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2010

Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

23 Dec 2010

Ethics Regulatory

Safety Reports Utility Changes
You can now enter an REB notification date into the Safety Reports Utility for reports for which REB submission is not mandated by Canadian Cancer Trials Group (those marked Not Req'd).
Read more ....

Ethics & Regulatory CRA Subcommittee
To All CRAs -- The Ethics & Regulatory CRA Subcommittee is conducting a needs assessment survey to help it develop educational activities for Spring Meeting 2011.
Read more ....

Finance and Operations

Bulletin in 2011
The first Bulletin of 2011 will be sent on Friday, January 14, 2011.
Read more ....

ECCO-AACR-EORTC-ESMO Workshop
The ECCO-AACR-EORTC-ESMO Workshop on Methods in Clinical Cancer Research is scheduled for 18-24 June 2011 in Flims, Switzerland, and is now accepting applications.
Read more ....

General

Canadian Cancer Trials Group Holiday Closure
The Canadian Cancer Trials Group Central Office will be closed with limited staff over the holidays beginning December 24, 2010. Please note that web-based applications (i.e. MANGO, GCP) will be available.
Read more ....

US Institute of Medicine Report
In April, the US Institute of Medicine (IOM) issued a report regarding the current state and future of the NCI/CTEP Clinical Trials Cooperative Group Program. The NCI/CTEP is now beginning to respond to this report.
Read more ....

Happy Holidays and Happy New Year!!!!
On behalf of everyone at Canadian Cancer Trials Group's Central Office, we would like to wish everyone a very Merry Christmas, Happy Holidays, and Happy New Year. All the best for a restful and peaceful holiday season.
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Recent Publications
There were two recent publications, including one reporting the final results for Canadian Cancer Trials Group REC.1 (CALGB 90206).
Read more ....

Scott Sawler -- ER Manager
It is with very mixed emotions that we inform you that Scott Sawler will be leaving the Canadian Cancer Trials Group to take on an exciting new position as Director General for the Natural Health Products Directorate of Health Canada.
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Cooperative Group Holiday Closures
We are currently collecting and collating cooperative groups' holiday closures. This information is posted on the Canadian Cancer Trials Group website at http://www.ctg.queensu.ca.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

10 Dec 2010

Finance and Operations

Next Canadian Cancer Trials Group Bulletin
The next edition of the Bulletin will be sent on Thursday, 23 December 2010.
Read more ....

General

Canadian Cancer Trials Group Holiday Closure
The Canadian Cancer Trials Group Central Office will be closed with limited staff over the holidays beginning December 24, 2010. Please note that web-based applications (i.e. MANGO, GCP) will be available.
Read more ....

Cooperative Group Holiday Closures
We are currently collecting and collating cooperative groups' holiday closures. This information is posted on the Canadian Cancer Trials Group website at http://www.ctg.queensu.ca.
Read more ....

San Antonio Breast Cancer Symposium
Several Canadian Cancer Trials Group abstracts are being presented at the 33rd Annual San Antonio Breast Cancer Symposium being held December 8-12, 2010 in San Antonio, Texas.
Read more ....

Career Opportunity at Canadian Cancer Trials Group
The Canadian Cancer Trials Group currently has an opening for a Study Coordinator position.
Read more ....

Canadian Cancer Trials Group MA.27
Final results of Canadian Cancer Trials Group MA.27 -- A Randomized Phase III Trial of Exemestane versus Anastrozole in Postmenopausal Women with Receptor Positive Primary Breast Cancer -- were presented at the San Antonio Breast Cancer Symposium on Thursday, 9 December, 2010
Read more ....

2011 New Investigator Clinical Trials Course
SAVE THE DATE -- The 2011 Canadian Cancer Trials Group New Investigator Clinical Trials Course will be held 9-12 August 2011 in Kingston, Ontario.
Read more ....

Trial Management Group

Shipment of Specimens
Specimens that are collected and banked at the Canadian Cancer Trials Group Tumour Bank SHOULD NOT be shipped between December 16, 2010 and January 2, 2011 inclusive.
Read more ....

Trial Activation
We are happy announce the central activation of IND.204 -- A Phase II Study of PX-866 in Patients with Glioblastoma Multiforme at Time of First Relapse or Progression.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

26 Nov 2010

Ethics Regulatory

Roster Reminders
To ensure centres do not experience delays when randomizing patients or accessing specific Canadian Cancer Trials Group resources (e.g. safety reports) over the Christmas holidays, rostering staff have several recommendations.
Read more ....

