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2011

Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

16 Dec 2011

Ethics Regulatory

Site Notification of Study Closed to Accrual form
The Safety Desk has replaced the 'Site Notification of Study Closed to Accrual' form with a generic 'Notification of Unreported SAE/SU/IB/PM to Local REB' form.
Read more ....

General

Bulletin in 2012
The first Bulletin of 2012 will be sent on Friday, January 6, 2012.
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ECCO-AACR-EORTC-ESMO Workshop
The ECCO-AACR-EORTC-ESMO Workshop on Methods in Clinical Cancer Research is scheduled for 23-29 June 2012 in Waldhaus Flims, Switzerland, and is now accepting applications.
Read more ....

Canadian Cancer Trials Group Holiday Closure
The Canadian Cancer Trials Group Central Office will be closed with limited staff over the holidays beginning December 24, 2011. Web-based applications (i.e. MANGO, GCP) will be available. Please see the Canadian Cancer Trials Group website ... www.ctg.queensu.ca ... for complete information.
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Cooperative Group Holiday Closures
We are currently collecting and collating cooperative groups' holiday closures. A link to this information is available on the main Canadian Cancer Trials Group website at www.ctg.queensu.ca.
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Recent Publication
Final results of Canadian Cancer Trials Group HD.6 were published online in the NEJM and are featured in the recent edition of the NCI Bulletin.
Read more ....

Happy Holidays and Happy New Year!!!!
On behalf of everyone at Canadian Cancer Trials Group's Central Office, we would like to wish everyone a very Merry Christmas, Happy Holidays, and Happy New Year. All the best for a restful and peaceful holiday season.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group OV.18 (MRC ICON6) -- A Randomized Trial of Concurrent Cediranib [AZD2171] (with Platinum-Based Chemotherapy) and Maintenance Cediranib in Women with Platinum-Sensitive Relapsed Ovarian Cancer -- was closed to accrual on 14 December 2011.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Special Bulletin

Canadian Cancer Trials Group Special Bulletin

11 Dec 2011

General

Canadian Cancer Trials Group HD.6 in NEJM
Final results of Canadian Cancer Trials Group HD.6 -- Randomized Comparison of ABVD Chemotherapy with a Strategy that Includes Radiation Therapy (RT) in Patients with Limited-Stage Hodgkin Lymphoma -- were presented at ASH today and published online in the NEJM.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

02 Dec 2011

EDC - Rave

Roster Office Reminders
So that centres do not experience delays when randomizing patients or accessing specific Canadian Cancer Trials Group resources over the Christmas holidays, we encourage centres to update trial Participant Lists and request website, MANGO and EDC access prior to December 16.
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General

San Antonio Breast Cancer Symposium
Several Canadian Cancer Trials Group abstracts are being presented at the 34th Annual San Antonio Breast Cancer Symposium being held December 6-10, 2011 in San Antonio, Texas.
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Roster Office Reminders
Recently, some of our Centre Participants have been receiving notification messages from the CTSU reminding them that they must be registered as an affiliate. Our Roster Office Staff are pleased to facilitate this for our trial participants.
Read more ....

Trial Activation
One trial, Canadian Cancer Trials Group IND.207 -- A Phase II Study of PF-03446962 in Patients with Advanced Malignant Pleural Mesothelioma -- was centrally activated on November 30, 2011.
Read more ....

American Society of Hematology (ASH) Annual Meeting
Several Canadian Cancer Trials Group abstracts will be presented at the 53rd ASH Annual Meeting and Exposition being held December 10-13, 2011 in San Diego, California. For a complete listing follow this link ... http://www.ctg.queensu.ca/public/publications/publications.h tml
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group MA.31 -- A Randomized, Open-Label, Phase III Study of Taxane-Based Chemotherapy with Lapatinib or Trastuzumab as First-Line Therapy for Women with HER2/neu Positive Metastatic Breast Cancer -- was closed to accrual on December 1, 2011.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

18 Nov 2011

EDC - Rave

EDC SAE Notification Form
A reminder to please ensure that EDC SAE Notification Forms are successfully submitted to Canadian Cancer Trials Group Central Office. If successful, you will receive email confirmation that the form has been received.
Read more ....

