andersen J, Zee B, Paul J, Pecorelli S, Baron B, McGuire W. Long-term follow-up confirms a survival advantage of the paclitaxel-cisplatin regimen over the cyclophosphamide-cisplatin combination in advanced ovarian cancer. Int J Gynecol Cancer 13(Suppl 2): 144-8, 2003.
  • Pritchard K, Levine M, Tu D. neu/erbB-2 overexpression and response to hormonal therapy in premenopausal women in the adjuvant breast cancer setting: Will it play in Peoria? Part II. J Clin Oncol 21(3): 399-400, 2003.
  • Ribic CM, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, Hamilton SR, Laurent-Puig P, Gryfe R, Shepherd LE, Tu D, Redston M, Gallinger S. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 349: 247-57, 2003.
  • Rothenberg M, Liu PY, Braly PS, Wilczynski S, Hannigan EV, Wadler S, Stuart G, Jiang C, Markman M, Alberts DS. Combined intraperitoneal and intravenous chemotherapy for women with optimally debulked ovarian cancer: resultsfrom an intergroup phase II trial. J Clin Oncol 21(7): 1313-9, 2003.
  • Seymour L. Epidermal growth factor receptor inhibitors: An update on their development as cancer therapeutics. Current Opinion in Investigational Drugs 4(6): 658-66, 2003.
  • Sridhar SS, Seymour L, Shepherd FA. Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer. Lancet Oncol 4(7): 397-406, 2003.
  • Stadler W, Lerner SP. Perioperative chemotherapy in locally advanced bladder cancer (Commentary). Lancet 361: 1922-3, 2003.
  • Stewart DJ, Donehower RC, Eisenhauer EA, Wainman N, Shah AK, Bonfils C, MacLeod AR, Besterman JM, Reid GK. A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly. Ann Oncol 14: 766-74, 2003.
  • Therasse P, Mauriac L, Welnicka-Jaskiewicz M, Bruning P, Cufer T, Bonnefoi H, Tomiak E, Pritchard KI, Hamilton A, Piccart MJ. Final results of a randomized phase III trial comparing cyclophosphamide, epirubicin, and fluorouracil with a dose-intensified epirubicin and cyclophosphamide + filgrastim as neoadjuvant treatment in locally advanced breast cancer: An EORTC-NCIC-SAKK Multicenter Study. J Clin Oncol 21: 843-50, 2003.
  • Townsley CA, Chi K, Ernst DS, Belanger K, Tannock I, Bjarnason GA, Stewart D, Goel R, Ruether JD, Siu LL, Jolivet J, McIntosh L, Seymour L, Moore MJ. Phase II study of troxacitabine (BCH-4556) in patients with advanced and/or metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada-Clinical Trials Group. J Clin Oncol 21(8): 1524-9, 2003.
  • Tsao MN, Sultanem K, Chiu D, Copps F, Dixon P, Easton D, Haddad P, Hayter C, Hoegler D, Wong R. Supportive care management of brain metastases: What is known and what we need to know. Conference proceedings of the National Cancer Institute of Canada workshop on symptom control in radiation oncology. Clin Oncol 15: 429-34, 2003.
  • Voskoglou-Nomikos T, Pater JL, Seymour L. Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models. Clin Cancer Res 9: 4227-39, 2003.
  • Wright JR, McKenzie M, DeAngelis C, Foroudi F, Paul N, Rajaraman M, Wong F, Wong R, Wong KSR. Radiation induced mucositis: co-ordinating a research agenda. Clin Oncol 15(8): 473-7, 2003.
  • Wu J, Bezjak A, Chow E, Cross P, Genest P, Grant N, Kirkbride P, Roy I, Whelan T, Fitzgibbon E, Wong R. A consensus development approach to define national research priorities in bone metastases: proceedings from NCIC CTG workshop. Clin Oncol 15(8): 496-499. 2003.
  • Yee K, Pater J, Pho L, Zee B, Siu L. Enrollment of older patients in cancer treatment trials in Canada: why is age a barrier? J Clin Oncol 21(8): 1618-23, 2003.
  • Belanger K, Moore M, Baker SD, Dionne J, MacLean M, Jolivet J, Siu L, Soulieres D, Wainman N, Seymour L. Phase I and pharmacokinetic study of a novel L-nucleoside analog troxacitabine given as a 30-minute infusion every 21 days. J Clin Oncol 20(10): 2567-74, 2002.
  • Bezjak A, Dixon P, Brundage M, Tu D, Palmer M, Blood P, Grafton C, Lochrin C, Leong C, Mulroy L, Smith C, Wright J, Pater J. Randomized phase III trial of single versus fractionated thoracic radiation in the palliation of patients with lung cancer (NCIC CTG SC.15). Int J Rad Oncol Biol Phys 54(3): 719-28, 2002.
  • Cripps MC, Figueredo AT, Oza AM, Taylor MJ, Fields AL, Holmlund JT, MacIntosh LW, Geary RS, Eisenhauer EA. Phase II randomized study of ISIS 3521 and ISIS 5132 in patients with locally advanced or metastatic colorectal cancer: a National Cancer Institute of Canada Clinical Trials Group Study Clin Cancer Res 8: 2188-92, 2002.
  • Crump M, Couban S, Meyer R, Rudinskas L, Zanke B, Gluck S, Maksymiuk A, Hoskins P, Matthews S, Eisenhauer E. Phase II study of sequential topotecan and etoposide in patients with intermediate grade non-Hodgkin's lymphoma: a NCIC Clinical Trials Group study. Leukemia & Lymphoma 43(8): 1595-1601, 2002.
  • Davis A, O'Sullivan B, Bell R, Turcotte R, Catton C, Wunder J, Chabot P, Hammond A, Benk V, Isler M, Freeman C, Goddard K, Bezjak A, Kandel R, Sadura A, Day A, James K, Tu D, Pater J, Zee B. Function and health status outcomes in a randomized trial comparing preoperative and postoperative radiotherapy in extremity soft tissue sarcoma. J Clin Oncol 20(22): 4472-7, 2002.
  • El-Sayed S, Nabid A, Shelley W, Hay J, Balogh J, Gelinas M, MacKenzie R, Read N, Berthelet E, Lau H, Epstein J, Delvecchio P, Ganguly PK, Wong F, Burns P, Tu D, Pater J. Prophylaxis of radiation-associated mucositis in conventionally treated patients with head and neck cancer: a double blind, phase III, randomized, controlled trial evaluating the clinical efficacy of an antimicrobial lozenge using a validated mucositis scoring system. J Clin Oncol 20(19): 3956-63, 2002.
  • Freidlin B, Dancey J, Korn E, Zee B, Eisenhauer E. Multinomial phase II trial designs. J Clin Oncol 20(2): 599, 2002.
  • Fung KFM, Eisenhauer E, Elit L, Hirte H, Rosen B. Chemotherapy for recurrent epithelial ovarian cancer previously treated with platinum - a systemic review of the evidence from randomized trials. European J Gyne Oncol 23(2): 2002.
  • Goffin J, Eisenhauer E. DNA methyltransferase inhibitors - state of the art. Ann Oncol 13: 1699-716, 2002.
  • O'Sullivan B, Davis A, Turcotte R, Bell R, Catton C, Chabot P, Wunder J, Kandel R, Goddard K, Sadura A, Pater J, Zee B. Pre-operative versus postoperative radiotherapy in soft tissue sarcoma of the limbs: a randomised trial. Lancet 359(9325): 2235-41, 2002.
  • Parulekar W, Eisenhauer E. Novel endpoints and design of early clinical trials. Ann Oncol 13 (Suppl. 4): 139-43, 2002.
  • Pearcey R, Brundage M, Drouin P, Jeffrey J, Johnston D, Lukka H, MacLean G, Souhami L, Stuart G, Tu D. Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. J Clin Oncol 20(4): 966-72, 2002.
  • Quirt I, Bodurtha A, Lohmann R, Rusthoven J, Belanger K, Young V, Wainman N, Steward W, Eisenhauer E. Phase II study of marimastat (BB-2516) in malignant melanoma: a clinical and tumor biopsy study of the NCIC Clinical Trials Group. Invest New Drugs 20: 431-7, 2002.
  • Roche K, Paul N, Smuck B, Whitehead M, Zee B, Pater J, Hiatt M, Walker H. Factors affecting workload of cancer clinical trials: results of a multicenter study of the NCIC Clinical Trials Group. J Clin Oncol 20(2): 545-56, 2002.
  • Seymour L. New targets and new therapeutics. Oncologica Clinica 7: 717-8, 2002.
  • Seymour L. Non-small cell cancer: Current approaches and future treatment. Oncologica Clinica 7: 718-9, 2002.
  • Seymour L. The design of clinical trials for new molecularly targeted compounds: progress and new initiatives. Current Pharmaceutical Design 8(25): 2279-84, 2002.
  • Seymour L. Gefitinib: A Viewpoint (Guest Commentary). Drugs 62: 2249, 2002.
  • Shepherd FA, Giaccone G, Seymour L, Debruyne C, Bezjak A, Hirsh V, Smylie M, Rubin S, Martins H, Lamont A, Krzakowski M, Sadura A, Zee B. Prospective, randomized, double-blind, placebo controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: A trial of the NCIC Clinical Trials Group and the European Organization for Research and Treatment of Cancer. J Clin Oncol 20(22): 4434-9, 2002.
  • Stadler W, Hayden A, von der Maase H, Roychowdhury D, Dogliotti L, Seymour L, Kaufmann D, Moore M. Long-term survival in phase II trials of gemcitabine plus cisplatin for advanced transitional cell cancer. Urologic Oncology 7: 153-7, 2002.
  • Swenerton K, Jeffrey J, Stuart G, Roy M, Krepart G, Carmichael J, Drouin P, Stanimir R, O'Connell G, MacLean G, Kirk M, Canetta R, Koski B, Shelley W, Zee B, Pater J. Cisplatin-cyclophosphamide versus carboplatin-cyclophosphamide in advanced ovarian cancer: A randomized phase III study of the NCIC Clinical Trials Group. Classic Papers & Current Comments 7(1): 53-62, 2002.
  • Tolcher AW, Reyno L, Venner PM, Ernst SD, Moore M, Geary RS, Chi K, Hall S, Walsh W, Dorr A, Eisenhauer E. A randomized phase II and pharmacokinetic study of the antisense oligonucleotides ISIS 3521 and ISIS 5132 in patients with hormone-refractory prostate cancer. Clin Cancer Res 8: 2530-5, 2002.
  • Tozer RG, Burdette-Radoux S, Belanger K, Davis ML, Lohmann RC, Rusthoven JR, Wainman N, Zee B, Seymour L. A randomized phase II study of two schedules of bryostatin 1 (NSC339555) in patients with advanced malignant melanoma. Invest New Drugs 20: 407-12, 2002.
  • Trudeau M, Stuart G, Hirte H, Drouin P, Plante M, Bessette P, Dulude H, Lebwohl D, Fisher B, Seymour L. A phase II trial of JM-216 in cervical cancer: an NCIC CTG study. Gynecol Oncol 84(2): 327-31, 2002.