General

American Society of Hematology (ASH) Annual Meeting
Several Canadian Cancer Trials Group abstracts will be presented at the 52nd ASH Annual Meeting and Exposition being held December 4-7, 2010 in Orlando, Florida.
Read more ....

Recent Publication
A recent article -- Plasma transforming growth factor α and amphiregulin protein levels in Canadian Cancer Trials Group BR.21 -- was published in the Journal of Clinical Oncology.
Read more ....

Trial Management Group

IMP Distributor Holiday Shutdown
Please be advised that Canadian Cancer Trials Group's drug distribution partner, Bay Area Research Logistics, will be closed December 24th - January 2nd.
Read more ....

Trial Activation
SC.23 -- A Randomized Phase III Double-Blind Study of Dexamethasone versus Placebo in the Prophylaxis of Radiation-Induced Pain Flare following Palliative Radiotherapy for Bone Metastases -- has been centrally activated.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

12 Nov 2010

General

Maria Ricci Memorial Lectureship in Medical Oncology
Dr. Kathy Pritchard is this year's guest speaker for the Maria Ricci Memorial Lectureship in Medical Oncology being held 15 November 2010 at the Cancer Research Institute, Queen's University.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

29 Oct 2010

Finance and Operations

Special Fall Meeting 2010
The Canadian Cancer Trials Group is replacing its standard fall meeting format with a special meeting of the Disease Site Chairs and the Clinical Trials Committee scheduled for 4-5 November 2010.
Read more ....

General

Maria Ricci Memorial Lectureship in Medical Oncology
Dr. Kathy Pritchard is this year's guest speaker for the Maria Ricci Memorial Lectureship in Medical Oncology being held 15 November 2010 at the Cancer Research Institute, Queen's University.
Read more ....

Recent Article Related to Canadian Cancer Trials Group CO.17
A recent article published in JAMA using patients from Canadian Cancer Trials Group's CO.17 trial has found that cetuximab use was associated with longer OS and PFS among patients with chemotherapy-refractory colorectal cancer with p.G13D-mutated tumours.
Read more ....

Trial Management Group

Investigational Medicinal Product (IMP)
Drug distribution for some Canadian Cancer Trials Group trials is being transitioned to other vendors over the next 1-3 months.
Read more ....

Trial Closed to Accrual
Canadian Cancer Trials Group ME.10 was closed to accrual effective Tuesday, October 26, 2010.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

15 Oct 2010

Ethics Regulatory

Important Changes to Canadian Cancer Trials Group's Ethics Requirements
ERG has updated our ethics website to contain comprehensive information regarding our policies on initial approval, trial modifications, trial websites, documentation requirements, safety reporting to the REB and more.
Read more ....

Changes to the Ethics Research Associate Centre Assignments
Due to staffing changes in ERG, some centres' ethics research contact will change effective October 15th, 2010.
Read more ....

General

Maria Ricci Memorial Lectureship in Medical Oncology
Dr. Kathy Pritchard is this year's guest speaker for the Maria Ricci Memorial Lectureship in Medical Oncology being held 15 November 2010 at the Cancer Research Institute, Queen's University.
Read more ....

Recent Publication and Press Release
The primary results of Canadian Cancer Trials Group OV.16 were recently published in the Journal of the National Cancer Institute and was selected by the Journal to be highlighted to the media.
Read more ....

Trial Management Group

Canadian Appendix for Intergroup Trials
To facilitate centre participation on Intergroup trials (Canadian Cancer Trials Group trials that are led by other cooperative groups), we have created a stand alone document called the "Canadian Appendix".
Read more ....

Trial Closed to Accrual
One trial -- MAC.12 -- was recently closed to accrual.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

01 Oct 2010

Audit Monitoring Group

Requirements for Satellite Pharmacies
We would like to remind all pharmacists and centre personnel that any location outside the main pharmacy where a multiple day supply of study drug is stored prior to dispensation is considered a satellite pharmacy.
Read more ....

General

Two Recent Publications
One is related to OV.13. The other reports results of a genome-wide association sub-study of Canadian Cancer Trials Group MA.27 that was recently published online in the Journal of Clinical Oncology.
Read more ....