Ethics Regulatory

Ethics Research Associate Assignments
The Ethics contact has changed for some centres. Please visit the Ethics Research Associate Centre Assignment page: http://www.ctg.queensu.ca/private/compliance/ethics/centre_assignments.html for an updated listing.
Read more ....

Finance and Operations

Trials Closed to Accrual
Two trials -- Canadian Cancer Trials Group HN.6 and IND.195 -- have recently been closed to accrual. In addition, Randomization #1 only for Canadian Cancer Trials Group LY.12 has been closed to accrual. Randomization #2 to maintenance therapy remains open.
Read more ....

General

Recent Publications
There were five recent publications -- one related to Canadian Cancer Trials Group MA.17, one related to Canadian Cancer Trials Group MA.5, two methodological publications, and one general publication discussing RCTs and molecular oncology.
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Central Office Fellow Wins Award
Dr. Bin Dong, a Postdoctoral Fellow at Canadian Cancer Trials Group's Central Office, received an AACR Scholar-in-Training Award to present her first authorship work.
Read more ....

Trial Management Group

Canadian Cancer Trials Group CRA Executive Committee
The Canadian Cancer Trials Group Clinical Research Associates Executive Committee (CRAEC) is seeking new members!
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

04 Nov 2011

Ethics Regulatory

Single-Study Centres and DSMC Summary Reports
The Canadian Cancer Trials Group's Data Safety Monitoring Committee met via teleconference on 24 October 2011. Trial-specific DSMC Summary Reports are now posted on trial websites.
Read more ....

General

PR.3 in the News ... Again!
Interim results of Canadian Cancer Trials Group PR.3 combining radiation and hormone therapy in patients with high risk prostate cancer show it significantly improves the likelihood of patients living longer. The results were just published in The Lancet.
Read more ....

Recent Publication
A meta-analysis, including Canadian Cancer Trials Group MA.5, Intensive CEF versus Standard CMF as Adjuvant Therapy For Breast Carcinoma In Premenopausal Patients With Histologically-Involved Axillary Nodes, was recently published in The Lancet Oncology.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group IND.199 - Phase II Study of Temsirolimus (NSC 683864), an mTOR Inhibitor, in Patients with Recurrent, Unresectable, Locally Advanced or Metastatic Carcinoma of the Cervix, was closed to accrual October 27, 2011.
Read more ....

BARL Holiday Closure
Please be advised that Canadian Cancer Trials Group's drug distribution partner, Bay Area Research Logistics, will be closed on Friday, November 11th, 2011 in recognition of Remembrance Day. BARL will resume operating on Monday, November 14th, 2011.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

21 Oct 2011

General

Recent Publication
The primary results of Canadian Cancer Trials Group IND.183 (A Phase II Study of Sunitinib in Patients with Advanced Malignant Pleural Mesothelioma) were published in the Journal of Thoracic Oncology.
Read more ....

Maria Ricci Memorial Lectureship in Medical Oncology
Dr. Joseph Connors is this year's guest speaker for the Maria Ricci Memorial Lectureship in Medical Oncology being held 16 November 2011 at the Cancer Research Institute, Queen's University.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group ALC.2 (CALGB 10603) trial has met its accrual goal and has been closed to accrual.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

08 Oct 2011

General

Maria Ricci Memorial Lectureship in Medical Oncology
Dr. Joseph Connors is this year's guest speaker for the Maria Ricci Memorial Lectureship in Medical Oncology being held 16 November 2011 at the Cancer Research Institute, Queen's University.
Read more ....

Recent Publication
A publication related to LY.9 was recently published in The Lancet Oncology.
Read more ....

Canadian Cancer Trials Group Office Closure
The Canadian Cancer Trials Group will be closed Monday, October 10, 2011 for Thanksgiving.
Read more ....