  • Weeks JC, Nelson H, Gelber S, Sargent D, Schroeder G. Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer. J Am Med Assoc 287(3): 321-8, 2002.
  • Wigle DA, Jurisica I, Radulovich N, Pintilie M, Rossant J, Liu N, Lu C, Woodgett J, Seiden I, Johnston M, Keshavjee S, Darling G, Winton T, Breitkreutz BJ, Jorgenson P, Tyers M, Shepherd FA, Tsao MS. Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Research 62: 3005-8, 2002.
  • Dent S, Zee B, Dancey J, Hanauske A, Wanders J, Eisenhauer E. Application of a new multinomial phase II stopping rule using response and early-progression. J Clin Oncol 19(3): 785-91, 2001.
  • Duivenvoorden WCM, Hirte HW, Singh G. Quantification of matrix metalloproteinase activity in plasma of patients enrolled in a BAY 12-9566 phase I study. Int J Cancer 91(6): 857-62, 2001.
  • Eisenhauer E. From the molecule to the clinic -- inhibiting HER2 to treat breast cancer. N Engl J Med 344(11): 841-2, 2001.
  • Eisenhauer E, Dancey J. Impact of new non-cytotoxics in the treatment of ovarian cancer. Int J Gynecol Cancer 11(Suppl.1): 68-72, 2001.
  • Gortzak E, Azzarelli A, Buesa J, Bramwell VHC, van Coevorden F, van Geel AN, Ezzat A, Santoro A, Oosterhuis JW, van Glabbeke M, Kirkpatrick A, Verweij J, the EORTC Soft Tissue Bone Sarcoma Group and the NCIC Clinical Trials Group/Canadian Sarcoma Group. A randomised phase II study on neo-adjuvant chemotherapy for 'high risk' adult soft-tissue sarcoma. Eur J Can 37(9): 1096-103, 2001.
  • Kiebert G, Wait S, Bernhard J, Bezjak A, Cella D, Day R, Houghton J, Moinpour C, Scott C, Stephens R. Practice and policy of measuring quality of life and health economics in cancer clinical trials: A survey among co-operative trial groups. Quality of Life Research 9: 1073-80, 2001.
  • Knowling M, Browman G, Siu L, Khoo K, Cooke A, Tannock I, Klaassen D, Cripps C, Goss G, Matthews S, Clarke R, Seymour L. A NCIC Clinical Trials Group phase II study of eniluracil (776C85) and oral 5-fluorouracil in patients with advanced squamous cell head and neck cancer. Ann Oncol 12: 919-22, 2001.
  • Levine M, Bramwell V, Pritchard K, Norris B, Shepherd L, Abu-Zahra H, Findlay B, Warr D, Bowman D, Myles J, Arnold A, Vandenberg T, MacKenzie R, Robert J, Ottaway J, Burnell M, Williams CKO, Tu D. Randomized trial of cyclophosphamide, epirubicin, fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, fluorouracil in premenopausal women with node positive breast cancer. Classic Papers & Current Comments 5: 694-702, 2001.
  • Murray N, Livingston R, Shepherd F, James K, Zee B, Langleben A, Kraut M, Bearden J, Goodwin J, Grafton C, Turrisi A, Walde D, Croft H, Osoba D, Ottaway J, Gandara D. Randomized study of CODE versus alternating CAV/EP for extensive-stage small-cell lung cancer: an intergroup study of the NCIC Clinical Trials Group and the Southwest Oncology Group. Classic Papers & Current Comments 6(1): 169-77, 2001.
  • Myeloma Trialists' Collaborative Group. Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients. Br J Haematol 113: 1020-34, 2001.
  • Pater J, Browman G, Brouwers M, Nefsky M, Evans W, Cowan D. Funding new cancer drugs in Ontario: closing the loop in the practice guidelines development cycle. J Clin Oncol 19(14): 3392-6, 2001.
  • Pritchard KI, Paterson AHG, Fine S, Paul NA, Zee B, Shepherd LE, Abu-Zahra H, Ragaz J, Knowling M, Levine MN, Verma S, Perrault D, Walde PLD, Bramwell VHC, Poljicak M, Boyd N, Warr D, Norris BD, Bowman D, Armitage GR, Weizel H, Buckman RA. Randomized trial of cyclophosphamide, methotrexate, and fluorouracil chemotherapy added to tamoxifen as adjuvant therapy in postmenopausal women with node-positive estrogen and/or progesterone receptor-positive breast cancer: a report of the National Cancer Institute of Canada Clinical Trials Group. Classic Papers & Current Comments 5(4): 658-68, 2001.
  • Rusch VW, Giroux DJ, Kraut MJ, Crowley J, Hazuka M, Johnson D, Goldberg M, Detterbeck F, Shepherd F, Burkes R, Winton T, Deschamps C, Livingston R, Gandara D. Induction chemoradiation and surgical resection for non-small cell lung carcinomas of the superior sulcus: Initial results of Southwest Oncology Group trial 9416 (intergroup trial 0160). J Thorac Cardiovasc Surg 121: 472-83, 2001.
  • Sargent DJ, Goldberg RM, Jacobson SD, Macdonald JS, Labianca R, Haller D, Shepherd L, Seitz J, Francini G. A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med 345: 1091-7, 2001.
  • Seymour L. Epidermal growth factor receptor as a target: recent developments in the search for effective new anti-cancer agents. Current Drug Targets 2: 117-33, 2001.
  • Seymour L, Eisenhauer E. A review of dose limiting events in phase I trials: Antimetabolites show unpredictable relationships between dose and toxicity. Cancer Chemother Pharmacol 47(1): 2-10, 2001.
  • Shepherd FA, Dancey J, Arnold A, Neville A, Rusthoven J, Johnson RD, Fisher B, Eisenhauer E. Phase II study of Pemetrexed Disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma. A study of the NCIC Clinical Trials Group. Cancer 92(3): 595-600, 2001.
  • Tu D. Statistical procedures in therapeutic equivalence clinical trials with ordinal categorical clinical endpoints. Journal of Statistical Research 35(1): 65-77, 2001.
  • Tu D. Rao's score tests in survival analysis: examples and Bartlett type adjustments. Communications in Statistics-Theory & Methods 30: 1521-32, 2001.
  • Vermorken J. Intergroup collaboration in ovarian cancer: the Gynecologic Cancer Intergroup (GCIG). Int J Gynecol Cancer 11(Suppl. 1): 73-6, 2001.
  • Vermorken J, Eisenhauer E. Current developments in the treatment of cervical cancer. CME J Gynecol Oncol Chapter 18 Part 2: 52-60, 2001.
  • Bramwell V, Andrulis I, Bell R, Eisenhauer E, Fornasier V, Kandel R, O'Sullivan B, Temple W, Turcotte R, Wunder J. Canadian Sarcoma Group Workshop. Sarcomas: molecular markers to therapeutics, 26-27 February 2000, Toronto, Canada. Sarcoma 4: 67-73, 2000.
  • Dent SF, Klaassen D, Pater JL, Zee B, Whitehead M. Second primary malignancies following the treatment of early stage ovarian cancer: update of a study by the National Cancer Institute of Canada-Clinical Trials Group (NCIC-CTG). Ann Oncol 11(1): 65-8, 2000.
  • Eisenhauer E, Vermorken J. Principles and process of cancer drug development. CME J Gynecol Oncol Chapter 18 Part 1: 344-50, 2000.
  • Eisenhauer E. Phase I and II evaluation of novel anticancer agents: are response and toxicity the right endpoints? Onkolgie 23(suppl 3): 2-6, 2000.
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  • Flinn IW, Kopecky KJ, Foucar MK, Head D, Bennett JM, Hutchison R, Corbett WEN, Cassileth P, Habermann T, Golomb H, Rai K, Eisenhauer E, Appelbaum F, Cheson B, Grever M. Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin. Blood 96(9): 2981-6, 2000.
  • Geels P, Eisenhauer E, Bezjak A, Zee B, Day A. Palliative effect of chemotherapy: objective tumor response is associated with symptom improvement in patients with metastatic breast cancer. J Clin Oncol 18(12): 2395-405, 2000.
  • Gelmon KA, Latreille J, Tolcher A, Genier L, Fisher B, Forand D, D'Aloisio S, Vernillet L, Daigneault L, Lebecq A, Besenval M, Eisenhauer E. Phase I dose-finding study of a new taxane, RPR 109881A, administered as a one-hour intravenous infusion days 1 and 8 to patients with advanced solid tumours. J Clin Oncol 18(24): 4098-108, 2000.
  • Gertler SZ, Macdonald D, Goodyear M, Forsyth P, Stewart D, Belanger K, Perry J, Fulton D, Steward W, Wainman N, Seymour L. NCIC CTG phase II study of gemcitabine in patients with malignant glioma (IND.94). Ann Oncol 11(3): 315-8, 2000.
  • Hirte H, Goel R, Major P, Seymour L, Huan S, Stewart D, Yau J, Arnold A, Holohan S, Waterfield B, Bates S, Bennett K, Walsh W, Elias I. A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours. Ann Oncol 11(12): 1579-84, 2000.
  • Hoskins P, Eisenhauer E, Vergote I, Dubuc-Lissoir J, Fisher B, Grimshaw R, Oza A, Plante M, Stuart G, Vermorken J. Phase II feasibility study of sequential couplets of cisplatin/topotecan followed by paclitaxel/cisplatin as primary treatment for advanced epithelial ovarian cancer: a National Cancer Institute of Canada Clinical Trials Group study. J Clin Oncol 18(24): 4038-44, 2000.
  • Johnston JB, Eisenhauer E, Wainman N, Corbett WEN, Zaentz D, Daeninck PJ. Long-term outcome following treatment of hairy-cell leukemia with pentostatin (Nipent): a NCIC Clinical Trials Group study. Semin Oncol 27(2)(Suppl 5): 32-6, 2000.
  • Kirkbride P, Bezjak A, Pater J, Zee B, Palmer MJ, Wong R, Cross P, Gulavita S, Blood P, Sun A, Dundas G, Ganguly PK, Lim J, Chowdhury AD, Kumar SE, Dar AR. Dexamethasone for the prophylaxis of radiation-induced emesis - a NCIC Clinical Trials Group phase III study. J Clin Oncol 18(9): 1960-6, 2000.
  • Miller WH, Reyno L, Batist G, Loewen G, Cato J, Jaunakais D, Parker BA, Truglia J, Beare S, Matthews S, Dancey J, Eisenhauer E. A phase I study of 9-cis-retinoic acid and interferon alpha in patients with renal cell carcinoma: an NCIC Clinical Trials Group study. Ann Oncol 11: 1387-9, 2000.
  • Norris B, Pritchard KI, James K, Myles J, Bennett K, Marlin S, Skillings J, Findlay B, Vandenberg T, Goss P, Latreille J, Rudinskas L, Lofters W, Trudeau M, Osoba D, Rodgers A. A phase III comparative study of vinorelbine combined with doxorubicin versus doxorubicin alone in disseminated metastatic/recurrent breast cancer: a NCIC Clinical Trials Group study MA8. J Clin Oncol 18: 2385-94, 2000.