Trial Management Group

Trial Activation
Canadian Cancer Trials Group's first pediatric oncology clinical trial -- IND.203 -- was activated on 21 September 2010.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

17 Sep 2010

Ethics Regulatory

Reminder - Call for volunteers for the CRAER Subcommittee
The Ethics and Regulatory Group invites your application to the CRA Ethics and Regulatory Subcommittee. Applications will be accepted for one more week and should be received at Central Office by the end of the day on Friday, September 24th.
Read more ....

CTCAE v4.0 Booklets
CTCAE v4.0 booklets are available only by download from CTEP's website.
Read more ....

Changes in Safety Policy
Canadian Cancer Trials Group is pleased to announce revisions to our safety reporting process and requirements for participating centre submissions (effective 20 September 2010).
Read more ....

Consent Form Review Policy
Effective 27 September 2010, Canadian Cancer Trials Group will be reviewing local consent forms to ensure that they are in compliance with Canadian Cancer Trials Group SOPs only, particularly regarding compensation, drug supply and access to participant/potential participant records.
Read more ....

General

Recent Publication
Final results of Canadian Cancer Trials Group PA.2 (ESPAC-3) -- Phase III Adjuvant Trial In Pancreatic Cancer Comparing (1) 5FU And D-L Folinic Acid Vs (2) Gemcitabine Vs (3) No Adjuvant Treatment -- were recently published in the Journal of the American Medical Association.
Read more ....

Recent Publication
A recent study published in JCO has advanced findings of the Canadian Cancer Trials Group BR.10 trial.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group IND.183 -- A Phase II Study of Sunitinib in Patients with Advanced Malignant Pleural Mesothelioma -- was closed to accrual on 10 September 2010.
Read more ....

Two Other Recent Publications
There were two other recent publications, including one related to Canadian Cancer Trials Group PA.3.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

03 Sep 2010

Ethics Regulatory

Update to the Web-Based Ethics Utility
The web-based ethics utility has been updated to allow CCRAs to have access to reports on trials in which their centre is participating.
Read more ....

Call for Volunteers for the CRA ER Subcommittee
The Ethics and Regulatory Group invites your application to the CRA Ethics and Regulatory Subcommittee. Applications should be received at Central Office by the end of the day on Friday, September 24th.
Read more ....

CTCAE v4.0 Booklets
CTCAE v4.0 booklets are now available.
Read more ....

Finance and Operations

What's in a Name?
The Canadian Cancer Trials Group is looking for a new name.
Read more ....

General

Recent Publications
There were four recent publications, including primary results for two Canadian Cancer Trials Group trials -- IND.165 and OV.13.
Read more ....

Holiday Office Closure
The Canadian Cancer Trials Group will be closed on Monday, September 6, 2010 for Labour Day. Regular business hours will resume on Tuesday, September 7 at 8:00 a.m. EDT.
Read more ....

NCI's Cooperative Groups National Meeting Report
Twice per year, the US Cancer Therapy Evaluation Program produces a report highlighting all of the Cooperative Groups' research in progress. The Canadian Cancer Trials Group contributes to this report by submitting information related to all of our CTEP-affiliated trials.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group REC.2 (ECOG E2805) -- ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma -- has been closed to accrual.
Read more ....

GI Site Committee Activities
A memo outlining the ongoing opportunities and initiatives of Canadian Cancer Trials Group's Gastrointestinal Site Committee is available.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

20 Aug 2010

General

Dr. Kim Chi New Chair of IND Committee
Dr. Kim Chi has officially taken over as Chair of the Canadian Cancer Trials Group's Investigational New Drug Committee. Dr. Hal Hirte, after 2 years at the helm, now moves to the position of Past Chair.
Read more ....

Recent Publication
The primary results of IND.185 -- A Phase II Study of Sunitinib in Patients with Recurrent Epithelial Ovarian and Primary Peritoneal Carcinoma -- was recently published in Annals of Oncology.
Read more ....

Trial Management Group

MA.32 Enrolls First Patient
The first patient has been enrolled on Canadian Cancer Trials Group MA.32 -- a trial investigating whether metformin, by lowering insulin levels, reduces breast cancer recurrences in women with newly-diagnosed breast cancer.
Read more ....