Trial Management Group

Trial Activations
Two trials were recently activated -- Canadian Cancer Trials Group CEC.3 (NCCTG N107C) and Canadian Cancer Trials Group MAC.15 (SWOG S1007).
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

07 Oct 2011

General

Maria Ricci Memorial Lectureship in Medical Oncology
Dr. Joseph Connors is this year's guest speaker for the Maria Ricci Memorial Lectureship in Medical Oncology being held 16 November 2011 at the Cancer Research Institute, Queen's University.
Read more ....

Recent Publication
A publication related to LY.9 was recently published in The Lancet Oncology.
Read more ....

Canadian Cancer Trials Group Office Closure
The Canadian Cancer Trials Group will be closed Monday, October 10, 2011 for Thanksgiving.
Read more ....

Trial Management Group

Trial Activations
Two trials were recently activated -- Canadian Cancer Trials Group CEC.3 (NCCTG N107C) and Canadian Cancer Trials Group MAC.15 (SWOG S1007).
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Special Bulletin

28 Sep 2011

General

Planned Power Outage Notification
On Tuesday October 4, 2011, beginning at 12:01 am EDT (4:01 am GMT), all Canadian Cancer Trials Group's IT systems will be unavailable due to a planned power outage. Systems offline will include EDC, web sites, email, and MANGO.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

23 Sep 2011

Audit Monitoring Group

GCP Refresher Training and Composite Certificates
A reminder that GCP composite certificates documenting all modules completed by Canadian Cancer Trials Group members can be accessed by individuals and by Centre Representatives and Contact CRAs for members at their centres.
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General

Recent Publications
There were two recent publications -- one reporting the primary results of Canadian Cancer Trials Group MA.14, and the other related to Canadian Cancer Trials Group OV.17 (CALYPSO).
Read more ....

Canadian Cancer Trials Group Office Closure
The Canadian Cancer Trials Group will be closed Monday, October 10, 2011 for Thanksgiving. Regular business hours will resume on Tuesday, October 11 at 8:00 am EDT.
Read more ....

Gynecology Publications
The 4th Ovarian Cancer Consensus Conference was held in Vancouver, Canada, in June 2010. A number of publications that included the participation of members of the Canadian Cancer Trials Group came out of that conference and were published in the Int J Gyn Cancer.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

09 Sep 2011

Ethics Regulatory

De-Identifying Supporting Documents
Canadian Cancer Trials Group would like to remind centres to ensure that all patient identifiers are removed from source documents before they are submitted to Central Office.
Read more ....

General

Recent Publication
An abstract related to Canadian Cancer Trials Group MA.14 -- A Randomized Trial of Antiestrogen Therapy versus Combined Antiestrogen and Octreotide Lar Therapy in the Adjuvant Treatment of Breast Cancer in Post-Menopausal Women -- was recently published in JCO.
Read more ....

Trial Management Group

Canadian Cancer Trials Group CO.21 100th Participant Randomized!
Congratulations to the Grand River Regional Cancer Centre for randomizing the Challenge Trial's (Canadian Cancer Trials Group CO.21) 100th participant this week.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

26 Aug 2011

Ethics Regulatory

Reminder -- EDC and SAE Reporting
For those trials using RAVE Electronic Data Capture (EDC), the Serious Adverse Event (SAE) Notification Form must be completed when submitting an SAE (including for revisions and follow up information) to Canadian Cancer Trials Group.
Read more ....

Informed Consent and Local Consent Form Requirements
A memo clarifying Canadian Cancer Trials Group policies regarding delegation of obtaining informed consent and local consent form requirements has been posted to the Canadian Cancer Trials Group ethics website.
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Changes to the Ethics Research Associate Centre Assignments
Due to staffing changes in the Ethics and Regulatory Group, some centres' ethics research contacts have changed.
Read more ....

General

Recent Publications
There were two recent publications, including one reporting results of Canadian Cancer Trials Group BL.10 (USC: 4B951) in the Journal of Clinical Oncology.
Read more ....