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  • Therasse P, Arbuck SG, Eisenhauer E, Wanders J, Kaplan RS, Rubinstein L, Verweij J, van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SG. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 92(3): 205-16, 2000.
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  • Tu D, Shalay K, Pater J. Adjustment of treatment effect for covariates in clinical trials: statistical and regulatory issues. Drug Information Journal 34(2): 511-23, 2000.
  • Vergote I, Rustin G, Eisenhauer E, Kristensen G, Pujade-Lauraine E, Parmar M, Friedlander M, Jakobsen A, Vermorken J. New guidelines to evaluate the response to treatment in solid tumors (ovarian cancer). J Natl Cancer Inst 92(18): 1534-5, 2000.
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  • Berek J, Bertelsen K, du Bois A, Brady F, Carmichael J, Eisenhauer E, Gore M, Grenman S, Hamilton T, Hansen SW, Harper P, Horvath G, Kaye S, Lück H-J, Lund B, McGuire WP, Neijt J, Ozols R, Parmar M, Piccart-Gebhart MJ, van Rijswijk R, Rosenberg P, Rustin G, Sessa C, Thigpen T, Trope C, Tuxen M, Vergote I, Vermorken J, Willemse PHB. Advanced epithelial ovarian cancer: 1998 consensus statements. Ann Oncol 10: 87-92, 1999.
  • Catzavelos C, Tsao MS, DeBoer G, Bhattacharya N, Shepherd FA, Slingerland JM. Reduced expression of the cell cycle inhibitor p27Kip1 in non-small cell lung carcinoma: a prognostic factor independent of Ras. Cancer Research 59(3): 684-8, 1999.
  • Cripps C, Burnell M, Jolivet J, Batist G, Lofters W, Dancey J, Iglesias J, Fisher B, Eisenhauer EA. Phase II study of first-line LY231514 (multi-targeted antifolate) in patients with locally advanced or metastatic colorectal cancer: An NCIC Clinical Trials Group study. Ann Oncol 10: 1175-9, 1999.
  • Crump M, Lipton J, Hedley D, Sutton D, Shepherd F, Minden M, Stewart K, Beare S, Eisenhauer E. Phase I trial of sequential topotecan followed by etoposide in adults with myeloid leukemia: a NCIC Clinical Trials Group study. Leukemia 13: 343-7, 1999.
  • Eisenhauer E, Gore M, Neijt J. Ovarian Cancer: Should we be managing patients with good and bad prognostic factors in the same manner? Ann Oncol 10(Suppl 1): 9-15, 1999.
  • Erlichman C, Marsoni S, Seitz J, Skillings J, Shepherd L, Zee B, Milan C, Bedenne L, Giovanni M, LeTruet Y, Torri V, Tardio B, Zaniboni A, Pancera G, Martignoni G, O'Connell M, Kahn M, Francini G. Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. By the International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) Investigators. J Clin Oncol 17(5): 1356-63, 1999.
  • Gelmon K, Eisenhauer E, Bryce C, Tolcher A, Mayer L, Tomlinson E, Zee B, Blackstein M, Tomiak E, Yau J, Batist G, Fisher B, Iglesias J. A randomized study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer. J Clin Oncol 17: 3038-47, 1999.
  • Gelmon K, Eisenhauer E, Harris A, Ratain M, Workman M. Anticancer agents targeting signaling molecules and cancer cell environment: challenges for drug development? J Natl Cancer Inst 91(15): 1281-7, 1999.
  • Hoskins PJ, Eisenhauer EA, van Glabbeke M, Vermorken JB, Tu D, James K. Predicting outcome after initial relapse of epithelial ovarian cancer: can we identify patients who will not benefit from further therapy? CME J Gynecol Oncol Chapter 13 Part 1: 64-8, 1999.
  • Hospers GAP, Eisenhauer E, de Vries EGE. The sulfhydryl containing compounds WR-2721 and glutathione as radio- and chemoprotective agents. A review, indications for use and prospects. Br J Cancer 80(5/6): 629-38, 1999.
  • International collaboration of trialists. Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: a randomised controlled trial. Lancet 354: 533-40, 1999.
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  • Kaye S, Eisenhauer E, Hamilton T. New non-cytotoxic approaches to ovarian cancer. Ann Oncol 10(Suppl 1): 65-8, 1999.
  • Khoo K, Brandes L, Reyno L, Arnold A, Dent S, Vandenberg T, Lebwohl D, Fisher B, Eisenhauer E. Phase II trial of N,N-diethyl-2[4-(phenylmethyl)phenoxy]ethanamine HCI (DPPE) and doxorubicin chemotherapy in metastatic breast cancer. A NCIC Clinical Trials Group study. J Clin Oncol 17(11): 3431-7, 1999.
  • Kirkbride P, Gelmon K, Eisenhauer E. Paclitaxel (Taxol) and concurrent radiotherapy in locally advanced non-small cell lung cancer - the Canadian experience. Semin Radiat Oncol 9 (2 Suppl 1): 102-7, 1999.
  • MacNeil M, Eisenhauer E. High dose chemotherapy: Is it standard management for any common solid tumor? Ann Oncol 10: 1145-61, 1999.
  • Michael M, Babic B, Khokha R, Tsao MS, Ho J, Pintilie M, Leco K, Chamberlain D, Shepherd FA. Expression and prognostic significance of metalloproteinases and their tissue inhibitors in patients with small-cell lung cancer. J Clin Oncol 17(6): 1802-8, 1999.
  • Moore M, Winquist E, Murray N, Tannock I, Huan S, Bennett K, Walsh W, Seymour L. Gemcitabine plus cisplatin, an active regimen in advanced urothelial cancer. A phase II trial of the NCIC Clinical Trials Group. J Clin Oncol 17(9): 2876-81, 1999.
  • Murray N, Livingston R, Shepherd F, James K, Zee B, Langleben A, Kraut M, Bearden J, Goodwin J, Grafton C, Turrisi A, Walde D, Croft H, Osoba D, Ottaway J, Gandara D. Randomized study of CODE versus alternating CAV/EP for extensive-stage small-cell lung cancer: an intergroup study of the NCIC Clinical Trials Group and the Southwest Oncology Group. J Clin Oncol 17(8): 2300-8, 1999.
  • Osoba D. Interpreting the meaningfulness of changes in health-related quality of life scores; lessons from adults. Int J Cancer 83(suppl): 132-7, 1999.
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  • Piccart M, Stuart G, Cassidy J, Bertelsen K, Parmar M, Eisenhauer E, Kaye S, Trope C, Swenerton K, Harper P, Vermorken J. Intergroup collaboration in ovarian cancer: a giant step forward. Ann Oncol 10(Suppl 1): 83-6, 1999.
  • Quon H, Shepherd F, Payne D, Coy P, Murray N, Feld R, Pater J, Sadura A, Zee B. The influence of age on the delivery, tolerance and efficacy of thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer. Int J Rad Oncol Biol Phys 43(1): 39-45, 1999.
  • Rusthoven J, Eisenhauer E, Butts C, Gregg R, Dancey J, Fisher B, Iglesias J. Multi-targeted antifolate LY231514 as a first-line chemotherapy for patients with advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 17: 1194-9, 1999.
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  • Zee B, Melnychuck D, Dancey J, Eisenhauer E. Multinomial phase II cancer trials incorporating response and early progression. J Biopharmaceutical Statistics 9(2): 351-63, 1999.
  • Advanced Ovarian Cancer Trialists' Group. Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Br J Cancer 78(11): 1479-87, 1998.
  • Bramwell V, Blackstein M, Belanger K, Verma S, Beare S, Eisenhauer E. A phase II study of docetaxel in chemotherapy-naive patients with recurrent or metastatic adult soft tissue sarcoma. Sarcoma 2: 29-33, 1998.
  • Crump M, Gluck S, Pritchard K, Shepherd L, Pater J. High-dose chemotherapy with autologous hematopoietic stem-cell support for breast cancer in North America (letter to the editor). J Clin Oncol 16(2): 800-1, 1998.
  • Eisenhauer E. Cytoprotection. European Society for Medical Oncology Educational Book, 109-113, 1998.
  • Eisenhauer E. Phase I and II trials of novel anticancer agents: endpoints, efficacy and existentialism. The Michael Clavel Lecture. Ann Oncol 9(10): 1047-52, 1998.
  • Eisenhauer E, Vermorken J. The Taxoids. Comparative clinical pharmacology and therapeutic potential. Drugs 55(1): 5-30, 1998.
  • Eisenhauer EA, Ten Bokkel-Huinink WW, Swenerton KD, Gianni L, Myles J, van der Burg MEL, Kerr I, Vermorken JB, Buser K, Colombo N, Bacon M, Santabárbara P, Onetto N, Winograd B, Canetta R. European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: high-dose versus low-dose and long versus short infusion. Classic Papers & Current Comments 3: 171-84, 1998.
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  • Hoskins P, Eisenhauer E, Beare S, Roy M, Drouin P, Stuart G, Bryson P, Grimshaw R, Capstick V, Zee B. Randomized phase II study of two schedules of topotecan in previously treated patients with ovarian cancer: a NCIC Clinical Trials Group Study. J Clin Oncol 16(6): 2233-7, 1998.
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  • Levine M, Pritchard K, Bramwell V, Shepherd L. Adjuvant chemotherapy with CEF versus CMF for node-positive breast cancer (in reply letter to the editor). J Clin Oncol 16(12): 3917, 1998.
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  • Maroun JA, Stewart D, Verma S, Eisenhauer E. Phase I clinical study of didemnin B A National Cancer Institute of Canada Clinical Trials Group study. Invest New Drugs 16: 51-6, 1998.
  • Meta Analysis Group in Cancer. Toxicity of fluorouracil in patients with advanced colorectal cancer; effect of administration schedule and prognostic factors. J Clin Oncol 16(11): 3537-41, 1998.
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  • Shepherd FA, Eisenhauer E. Ifosfamide and paclitaxel combinations for the treatment of advanced non-small cell lung cancer. Semin Oncol 25(1 Suppl 2): 2-7, 1998.
  • Shepherd FA, Johnston M, Payne D, Burkes R, Deslauriers J, Cormier Y, Diaz de Bedoya L, Ottaway J, James K, Zee B. Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small cell lung cancer:a NCIC Clinical Trials Group study. Br J Cancer 78(5): 683-5, 1998.
  • Shustik C. Interferon in the treatment of multiple myeloma. Cancer Control 5(3): 226-34, 1998.
  • Siu LL, Oza AM, Eisenhauer EA, Firby PS, Thiessen JJ, Michael M, Wainman N, Manzo J, Feld R, Goldberg RA, Moore MJ. Phase I and pharmacological study of 9-aminocamptothecin colloidal dispersion formulation given as a 24-hour continuous infusion weekly times four every 5 weeks. J Clin Oncol 16: 1122-30, 1998.
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  • Zee B, Cole B, Li T, Browman G, James K, Johnston D, Sugano D, Pater J. Quality-adjusted time without symptoms or toxicity analysis of interferon maintenance in multiple myeloma. J Clin Oncol 16(8): 2834-9, 1998.