Trial Closed to Accrual
Canadian Cancer Trials Group IND.192 was recently closed.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

06 Aug 2010

Finance and Operations

Upcoming Spring Meetings
Please mark your calendars for our Spring Meeting of Participants future dates and location.
Read more ....

General

Dr. Eisenhauer Receives Prestigious GOC Award
Elizabeth Eisenhauer was recently recognized by the Society of Gynecologic Oncology of Canada (GOC) for her outstanding contributions to gynecologic oncology in Canada and abroad.
Read more ....

Trial Management Group

Trial Activation
One trial -- CEC.2 -- was recently activated.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

23 Jul 2010

General

Holiday Office Closure
Monday, August 2, 2010 is a Civic Holiday (in Canada), and the Canadian Cancer Trials Group will be closed. MANGO Patient Allocation System will be available. Regular business hours will resume on Tuesday, August 3 at 8:00 a.m. EDT.
Read more ....

Confidentiality of Canadian Cancer Trials Group Materials
Central Office recently received a request for confidential information from an outside agency. In view of this, we wanted to emphasize to our members the importance of Canadian Cancer Trials Group's confidentiality policy.
Read more ....

Recent Publication
There was one recent publication related to Canadian Cancer Trials Group CO.17.
Read more ....

Trial Management Group

Shortage of Commercially-Available Cytarabine
It has recently come to Canadian Cancer Trials Group's attention that certain centres participating in trials ALC.1, ALC.2, AL.5 & LY.12 may be experiencing a shortage in the commercial supply of cytarabine of unknown duration.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

09 Jul 2010

Finance and Operations

Spring Meeting 2010 Expense Claim Forms
Please note the deadline for submission of expense claim forms for Spring Meeting 2010 has passed.
Read more ....

General

Recent Publications
There were two recent publications, both discussing aspects of quality of life.
Read more ....

Trial Management Group

Trial Activation
One trial, Canadian Cancer Trials Group IND.202, was recently activated.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

25 Jun 2010

Ethics Regulatory

Maria Smith - New Email Contact at Canadian Cancer Trials Group
We have created a new email contact to prevent emails from our webadmin account (e.g. for password requests and services covered by the CV and roster accounts) from being caught up in your spam filters.
Read more ....

Finance and Operations

2010 Spring Meeting Expense Claims
Please note the deadline for submission of Expense Claim Forms for those who received a full- or partial-supported invitation to the 2010 Spring Meeting is 30 June 2010.
Read more ....

General

Canadian Cancer Trials Group Holiday Office Closure
The Canadian Cancer Trials Group will be closed on Thursday, July 1, 2010 in observance of Canada Day. Regular business hours will resume on Friday, July 2 at 8:00 a.m. EDT.
Read more ....

Putting Evidence-Based Policy into Practice Survey REMINDER
REMINDER -- PLEASE COMPLETE THIS SURVEY. On behalf of Drs Elizabeth Eisenhauer and Terrence Sullivan, we invite your participation in a survey to help inform a session being held at the 2010 NCRI Conference "Putting Evidence-Based Policy into Practice".
Read more ....

Trial Management Group

Trial Activation
Two trials -- IND.191 and MA.32 -- were recently activated.
Read more ....

Canadian Cancer Trials Group's CRA Steering Group
The Canadian Cancer Trials Group's CRA Steering Group (CRASG) has posted a memo which provides an overview of the current status of the Canadian Cancer Trials Group CRA Committee, and outlines the educational strategies the CRASG will be implementing.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

11 Jun 2010

Ethics Regulatory

Web-Based Ethics Utility
There have been a number of requests for clarification regarding aspects of the ethics utility.
Read more ....

General

Canadian Cancer Trials Group IND Program Expands to Include Pediatrics
The Canadian Cancer Trials Group Investigational New Drug Program plans to extend its drug development program to include the pediatric population.
Read more ....

Bulletin Has A New Format!
You may have noticed the Bulletin has a new format. Hopefully, this new format will help you navigate through the items more easily.
Read more ....

ASCO 2010 Highlights
Interim results of the Canadian Cancer Trials Group's PR.3 study combining radiation and hormone therapy in patients with high risk prostate cancer show it significantly improves the likelihood of patients living longer. The results were recently presented at ASCO.
Read more ....