OICR at Canadian Cancer Trials Group to Announce $12.6M for HICT
A press conference was held at the Canadian Cancer Trials Group Central Office on Monday, August 22 to officially announce $12.6 million in funding over four years for OICR's High Impact Clinical Trials (HICT) Program.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

12 Aug 2011

General

Recent Publication
The primary publication for Canadian Cancer Trials Group LY.13 was recently published online in the Journal of Clinical Oncology.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

29 Jul 2011

Ethics Regulatory

Updated CTEP Adverse Event Guidelines
Effective July 26, 2011, the document NCI Guidelines for Investigators: Adverse Event Reporting Requirements for DCTD (CTEP AND CIP) and DCP INDs and IDEs has been updated.
Read more ....

Finance and Operations

Holiday Closure
Monday, August 1, 2011 is a Civic Holiday (in Canada), and the Canadian Cancer Trials Group will be closed. MANGO Patient Allocation System will be available. Regular business hours will resume on Tuesday, August 2 at 8:00 am EDT.
Read more ....

2011 Spring Meeting Expense Claims
If you received a full-funded invitation to the 2011 Spring Meeting of Participants, the deadline for submitting your expense claim is 31 July 2011. Any claims received after 31 July 2011 will not be processed and will be returned.
Read more ....

General

Recent Update to CV Reminder Program
The automated semi-annual CV reminders will now also be sent to the Ethics Representative at each participating Canadian Cancer Trials Group Member Centre in addition to the Centre's Contact CRA.
Read more ....

Recent Publication
The primary publication for IND.160 -- A Phase II Study of Sunitinib or Temsirolimus in Patients with Advanced Rare Tumours -- was recently published in the Journal of Clinical Oncology.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

15 Jul 2011

Finance and Operations

Canadian Cancer Trials Group Gynecology Site Committee Leadership
Drs Gavin Stuart and Amit Oza will be stepping down as Co‐Chairs of the Canadian Cancer Trials Group's Gynecology Site Committee. We are extremely grateful to them both for their leadership over the past many years and look forward to continued collaborations.
Read more ....

Trial Management Group

SC.23 Meets Its Monthly Target Accrual
SC.23 (A Phase III Double-Blind Study of Dexamethasone versus Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy for Bone Metastases) met its monthly target accrual in June 2011 after local activations started.
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Trial Activations
Two trials were recently activated -- Canadian Cancer Trials Group IND.206 and Canadian Cancer Trials Group NEC.2 (CALGB 80701).
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

30 Jun 2011

Finance and Operations

2011 Spring Meeting Expense Claims and the Postal Strike
If you received a full-funded invitation to the 2011 Spring Meeting of Participants, due to the strike at Canada Post, the deadline for submitting your expense claim has been extended to 31 July 2011.
Read more ....

General

Canadian Cancer Trials Group Holiday Closure
The Canadian Cancer Trials Group will be closed on Friday, July 1, 2011 in observance of Canada Day. Regular business hours will resume on Monday, July 4 at 8:00 am EDT.
Read more ....

CO.21 Canadian Cancer Trials Group Requirements for Trial Conduct -- Ethics
A brief document clarifying the ethics requirements for the Canadian Cancer Trials Group CO.21 trial has been posted to the trial website.
Read more ....

Trial Management Group

Trial Activation
One trial was recently activated -- Canadian Cancer Trials Group MAC.14 (ECOG 2108): A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

17 Jun 2011

Ethics Regulatory

Changes to the Ethics RA Centre Assignments
Due to staffing changes in the Ethics and Regulatory Group, some centres' ethics research contacts have changed.
Read more ....

Finance and Operations

EDC Supplemental Funding
The Electronic Data Capture (EDC) supplemental funding program for Canadian Cancer Trials Group Canadian member sites will come to an end December 31, 2011.
Read more ....

General

MOCOMP Credits from Spring Meeting -- LAST CALL
The deadline to obtain your MOCOMP certificate for credits from the Canadian Cancer Trials Group Spring Meeting is 22 JUNE 2011.
Read more ....

Canadian Cancer Trials Group MAP.3 Results Presented at ASCO
Final results of Canadian Cancer Trials Group MAP.3 show that exemestane significantly reduces risk of invasive breast cancer in high-risk, postmenopausal women.
Read more ....