  • Zee B. Growth curve model analysis for quality of life data. Statistics in Medicine 17: 757-66, 1998.
  • Bacon M. The evolving role of nurses in clinical trials. Can Onc Nursing J 7(2): 79-80, 1997.
  • Connors JM, Klimo P, Adams G, Burns BF, Cooper I, Meyer RM, O'Reilly SE, Pater J, Quirt I, Sadura A, Shustik C, Skillings J, Sutcliffe S, Verma S, Yoshida S, Zee B. Treatment of advanced Hodgkin's disease with chemotherapy - comparison of MOPP/ABV hybrid regimen with alternating courses of MOPP and ABVD: a report from the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 15: 1638-45, 1997.
  • Crump M, Sawka CA, DeBoer G, Buchanan RB, Ingle JN, Forbes J, Meakin JW, Shelley W, Pritchard KI. An individual patient-based meta-analysis of tamoxifen versus ovarian ablation as first line endocrine therapy for premenopausal women with metastatic breast cancer. Breast Cancer Res Treat 44: 201-10, 1997.
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  • Einhorn LH. (Guest Editor). Highlights of lung cancer research. Classic Papers & Current Comments 2(1): 21-30, 1997.
  • Eisenhauer E, Vermorken J. New cytotoxic drugs. South Am J of Cancer 1: 17-32, 1997.
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  • Goss P, Fine S, Gelmon K, Rudinskas L, Ottaway J, Myles J, James K, Paul K, Rodgers A, Pritchard K. Phase I studies of fluorouracil, doxorubicin and vinorelbine without (FAN) and with (SUPERFAN) folinic acid in patients with advanced breast cancer. Cancer Chemother Pharmacol 41(1): 53-60, 1997.
  • Kirkbride P, Gelmon K, Eisenhauer E, Fisher B, Dulude H. A phase I/II study of paclitaxel (Taxol) and concurrent radiotherapy in advanced non small cell lung cancer. Int J Rad Oncol Biol Phys 39(5): 1107-11, 1997.
  • Lofters W, Pater J, Zee B, Dempsey E, Walde D, Moquin J, Wilson K, Hoskins P, Guevin R, Verma S, Navari R, Krook J, Hainsworth J, Palmer M, Chin C. Phase III double-blind comparison of dolasetron mesylate and ondansetron and an evaluation of the additive role of dexamethasone in the prevention of acute and delayed nausea and vomiting due to moderately emetogenic chemotherapy. J Clin Oncol 15(8): 2966-73, 1997.
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  • Osoba D, Aaronson N, Zee B, teVelde A, Sprangers M. Modification of the EORTC QLQ-C30 (version 2.0) based on content validity and reliability testing in large samples of patients with cancer. Quality of Life Research 6: 103-8, 1997.
  • Pater JL, Zee B, Palmer M, Johnston D, Osoba D. Fatigue in patients with cancer: results with NCIC Clinical Trials Group Studies employing the EORTC QLQ-C30. Supportive Care in Cancer 5: 410-3, 1997.
  • Pater JL, Lofters WS, Zee B, Dempsey E, Walde D, Moquin J-P, Wilson K, Hoskins P, Guevin RM, Verma S, Navari R, Krook JE, Hainsworth J, Palmer M, Chin C. The role of 5-HT3 antagonists ondansetron and dolasetron in the control of delayed onset nausea and vomiting in patients receiving moderately emetogenic chemotherapy. Ann Oncol 8: 181-5, 1997.
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  • Sawka CA, Pritchard KI, Shelley W, DeBoer G, Paterson AHG, Meakin JW, Sutherland DJA. A randomized crossover trial of tamoxifen versus ovarian ablation for metastatic breast cancer in premenopausal women: A report of the NCIC Clinical Trials Group (NCIC CTG) trial MA.1. Breast Cancer Res Treat 44(3): 211-5, 1997.
  • Souhami RL, Craft AW, Van der Eijken JW, Nooij M, Spooner D, Bramwell V, Wierzbicki R, Malcolm AJ, Kirkpatrick A, Uscinska BM, van Glabbeke M, Machin D. Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup. Lancet 350(9082): 911-7, 1997.
  • Tallman M, Andersen J, Schiffer C, Appelbaum F, Feusner J, Ogden A, Shepherd L, Willman C, Bloomfield C, Rowe J, Wiernik P. All-trans-retinoic acid in acute promyelocytic leukemia. N Engl J Med 337: 1021-8, 1997.
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  • Bow EJ, Mandell LA, Louie TJ, Feld R, Palmer M, Zee B, Pater J. Quinolone-based antibacterial chemoprophylaxis in neutropenic patients: effect of augmented gram-positive activity on infectious morbidity. Ann Intern Med 125: 183-90, 1996.
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  • Dent S, Eisenhauer E. Phase I trial design: are new methodologies being put into practice? Ann Oncol 7: 561-6, 1996.
  • Eisenhauer E, Vermorken J. New drugs in gynecologic oncology. Curr Opin Oncol 8: 408-14, 1996.
  • Eisenhauer E. The role of paclitaxel in ovarian cancer treatment. Oncology and Hematology 4: 7-9, 1996.
  • Forsyth P, Cairncross G, Stewart D, Goodyear M, Wainman N, Eisenhauer E. Phase II trial of docetaxel in patients with recurrent malignant glioma: a study of the National Cancer Institute of Canada Clinical Trials Group. Invest New Drugs 14(2): 203-6, 1996.
  • Latreille J, Cormier Y, Martins H, Goss G, Fisher B, Eisenhauer EA. Phase II study of docetaxel (taxotere) in patients with previously untreated extensive small cell lung cancer. Invest New Drugs 13: 343-5, 1996.
  • Macdonald D, Cairncross G, Stewart D, Forsyth P, Sawka C, Wainman N, Eisenhauer E. Phase II study of topotecan in patients with recurrent malignant glioma. Ann Oncol 7: 205-7, 1996.
  • Nicklee T, Crump M, Hedley D. Effects of topoisomerase I inhibition on the expression of topoisomerase II alpha measured with fluorescence image cytometry. Cytometry 25(3): 205-10, 1996.
  • O'Connell MJ, Kahn MJ, Erlichman C, Goldberg RM, Shepherd LE. Optimal duration of fluorouracil plus levamisole colon cancer surgical adjuvant therapy (letter to the editor). J Clin Oncol 14: 2887, 1996.
  • Osoba D, Dancey J, Zee B, Myles J, Pater J. Health-related quality-of-life studies of the National Cancer Institute of Canada Clinical Trials Group. J Natl Cancer Inst Monogr No.20: 107-11, 1996.
  • Osoba D, Zee B, Warr D, Kaizer L, Latreille J, Pater J. Quality of life studies in chemotherapy-induced emesis. Oncology 53(suppl 1): 92-5, 1996.
  • Perrault D, Eisenhauer EA, Pritchard KI, Panasci L, Norris B, Vandenberg T, Fisher B. Phase II study of the progesterone antagonist mifepristone in patients with untreated metastatic breast carcinoma: a National Cancer Institute of Canada Clinical Trials Group study. J Clin Oncol 14: 2709-12, 1996.
  • Pritchard KI, Paterson AHG, Paul NA, Zee B, Fine S, Pater J. Increased thromboembolic complications with concurrent tamoxifen and chemotherapy in a randomized trial of adjuvant therapy for women with breast cancer. J Clin Oncol 14: 2731-7, 1996.
  • Rusthoven JJ, Quirt IC, Iscoe NA, McCulloch PB, James KW, Lohmann RC, Jensen J, Burdette-Radoux S, Bodurtha AJ, Silver HKB, Verma S, Armitage GR, Zee B, Bennett K. Randomized double-blind placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma. J Clin Oncol 14: 2083-90, 1996.
  • Shepherd FA, Latreille J, Paul K, Eisenhauer E. Phase I dose-escalation trial of paclitaxel and ifosfamide in patients with advanced non-small cell lung cancer. Semin Oncol 23(6) Suppl 16: 84-90, 1996.
  • Shepherd FA, Latreille J, Crump M, Stewart D, Tomiak E, Eisenhauer E, Fisher B. Phase I study of paclitaxel (Taxol) and ifosfamide in previously untreated patients with advanced non-small-cell lung cancer. Ann Oncol 7: 311-3, 1996.
  • Shepherd FA, Latreille J, Crump M. Phase I study of paclitaxel (TaxolR) and ifosfamide in previously untreated patients with advanced non-small cell lung cancer. A study of the NCIC Clinical Trials Group. Lung Cancer 16(1): 122, 1996.
  • Siu L, Shepherd F, Murray N, Feld R, Pater J, Zee B. The influence of age on the treatment of limited-stage small-cell lung cancer. J Clin Oncol 14(3): 821-8, 1996.
  • Swenerton K, Hoskins P, Stuart G, Batist G, Pike J, Onetto N, Fisher B, Eisenhauer E. A phase I study of biweekly paclitaxel/cisplatin as initial therapy for advanced ovarian cancer. Ann Oncol 7: 1077-9, 1996.
  • Trudeau ME, Eisenhauer EA, Higgins BP, Letendre F, Lofters WS, Norris BD, Vandenberg TA, Delorme F, Muldal AM. Docetaxel in patients with metastatic breast cancer. a phase II study of the National Cancer Institute of Canada-Clinical Trials Group. J Clin Oncol 14: 422-8, 1996.
  • Tu D, Gross AJ. A Bartlett type correction for the subject-years method in comparing survival data to a standard population. Statistics & Probability Letters 29: 149-57, 1996.
  • Viallet J, Stewart D, Shepherd F, Ayoub J, Cormier Y, DiPietro N, Steward W. Tallimustine is inactive in patients with previously treated small cell lung cancer. A phase II trial of the NCIC Clinical Trials Group. Lung Cancer 15: 367-73, 1996.
  • Belch A, Eisenhauer E, Muldal A, Browman G, Klasa R, Osterwalder B. Phase II study of subcutaneous rHu interleukin-2 and rHu-interferon alpha-2a in previously treated patients with multiple myeloma. Ann Oncol 6: 721-3, 1995.
  • Bramwell V, Eisenhauer E, Blackstein M, Boos G, Knowling M, Jolivet J, Bogues W. Phase II study of topotecan (NSC 609 699) in patients with recurrent or metastatic soft tissue sarcoma. Ann Oncol 6: 847-9, 1995.
  • Browman G, Bergsagel D, Sicheri D, O'Reilly S, Wilson K, Rubin S, Belch A, Shustik C, Barr R, Walker I, James K, Zee B, Johnston D. Randomized trial of interferon maintenance in multiple myeloma: a study of the NCIC Clinical Trials Group. J Clin Oncol 13(9): 2354-60, 1995.
  • Cairncross G, Eisenhauer E. Response and Control: lessons from oligodendroglioma (letter to the editor). J Clin Oncol 13: 2475, 1995.
  • Dancey J, Steward W, William P. The role of vindesine in oncology-recommendations after 10 years' experience. Anti Cancer Drugs 6: 625-36, 1995.