Operations

2010 Spring Meeting Expense Claims
If you received a full- or partial-funded invitation to the Spring Meeting of Participants 2010, please read carefully.
Read more ....

Trial Management Group

Trial Activation
One trial ... IND.198 ... was recently activated.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

28 May 2010

General

Recent Publications
There were two recent publications -- an article describing primary results of OV.17, and the other related to CO.3.
Read more ....

Putting Evidence-Based Policy into Practice Survey
PLEASE COMPLETE THIS SURVEY. On behalf of Drs Elizabeth Eisenhauer and Terrence Sullivan, we invite your participation in a survey to help inform a session being held at the 2010 NCRI Conference "Putting Evidence-Based Policy into Practice".
Read more ....

ASCO 2010 Highlights
The Canadian Cancer Trials Group is presenting results from several trials at the American Society of Clinical Oncology Annual Meeting in Chicago, IL, June 4-8, 2010.
Read more ....

Memorial Day Holiday (US) Closures
Many cooperative group offices in the United States will be closed Monday, May 31, 2010 for the Memorial Day Holiday.
Read more ....

Operations

2010 Spring Meeting Expense Claims
If you received a full- or partial-funded invitation to the Spring Meeting of Participants 2010, please read the following carefully.
Read more ....

Trial Management Group

Trial Activation
One trial -- IND.197 -- was recently activated.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

14 May 2010

Ethics Regulatory

CTCAE v4.0 Booklets
Common Terminology Criteria for Adverse Events (CTCAE) v4.0 booklets will be available this Summer/Fall.
Read more ....

Annual Re-Approval Requirements for NCI US-Affiliated Trials
Full board annual approval is required while the trial is open to accrual, and while patients at the centre in question are undergoing protocol treatment or protocol-mandated interventions, including quality of life questionnaires.
Read more ....

General

Recent Publications
There were two recent publications -- one related to Canadian Cancer Trials Group BR.24, and the other related to Canadian Cancer Trials Group LY.7.
Read more ....

Single-Study Centres and DSMC Summary Reports
Trial-specific DSMC Summary Reports are now posted on trial websites. Single-study centres participating on these trials should download these reports and submit them to their Research Ethics Boards.
Read more ....

Operations

2010 Spring Meeting Expense Claims
If you received a full- or partial-funded invitation to the Spring Meeting of Participants 2010, please read carefully.
Read more ....

Trial Management Group

Trials Closed to Accrual
Three trials were recently closed to accrual -- MAC.4, MAC.4C, and SR.5.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

30 April 2010

General

2010 Spring Meeting Event -- Cosbie Lecture
We are very pleased to announce Dr. Hartley Stern as the 2010 "Cosbie Lecturer". The title of Dr. Stern's talk is '5 Year Survival of Clinical Cancer Trials in Canada: Perspective of a Lapsed Investigator'.
Read more ....

2010 Spring Meeting -- REMINDERS
The Canadian Cancer Trials Group 2010 Spring Meeting of Participants is being held 30 April - 2 May at the Fairmont Queen Elizabeth Hotel in Montreal.
Read more ....

2010 Spring Meeting Expense Claims
Please submit your 2010 Spring Meeting expense claim within 10 days of the meeting and by 30 June 2010 at the latest.
Read more ....

2010 Spring Meeting Trial Reports -- Reminder
Spring Meeting 2010 Trial Reports are available on the Canadian Cancer Trials Group members-only website.
Read more ....

Trial Management Group

Permanent Trial Closure
Canadian Cancer Trials Group MA.14 was permanently closed on Friday, April 23, 2010.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

16 April 2010

Ethics Regulatory

Web-Based Ethics Utility and Ethics Reminders
The web-based ethics utility has been updated. Changes include the addition of colour coding to indicate items that are coming due or overdue, and re-arranging the layout for ease of use.
Read more ....

Have You Changed Your Name?
Please let us know! It's a very simple process!
Read more ....

Participants List & Participants List Change Form
We wanted to remind centre staff about the processes for completing Canadian Cancer Trials Group Participants Lists and Participants List Change Forms.
Read more ....

General

Spring Meeting of Participants Event -- Cosbie Lecture
We are very pleased to announce Dr. Hartley Stern as the 2010 "Cosbie Lecturer". The title of Dr. Stern's talk is '5 Year Survival of Clinical Cancer Trials in Canada: Perspective of a Lapsed Investigator'.
Read more ....