Canadian Cancer Trials Group Holiday Closure and Next Bulletin
The Canadian Cancer Trials Group will be closed on Friday, July 1, 2011 in observance of Canada Day. Regular business hours will resume on Monday, July 4 at 8:00 am EDT. As a result, the next Bulletin will be sent on Thursday, June 30, 2011.
Read more ....

More Canadian Cancer Trials Group-Related ASCO Abstracts
In addition to the 27 abstracts presented at the American Society of Clinical Oncology Annual Meeting and identified in the previous Bulletin, an additional 10 abstracts related to trials that included Canadian Cancer Trials Group participation were presented.
Read more ....

2011 Spring Meeting Expense Claims and the Postal Strike
If you received a full-funded invitation to the 2011 Spring Meeting of Participants, please note that due to the strike at Canada Post, the deadline for submitting your expense claim has been extended.
Read more ....

Recent Publications
There were two recent publications both reporting primary results -- Canadian Cancer Trials Group MAP.3 published in the New England Journal of Medicine, and Canadian Cancer Trials Group IND.188 published in the British Journal of Cancer.
Read more ....

Canadian Cancer Trials Group MA.20 Results Presented at ASCO
Interim results of Canadian Cancer Trials Group MA.20 show that adding regional nodal irradiation decreases recurrences in women with early, high-risk breast cancer.
Read more ....

Results of Canadian Cancer Trials Group PR.7 Presented at ASCO
Results from Canadian Cancer Trials Group PR.7 show that men with prostate cancer who are treated with intermittent courses of androgen-suppressing therapy will live as long as those receiving continuous therapy.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

03 Jun 2011

General

Recent Publications
There were two recent publications -- the primary publication for Canadian Cancer Trials Group PRP.1 and another publication related to Canadian Cancer Trials Group MA.5.
Read more ....

MOCOMP Credits from Spring Meeting -- REMINDER
We were very pleased to have had the Canadian Cancer Trials Group 2011 Spring Meeting of Participants accredited as an educational event under Section 1 of the Maintenance of Certification Program.
Read more ....

Canadian Cancer Trials Group MA.32 in NCI Cancer Bulletin
Canadian Cancer Trials Group MA.32 -- A Phase III Randomized Trial of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer -- is highlighted in the current edition of the NCI Cancer Bulletin.
Read more ....

ASCO 2011
Twenty-seven abstracts related to Canadian Cancer Trials Group trials or trials which included Canadian Cancer Trials Group participation are being presented at the ASCO Annual Meeting in Chicago, IL, June 3-7, 2011, including three that have been chosen as "Best of ASCO".
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin - Special Edition

Canadian Cancer Trials Group Bulletin

Special Edition

01 Jun 2011

General

ASCO 2011
Twenty-seven abstracts related to Canadian Cancer Trials Group trials or trials which included Canadian Cancer Trials Group participation are being presented at the ASCO Annual Meeting in Chicago, IL, June 3-7, 2011, including three that have been chosen as "Best of ASCO".
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

20 May 2011

Finance and Operations

2011 Spring Meeting Expense Claims
If you received a full-funded invitation to the 2011 Spring Meeting of Participants, please read the following carefully:
Read more ....

General

New Investigator Clinical Trials Course
Applications to attend the Canadian Cancer Trials Group's New Investigator Clinical Trials Course are now being accepted.
Read more ....

Single-Study Centres and DSMC Summary Reports
Trial-specific DSMC Summary Reports are now posted on trial websites. Single-study centres participating on these trials should download these reports and submit them to their Research Ethics Boards.
Read more ....

Trial Management Group

Bay Area Research Labs Holiday Closure
Please be advised that Bay Area Research Labs will be closed on Victoria Day, Monday, May 23.
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Trial Closures
There were two recent trial closures -- Canadian Cancer Trials Group PR.11 and Canadian Cancer Trials Group SC.22.
Read more ....