  • Eisenhauer E, Trudeau M. An overview of phase II studies of docetaxel in patients with metastatic breast cancer. Eur J Can 31A(Suppl.4): 11, 1995.
  • Eisenhauer E. Docetaxel: current status and future prospects. J Clin Oncol 13(12): 2865-8, 1995.
  • Ghersi D, Stewart LA, Parmar MKB, Coppin C, Martinez-Pineiro J, Raghavan D, Wallace M. Does neoadjuvant cisplatin-based chemotherapy improve the survival of patients with locally advanced bladder cancer: a meta-analysis of individual patient data from randomized clinical trials. Br J Urology 75: 206-13, 1995.
  • Goss G, Muldal A, Lohmann R, Taylor M, Lopez P, Armitage G, Steward W. Didemnin B in favourable histology non-Hodgkin's lymphoma. A phase II study of the NCIC Clinical Trials Group. Invest New Drugs 13: 257-60, 1995.
  • Grever M, Kopecky K, Foucar MK, Bennett JM, Habermann T, Rai K, Eisenhauer E, Cheson BD. Reply to the letter Optimal Treatment for untreated patients with hairy cell leukemia? J Clin Oncol 13: 2677-9, 1995.
  • Grever M, Kopecky K, Foucar MK, Head D, Bennett JM, Hutchison RE, Corbett WEN, Cassileth PA, Habermann T, Golomb H, Rai K, Eisenhauer E, Appelbaum F, Cheson BD. Randomized comparison of pentostatin versus interferon alfa-2a in previously untreated patients with hairy cell leukemia: an intergroup study. J Clin Oncol 13: 974-82, 1995.
  • Labianca R, Marsoni S, Pancera G, Torri V, Zaniboni A, Erlichman C, Pater J, Shepherd L, Zee B, Seitz JF, Milan C, Pignon JP. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. (International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) Investigators). Lancet 345: 939-44, 1995.
  • Latreille J, Stewart D, Laberge F, Hoskins P, Rusthoven J, McMurtrie E, Warr D, Yelle L, Walde D, Shepherd F, Dhaliwal H, Findlay B, Mee D, Pater J, Zee B, Johnston D. Dexamethasone improves the efficacy of granisetron in the first 24 hours following high dose cisplatin chemotherapy. Supportive Care in Cancer 3(5): 307-13, 1995.
  • Osoba D, Till J, Pater J, Young J. Health-related quality of life: measurement and clinical application (a workshop report). Can J Oncol 5(1): 338-43, 1995.
  • Palmer M, McBride J. Working towards a national oncology pharmacists network. Hospital Pharmacy Practice 3(3): 24-5, 1995.
  • Pater J, Zee B, Myles J, Pignon J, Milan C, Sahmoud T, Torri V, Marsoni S. A proposal for a new approach to intergroup cancer trials. Eur J Can 31A(12): 1921-3, 1995.
  • Pater J, Warr D. Roila original article (dexamethasone, granisetron, or both for the prevention of nausea and vomiting during chemotherapy for cancer (letter to editor). N Engl J Med 332: 1653, 1995.
  • Payne D, Coy P, Hodson I, Murray N, Pater J, Wilson K. Coy et al. original article (Patterns of failure following loco-regional radiotherapy in the treatment of limited stage small cell lung cancer) (letter to editor). Int J Rad Oncol Biol Phys 31(1): 207, 1995.
  • Pearcey R, Stuart G, MacLean G, Nation J, Arthur K, Lukka H, Jeffrey J, James K, Brundage M. Phase II study to evaluate the toxicity and efficacy of concurrent cisplatin and radiation therapy in the treatment of patients with locally advanced squamous cell carcinoma of the cervix. Gynecol Oncol 58: 34-41, 1995.
  • Piccart M, Raymond E, Aapro M, Eisenhauer E, Cvitkovic E. Cytotoxic agents with activity in breast cancer patients previously exposed to anthracyclines: current status and future prospects. Eur J Can 31A(Suppl 7): 1-10, 1995.
  • Raby B, Pater J, Mackillop W. Does Knowledge Guide Practice? Another look at the management of non-small-cell lung cancer. J Clin Oncol 13(8): 1904-11, 1995.
  • Arnold A, Ayoub J, Douglas L, Hoogendoorn P, Skingley L, Gelmon K, Hirsh V, Eisenhauer E. Phase II trial of 13-cis-retinoic acid plus interferon alpha in non-small-cell lung cancer. J Natl Cancer Inst 86(4): 306-9, 1994.
  • Bacon M. The Nursing implications of an international clinical trial of taxol. Gynecol Oncol Nursing 4(1): 21-4, 1994.
  • Bacon M. Cancer clinical trials - nursing opportunities. Gynecol Oncol Nursing 4(4): 19-21, 1994.
  • Cairncross G, Macdonald D, Ludwin S, Lee D, Cascino T, Buckner J, Fulton D, Dropcho E, Stewart D, Schold C, Wainman N, Eisenhauer E. Chemotherapy for anaplastic oligodendroglioma. J Clin Oncol 12(10): 2013-21, 1994.
  • Cormier Y, Eisenhauer E, Muldal A, Gregg R, Ayoub J, Goss G, Stewart D, Tarasoff P, Wong D. Gemcitabine is an active new agent in previously untreated extensive small cell lung cancer. Ann Oncol 5: 283-5, 1994.
  • Coy P, Hodson I, Murray N, Pater J, Payne D, Arnold A, Kostashuk E, Dixon P, Evans W, Zee B, Sadura A, Ayoub J, Levitt M, Wierzbicki R, Feld R, Maroun J, Wilson K. Patterns of failure following locoregional radiotherapy in the treatment of limited stage small cell lung cancer. Int J Rad Oncol Biol Phys 28: 355-62, 1994.
  • Eisenhauer E, Lippman S, Kavanagh J, Parades-Espinoza M, Arnold A, Hong W, Massimini G, Schleuninger U, Bollag W, Holdener E, Krakoff I. Combination 13-cis-retinoic acid and interferon alpha-2a in the therapy of solid tumors. Leukemia 8: 1622-5, 1994.
  • Eisenhauer E, Ten Bokkel-Huinink W, Swenerton K, Gianni L, Myles J, van der Burg M, Kerr I, Vermorken J, Buser K, Colombo N, Bacon M, Santabarbara P, Onetto N, Winograd B, Canetta R. European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: high-dose versus low-dose and long versus short infusion. J Clin Oncol 12(12): 2654-66, 1994.
  • Goss G, Letendre F, Stewart D, Shepherd F, Schacter L, Hoogendoorn P, Eisenhauer E. Phase II study of elsamitrucin in non-small cell lung cancer. Invest New Drugs 12: 315-7, 1994.
  • Kaizer L, Warr D, Hoskins P, Latreille J, Lofters W, Yau J, Palmer M, Zee B, Levy M, Pater J. The effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in acute and delayed nausea and emesis in patients receiving moderately emetogenic chemotherapy: a phase III trial by the NCIC Clinical Trials Group. J Clin Oncol 12(5): 1050-7, 1994.
  • Knowling M, Bramwell V, Eisenhauer E, Boos G, Bodurtha A, Quirt I. Phase II trial of 10-EDAM in advanced soft tissue sarcoma. A study of the Canadian Sarcoma Group and the NCIC Clinical Trials Group. Ann Oncol 5(8): 766-8, 1994.
  • Mertens W, Eisenhauer E, Jolivet J, Ernst S, Moore M, Muldal A. Docetaxel in advanced renal carcinoma: a phase II trial of the NCIC Clinical Trials Group. Ann Oncol 5(4): 185-7, 1994.
  • Murray N, Coppin C, Coldman A, Pater J, Rapp E. Drug delivery analysis of the Canadian multicenter trial in non-small-cell lung cancer. J Clin Oncol 12(11): 2333-9, 1994.
  • Osoba D, Zee B, Pater J, Warr D, Kaizer L, Latreille J. Psychometric properties and responsiveness of the EORTC Quality of Life Questionnaire (QLQ-C30) in patients with breast, ovarian and lung cancer. Quality of Life Research 3: 353-64, 1994.
  • Pater J, Mackillop W, Brundage M, Goodwin P, Osoba D, Llewellyn-Thomas H. Outcome measurements in oncology (symposium). Ann R Coll Phy Surg Can 27(3): 174-8, 1994.
  • Pater J. Timing the collaborative analysis of three trials comparing 5-FU plus folinic acid (FUFA) to surgery alone in the management of resected colorectal cancer: A NCIC Clinical Trials Group perspective. Statistics in Medicine 13: 1337-40, 1994.
  • Pater J, Slamet L, Zee B, Osoba D, Warr D, Rusthoven J. Inconsistency of prognostic factors for post-chemotherapy nausea and vomiting. Supportive Care in Cancer 2(3): 161-6, 1994.
  • Pritchard KI. Clinical cooperative trials of the NCIC Clinical Trials Group Breast Cancer Site Group. Cancer 74(Suppl 3): 1150-5, 1994.
  • Shepherd L, Ottaway J, Myles J, Levine M. Therapy-related leukemia associated with high-dose 4-epi-doxorubicin and cyclophosphamide used as adjuvant chemotherapy for breast cancer (letter to the editor). J Clin Oncol 12(11): 2514-5, 1994.
  • Till J, Osoba D, Pater J, Young J. Research on health-related quality of life: dissemination into practical applications. Quality of Life Research 3: 279-83, 1994.
  • Allen D, Baak J, Belpomme D, Berek J, Bertelsen K, Ten Bokkel-Huinink W, van der Burg M, Calvert A, Conte P, Dauplat J, Eisenhauer E, Favalli G, Hacker N, Hamilton T, Hansen H, Hansen M, van Houwelingen H, Kaye S, Levin L, Lund B, Neijt J, Ozols R, Piccart M, Rustin G, Sessa C, Soutter W, Thigpen T, Trope C, Vermorken J, de Vries E. Advanced epithelial ovarian cancer: 1993 consensus statements. Ann Oncol 4(Suppl.4): 83-8, 1993.
  • Balch C, Urist M, Karakousis C, Smith T, Temple W, Drzewiecki K, Jewell W, Bartolucci A, Mihm M, Jr., Barnhill R, Wanebo H. Efficacy of 2-cm surgical margins for intermediate-thickness melanomas (1 to 4 mm). Results of a multi-institutional randomized surgical trial. Ann Surg 218(3): 262-9, 1993.
  • Bélanger K, Jolivet J, Maroun J, Stewart D, Grillo-Lopez A, Whitfield L, Wainman N, Eisenhauer E. Phase I pharmacokinetic study of DUP-937. Invest New Drugs 11(4): 301-8, 1993.
  • Brundage M, Pater J, Zee B. Assessing the reliability of two toxicity scales: implications for interpreting toxicity data. J Natl Cancer Inst 85(14): 1138-48, 1993.
  • Eisenhauer E. Taxol in advanced non-small cell lung cancer: plus ca change? J Natl Cancer Inst 85(5): 346-7, 1993.