Recent Publications
There were two recent publications -- one a correlative analysis using data from IND.126, IND.148, IND.160, and EN.5; and the other using data from BR.10, BR.14 and BR.18.
Read more ....

2010 Spring Meeting -- REMINDERS
The Canadian Cancer Trials Group 2010 Spring Meeting of Participants is being held 30 April - 2 May at the Fairmont Queen Elizabeth Hotel in Montreal.
Read more ....

Spring Meeting Hotel Accommodation -- Reminder
If you have not yet done so, please make your hotel reservation TODAY.
Read more ....

Spring Meeting Trial Reports
2010 Spring Meeting Trial Reports will be posted by end of the day Monday, 19 April.
Read more ....

Trial Management Group

Reminders -- Supporting Documentation and Data Queries
Centre staff are reminded that only protocol-mandated supporting documents should be forwarded to Central Office, and that centres should complete all requested information before returning data queries.
Read more ....

Clinical Investigator Policy for IND Studies
Centres are reminded that only faculty-level/ clinical staff can be accepted as investigators able to enroll patients on IND trials that utilize investigational agents.
Read more ....

Case Report Form Signature Policy
Following a review of applicable regulations, we will be implementing a change to our Case Report Form signature policy.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

01 April 2010

Ethics Regulatory

Quarterly Ethics Reminders
Effective immediately, Quarterly Ethics Reminders will no longer be sent out via e-mail.
Read more ....

General

MA.17 Accomplishments
Recently, centres were informed that there is no longer a requirement to follow MA.17 patients who were not entered on MA.17R. Additionally, those centres that were not activated on MA.17R were also informed that they should permanently close the trial.
Read more ....

Information for New Centre Personnel
Some general information for new centre personnel related to passwords, website access and other information is posted to the Canadian Cancer Trials Group website.
Read more ....

Recent Publications
There were three recent publications relating to the design and conduct of phase I and II clinical trials of new therapeutics and anticancer agents; and another publication related to BR.10.
Read more ....

Spring Meeting of Participants Event -- Cosbie Lecture
We are very pleased to announce Dr. Hartley Stern as the 2010 "Cosbie Lecturer". The Cosbie Lecture is scheduled for Saturday, 1 May 2010 at 11:15 am at the Fairmont Queen Elizabeth Hotel in Montreal.
Read more ....

2010 Spring Meeting of Participants
The Canadian Cancer Trials Group 2010 Spring Meeting of Participants will be held 30 April - 2 May at the Fairmont Queen Elizabeth Hotel in Montreal.
Read more ....

Holiday Closure
The Canadian Cancer Trials Group will be closed on Friday, April 2, 2010 in observance of Good Friday. Regular business hours will resume on Monday, April 5 at 8:00 am EDT.
Read more ....

Trial Management Group

Trial Activation
One trial -- IND.200 -- was recently activated.
Read more ....

Trials Closed to Accrual
Three trials were recently closed -- MAP.3, CE.5 and MA.29.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

19 March 2010

General

Quality of Life Committee
The Canadian Cancer Trials Group Quality of Life Committee is currently seeking up to 2 new members.
Read more ....

Next Bulletin
The next Canadian Cancer Trials Group Bulletin will be sent on Thursday, April 1. The Bulletin's regular schedule will resume on Friday, April 16.
Read more ....

Holiday Closure
The Canadian Cancer Trials Group will be closed on Friday, April 2, 2010 for Good Friday. Regular business hours will resume on Monday, April 5 at 8:00 am EDT.
Read more ....

Spring Meeting Invitations
Full-funded and partial-funded invitations have been sent to all Canadian Cancer Trials Group members who are eligible for funding.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group IND.188 was recently closed to accrual.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

05 March 2010

General

2010 Spring Meeting
It is necessary to reduce the overall costs associated with our Annual Spring Meeting and, as a result, a reduced number of funded invitations will be offered and a process to institute partial funding will be implemented.
Read more ....

2010 Spring Meeting Invitations
Spring Meeting invitations will be sent next week.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

19 February 2010

General

Canadian Cancer Trials Group Servers Briefly Unavailable
The Canadian Cancer Trials Group servers will be unavailable for randomization this Saturday, February 20, 2010, from 07:00 - 10:00 EST. We are sorry for any inconvenience this may cause.
Read more ....

Recent Publications
There were three recent publications -- one related to BR.10, one related to BR.21, and the primary publication for IND.141.
Read more ....

Trial Management Group

*NEW* RECIST 1.1 Tumour Measurement Worksheet
A RECIST 1.1 Tumour Measurement Form has been created and is available to CRAs on the external site.
Read more ....

Trial Activation
One trial -- IND.195 -- was recently activated.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

05 February 2010

General

Canadian Cancer Trials Group Holiday Closure
The Canadian Cancer Trials Group will be closed on Monday, February 15, 2010 to celebrate Family Day. Regular business hours will resume on Tuesday, February 16 at 8:00 am EST.
Read more ....

Curriculum Vitae (CV) Collection
The Canadian Cancer Trials Group will now begin collecting updated CVs from approved investigators every 2 years.
Read more ....

NCI Neuroendocrine Tumour Task Force
The Canadian Cancer Trials Group wishes to thank Dr. Lillian Siu for her leadership as she steps down as Chair of the NCI Neuroendocrine Tumour Task Force.
Read more ....

Trial Management Group

Trial Closed to Accrual
Canadian Cancer Trials Group MAC.9/SWOG S0307 -- Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer -- was closed to accrual February 1, 2010.
Read more ....

Permanent Trial Closure Search Utility
The Canadian Cancer Trials Group has created a web-based search utility for trials that have now been permanently closed.
Read more ....

If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

22 January 2010

Ethics Regulatory

Ethics Research Associates
The Ethics and Regulatory Group would like to remind you that the new assignment of Ethics Research Associates will come into effect on 1 February 2010.
Read more ....

General

Recent Publication
There was one recent publication related to Canadian Cancer Trials Group AL.2 (INT0129.
Read more ....

Clinical Trials Committee
During the Fall 2009 Clinical Trials Committee Teleconference, one trial was approved for activation.
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Single-Study Centres and DSMC Summary Reports -- REMINDER
Trial-specific DSMC Summary Reports are now posted on trial websites. Single-study centres participating on these trials should download these reports and submit them to their REBs.
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Trial Management Group

Permanent Closure of Intergroup-Led Trials
We have now completed the annual Permanent Closure assessment for Intergroup-led trials.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletin

Canadian Cancer Trials Group Bulletin

A bi-weekly Bulletin to notify participants at member centres of recent activities at Central Office, including summaries of recent trial activations/closures, upcoming meeting information, office closures, press releases, etc.

08 January 2010

Ethics Regulatory

Ethics Research Associates
The Ethics and Regulatory Group is excited to announce a new approach to the way we assign Ethics Research Associates to trials.
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General

Recent Publications
There were 3 recent publications - the primary results for MA.9, an addendum to CADTH Guidelines, and discussion of the association between DFS and OS in colon cancer patients when survival is prolonged after recurrence.
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SWOG -- Due Dates for Baseline Forms
The SWOG Data Operations Centre is making a change regarding the due dates for baseline forms that are posted at the time of registration. As of 1 January 2010, this requirement will change from 14 days to 7 days.
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SWOG Operations Office Is Moving
The Southwest Oncology Group Operations Office has moved effective January 4, 2010.
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BR.10 Accomplishments
Following our annual Permanent Trial Closure Assessment, BR.10 has been permanently closed. BR.10 is an outstanding example of an Canadian Cancer Trials Group-led trial that has had extraordinary implications for health care delivery on an international level.
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Single-Study Centres and DSMC Summary Reports
Trial-specific DSMC Summary Reports are now posted on trial websites. Single-study centres participating on these trials should download these reports and submit them to their Research Ethics Boards.
Read more ....

Trial Management Group

Permanent Trial Closure
Following our annual Permanent Trial Closure Assessment, a number of additional Canadian Cancer Trials Group-led trials have been permanently closed.
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Trials Closed to Accrual
Canadian Cancer Trials Group CXC.1 / GOG 0219 and Canadian Cancer Trials Group HD.8 / EORTC 20012 are now closed to accrual.
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If you have any questions, comments or suggestions, please contact Canadian Cancer Trials Group Bulletin


Canadian Cancer Trials Group Bulletins