Canadian Cancer Trials Group MA.32
We are very pleased to announce that beginning next week, CTSU sites will be able to enroll their first patients onto Canadian Cancer Trials Group MA.32 -- A Phase III Randomized Trial of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

06 May 2011

Ethics Regulatory

Updates to the Web-Based Ethics Utility
Some minor updates have been made to the web-based ethics utility.
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General

Recent Publication
The primary results for Canadian Cancer Trials Group IND.182 (A Phase II Study of Sunitinib (SU11248; NSC 736511; IND 74019), an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma) were recently published.
Read more ....

2011 Spring Meeting Expense Claims
If you received a full-funded invitation to the 2011 Spring Meeting of Participants, please read the following carefully:
Read more ....

Canadian Cancer Research Conference
The Canadian Cancer Research Alliance has begun planning for its first ever Canadian Cancer Research Conference scheduled for November 27-30, 2011 in Toronto.
Read more ....

Obtaining MOCOMP Credits from Spring Meeting Sessions
For information on how to obtain your Accreditation Certificate, please read more ...
Read more ....

Victoria Day Closure
The Canadian Cancer Trials Group will be closed on Monday, May 23, 2011 to celebrate Victoria Day. Regular business hours will resume on Tuesday, May 24 at 8:00 am EDT.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

21 Apr 2011

Finance and Operations

Holiday Closure
The Canadian Cancer Trials Group will be closed on Friday, April 22, 2011 for Good Friday. Regular business hours will resume on Monday, April 25 at 8:00 am EDT.
Read more ....

General

2011 Spring Meeting Trial Reports - REMINDER
Once again, we will not be producing a paper meeting book. The 2011 Spring Meeting Trial Reports are now posted on the Canadian Cancer Trials Group members-only website using this link ... http://www.ctg.queensu.ca/trials/.
Read more ....

2011 Spring Meeting of Participants -- General Reminders
The Canadian Cancer Trials Group 2011 Spring Meeting of Participants will be held 29 April - 1 May at the Delta Chelsea Hotel in Toronto. Please read more for reminders and information.
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2011 Spring Meeting Event -- Cosbie Lecture
We are very pleased to announce Dr. Bernard Cummings as the 2011 "Cosbie Lecturer".
Read more ....

Spring Meeting -- Registration
On-line registration for the 2011 Spring Meeting of Participants will be closed at 4:00 pm on Monday, 25 April. If you have not already registered, you should do so as soon as possible.
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Wireless Internet at Spring Meeting
Free wireless internet will be available throughout the meeting space at the Delta Chelsea Hotel during the Canadian Cancer Trials Group 2011 Spring Meeting of Participants.
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Recent Publications
There were two recent publications -- the primary publication for Canadian Cancer Trials Group IND.172, and a meta-analysis which included Canadian Cancer Trials Group BR.10.
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Spring Meeting 2011 -- Industry Sponsorship
This year, the Canadian Cancer Trials Group is pleased to offer our industry partners an opportunity for display / exhibition booths to provide educational materials that are related to clinical investigation and patient care.
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Accreditation of Spring Meeting 2011
The Canadian Cancer Trials Group Spring Meeting of Participants has been accredited as an educational event under Section 1 of the Maintenance of Certification Program.
Read more ....

Trial Management Group

CRA Program and Spring Meeting 2011
The Clinical Research Associates Steering Group (CRASG) is pleased to announce a new program of CRA activities for this year's Spring Meeting of Participants.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

08 Apr 2011

General

Holiday Closure
The Canadian Cancer Trials Group will be closed on Friday, April 22, 2011 for Good Friday. Regular business hours will resume on Monday, April 25 at 8:00 am EDT.
Read more ....

Next Bulletin
The next Canadian Cancer Trials Group Bulletin will be sent on Thursday, April 21.
Read more ....

Canadian Cancer Research Conference
The Canadian Cancer Research Alliance has begun planning for its first ever Canadian Cancer Research Conference scheduled for November 27-30, 2011 in Toronto.
Read more ....

Recent Publications
There were two recent publications -- the primary publication for Canadian Cancer Trials Group IND.179 and one related to Canadian Cancer Trials Group OV.21.
Read more ....

