NCIC Clinical Trials Group

Brain Gastro-Intestinal Gynecologic Hematologic Lung Sarcoma
Breast Genito-Urinary Head & Neck IND Melanoma Symptom Control

Spring Meeting Trial Reports: 2011 / 2010 / 2009
ID Study Title Status
IND.173 A Phase I/II Study of AZD0530 in Combination with Gemcitabine in Patients with Advanced Pancreatic Cancer    MORE... Permanently Closed
IND.187 A Phase I Study Of AZD2281 In Combination With Irinotecan In Patients With Locally Advanced or Metastatic Incurable Colorectal Cancer    MORE... On Hold
BI.1 Phase III Trial Of Combined Gemcitabine Plus Capecitabine Chemotherapy Versus Gemcitabine Alone In Advanced Biliary Cancer    MORE... Permanently Closed
CO.13
NCCTG 9741
A Randomized Phase III Trial of Combinations of Oxaliplatin (OXAL), 5-fluorouracil (5-FU), and Irinotecan (CPT-11) as Initial Treatment of Patients with Advanced Adenocarcinoma of the Colon and Rectum    MORE... Closed
CO.14
CALGB 9581
Phase III Randomized Study of Adjuvant Immunotherapy with Monoclonal Antibody 17-1A versus No Adjuvant Therapy Following Resection for Stage II (Modified Astler-Coller B2) Adenocarcinoma of the Colon    MORE... Permanently Closed
CO.16
MRC CR07
A Medical Research Council Colorectal Cancer Working Party Randomized Trial Comparing Pre-Operative Radiotherapy and Selective Post-Operative Chemoradiotherapy in Rectal Cancer    MORE... Closed
CO.17 A Phase III Randomized Study of Cetuximab (Erbitux TM, C225) and Best Supportive Care versus Best Supportive Care in Patients with Pretreated Metastatic Epidermal Growth Factor Receptor (EGFR) - Positive Colorectal Carcinoma    MORE... Permanently Closed
CO.20 A Phase III Randomized Study of Brivanib Alaninate (BMS-582664) in Combination with Cetuximab (Erbitux) Versus Placebo in Combination with Cetuximab (Erbitux) in Patients With K-Ras Wild Type Tumours Previously Treated With Combination Chemotherapy for Metastatic Colorectal Carcinoma    MORE... Closed
CO.21 A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients with High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (Challenge)    MORE... Open
CRC.2
NCCTG 0147
A Randomized Phase III Trial of Oxaliplatin (OXAL) Plus 5-Fluouracil (5-FU)/Leucovorin (CF) with or without Cetuximab (C225) after Curative Resection for Patients with Stage III Colon Cancer    MORE... Closed
CRC.3
ECOG 5202
A Randomized Phase III Study Comparing 5-FU, Leucovorin and Oxaliplatin versus 5-FU, Leucovorin, Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers    MORE... Closed
CRC.4
ECOG 5204
Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil and Leucovorin vs Oxaliplatin, 5-Fluorouracil, Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-Operative Chemoradiation    MORE... Closed
CRC.5
CALGB 80405
A Phase III Trial of Irinotecan/5-Fu/Leucovorin or Oxaliplatin/5-Fu/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum    MORE... Open
CRC.6
CALGB 80702
A Phase III Trial of 6 versus 12 Treatments of Adjuvant Folfox Plus Celecoxib or Placebo For Patients With Resected Stage III Colon Cancer    MORE... Open
ES.2
TROG 0301
A Randomized Phase III Study in Advanced Oesophageal Cancer to Compare Quality of Life and Palliation of Dysphagia in Patients Treated with Radiotherapy versus Chemo-Radiotherapy    MORE... Open
GAC.1
CALGB 80101
Phase III Randomized Study of Adjuvant Chemoradiation After Resection in Patients with Gastric or Gastroesophageal Adenocarcinoma    MORE... Closed
HEC.1
CALGB 80802
Phase III Randomized Study of Sorafenib Plus Doxorubicin Versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC)    MORE... Open
NEC.2
CALGB 80701
Randomized Phase II Study of Everlimus Alone versus Everolimus Plus Bevacizumab in Patients with Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumours    MORE... Open
PA.2
ESPAC
ESPAC-3 (v2)
Phase III Adjuvant Trial in Pancreatic Cancer Comparing (1) 5FU and D-L Folinic Acid vs (2) Gemcitabine vs (3) No Adjuvant Treatment    MORE... Closed
PA.3 A Randomized Placebo Controlled Study of OSI-774 plus Gemcitabine in Patients with Locally Advanced, Unresectable or Metastatic Pancreatic Cancer    MORE... Permanently Closed
PAC.1
SWOG 0205
A Phase III Randomized Open-Label Study Comparing Gemcitabine plus Cetuximab (IMC-225) versus Gemcitabine as First Line Therapy of Patients with Advanced Pancreas Cancer    MORE... Permanently Closed
PAC.2
ECOG 4201
A Randomized Phase III Study of Gemcitabine in Combination with Radiation Therapy versus Gemcitabine Alone in Patients with Localized, Unresectable Pancreatic Cancer    MORE... Permanently Closed

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