  • Feld R, Pater J, Goodwin P, Grossman R, Coy P, Murray N. The restaging of responding patients with limited small cell lung cancer -- is it really useful? Chest 103(4): 1010-6, 1993.
  • Gregg R, Kaizer L, Fine S, Gelmon K, Wielgosz G, Eisenhauer E. A phase II trial of DuP 937 (Teloxantrone) in non-small cell lung cancer. A study of the NCIC Clinical Trials Group. Ann Oncol 4(8): 693-4, 1993.
  • Hansen H, Eisenhauer E, Hansen M, Neijt J, Piccart M, Sessa C, Thigpen T. New cytostatic drugs in ovarian cancer. Ann Oncol 4(Suppl.4): 63-70, 1993.
  • Johnston D. Lessons learned from coordinating a pivotal clinical trial. J Clin Res and Drug Development 7: 31-9, 1993.
  • Levitt M, Warr D, Yelle L, Rayner H, Lofters W, Perrault D, Wilson K, Latreille J, Potvin M, Warner E, Pritchard K, Palmer M, Zee B, Pater J. Ondansetron compared with dexamethasone and metoclopramide as antiemetics in the chemotherapy of breast cancer with cyclophosphamide, methotrexate, and fluorouracil. N Engl J Med 328(15): 1081-4, 1993.
  • Maroun JA, Skillings J, MacCormick R, Potvin M, Wielgosz G, Davidson JR, Eisenhauer E. Phase II study on DuP 937 (Teloxantrone) in colorectal carcinoma: A Canadian National Cancer Institute Clinical Trial Group study. Invest New Drugs 11: 235-7, 1993.
  • Mertens W, Eisenhauer E, Moore M, Venner P, Stewart D, Muldal A, Wong D. Gemcitabine in advanced renal cell carcinoma. A phase II study of the NCIC Clinical Trials Group. Ann Oncol 4: 331-2, 1993.
  • Meyer RM, Quirt IC, Skillings JR, Cripps MC, Bramwell V, Weinerman BH, Gospodarowicz MK, Burns BF, Sargeant A-M, Shepherd LE, Zee B, Hryniuk WM. Escalated as compared with standard doses of doxorubicin in BACOP therapy for patients with non-Hodgkin's lymphoma. N Engl J Med 329: 1770-6, 1993.
  • Murray N, Coy P, Pater J, Hodson I, Arnold A, Zee B, Payne D, Kostashuk E, Evans W, Dixon P, Sadura A, Feld R, Levitt M, Wierzbicki R, Ayoub J, Maroun J, Wilson K. Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. J Clin Oncol 11(2): 336-44, 1993.
  • Niezgoda H, Pater J. A validation study of the domains of the core EORTC quality of life questionnaire. Quality of Life Research 2: 319-25, 1993.
  • Osoba D, Pater J. Assessing quality of life in clinical trials (letter to the editor). Ann Oncol 4(6): 520, 1993.
  • Pater JL. Polychemotherapy in advanced non-small cell lung cancer.(letter to the editor). Lancet 342: 741-2, 1993.
  • Pater J, Bacon M. Guest Editorial: Clinical Trials Group of NCIC. Can Onc Nursing J 3(3): 114, 1993.
  • Pater J. The use of data monitoring committees in Canadian trial groups. Statistics in Medicine 12: 505-8, 1993.
  • Pater J. Implications for clinical research - cancer treatment under pressure. Can J Oncol 3(3): 44-5, 1993.
  • Peereboom DM, Donehower RC, Eisenhauer E, McGuire WMP, Onetto N, Hubbard JL, Piccart M, Gianni L, Rowinsky E. Successful re-treatment with taxol after major hypersensitivity reactions. J Clin Oncol 11(5): 885-90, 1993.
  • Reyno L, Egorin M, Canetta R, Jodrell D, Swenerton K, Pater J, Burroughs J, Novak M, Sridhara R. Impact of cyclophosphamide on relationships between carboplatin exposure and response or toxicity when used in the treatment of advanced ovarian cancer. J Clin Oncol 11(6): 1156-64, 1993.
  • Rowinsky E, Eisenhauer E, Chaudhry V, Arbuck SG, Donehower RC. Clinical toxicities encountered with paclitaxel (Taxol). Semin Oncol 20(4) Suppl 3: 1-15, 1993.
  • Rusthoven J, Eisenhauer E, Mazurka J, Hirte H, O'Connell G, Muldal A, Lu H, Onetto N, Swenerton K, Jeffrey J. Phase I clinical trial of recombinant human interleukin-3 combined with carboplatin in the treatment of patients with recurrent ovarian carcinoma. J Natl Cancer Inst 85(10): 823-5, 1993.
  • Shore T, Eisenhauer E, Quirt I, Belanger K, Lohmann R, Silver H, Wielgosz G. A phase II study of DuP-937 (Teloxantrone) in metastatic malignant melanoma: a study of the NCIC Clinical Trials Group. Ann Oncol 4(8): 695-6, 1993.
  • Souquet PJ, Chauvin F, Boissel JP, Cellerino R, Cormier Y, Ganz PA, Kaasa S, Pater JL, Quoix E, Rapp E, Tumarello D, Williams J, Woods BL, Bernard JP. Polychemotherapy in advanced non-small cell lung cancer: a meta-analysis. Lancet 342: 19-21, 1993.
  • Stewart D, Eisenhauer E, Macdonald D, Cairncross G, Langleben A. Phase II study of tiazofurin in gliomas in adults. J Neuro Oncol 15: 175-9, 1993.
  • Thigpen T, Bertelsen K, Eisenhauer E, Hacker N, Lund B, Sessa C. Long-term follow-up of patients with advanced ovarian carcinoma treated with chemotherapy. Ann Oncol 4(Suppl.4): 35-40, 1993.
  • Vandenberg T, Pritchard K, Eisenhauer E, Trudeau ME, Norris BD, Lopez P, Verma S, Buckman RA, Muldal A. Phase II study of weekly edatrexate as first line chemotherapy for metastatic breast cancer. A NCIC Clinical Trials Group Study. J Clin Oncol 11(7): 1241-4, 1993.
  • Verma S, Quirt IC, Eisenhauer E, Iscoe N, Young V, Bodurtha A, Davidson J. A phase II study of weekly edatrexate (10-EDAM) in metastatic melanoma. A NCIC Clinical Trials Group Study. Ann Oncol 4: 254-5, 1993.
  • Vermorken J, Ten Bokkel-Huinink W, Eisenhauer E, Favalli G, Belpomme D, Conte P, Kaye S. Carboplatin versus cisplatin in ovarian cancer. Ann Oncol 4(Suppl.4): 41-8, 1993.
  • Warr D, Willan A, Venner P, Pater J, Kaizer L, Laberge F, Latreille J, Stewart D, O'Connell G, Osoba D, Wilson K, Davis A, Johnston D. A randomised, double-blind comparison of granisetron with high dose metoclopramide, dexamethasone and diphenhydramine for cisplatin-induced emesis. Eur J Can 29A(1): 33-6, 1993.
  • Bow E, Pater J, Louie T, Feld R, Mandell L, Robson H, Chow A, Belch A, Miedzinski L, Paul N, Elliott C, Willan A. Reduction in clinical response to empiric antimicrobrial therapy of febrile granulocytopenic patients receiving trimethoprim/sulfamethoxazole for infection prophylaxis. Can J Infect Dis 3(5): 235-9, 1992.
  • Browman G, Belch A, Skillings J, Wilson K, Bergsagel D, Johnston D, Pater J. Modified adriamycin-vincristine-dexamethasone (M-VAD) in primary refractory and relapsed plasma cell myeloma: an NCI (Canada) pilot study. Br J Haematol 82: 555-9, 1992.
  • Eisenhauer E.A. New drug investigation in Canada: how card card-body bg-light well placed are we? Can J Oncol 2(1): 67-72, 1992.
  • Loehrer PJ, Sr., Einhorn LH, Elson PJ, Crawford DE, Kuebler P, Tannock I, Raghavan D, Stuart-Harris R, Sarosdy MF, Lowe BA, Blumenstein B, Trump D. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol 10(7): 1066-73, 1992.
  • Osoba D. The Quality of Life Committee of the NCIC Clinical Trials Group: organization and functions. Quality of Life Research 1: 211-8, 1992.
  • Paul N, Pater J. Industry involvement in cooperative oncology group studies: results of a survey of study nurses/institutional data managers. J Clin Res Pharmacoepidemiology 6: 39-46, 1992.
  • Sadura A, Pater J, Osoba D, Levine M, Palmer M, Bennett K. Quality of life assessment: patient compliance with questionnaire completion. J Natl Cancer Inst 84(13): 1023-6, 1992.
  • Shepherd F, Rusthoven J, Eisenhauer E, Goss P. Phase I trial of granulocyte, macrophage-colony stimulating factor with high dose cisplatin and etoposide for treatment of small cell lung cancer. A study of the NCIC Clinical Trials Group. J Natl Cancer Inst 84(1): 59-60, 1992.
  • Skillings J, Wierzbicki R, Eisenhauer E, Venner P, Letendre F, Stewart D, Weinerman B. A phase II study of recombinant tumour necrosis factor in renal cell carcinoma. J Immunother 11: 67-70, 1992.
  • Stewart D, Eisenhauer E, Skillings J, Pritchard K, Buckman R, Vandenberg T, Verma S, Aitken S, Norris B. Phase II study of oral menogaril as first line chemotherapy for advanced breast cancer. A NCIC Clinical Trials Group Study. Ann Oncol 3: 201-4, 1992.
  • Swenerton K, Jeffrey J, Stuart G, Roy M, Krepart G, Carmichael J, Drouin P, Stanimir R, O'Connell G, MacLean G, Kirk ME, Canetta R, Koski B, Shelley W, Zee B, Pater J. Cisplatin-cyclophosphamide versus carboplatin-cyclophosphamide in advanced ovarian cancer: A randomized phase III study of the NCIC Clinical Trials Group. J Clin Oncol 10(5): 718-26, 1992.
  • Weinerman B, Eisenhauer E, Stewart D, Mertens W, Tannock I, Venner P, Spaulding R. Phase II study of sulofenur (LY186641) in measurable metastatic renal cancer. A study of the NCIC Clinical Trials Group. Ann Oncol 3: 83-4, 1992.
  • Weinerman B, Shah A, Fields A, Cripps C, Wilson K, McCormick R, Temple W, Maroun J, Bogues W, Pater J, Zee B. Systemic infusion versus bolus chemotherapy with 5-fluorouracil in measurable metastatic colorectal cancer. Am J Clin Oncol 15(6): 518-23, 1992.
  • Calandra,T, Zinner,SH, Glauser,MP, Meunier,F, Viscoli,C, Feld,R, Gaya,H, Klastersky,J. Vancomycin added to empirical combination antibiotic therapy for fever in granulocytopenic cancer patients. J Infect Dis 163: 951-8, 1991.
  • Belch A, Bergsagel D, Wilson K, O'Reilly S, Wilson J, Sutton D, Pater J, Johnston D, Zee B. Effect of daily etidronate on the osteolysis of multiple myeloma. J Clin Oncol 9(8): 1397-402, 1991.