2011 Spring Meeting Trial Reports
Once again, we will not be producing a paper meeting book.
Read more ....

2011 Spring Meeting of Participants
The Canadian Cancer Trials Group 2011 Spring Meeting of Participants will be held 29 April - 1 May at the Delta Chelsea Hotel in Toronto.
Read more ....

2011 Spring Meeting Event -- Cosbie Lecture
We are very pleased to announce Dr. Bernard Cummings as the 2011 "Cosbie Lecturer". The title of Dr. Cumming's talk is "Radiation Therapy, Rectal Cancer and Clinical Trials: Lessons and Opportunities."
Read more ....

Medidata Rave (EDC) Maintenance
Canadian Cancer Trials Group will be performing maintenance to its Electronic Data Capture (EDC) program, Medidata Rave. During this time there will be no access to the system, including patient enrollments.
Read more ....

Trial Management Group

Trial Activations
The Canadian Cancer Trials Group recently activated two trials -- Canadian Cancer Trials Group CRC.6 (CALGB 80702) and Canadian Cancer Trials Group IND.205.
Read more ....

BARL Holiday Closure
Please be advised that Bay Area Research Labs will be closed for the Easter Holiday.
Read more ....

Canadian Cancer Trials Group EN.7 (PORTEC 3)
The Canadian Cancer Trials Group EN.7 (PORTEC 3) Newsletter (No.7) is now available.
Read more ....

Trial Closed to Accrual
Canadian Cancer Trials Group IND.177 was recently closed to accrual.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

25 Mar 2011

General

Medidata Rave (EDC) Maintenance
Canadian Cancer Trials Group will be performing maintenance to its Electronic Data Capture (EDC) program, Medidata Rave (EDC). During this time there will be no access to the system, including patient enrollments.
Read more ....

Recent Publication
A publication related to Canadian Cancer Trials Group OV.17 (GINECO CALYPSO) was recently published online in the Annals of Oncology.
Read more ....

Highly Cited Cancer Papers, 2008-2010
In its most recent issue, the journal Nature Medicine has published lists of the most highly-cited primary research papers on cancer published between 2008 and 2010. Canadian Cancer Trials Group publications are included in each of the three years!!
Read more ....

US Cooperative Group Mergers
In separate announcements, several NCI-supported national cancer clinical trials cooperative groups declared their plans to merge.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

11 Mar 2011

Ethics Regulatory

Changes to Adverse Event Expedited Reporting System
The Cancer Therapy Evaluation Program (CTEP) has made changes to the Adverse Event Expedited Reporting System (AdEERS).
Read more ....

Finance and Operations

2011 Spring Meeting of Participants
The Canadian Cancer Trials Group 2011 Spring Meeting of Participants will be held 29 April - 1 May at the Delta Chelsea Hotel in Toronto.
Read more ....

General

Recent Publication
There was one recent publication related to Canadian Cancer Trials Group OV.16.
Read more ....

Trial Management Group

Trials Closed to Accrual
Two trials were recently closed to accrual -- Canadian Cancer Trials Group IND.190 and Canadian Cancer Trials Group MAC.5 (IBCSG 25-02).
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

25 Feb 2011

Ethics Regulatory

ER Updates
The Canadian Cancer Trials Group Ethics and Regulatory Group has updated its policies with respect to Initial Approval Requirements for Trials Not Under a CTA, and Annual Re-Approval Requirements.
Read more ....

General

Intergroup-Led Trials -- Primary Publications
The Canadian Cancer Trials Group has begun processes for identifying and locating primary publications for Intergroup-led trials, including BRC.1 (RTOG 0214), BR.13 (RTOG 93-09), SR.4 (SWOG 0033), and CE.2 (RTOG 94-02).
Read more ....

Recent Publications
There are two recent publications -- one related to LY.9, and the other discussing trends in methodology, results and interpretation of oncology trials closed early for benefit.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group CRC.3 (ECOG 5202)was closed to accrual on February 11, 2011.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

11 Feb 2011

Finance and Operations

2011 Spring Meeting of Participants
The Canadian Cancer Trials Group 2011 Spring Meeting of Participants will be held 29 April - 1 May at the Delta Chelsea Hotel in Toronto. Full-funded invitations were sent out, by email, today, 11 February 2011.
Read more ....

