Canadian Cancer Trials Group Bulletins

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Recent Publication

SC.20: A Phase III International Randomized Trial of Single Versus Multiple Fractions for Re-Irradiation of Painful Bone Metastases

The purpose of this study was to establish a survival prediction model in the setting of a randomized trial of re-irradiation for painful bone metastases. The authors conclude that this survival prediction model will assist in choosing dose fractionation and they recommend a single 8 Gy in the worst group identified.

Chow E, Ding K, Parulekar WR, Wong RKS, van der Linden YM, Roos D, Hartsell WF, Hoskin P, Wu JSY, Nabid A, Leer JW, Vonk E, Babington S, Demas WF, Wilson CF, Brundage M, Zhu L, Meyer RM. Predictive model for survival in patients having repeat radiation treatment for painful bone metastases (ONLINE). Radiotherapy and Oncology 2015.

http://www.thegreenjournal.com/article/S0167-8140%2815%2900567-8/fulltext