  • Eisenhauer E, Wierzbicki R, Knowling M, Bramwell V, Quirt I. Phase II trials of trimetrexate in advanced adult soft tissue sarcoma. Studies of the Canadian Sarcoma Group and the NCIC Clinical Trials Group. Ann Oncol 2: 689-90, 1991.
  • Erlichman C, Moore M, Kerr I, Wong B, Eisenhauer E, Zee B, Whitfield L. A phase I pharmacokinetic and pharmacodynamic study of a new anthrapyrazole CI-937 (DUP937). Cancer Research 6317-22, 1991.
  • Advanced Ovarian Cancer Trialists Group. Chemotherapy in advanced ovarian cancer: an overview of randomised clinical trials. Br Med J 303: 884-93, 1991.
  • Monga M, Carmichael J, Shelley W, Kirk M, Krepart G, Jeffrey JF, Pater J. Surgery without adjuvant chemotherapy for early epithelial ovarian carcinoma after comprehensive surgical staging. Gynecol Oncol 43: 195-7, 1991.
  • Pater J. Facilitation and funding of interface research. Can J Oncol 1(2): 45-9, 1991.
  • Quirt I, Shelley W, Pater J, Bodurtha A, McCulloch P, McPherson TA, Paterson A, Prentice R, Silver H, Willan A, Wilson K, Zee B. Improved survival in patients with poor-prognosis malignant melanoma treated with adjuvant levamisole: a phase III study by the NCIC Clinical Trials Group. J Clin Oncol 9(5): 729-35, 1991.
  • Rusthoven J, Pater J, Kaizer L, Wilson K, Osoba D, Latreille J, Findlay B, Lofters W, Warr D, Laberge F, Vandenberg T, Zee B, Goodlow J, Johnston D, Smaldone L. A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy. Ann Oncol 2: 681-6, 1991.
  • Rusthoven J, Levin L, Eisenhauer E, Mazurka J, Carmichael J, O'Connell G, Bryson P, Hirte H, Koski B. Two phase I studies of carboplatin dose escalation in chemotherapy-naive ovarian cancer patients supported with granulocyte-macrophage colony-stimulating factor. J Natl Cancer Inst 83(23): 1748-53, 1991.
  • Shepherd F, MacCormick R, Eisenhauer E. Phase II study of sulofenur (LY186641) in untreated patients with extensive small cell lung cancer. A study of the NCIC Clinical Trials Group. Ann Oncol 2: 772-3, 1991.
  • Skillings J, Levine M, Rayner H, Eisenhauer E, Erlichman C, Germond C, Kerr I, Lofters W, Maroun J, Yoshida S. Current Review. Levamisole and 5-fluorouracil therapy for resected colon cancer: a new indication. Can Med Assoc J 144: 297-301, 1991.
  • Skillings J, Cripps C, Eisenhauer E, Pater J, Verma S, Walde D. A phase II study of menogaril in low-grade non-Hodgkin's lymphoma. An NCI Canada Clinical Trials Group Study. Invest New Drugs 9: 79-82, 1991.
  • Venner P, Eisenhauer E, Wierzbicki R, Johnston J. Phase II study of 2'- deoxycoformycin in patients with renal cell carcinoma. A NCIC Clinical Trials Group Study. Invest New Drugs 9: 273-5, 1991.
  • Warr D, Willan A, Fine S, Wilson K, Davis A, Erlichman C, Rusthoven J, Lofters W, Osoba D, Laberge F, Latreille J, Pater J. Superiority of granisetron to dexamethasone plus prochlorperazine in the prevention of chemotherapy induced emesis. J Natl Cancer Inst 83(16): 1169-73, 1991.
  • Yelle L, Bergsagel D, Basco V, Brown T, Bush R, Gillies J, Israels L, Miller A, Rideout D, Whitelaw D, Willan A, Pater J. Combined modality therapy of Hodgkin's disease: ten-year results of NCIC Clinical Trials Group multicentre clinical trial. J Clin Oncol 9(11): 1983-93, 1991.
  • Blackstein M, Eisenhauer E, Wierzbicki R, Yoshida S. Epirubicin in extensive small-cell lung cancer: a phase II study in previously untreated patients: An NCI Canada Clinical Trials Group Study. J Clin Oncol 8(3): 385-9, 1990.
  • Cairncross G, Eisenhauer E, Macdonald DR, Rathbone M, Moore M, Sawka C, MacCormick R, Kerr I. Phase II study of trimetrexate in recurrent anaplastic glioma. An NCI Canada Clinical Trials Group Study. Can J Neurol Sci 17: 21-3, 1990.
  • Eisenhauer E, Pritchard K, Perrault D, Verma S, Pater J. Activity of intravenous menogaril in patients with previously untreated metastatic breast cancer. An NCI Canada Clinical Trials Group Study. Invest New Drugs 8: 283-7, 1990.
  • Evans W, Eisenhauer E, Cormier Y, Ayoub J, Wierzbicki R, Laberge F, Shepherd F. Phase II study of amonafide: results of treatment and lessons learned from the study of an investigational agent in previously untreated patients with extensive small-cell lung cancer. J Clin Oncol 8(3): 390-5, 1990.
  • Iscoe N, Eisenhauer E, Bodurtha A. Phase II study of trimetrexate in malignant melanoma: a NCIC Clinical Trials Group Study. Invest New Drugs 8: 121-3, 1990.
  • Jaakkimainen L, Goodwin P, Pater J, Warde P, Murray N, Rapp E. Counting the costs of chemotherapy in a NCIC Clinical Trials Group randomized trial in non-small cell lung cancer. J Clin Oncol 8(8): 1301-9, 1990.
  • Maroun J, Stewart D, Verma S, Evans WK, Eisenhauer E. Phase I study of acivicin and cisplatin in non-small cell lung cancer. Am J Clin Oncol (CCT)13(5): 401-4, 1990.
  • Bramwell V, Quirt I, Warr D, Verma S, Young V, Knowling M, Eisenhauer E. Combination chemotherapy with doxorubicin, dacarbazine, and ifosfamide in advanced adult soft tissue sarcoma. A Canadian Sarcoma-NCI Canada Clinical Trials Group Study. J Natl Cancer Inst 81(19): 1496-9, 1989.
  • O'Dwyer PJ, King SA, Eisenhauer E, Grem JL, Hoth DF. Hypersensitivity reactions to deoxycoformycin. Cancer Chemother Pharmacol 23: 173-5, 1989.
  • Belch A, Shelley W, Bergsagel D, Wilson K, Klimo P, White D, Willan A. A randomized trial of maintenance versus no maintenance melphalan and prednisone in responding multiple myeloma patients. Br J Cancer 57: 94-9, 1988.
  • Burns BF, Comrie W, Willan A, McCaughey WTE. Observer variation in the pathologic diagnosis of malignant lymphoma in Canada. Cancer 62: 314-8, 1988.
  • Coy P, Hodson I, Payne DG, Evans WK, Feld R, MacDonald AS, Osoba D, Pater J. The effect of dose of thoracic irradiation on recurrence in patients with limited stage small cell lung cancer. Initial results of a Canadian multicenter randomized trial. Int J Rad Oncol Biol Phys 14: 219-26, 1988.
  • Eisenhauer E, Zee B, Pater J, Walsh W. Trimetrexate: Predictors of severe or life-threatening toxic effects. J Natl Cancer Inst 80: 1318-22, 1988.
  • Eisenhauer EA, Evans WK, Murray N, Kocha W, Wierzbicki R, Wilson K. A phase II study of VP-16 and cisplatin in patients with unresectable malignant mesothelioma. An NCI Canada Clinical Trials Group Study. Invest New Drugs 6: 327-9, 1988.
  • Elliott C, Pater J. The effect of different measures of outcome on the results of studies of empiric antibiotic therapy in febrile neutropenic patients. Clin Invest Med 11(5): 327-30, 1988.
  • Evans W, Eisenhauer E, Hughes P, Maroun J, Ayoub J, Shepherd F, Feld R. VP-16 and carboplatin in previously untreated patients with extensive small cell lung cancer: a study of the NCIC Clinical Trials Group. Br J Cancer 58: 464-8, 1988.
  • Goodwin P, Feld R, Evans W, Pater J. Cost-effectiveness of cancer chemotherapy: an economic evaluation of a randomized trial in small cell lung cancer. J Clin Oncol 6(10): 1537-47, 1988.
  • Johnston J, Eisenhauer E, Corbett WEN, Scott J, Zaentz S. The efficacy of 2'-deoxycoformycin in hairy cell leukemia: a study of the NCIC Clinical Trials Group. J Natl Cancer Inst 80(10): 765-9, 1988.
  • Klaassen D, Shelley W, Starreveld A, Kirk M, Boyes D, Gerulath A, Levitt M, Fraser R, Carmichael J, Methot Y, Willan A. Early stage ovarian cancer: a randomized clinical trial comparing whole abdominal radiotherapy, melphalan, and intraperitoneal chromic phosphate: a NCIC Clinical Trials Group Report. J Clin Oncol 6(8): 1254-63, 1988.
  • Osoba D, Erlichman C, Willan A, Brigden ML, Geggie P, Pater J, Rusthoven J, Wilson KS. Failure of methylprednisolone acetate to prolong the antinauseant effect of intravenous methylprednisolone sodium succinate in patients receiving chemotherapy. Clin Invest Med 11(5): 377-9, 1988.
  • Perrault D, Logan DM, Stewart D, Bramwell V, Paterson AHG, Eisenhauer E. Phase II study of flutamide in patients with metastatic breast cancer. A NCIC Clinical Trials Group Study. Invest New Drugs 6: 207-10, 1988.
  • Rapp E, Pater J, Willan A, Cormier Y, Murray N, Evans WK, Hodson I, Clark D, Feld R, Arnold A, Ayoub J, Wilson KS, Latreille J, Wierzbicki RF, Hill D. Chemotherapy can prolong survival in patients with advanced non- small-cell lung cancer -- report of a Canadian multicenter randomized trial. J Clin Oncol 6(4): 633-41, 1988.
  • Ross W, Carmichael J, Shelley W. Advanced carcinoma of the ovary with central nervous system relapse. Gynecol Oncol 30: 398-406, 1988.
  • Shelley W, Carmichael J, Brown L, Fraser R, Kirk M, Krepart G, Levitt M, Roy M, Willan A, Wilson K. Adriamycin and cisplatin in the treatment of stage III and IV epithelial ovarian carcinoma. Gynecol Oncol 29: 208-21, 1988.
  • Shelley W, Starreveld A, Carmichael J, O'Connell G, Roy M, Swenerton K. Toxicity of abdominopelvic radiation in advanced ovarian carcinoma patients after cisplatin/cyclophosphamide therapy and second-look laparotomy. Obstet Gynecol 71(3): 327-32, 1988.
  • Temple WJ, Bramwell V, Eisenhauer E, Jenkin RDT, Langer F, Worth AJ. Guidelines for the surgical management of soft-tissue sarcoma. Report of the Canadian Sarcoma Group. Can J Surg 31(6): 410-2, 1988.
  • Willan A. Using the maximum test statistic in the two-period crossover clinical trial. Biometrics 44: 211-8, 1988.
  • Carmichael J, Shelley W, Brown L, Fraser R, Kirk M, Krepart G, Levitt M, Roy M, Willan A, Wilson KS. A predictive index of cure versus no cure in advanced ovarian carcinoma patients -- replacement of second-look laparotomy as a diagnostic test. Gynecol Oncol 27: 269-78, 1987.
  • Eisenhauer E, Maroun J, Fields A, Walde PLD. Phase II study of acivicin as a 72-hr continuous infusion in patients with untreated colorectal cancer. A NCIC Clinical Trials Group Study. Invest New Drugs 5: 375-8, 1987.
  • Eisenhauer E, Silver K, Venner P, Thirlwell M, Weinerman B, Coppin C. Phase II study of high dose weekly intravenous human lymphoblastoid interferon in renal cell carcinoma. Br J Cancer 55: 541-2, 1987.
  • Evans W, Feld R, Murray N, Willan A, Coy P, Osoba D, Shepherd F, Clark D, Levitt M, MacDonald A, Wilson K, Shelley W, Pater J. Superiority of alternating non-cross-resistant chemotherapy in extensive small cell lung cancer. Ann Intern Med 107: 451-8, 1987.
  • Feld R, Evans WK, Coy P, Hodson I, MacDonald A, Osoba D, Payne D, Shelley W, Pater J. Canadian multicentre randomized trial comparing sequential and alternating administration of two non-cross-resistant chemotherapy combinations in patients with limited small-cell carcinoma of the lung. J Clin Oncol 5(9): 1401-9, 1987.
  • Hollinshead A, Stewart THM, Takita H, Dalbow M, Concannon J. Adjuvant specific active lung cancer immunotherapy trials. Cancer 60: 1249-62, 1987.
  • Jolivet J, Landry L, Pinard MF, McCormack JJ, Tong WP, Eisenhauer E. A phase I study of trimetrexate, an analog of methotrexate, administered monthly in the form of nine consecutive daily bolus injections. Cancer Chemother Pharmacol 20: 169-72, 1987.
  • Maroun J, Eisenhauer E, Cripps C, Maksymiuk A. Phase II study of tiazofurin in colorectal cancer. Cancer Treat Rep 71(12): 1297-8, 1987.
  • McCulloch P, Eisenhauer E, Shibata H, Young V. Phase II study of intravenous menogaril in patients with malignant melanoma: a NCIC Clinical Trials Group study. Cancer Treat Rep 71(7-8): 771-2, 1987.
  • O'Connell G, Shelley W, Carmichael J, Fraser R, Kirk M, Krepart G, Levin L, Swenerton K. High dose intensity regimen of weekly doxorubicin and cisplatin in the treatment of patients with stage III and IV epithelial ovarian carcinoma. Cancer Treat Rep 71(5): 455-8, 1987.
  • Pater J, Carmichael J, Krepart G, Fraser R, Roy M, Kirk M, Levitt M, Brown L, Wilson K, Shelley W, Willan A. Second line chemotherapy of stage III-IV ovarian carcinoma: A randomized comparison of melphalan to melphalan and hexamethylmelamine in patients with persistent disease after doxorubicin and cisplatin. Cancer Treat Rep 71(3): 277-81, 1987.
  • Quirt I, Eisenhauer E, Bramwell V, Knowling M, Grafton C, Hirte W, Cripps M, Maksymiuk A. Phase II study of mitroxantrone in untreated and previously minimally treated patients with metastatic soft tissue sarcomas. Cancer Treat Rep 71(11): 1109-10, 1987.
  • Wilson K, Shelley W, Belch A, Brandes L, Bergsagel D, Klimo P, White D, Willan A. Weekly cyclophosphamide and alternate-day prednisone: an effective secondary therapy in multiple myeloma. Cancer Treat Rep 71(10): 981-2, 1987.
  • Band P, Maroun J, Pritchard K, Stewart D, Coppin C, Wilson K, Eisenhauer E. Phase II study of lonidamine in patients with metastatic breast cancer. Cancer Treat Rep 70(11): 1305-10, 1986.
  • Eisenhauer E, Weinerman B, Kerr I, Quirt I. Toxicity of oral N-methylformamide in three phase II trials. A report from the NCI Canada Clinical Trials Group. Cancer Treat Rep 70(7): 881-3, 1986.
  • Eisenhauer E, Evans W, Raghavan D, Desmeules M, Murray N, Stuart-Harris R, Wilson K. Phase II study of mitoxantrone in patients with mesothelioma: a NCI Canada Clinical Trials Group study. Cancer Treat Rep 70(8): 1029-30, 1986.
  • Eisenhauer E, Swenerton K, Sturgeon J, Fine S, O'Reilly S. Phase II study of carboplatin in patients with ovarian carcinoma. An NCI Canada Clinical Trials Group Study. Cancer Treat Rep 70: 1195-8, 1986.
  • Evans W, Feld R, Murray N, Pater J, Shelley W, Willan A, Osoba D, Levitt M, Coy P, Hodson I, Payne D, MacDonald A. The use of VP-16 plus cisplatin during induction chemotherapy for small-cell lung cancer. Semin Oncol 13: 10-6, 1986.
  • Maroun J, Maksymiuk A, Eisenhauer E, Stewart D, Young V, Pater J. Phase II study of acivicin in non-small cell lung cancer. A Canadian National Cancer Institute study. Cancer Treat Rep 70(11): 1327-8, 1986.
  • Osoba D, Erlichman C, Willan A, Levitt M, Pater J. Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy. Clin Invest Med 9(4): 225-31, 1986.
  • Pater J, Eisenhauer E, Shelley W, Willan A. Testing hypotheses in clinical trials: Experience of the NCIC Clinical Trials Group (letter to the editor). Cancer Treat Rep 70(9): 1133-6, 1986.
  • Pater J, Weir L. Reporting the results of randomized trials of empiric antibiotics in febrile neutropenic patients -- a critical survey. J Clin Oncol 4(3): 346-52, 1986.
  • Sawka CA, Pritchard KI, Paterson AHG, Sutherland DJA, Thomson DB, Shelley WE, Myers RE, Mobbs BG, Malkin A, Meakin JW. Role and mechanism of action of tamoxifen in premenopausal women with metastatic breast carcinoma. Cancer Research 46: 3152-6, 1986.
  • Weinerman B, Eisenhauer E, Besner JG, Coppin C, Stewart D, Band P. Phase II study of lonidamine in patients with metastatic renal cell carcinoma: a NCIC Clinical Trials Group study. Cancer Treat Rep 70(6): 751-4, 1986.
  • Willan A, Pater J. Using baseline measurements in the two period crossover clinical trial. Controlled Clin Trials 7(4): 282-9, 1986.
  • Willan A, Pater J. Carryover and the two period crossover clinical trial. Biometrics 42(3): 593-9, 1986.
  • Eisenhauer E, Kerr I, Bodurtha A, Iscoe N, McCulloch P, Pritchard K, Quirt I. A phase II study of spirogermanium in patients with metastatic malignant melanoma. An NCI Canada Clinical Trials Group Study. Invest New Drugs 3: 303-5, 1985.
  • Eisenhauer E, Quirt I, Connors JM, Maroun J, Skillings J. A phase II study of spirogermanium as second line therapy in patients with poor prognosis lymphoma. An NCI Canada Clinical Trials Group Study. Invest New Drugs 3: 307-10, 1985.
  • Feld R, Louie TJ, Mandell L, Bow EJ, Robson HG, Chow A, Belch A, Miedzinski L, Rachlis A, Pater J, Willan A. A multicentre comparative trial of tobramycin and ticarcillin versus moxalactam and ticarcillin in febrile neutropenic patients. Arch Intern Med 145: 1083-8, 1985.
  • Klaassen D, Starreveld A, Shelley W, Miller A, Boyes D, Gerulath A, Levitt M. External beam pelvic radiotherapy plus intraperitoneal radioactive chronic phosphate in early stage ovarian cancer: a toxic combination. Int J Rad Oncol Biol Phys 11: 1801-4, 1985.
  • Shelley W, Quirt I, Bodurtha A, Iscoe N, Russell J, Paterson A, Young V. Lomustine, vincristine and procarbazine in the treatment of metastatic malignant melanoma. Cancer Treat Rep 69(9): 941-4, 1985.
  • Willan A, Pater J. Hypothesis testing and sample size for bivariate binomial response in the comparison of two groups. J Chron Dis 38(7): 603-8, 1985.
  • Eisenhauer E, Bowman D, Pritchard K, Paterson AHG, Ragaz J, Geggie P, Maxwell I. Tamoxifen and conjugated estrogens (premarin) followed by sequenced methotrexate and 5-fluorouracil in refractory advanced breast cancer. Cancer Treat Rep 68(11): 1421-2, 1984.
  • Maroun JA, Fields AL, Pater JL, Stewart DJ, Cripps C, Eisenhauer E. Phase II study of acivicin in colorectal carcinoma: a NCIC Clinical Trials Group study. Cancer Treat Rep 68(9): 1121-3, 1984.
  • Moher D, Arthur AZ, Pater JL. Anticipatory nausea and/or vomiting. Can Treat Rev 11: 257-64, 1984.
  • Quirt IC, Shelley WE, Osoba D, Dent PB, McCulloch PB, Paterson AHG, Evans WK, Shepherd FA, Baker ML, Bodurtha AJ, Norvell ST, Maroun JA, Thirlwell MP, Weinerman B, Schipper H, Wilson KS, Nimmagadda RBV, Gapski JAP, Pritchard KI, Walde PLD, Duffin JM, Aitken SE. Vinblastine, bleomycin and cis-platinum for the treatment of metastatic malignant melanoma. NCIC Clinical Trials Group Melanoma Group. J Clin Oncol 2: 131-4, 1984.
  • Pater J, Willan A. Clinical trials as diagnostic tests. Controlled Clin Trials 5: 107-13, 1984.
  • Pater J, Willan A. Methodologic issues in trials of antiemetics. J Clin Oncol 2(5): 484-7, 1984.
  • Riopelle RJ, Dow KE, Eisenhauer E. Some observations on vinca alkaloid and ethanol neurotoxicity using dissociated neuronal cultures. Can J Physiol Pharmacol 62: 1032-6, 1984.
  • Shelley W, Kersey P, Quirt I, Pater J. Survey of surgical management of malignant melanoma in Canada: optimal margins of excision and lymph-node dissection. Can J Surg 27(2): 190-2, 1984.
  • Miller AB, Klaassen DJ, Boyes DA, Dodds DJ, Gerulath A, Kirk ME, Levitt M, Pearson JG, Wall C. Combination v. sequential therapy with melphalan, 5-fluorouracil and methotrexate for advanced ovarian cancer. Can Med Assoc J 123: 365-71, 1980.
  • Bergsagel D, Bailey A, Langley G, MacDonald R, White D, Miller A. The chemotherapy of plasma-cell myeloma and the incidence of acute leukemia. N Engl J Med 301: 743-8, 1979.