General

Recent Publications
There were two recent publications -- one reporting results from Canadian Cancer Trials Group MAP.2, and the other related to Canadian Cancer Trials Group MA.32.
Read more ....

Canadian Cancer Trials Group New Investigator Clinical Trials Course
The Canadian Cancer Trials Group is now accepting applications for its Biennial New Investigator Clinical Trials Course scheduled for August 9-12, 2011 at the Donald Gordon Centre in Kingston, Ontario.
Read more ....

Canadian Cancer Trials Group Publication Policy
The Canadian Cancer Trials Group is in the process of revising its publication policies. Dr. Ralph Meyer has outlined this process and the progress that has been made to date in revising this policy.
Read more ....

Trial Management Group

Drug Ordering for Trials/Agents Supplied by the PMB
The Pharmaceutical Management Branch (PMB) of CTEP is transitioning its drug order request system to an Online Agent Order Process (OAOP) effective immediately. While fax orders will continue to be accepted, on-line ordering will replace faxed-in ordering.
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CO.20 Closes to Accrual 4 Months Ahead of Projected!
Canadian Cancer Trials Group CO.20 is now closed to accrual having reached its accrual goal of 750 patients.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

28 Jan 2011

Finance and Operations

2011 Spring Meeting of Participants
The Canadian Cancer Trials Group 2011 Spring Meeting of Participants will be held 29 April - 1 May at the Delta Chelsea Hotel in Toronto.
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General

Single-Study Centres and DSMC Summary Reports
Just a reminder that trial-specific DSMC Summary Reports are now posted on trial websites. Single-study centres participating on these trials should download these reports and submit them to their Research Ethics Boards.
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Trial Management Group

Permanent Trial Closures
Following our annual Permanent Trial Closure Assessment, the Canadian Cancer Trials Group has identified those Canadian Cancer Trials Group-led trials and Intergroup-led trials that will be permanently closed.
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CRA Volunteer Opportunity
The Clinical Research Associates Steering Group (CRASG) is actively seeking a Clinical Research Associate (CRA) representative for the Brain and Sarcoma Site Committees.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

14 Jan 2011

Finance and Operations

2011 Spring Meeting of Participants
The Canadian Cancer Trials Group 2011 Spring Meeting of Participants will be held 29 April - 1 May at the Delta Chelsea Hotel in Toronto.
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General

Edith and Carla Eisenhauer Chair in Clinical Cancer Research
The Board of Trustees at Queen's University has recently re‐dedicated the Eisenhauer Research Chair, resulting in its new name: The Edith and Carla Eisenhauer Chair in Clinical Cancer Research.
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Ethics & Regulatory CRA Subcommittee -- REMINDER
To All CRAs -- The Ethics & Regulatory CRA Subcommittee is conducting a needs assessment survey to help it develop educational activities for Spring Meeting 2011.
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Recent Publications
There were 6 recent publications, including two reporting primary results of IND trials 149 and 173.
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Single-Study Centres and DSMC Summary Reports
Trial-specific DSMC Summary Reports are now posted on trial websites. Single-study centres participating on these trials should download these reports and submit them to their Research Ethics Boards.
Read more ....

Trial Management Group

Clinical Research Associates - Volunteer Opportunities
The US Cancer Trials Support Unit (CTSU) Site Advisory Panel is now beginning its fourth year and is seeking a representative from an Canadian Cancer Trials Group participating site.
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Distribution of IMP for Canadian Cancer Trials Group
The Canadian Cancer Trials Group has transitioned distribution of Investigational Medicinal Products (IMP) to Bay Area Research Logistics in Hamilton, Ontario.
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Trial Activation
The Canadian Cancer Trials Group is pleased to announce that HEC.1 (CALGB 80802) -- Phase III Intergroup Study of Sorafenib plus Doxorubicin versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma(HCC) -- was centrally activated 3 January 2011.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletins