Canadian Cancer Trials Group Bulletins

Trial Management Group

RIPPLE Reminder!!

Friday, May 16, 2014 is the deadline for submission of MA.32 paper PLCFs and pre-version 8 paper PLs/PLCFs for all other trials at the Canadian Cancer Trials Group Central Operations and Statistics Office! After this date, any paper MA.32 PLCFs that are submitted will be returned and all changes to the MA.32 participants list must be made in the RIPPLE system (including all PL additions and removals and QI approvals).

In addition, May 16, 2014 is also the last day that paper PLs/PLCFs that are NOT version 8 will be accepted (all applicable trial websites were updated with version 8 PLs/PLCFs on April 28). After this date, paper PLs/PLCFs that are submitted using previous versions will not be accepted and new version 8 PLs/PLCFs will be required.

Thank you to all centres for your assistance and your feedback with the RIPPLE system since its implementation on April 28, 2014.

If you have any questions about the RIPPLE system, please do not hesitate to email us at If you have general questions regarding PLs/PLCFs, please do not hesitate to email

Thank you,
The RIPPLE team