2012

NCIC CTG Bulletin

11 May 2012

General

Trial Activation
One trial -- IND.208: A Phase I/II Study of the PI3 Kinase Inhibitor BKM120 Given in Combination with Panitumumab in Patients with Metastatic or Advanced Ras Wild-type Colorectal Cancer -- was recently activated.
Read more ....

NCIC CTG Holiday Closure
The NCIC Clinical Trials Group will be closed on Monday, May 21, 2012 to celebrate Victoria Day. Regular business hours will resume on Tuesday, May 22 at 8:00 am EDT.
Read more ....

Recent Publications
There were two recent publications, including one reporting the primary results of NCIC CTG OV.14 (NSGO OC9804).
Read more ....

NCIC CTG Spring Meeting: Claiming CME Credits
The 2012 Annual Spring Meeting of Participants is an Accredited Group Learning Activity (Section 1) of the Royal College of Physicians and Surgeons of Canada. Meeting participants may be eligible to receive CME credits.
Read more ....

Spring Meeting 2012 Expense Claim Forms
When sending in your Spring Meeting 2012 Expense Claim Form, please be sure to read the Travel Policy carefully to help ensure your claims are processed as quickly and efficiently as possible. Incomplete or inadequate claims will be returned.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

26 Apr 2012

General

2012 Spring Meeting Event -- Cosbie Lecture
We are very pleased to announce Dr. Robert Califf as the 2012 "Cosbie Lecturer". The title of Dr. Califf's talk is "The American Clinical Trials Enterprise: Are We Reaching the Tipping Point for Transformation?"
Read more ....

2012 Spring Meeting Trial Reports
The 2012 Spring Meeting Trial Reports are now available on the NCIC CTG members-only website using this link ... http://www.ctg.queensu.ca/trials/.
Read more ....

Recent Publication
The primary report for NCIC CTG CRC.2 (NCCTG N0147) was recently published in the Journal of the American Medical Association.
Read more ....

Office of Compliance and Oversight

Office of Compliance and Oversight (OCO) - New Website
OCO is pleased to announce the release of its updated website. All content related to Audit, Monitoring, Ethics, Safety, and the Centre Performance Index (CPI), as well as associated Forms and Resources and News is available through the new website.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

13 Apr 2012

General

2012 Spring Meeting of Participants -- Wireless Internet
For 2012, we have arranged for free wireless internet to be available in the meeting rooms and in Churchill Court of the Delta Chelsea Hotel. Access will be available to all participants for the duration of Spring Meeting beginning Friday, 27 April 2012.
Read more ....

2012 Spring Meeting Trial Reports
The 2012 Spring Meeting Trial Reports will be available by Tuesday, April 17 on the NCIC CTG members-only website using this link ... http://www.ctg.queensu.ca/trials/.
Read more ....

2012 Spring Meeting of Participants -- Registration
On-line registration for the 2012 Spring Meeting of Participants will be closed at 4:00 pm on Friday, 20 April 2012. If you have not already registered, you should do so as soon as possible.
Read more ....

2012 Spring Meeting Event -- Cosbie Lecture
We are very pleased to announce Dr. Robert Califf as the 2012 "Cosbie Lecturer". The title of Dr. Califf's talk is "The American Clinical Trials Enterprise: Are We Reaching the Tipping Point for Transformation?"
Read more ....

Next Bulletin
The next edition of the Bulletin will be sent on Thursday, April 26, 2012.
Read more ....

Trial Management Group

Trial Activation
There was one recent trial activation. NCIC CTG MA.34 (BIG 4‐11) -- The APHINITY TRIAL -- was centrally activated April 5, 2012.
Read more ....

Trials Closed to Accrual
Three trials have been closed to accrual -- NCIC CTG PRC.2 (CALGB90202), NCIC CTG IND.200, and NCIC CTG IND.203.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

30 Mar 2012

General

Holiday Closure
The NCIC Clinical Trials Group will be closed on Friday, April 6, 2012 in observance of Good Friday. Regular business hours will resume on Monday, April 9 at 8:00 am EDT.
Read more ....

Trial Management Group

Trial Closed to Accrual
NCIC CTG ES.2 (TROG 03.01) -- A Randomized Phase III Study in Advanced Oesophageal Cancer to Compare Quality of Life and Palliation of Dysphagia in Patients Treated with Radiotherapy Versus Chemo-Radiotherapy -- was closed to accrual on March 21, 2012.
Read more ....

Implementing NCIC CTG Protocol-Specific Training
NCIC CTG, as sponsor in Canada, is required to ensure personnel at our member sites have undergone ICH-GCP and ethical trial conduct training prior to participating on our trials.
Read more ....

NCIC CTG's Lost to Follow-Up Policy
NCIC CTG has developed a new Lost to Follow-Up Policy that we are now pleased to roll out to centres.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

16 Mar 2012

Finance and Operations

2012 Annual Spring Meeting of Participants
The NCIC CTG 2012 Annual Spring Meeting of Participants will be held April 27 - 29, 2012 at the Delta Chelsea Hotel in Toronto.
Read more ....

General

Two NCIC CTG Investigators Recognized by NCI
Dr. Susan Ellard and Dr. Muhammad Salim were recently recognized by the NCI and CTSU for being two of the top-enrolling individual investigators to Cooperative Group treatment trials via the CTSU in 2010.
Read more ....

Trial Closed to Accrual
NCIC CTG IND.187 -- A Phase I Study of AZD2281 in Combination with Irinotecan in Patients with Locally Advanced or Metastatic Incurable Colorectal Cancer -- was closed to accrual on March 8, 2012 after establishing the recommended phase II dose.
Read more ....

Recent Publications
There were four recent publications -- one reporting the primary results of NCIC CTG BL.7 (EORTC 30987), another related to NCIC CTG MA.5, a statistics publication, and another general publication.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

02 Mar 2012

General

Recent Publications
There were 4 recent publications ... one reporting results of NCIC CTG BL.7 (EORTC 30987), one related to NCIC CTG BR.18, one reporting final results of NCIC CTG IND.162, and another related to OV.17 (GINECO CALYPSO).
Read more ....

Dr. Elizabeth Eisenhauer Named NDDO Honorary Award Lecturer
Congratulations to Dr. Elizabeth Eisenhauer for being named the 2012 recipient of the NDDO Honorary Award Lecture for her contributions to cancer drug development.
Read more ....

Trial Management Group

Transition of Leadership of the NCIC CTG CRA Executive
After 7 years of outstanding leadership, Brenda Kowaleski will be stepping down as Chair of the Clinical Research Associates Executive Committee. Succeeding Brenda in this important role will be Lynn Dwernychuk from the Saskatoon Cancer Centre.
Read more ....

Trial Closed to Accrual
NCIC CTG IND.202 - Randomized Phase II Study of Interleukin-21 (rIL-21) versus Dacarbazine (DTIC) in Patients with Metastatic or Recurrent Melanoma - was closed to accrual on February 29, 2012.
Read more ....

CRA Volunteers Needed!
The Clinical Research Associates Executive Committee is actively seeking a CRA representative for a number of the following NCIC CTG Disease Site Committee Executives.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

17 Feb 2012

General

NCIC CTG Central Office and BARL Holiday Closure
The NCIC Clinical Trials Group (Central Office) will be closed on Monday, February 20, 2012 to celebrate Family Day. Bay Area Research Logistics (BARL) will be also closed on Monday for Family Day.
Read more ....

Recent Publications
There were 4 recent publications -- one reporting results of a substudy examining bone strength in a subset of women who participated on NCIC CTG MAP.3; one reporting the health-related quality of life results from NCIC CTG OV.17; and two meta-analyses that included data from NCIC CTG MA.4, MA.5, and MA.21.
Read more ....

2012 Spring Meeting of Participants
The NCIC CTG 2012 Annual Spring Meeting of Participants will be held April 27-29, 2012 at the Delta Chelsea Hotel in Toronto. Full-Funded invitations were sent electronically January 25, 2012, and Non-Funded invitations were sent today, February 17.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

03 Feb 2012

General

NCIC CTG Receives CIHR Funding
We are extremely pleased to announce that the NCIC CTG has received CIHR funding totalling almost $4M to support two NCIC CTG international trials -- CX.5 and GA.1.
Read more ....

Recent Publications
There were four recent publications -- two related to NCIC CTG CO.14 and CO. 15, another related to NCIC CTG BR.21, and the final results of HD.6 are now in print in NEJM.
Read more ....

2011 ASCO Annual Report on Progress Against Cancer
Two NCIC CTG-led trials (MAP.3 and MA.20) and one trial that included NCIC CTG participation (OV.19) were included as "Major Advances" in ASCO's 2011 Annual Report on Progress Against Cancer.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

23 Jan 2012

Finance and Operations

20 January 2012 Bulletin
Due to computer issues, we were unable to send the Bulletin scheduled for Friday, January 20, 2012. As a result, we are sending the Bulletin today ... Monday, January 23. The next Bulletin will be sent as originally planned on Friday, February 3, 2012.
Read more ....

Trial Management Group

Working Group on Economic Analysis Has A New Name
The Working Group on Economic Analysis (WGEA) has a new name! The former WGEA is now the Committee on Economic Analysis (CEA).
Read more ....

CRA Volunteers Needed!
The Clinical Research Associates Executive Committee (CRAEC) is actively seeking a CRA representative for each of the following NCIC CTG Disease Site Committee Executives -- Melanoma, Symptom Control, Gastrointestinal.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton

NCIC CTG Bulletin

06 Jan 2012

General

The NCIC CTG Welcomes New Chairs to Gynecology Committee
We are very pleased to announce that Drs Hal Hirte and Michael Fung Kee Fung are the new Co-Chairs of the NCIC CTG's Gynecology Site Committee. We wish to express our deep gratitude to Drs Gavin Stuart and Amit Oza for their outstanding leadership.
Read more ....

CCS Listing of Top 10 Breakthroughs of 2011
The results of THREE NCIC CTG-led clinical trials were included in the Canadian Cancer Society's listing of the top 10 breakthroughs of 2011.
Read more ....

Recent Publications
There were 4 recent publications -- one related to NCIC CTG MA.5, one related NCIC CTG PA.3, and two other general publications.
Read more ....

Permanent Trial Closures
Following our annual Permanent Trial Closure Assessment, the NCIC CTG has identified those phase I-III NCIC CTG-led trials that will be permanently closed.
Read more ....

NCIC CTG OV.19 (MRC ICON7) in the NEJM
Results of NCIC CTG OV.19 (MRC ICON7) were published in the 29 December 2011 issue of the New England Journal of Medicine.
Read more ....

Trial Management Group

The NCIC CTG Welcomes New Members to the CRA Executive Committee
The NCIC CTG would like to welcome six new members to the newly-formed NCIC CTG Clinical Research Associates Executive Committee.
Read more ....

If you have any questions, comments or suggestions, please contact Heather Stanton